• oxidative stress
  • Exposure of mast cells to hydrogen peroxide (H2O2) or diamide to mimic oxidative stress unexpectedly increased rather than decreased the intracellular reduced GSH content as well as total GSH in the late phase (i.e., 24 or 48 h after exposure), which was accompanied by an increase in LTC4 release. (sigmaaldrich.com)
  • CbiD
  • Several of these enzymes are pathway-specific: CbiD, CbiG, and CbiK are specific to the anaerobic route of S. typhimurium, whereas CobE, CobF, CobG, CobN, CobS, CobT, and CobW are unique to the aerobic pathway of P. denitrificans. (wikipedia.org)
  • reactive
  • Consistent with the increase in Htt aggregation, PrP C depletion caused an decrease in proteasome activity and a decrease in the activities of cellular defense enzymes compared with control cells whereas reactive oxygen species (ROS) increased more than threefold. (biologists.org)
  • Herein, we demonstrate that among the FoxO3‐regulated genes in NPCs are a host of enzymes in central carbon metabolism that act to combat reactive oxygen species (ROS) by directing the flow of glucose and glutamine carbon into defined metabolic pathways. (embopress.org)
  • novel
  • Authors comment that the cold-activity of this novel enzyme will be useful for therapies in combination with crymotherapy, exposing the target tissue to low temperatures in order to trigger the enzyme activity to activate the drug only where is required. (wikipedia.org)
  • nitrogen
  • This enzyme belongs to the family of ligases, specifically those forming nitrogen-D-metal bonds in coordination complexes. (wikipedia.org)
  • This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds carbon-nitrogen ligases with glutamine as amido-N-donor. (wikipedia.org)
  • chains
  • An ATP-dependent amidase converts the a and c acetate side chains to acetamide, generating nickel(II)-sirohydrochlorin a,c-diamide. (wikipedia.org)
  • activity
  • Moreover, the enzyme could also be used for bioremediation of compounds of explosive and volatile nature in regions where high activity at low temperatures is needed. (wikipedia.org)
  • several
  • In several cases, a homologous enzyme/receptor is addressed, and can potentially be of use in both contexts. (wikipedia.org)
  • appears
  • It appears that this enzyme purified from rat liver lacks haem (and perhaps other components) required for activation by NO, and it should be particularly useful for elucidating the mechanism of action of NO, protoporphyrin IX and other activators. (biochemj.org)
  • either
  • There are about 30 enzymes involved in either pathway, where those involved in the aerobic pathway are prefixed Cob and those of the anaerobic pathway Cbi. (wikipedia.org)
  • potential
  • An example of a potential cold-active enzyme for prodrug therapy was described using a cold-active nitroreductase, Ssap-NtrB (Çelik and Yetis, 2012). (wikipedia.org)
  • presence
  • This study aimed to investigate morphogenesis and secretion of hydrolytic enzymes (phospholipase and proteinase) in the presence of the CE of Eugenia uniflora . (biomedcentral.com)