• disorder
  • Ohio University recently announced it could get tens of millions of dollars in royalty income from the development of two potential blockbuster drugs to treat ovarian cancer and gigantism, a disorder that can result in enlargement of the hands and feet, facial disfiguration and multiple organ disorders, leading to premature death. (foxbusiness.com)
  • However, in 1884, Drs. Christian F. Fritsche and Theodor Albrecht Edwin Klebs (24), supported by the work of Dr. Karl Langer (1872) (25), concluded that in contrast to gigantism, which they considered a congenital disorder, acromegaly is an acquired variety of gigantism that occurs at a later age after growth is completed. (scielo.br)
  • Although various gene mutations have been associated with gigantism, over 50 percent of cases cannot be linked to genetic causes, showing the complex nature of the disorder. (wikipedia.org)
  • syndrome
  • Additionally, a large variety of other known genetic disorders have been found to influence the development of gigantism such as multiple endocrine neoplasia type 1 and 4, McCune-Albright syndrome, Carney complex, familial isolated pituitary adenoma, X-linked acrogigantism (X-LAG). (wikipedia.org)
  • teeth
  • Such deposits form bulbous enlargements on the roots and may interfere with extractions, especially if adjacent teeth become fused (concrescence). (wikipedia.org)