• At least 350 of the 500+ human protein kinases are serine/threonine kinases (STK). (cloudfront.net)
  • Serine/threonine kinases play a role in the regulation of cell proliferation, programmed cell death ( apoptosis ), cell differentiation, and embryonic development. (cloudfront.net)
  • While serine/threonine kinases all phosphorylate serine or threonine residues in their substrates, they select specific residues to phosphorylate on the basis of residues that flank the phosphoacceptor site, which together comprise the consensus sequence . (cloudfront.net)
  • This enzyme belongs to the family of transferases , specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). (alchetron.com)
  • is a kinase enzyme , in particular a protein kinase , that phosphorylates the OH group of the amino-acid residues serine or threonine , which have similar side chains. (cloudfront.net)
  • In enzymology , the term serine/threonine protein kinase describes a class of enzymes in the family of transferases , that transfer phosphates to the oxygen atom of a serine or threonine side chain in proteins . (cloudfront.net)
  • Types include those acting directly as membrane-bound receptors ( Receptor protein serine/threonine kinase ) and intracellular kinases participating in Signal transduction . (cloudfront.net)
  • Sujith Puthiyaveetil, assistant professor of biochemistry, "The Structural Basis of a Serine/Threonine-type Kinase Activity in the Chloroplast Sensor Kinase. (purdue.edu)
  • Kee-Hong Kim, associate professor of food science and an international award-winning nutritional biologist focusing on lipid biochemistry, enzymology and nutritional molecular biology. (purdue.edu)
  • Dominique Mengin-Lecreulx was trained in biochemistry, enzymology, molecular biology and organic chemistry and obtained his PhD degree at the University Paris-Sud in 1987. (degruyter.com)
  • He was trained in organic chemistry, biochemistry and enzymology, and received his PhD degree in natural sciences from the University Paris-Sud in 1979. (degruyter.com)
  • However, THF is not an obligate substrate for SHMT, meaning the cleavage of serine and other β-hydroxy amino acids (such as threonine) can occur without the presence of THF and, in this case, the mechanism is a retro-aldol cleavage. (wikipedia.org)
  • In a distance of 190 kb proximal to D19S886, we identified and characterized a novel human gene encoding the serine threonine kinase STK11. (nih.gov)
  • is a kinase enzyme , in particular a protein kinase , that phosphorylates the OH group of the amino-acid residues serine or threonine , which have similar side chains. (cloudfront.net)
  • At least 350 of the 500+ human protein kinases are serine/threonine kinases (STK). (cloudfront.net)
  • In enzymology , the term serine/threonine protein kinase describes a class of enzymes in the family of transferases , that transfer phosphates to the oxygen atom of a serine or threonine side chain in proteins . (cloudfront.net)
  • Serine/threonine kinases play a role in the regulation of cell proliferation, programmed cell death ( apoptosis ), cell differentiation, and embryonic development. (cloudfront.net)
  • While serine/threonine kinases all phosphorylate serine or threonine residues in their substrates, they select specific residues to phosphorylate on the basis of residues that flank the phosphoacceptor site, which together comprise the consensus sequence . (cloudfront.net)
  • Types include those acting directly as membrane-bound receptors ( Receptor protein serine/threonine kinase ) and intracellular kinases participating in Signal transduction . (cloudfront.net)
  • We showed that the prion domain of Ure2p is the N-terminal 65 amino acid residues, a region rich in asparagine, serine, and threonine. (nih.gov)
  • Histidine protein kinases and serine, threonine, or tyrosine protein kinases play essential roles in signal transduction in prokaryotes and eukaryotes. (cipsm.de)
  • Polo-like kinase 1 (PLK1) is a serine-threonine protein kinase which is overexpressed in cancer cells, and plays a major role in regulating tumor growth. (oncotarget.com)
  • The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease. (nih.gov)