AnatomyOrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceHealth Care
AlanineEnzymesGlutamate-Ammonia LigaseAmino Acyl-tRNA Synthetases2',5'-Oligoadenylate SynthetaseKineticsMolecular Sequence DataAlanine TransaminaseAmino Acid SequenceSubstrate SpecificityBiocatalysisCatalysisAlanine RacemaseEscherichia coliModels, MolecularPeptide SynthasesInterleukin-1betaCoenzyme A LigasesBinding SitesDithioerythritolMethylmalonate-Semialdehyde Dehydrogenase (Acylating)Base SequenceBiosynthetic PathwaysMutationAcyltransferasesLigasesSequence Homology, Amino Acidbeta 2-MicroglobulinAspartate-tRNA LigaseCloning, MolecularMethionine-tRNA LigaseTryptophan-tRNA LigaseProtein ConformationCarbon-Nitrogen LigasesS-AdenosylmethionineModels, ChemicalAlanine DehydrogenaseCatalytic DomainIsoleucine-tRNA LigaseRecombinant ProteinsAspartate-Ammonia LigasePyridoxal PhosphatePhenylalanine-tRNA LigaseOxidation-ReductionGlutamineTyrosine-tRNA LigaseStructure-Activity RelationshipCarbamoyl-Phosphate Synthase (Ammonia)Leucine-tRNA LigaseAdenosine TriphosphateBacterial ProteinsAcyl Coenzyme AHydrogen-Ion ConcentrationCrystallography, X-RaySerine-tRNA LigaseValine-tRNA LigaseMolecular StructureReceptors, Adrenergic, betaAcetate-CoA LigaseArgininosuccinate SynthaseAmino AcidsIntegrin beta3Transfer RNA AminoacylationAlanine-tRNA LigaseSequence AlignmentProtein Structure, TertiarySuccinate-CoA LigasesGlutamate-tRNA LigaseMolecular WeightThreonine-tRNA LigaseGlycine-tRNA LigaseAmide SynthasesGlutathione SynthaseMutagenesis, Site-DirectedRibose-Phosphate PyrophosphokinaseAdenylosuccinate SynthaseOxidoreductasesHydrolysisLiverHistidine-tRNA LigaseProtein BindingCarbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)Glutamate-Cysteine LigaseArginine-tRNA LigaseMagnesiumEnzyme InhibitorsMethionine AdenosyltransferaseEnzyme ActivationCell LineTransforming Growth Factor betaModels, BiologicalRNA, MessengerIron-Sulfur ProteinsAmmoniaSpectrophotometryFatty Acid SynthasesN-Acylneuraminate CytidylyltransferaseAminoacylationFormate-Tetrahydrofolate LigaseFree Radicals
BiosynthesisLevels
Biosynthesis2
  • This enzyme participates in beta-alanine metabolism and pantothenate and CoA biosynthesis. (wikipedia.org)
  • Intracellular steps of bacterial cell wall peptidoglycan biosynthesis: enzymology, antibiotics, and antibiotic resistance. (mcmaster.ca)
Levels2
  • Pharmacokinetic and biological studies, including measurement of the activity of 2',5'-oligoadenylate synthetase (2',5'-OAS) in peripheral blood mononuclear cells and serum levels of soluble Tac (CD 25) and beta-2 microglobulin, were performed on patients who agreed to participate. (nih.gov)
  • Dose-limiting toxicities were encountered during s.c. dosing at the 24-MIU/m2 and 18-MIU/m2 dose levels and included gastrointestinal toxicity, elevations of aspartate aminotransferase and alanine aminotransferase, and albuminuria. (nih.gov)