• protein
  • Significant efforts have been focused on the mechanisms responsible for Aβ production, including the proteolytic enzymes gamma- and β-secretases which generate Aβ from its precursor protein, APP (amyloid precursor protein). (wikipedia.org)
  • The molecule detected by the immunoassay is often referred to as an "analyte" and is in many cases a protein, although it may be other kinds of molecules, of different size and types, as long as the proper antibodies that have the adequate properties for the assay are developed. (wikipedia.org)
  • The theoretical background for protein microarray-based ligand binding assays was further developed by Roger Ekins and colleagues in the late 1980s. (wikipedia.org)
  • The protein encoded by this gene is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A. β-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. (wikipedia.org)
  • 1984). "Enzyme-linked immunosorbent assay for the ganglioside GM2-activator protein. (wikipedia.org)
  • Ubiquitin is a small protein that can be affixed to certain protein substrates by enzymes called E3 ubiquitin ligases. (wikipedia.org)
  • Development
  • Their first product in development was an assay, termed "immunosorbent cytometry", which could be employed to monitor the immune status, i.e., the concentrations and ratios of CD3+, CD4+, and CD8+ T cells, in the blood of HIV-infected individuals. (wikipedia.org)
  • studies
  • Though some animal studies have shown that the absence of Aβ does not lead to any obvious loss of physiological function, several potential activities have been discovered for Aβ, including activation of kinase enzymes, protection against oxidative stress, regulation of cholesterol transport, functioning as a transcription factor, and anti-microbial activity (potentially associated with Aβ's pro-inflammatory activity). (wikipedia.org)
  • Production
  • Also, there is anticipation of industrial enzymes that are engineered to have desirable properties for process improvement as well the manufacturing of high-value biomolecular products at a much lower production cost. (wikipedia.org)
  • multiple
  • CS1 maint: Multiple names: authors list (link) - via ScienceDirect (Subscription may be required or content may be available in libraries. (wikipedia.org)
  • known
  • Aldo-keto reductase family 1, member B1 (AKR1B1), also known as aldose reductase, is an enzyme that in humans is encoded by the AKR1B1 gene. (wikipedia.org)
  • cell
  • Giardia are flagellated protozoans that cause decreased expression of brush border enzymes, morphological changes to the microvillus, and programmed cell death of small intestinal epithelial cells. (wikipedia.org)
  • One such modification is phosphorylation, which happens to many enzymes and structural proteins in the process of cell signaling. (wikipedia.org)
  • cause
  • In some cases these enzymes are exposed to reagents which cause them to produce light or Chemiluminescence. (wikipedia.org)