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  • This enzyme catalyses the following chemical reaction erythromycin D + NADPH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons } erythromycin C + NADP+ + H2O Erythromycin 12 hydroxylase is responsible for the C-12 hydroxylation of the macrolactone ring. (wikipedia.org)
  • The enzyme has a preference for NADPH as the reductant, with NADH being a poor substitute [2]. (enzyme-database.org)
  • Rheumatologic workup for angiotensin-converting enzyme (ACE), rheumatoid factor (RF), uric acid, antineutrophil cytoplasmic antibodies (ANCA), and antinuclear antibody (ANA) were all negative. (aao.org)
  • Common adverse reactions include rhabdomyolysis with myoglobinuria , acute renal failure , myopathy (including myositis ) and liver enzyme abnormalities. (wikidoc.org)
  • The degree of elevation of liver enzymes does not accurately reflect the severity of the liver injury or predict clinical outcome. (bsg.org.uk)
  • Other pathologic organisms responsible for herpes zoster they all may present with distal more than one canister per month for more sensitive to clindamycin and erythromycin, or sensitive sometimes it mimics in neurohospitalist practice the rst rib can compress and damage to the person to report of the aorta, or pda. (easternpropane.com)
  • No virulence factors were detected for any strain and only the non-transferable erm(49) gene, which confers resistance to erythromycin and clindamycin, was identified in the genome of B. longum KABP042. (frontiersin.org)
  • A systematic review concluded that pharmacokinetic and ovulation outcomes support a clinically relevant drug interaction between OCPs and rifampin and, to a lesser extent, rifabutin, but data are limited for other rifamycins. (aafp.org)
  • Another systematic review concluded that current evidence does not support the existence of drug interactions between OCPs and nonrifamycin antibiotics. (aafp.org)
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  • NDM-1 (New-Delhi-Metallo-β-lactamase-1) is an enzyme developed by bacteria that is implicated in bacteria resistance to almost all known antibiotics. (degruyter.com)
  • The main mode of bacterial resistance in case of Gram-negative pathogens is mediated by the expression of enzymes able to hydrolyze this crucial ring: the β-lactamases [ 3 ]. (degruyter.com)
  • RÉSUMÉ Nous avions l'objectif d'étudier la prévalence des effets secondaires causés par les statines chez des patients iraniens admis dans un hôpital spécialisé en cardiologie et sous traitement par statines avant leur hospitalisation. (who.int)
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  • The enzyme involved in the O-demethylation reaction has not been identified. (abchealthonline.com)
  • The enzyme is highly regioselective for the reduction of the endocyclic 1,2-double bond, and is stereoselective, producing only the 1 R -configured product. (enzyme-database.org)
  • The black color and characteristic strong odor are caused by hemoglobin in the blood being altered by digestive enzymes and intestinal bacteria. (tomwademd.net)
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  • Using systematic active surveillance, we enrolled every fifth hospitalized patient at the Infectious Diseases Hospital (IDH) and B.C. Roy Memorial Hospital for Children (BCH) in Kolkata who had diarrhea or dysentery on 2 randomly selected days of the week during May 2009-September 2013. (cdc.gov)
  • thus, clinicians may consider other medications with anticholinergic side e ect o potentially toxic doses are correct according to symptoms of bleeding or lack of administration of broad spectrum antibiotics, including erythromycin and infantile scoliosis in which the patient have resistant hypertension and contributing to anemia of chronic gvhd is multifaceted, involving almost any organ system, the vestibular ocular re ex, and gaithexaminations are normal. (easternpropane.com)
  • Bacterial enzymes, such as beta-lactamase, cannot be broken down by Ampicillin. (ipl.org)
  • To resist the antibiotic, the bacteria needs Beta lactamase that provide the enzyme. (ipl.org)
  • When clavulanic acid is added to amoxicillin, it enhances the agent's bactericidal effect via inactivation of the enzyme beta lactamase. (reviewofoptometry.com)
  • The bacterial plasmid carrying this enzyme disables the Ampicillin placed in the agar, allowing for more bacterial growth. (ipl.org)
  • We expressed human CYP3A4 and four POR variants (Q153R, A287P, R457H, A503 V) in bacteria, reconstituted them in vitro and measured the Michaelis constant and maximum velocity with testosterone, midazolam, quinidine and erythromycin as substrates. (nih.gov)
  • Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. (lookformedical.com)
  • We are now showing the curated evidence used for assigning names and, if possible, gene symbols, publications, and Enzyme Commission numbers on nearly 70% (83 million) microbial RefSeq proteins. (nih.gov)
  • Articles appearing here represent various types of PCD articles that encompass multiple perspectives, from original research and systematic reviews to implementation evaluation to expert commentaries to tools that can be used in public health practice. (cdc.gov)
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  • However, they usually do not survive transit through the stomach and might not resist degradation in the small intestine by hydrolytic enzymes and bile salts and, therefore, might not reach the distal gut [ 7 , 8 ]. (nih.gov)
  • Small molecules and "systematic serendipity" yield big ideas in life-sciences and biomedical research. (harvardmagazine.com)
  • Using systematic active surveillance, we enrolled every fifth hospitalized patient at the Infectious Diseases Hospital (IDH) and B.C. Roy Memorial Hospital for Children (BCH) in Kolkata who had diarrhea or dysentery on 2 randomly selected days of the week during May 2009-September 2013. (cdc.gov)
  • For bosentan and erythromycin, active and passive processes were equally important. (aspetjournals.org)