• It is often employed in glowing sticks, chemiluminescent tests in research (such as the enzyme-linked immunosorbent assays (ELISAs)), and in certain kinds that use artificial light. (thenoveldifference.com)
  • Traditional affinity-based immunoassays, such as enzyme-linked immunosorbent assays (ELISAs) 5 , can quantitatively measure antibody titer, but due to inherent complexity and instrumentation, they require a centralized laboratory for diagnostics. (nature.com)
  • Written and edited by leading experts in the field, this unique book places particular emphasis nanoprobes made of luminescent semiconductor nanocrystals (quantum dots or QDs) and magnetic nanoparticles (MNPs). (artechhouse.com)
  • Chemical and Biological Sensing Based on Gold Nanoparticles. (artechhouse.com)
  • His activity at NRL focuses on the development of inorganic nanoparticles and their interfacing with biological systems. (artechhouse.com)
  • Faculty in chemistry and biochemistry explore a variety of topics such as developing novel compounds for medicinal applications, such as cancer and Alzheimers, transportation of contaminants in aquatic environments, bioremediation, multi-functional inorganic solid-state materials, nanoparticles, new materials for energy storage and conversion. (gmu.edu)
  • With the knowledge gained from nanoelectrochemistry, we explore strategies to design complex material platforms that integrate metallic nanoparticles and 2D semiconducting layers to address the challenges in energy conversion chemistry. (gmu.edu)
  • Fluorescent polymer nanoparticles - termed polymer dots, or Pdots, have recently been shown to have sufficient brightness to be visible by a smartphone camera for fluoresence-based assays. (edu.au)
  • The weak emission of AIEgens as molecular species and their bright fluorescence as nanoscopic aggregates differentiate them from conventional organic luminophores and inorganic nanoparticles, making them ideal candidates for optical, electronic, energy and biomedical applications. (european-mrs.com)
  • Nanoparticles have been extensively studied in the past few decades due to the possibilities they offer in applications ranging from medicine to energy generation. (fsu.edu)
  • Each kit includes luciferase reporter cells, an assay plate, all required reagents (optimized culture media, positive-control agonist, and detection reagent), and a detailed Technical Manual. (indigobiosciences.com)
  • Y. Nakajima and Y. Ohmiya, Bioluminescence assays: multicolor luciferase assay, secreted luciferase assay and imaging luciferase assay. (atto.co.jp)
  • In the BL field, we plan to elucidate the luciferin/luciferase systems, biological functions, ecological role, phylogeny, and details of mechanisms of light emission. (fapesp.br)
  • This is useful in biological assays or security detection technologies. (chemistryviews.org)
  • This methodology enables detection of putative metabolites from biological samples and simultaneous quantification of the pattern and extent of isotope labeling. (acs.org)
  • Moreover, this in-depth volume covers assay design and detection, including discussions on the design and implementation of in vitro assay studies using both fluorescence emission and magnetic contast. (artechhouse.com)
  • PolyU's new invention utilizes an optical method called upconversion luminescence resonance energy transfer (LRET) process for ultrasensitive virus detection. (asiaresearchnews.com)
  • Traditional biological methods for flu virus detection include genetic analysis -- reverse transcription-polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA) used in immunology. (asiaresearchnews.com)
  • Such limitations make them difficult for clinical use as a front-line and on-site diagnostic tool for virus detection, paving the way for PolyU's development of the new upconversion nanoparticle biosensor which utilizes luminescent technique in virus detection. (asiaresearchnews.com)
  • The research team has further improved the sensitivity of the luminescent detection method by utilizing a solid phased nanoporous membrane system (NAAO) for virus detection. (asiaresearchnews.com)
  • AAT Bioquest are well known for their photometric detection fluorescence and luminescent technologies. (stratech.co.uk)
  • In the past decades, gold and silver nanoclusters (Au NCs and Ag NCs) have been massively explored and utilized in the field of industrial catalysis, optoelectronic devices, biological imaging, environmental detection, clinical diagnoses, and treatment. (hindawi.com)
  • You also learn how to use luminescent QDs to design fluorescence resonance energy transfer (FRET) investigations. (artechhouse.com)
  • In comparison to conventional downconversion luminescent technique, it causes low damage to genetic materials and does not induce background fluorescence. (asiaresearchnews.com)
  • FP Fluor™ superior fluorescent labelling dyes, optimised for developing fluorescence polarisation-based assays. (stratech.co.uk)
  • Pdots with near-infrared fluorescence capable of selective binding to breast cancer cells suitable for imaging in the biological transparency window (650 - 1350 nm) will be demonstrated. (edu.au)
  • New Pdot technologies taing advantage of thermally activated delayed fluorescence (TADF) for time-gated imaging will also be described, allowing one to eliminate background fluorescence from biological tissues or secondary dyes. (edu.au)
  • You find an insightful discussion on the synthesis, characterization, and analysis of the unique properties of luminescent QDs and MNPs. (artechhouse.com)
  • however, the study of ultrafine Pt NCs is at the beginning stage and there are still plenty of challenges like synthesis of near-infrared (NIR) fluorescent Pt NCs, the explicit signal pathway of cell apoptosis, and attempt in diverse biological applications that need to be urgently tackled in future. (hindawi.com)
  • 1 Current assays used for screening of potential inhibitors of these enzyme classes rely on unstable antibodies or chemically labelled substrates, which prevents real-time analysis and makes the accurate determination of enzyme kinetics more difficult. (edu.au)
  • In the field of immunodiagnostics, antibodies are used to quantify clinical biomarkers in complex biological samples like blood (Wild, 2013). (trea.com)
  • To achieve this goal, we designed an assay that focuses on antibodies competing with RBD:ACE-2 interactions as a proxy for antibody neutralization 8 (Fig. 1a,b ). (nature.com)
  • bioluminescence is a biological process only found in certain species of organisms. (thenoveldifference.com)
  • Bioluminescence is a biological phenomenon where living organisms generate visible light by an enzymatic reaction inside their bodies. (thenoveldifference.com)
  • Bioluminescence is a biological process. (thenoveldifference.com)
  • M. Yasunaga, Y. Nakajima and Y. Ohmiya, Dual-color bioluminescence imaging assay using green- and red-emitting beetle luciferases at subcellular resolution. (atto.co.jp)
  • PolyU's researchers have developed a biosensor based on luminescent technique which operates like two matching pieces of magnet with attraction force. (asiaresearchnews.com)
  • With INDIGO's in vitro drug discovery assays, save resources and energy by identifying and characterizing adverse effects and potential risks before your drug candidate progresses further in the drug development process. (indigobiosciences.com)
  • In vitro and in vivo (animal and human) studies utilized a variety of LED wavelength, power intensity, and energy density parameters to begin to identify conditions for each biological tissue that are optimal for biostimulation. (researchgate.net)
  • A membrane receptor reagent and assay is disclosed in which liposomes are bound to an evanescent wave emitting surface. (google.com)
  • Or dig deeper downstream of nuclear receptor activation through quantification of gene expression using INDIGO's assay services. (indigobiosciences.com)
  • Identify therapeutic agents with the highest selectivity and lowest potential for off-target and unwanted effects with INDIGO's cell-based receptor assays. (indigobiosciences.com)
  • However, despite growing biological and clinical significance, little is known about the structural arrangement of this receptor or any of its family members. (uci.edu)
  • In homogeneous immunoassays, the antibody reacts with the analyte in solution, which allows much faster assay times. (trea.com)
  • However in contrast to heterogeneous immunoassays, homogeneous immunoassays have problems in signal generation, which so far results in less sensitive assays. (trea.com)
  • Because the steady state of this reaction can be reached already after 90 seconds, this assay is highly attractive for clinical point of care testing (POCT). (trea.com)
  • In a double-anonymized randomized study it was found that there was 70% improvement of clinical symptoms of allergic rhinitis after intranasal illumination by low-energy narrow-band phototherapy at a wavelength of 660 nm three times a day for 14 consecutive days. (researchgate.net)
  • The analogue of Au and Ag NCs and platinum nanoclusters (Pt NCs), especially their biological applications, is relatively and rarely discussed. (hindawi.com)
  • Here, we describe the use of bidentate lipoic acid ligands in the one phase growth of luminescent gold and silver nanoclusters. (fsu.edu)
  • Evaluate your compounds on major receptors with INDIGO's reporter assay panels to understand their biological and toxicological effects better. (indigobiosciences.com)
  • It happens when certain chemical compounds, also known as chemiluminescent substances or molecules undergo chemical reactions and release light energy as photons (light). (thenoveldifference.com)
  • ATP, ADP, AMP) play crucial roles in a range of biological processes including energy transduction, cellular signalling and membrane transport. (edu.au)
  • Mitochondrion is a common membrane-coated organelle that participates in energy conversion, homeostasis of calcium, cell signaling and cell death. (rsc.org)
  • The reaction is triggered by the excitation of electrons in molecules, and then returning them to their lower energy level and releasing energy through visible light. (thenoveldifference.com)
  • They provide energy and matter for living beings, but charge a high price - diseases, ageing, death -, via electron-transfer reactions and electronic photo- and chemiexcitation of molecules. (fapesp.br)
  • Particular importance here is the biological applications of Pt NCs such as the bioimaging of various cells as a preferred fluorophore in contrast to traditional fluorescent markers (e.g., organic dye, semiconductor quantum dots, and fluorescent proteins), the usage of Pt NCs-based antitumour drugs as a new class chemotherapeutics for malignant tumour therapy, and the utilization of antibacteria as an alternative of Ag-based antibacterial agent. (hindawi.com)
  • Recently, gold nanorods (GNRs) have attracted growing interest in biological/biomedical applications. (springer.com)
  • The conceptualization of aggregation-induced emission (AIE) breaks this common belief and provides a new stage for the exploration of practically useful luminescent materials for optical, electronic, energy and biomedical applications. (european-mrs.com)
  • Antibody neutralizing capabilities are traditionally measured in cell-based live viral infection assays that require BSL3 facilities 6 . (nature.com)
  • Our coupling approach does not require target modification and can better distinguish sample-to-sample differences in analyte binding affinity and abundance than traditional competition-based assays. (nature.com)
  • We are developing luminescent europium(III) complexes 2-6 capable of reversibly binding and discriminating between nucleoside tri-, di- and monophosphate anions in aqueous biological media (Figure 1). (edu.au)
  • In this project, we explored the strategies to synthesize luminescent metallic clusters of gold and silver and to promote their solubility and stability in aqueous and biological medium. (fsu.edu)
  • Cell Meter™ cellular functional assay kits, a complete set of tools for functional analysis of cellular events. (stratech.co.uk)
  • Screen Quest™ assay kits, a set of HTS-ready tools for high throughput screening of biochemical and cellular targets such as protein kinases, proteases, HDAC, cell apoptosis and cytoxicity, GPCR, ion channels, ADME/metabolism and transporters. (stratech.co.uk)
  • Mitochondria play an important role in supplying cellular energy, cell signaling and governing cell death. (rsc.org)
  • Chemical mechanisms, biological functions and technological uses of BL fungi and marine animals will be investigated. (fapesp.br)
  • a a Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P. R. China. (rsc.org)
  • The journal is indexed by Clarivate Analytics services (Biological Abstract, BIOSIS Previews) and has an Impact Factor (June 2023) of 1.5 . (pan.pl)
  • We aimed to develop a sensor technology that can quantitatively measure nAb responses against different isolates of SARS-CoV-2, be adapted for an all-in-solution multiwell format and provide rapid results in 1 hour, which is faster than established ELISA assays measuring SARS-CoV-2 antibody titer (~6 hours) or cell-based neutralization assays (~one to several days). (nature.com)
  • We have designed, built, and laboratory-tested a unique shield design that transforms the complex neutron spectrum from PuBe source neutrons, generated at high energies, to nearly exactly the neutron signature leaking from a significant spherical mass of weapons grade plutonium (WGPu). (spie.org)
  • Trouble-shoot with INDIGO's large portfolio of ortholog assays to quickly determine if the response observed in laboratory animals is concordant with humans. (indigobiosciences.com)
  • The objectives of Phase I are (1) to construct a proof-of-principle generator for operation at 125 kV, (2) to experimentally demonstrate that a uniform, high energy ion beam can be generated, and (3) to develop the conceptual design for a Phase II laboratory prototype DNG system. (nsf.gov)
  • These clusters are interesting because of their potential applications in field such as sensing, imaging, catalysis, clean energy, photonics, etc. as well as they provide fundamental insight into the evolution of the optical and electronic properties of these clusters. (fsu.edu)
  • He remained at Queen's to pursue a Ph.D. in Inorganic Chemistry focusing on the development of luminescent materials for organic electronics. (edu.au)
  • He leads a research program in synthetic materials chemistry, studying topics ranging from solutions for energy-efficient displays and light sources to the self-assembly of electronic materials on the nanoscale. (edu.au)
  • Plasmon-Resonant Gold Nanorods: Photophysical Properties Applied Toward Biological Imaging and Therapy. (artechhouse.com)
  • Its pathophysiological mechanisms involve various biological events such as neuronal apoptosis, oxidative stress, endoplasmic reticulum stress and inflammatory cascade[ 2 - 5 ]. (ijpsonline.com)
  • The complicated energy level structure of lanthanide ions can be an asset and not a disadvantage, if one can precisely navigate the energy transfer pathways within single lanthanide ions to favor discrete energy transitions. (nature.com)
  • Moreover, M NCs exhibit the intense light absorption and emission by the interaction between NCs and light via electronic transitions between energy levels. (hindawi.com)
  • In addition, gamma-ray spectrometers made from iodine-based compound semiconductor materials have demonstrated energy resolutions (FWHM) less than 2% at 662 keV. (spie.org)
  • This equivalent "X-material shield assembly" (Patent Pending) enables the harder PuBe source spectrum (average energy of 4.61 MeV) from a small encapsulated standard 1-Ci PuBe source to be transformed, through interactions in the shield, so that leakage neutrons are shifted in energy and yield to become a close reproduction of the neutron spectrum leaking from a large subcritical mass of WGPu metal (mean energy 2.11 MeV). (spie.org)
  • Thiol yield percentage was quantified using ellman assay. (fsu.edu)
  • When deciding on what to study for my PhD, I became fascinated by synthetic biology, the idea that biological systems can be rewired both to solve real world problems and to yield insight into how biological systems work. (wrfseattle.org)
  • 18/25842-8 - Sources, Targets and Biological Responses of Triplet Species and Singlet Oxygen: Pathogenicity and Quenching. (fapesp.br)
  • While typical UCNPs produce multiple simultaneous emissions for unidirectional control of biological processes, programmable control requires orthogonal non-overlapping light emissions. (nature.com)
  • He leads a group synthesising lanthanide-based molecular probes for the purpose of sensing biological anions, probing enzyme activity, and monitoring fluctuations in target species in living cells. (edu.au)
  • In the early stage of ischemia and hypoxia, cells will increase the energy supply to the ischemic area, especially the functional area of the ischemic penumbra, by regulating glycolysis. (ijpsonline.com)
  • Single Particle Investigation of Biological Processes Using QD-Bioconjugates. (artechhouse.com)
  • However, traditional UCNPs give out single colored emissions or simultaneously emit multiple colored signals under 980 nm excitation, which are only suitable for mono-directional modulations of biological processes. (nature.com)
  • The energy transition processes for green emissions and red emissions of Er 3+ ions simultaneously occur after the photon is pumped into excited states in the typical UCNPs. (nature.com)
  • We conclude that further development of targeted approaches should prevent inaccurate conclusions about the nature of biological regulations and in particular kinase-substrate networks. (acs.org)
  • It represents the culmination of basic and applied research to solve the problem of generating a biological system that can detect, identify and neutralize target biological agents in a seamless manner. (conceptualmindworks.com)
  • They are composed of an activation core (C) which is co-doped with Yb 3+ and a Ln 3+ activator, an energy relay layer (S1), an energy absorbance region (S2), and an inert outer layer (S3). (chemistryviews.org)
  • Herein, we explore cross-relaxation (CR), a non-radiative recombination pathway typically perceived as deleterious, to manipulate energy migration within the same lanthanide activator ion (Er 3+ ) towards orthogonal red and green emissions, simply by adjusting excitation wavelength from 980 to 808 nm. (nature.com)
  • Owing to the complex energy level structures of these ions and the propensity for crosstalk, these activator ions need to be spatially segregated into separate layers in the resulting nanocrystals. (nature.com)
  • Nanoscale science, engineering and technology have enabled numerous advances that provide promises for sustainable agriculture and food system by the convergency of physical and biological sciences, biotechnology, information sciences, social sciences, and other disciplines. (pittcon.org)
  • Advanced environmental controls, including CO 2 /O 2 control, incubation to 70 °C, and variable shaking support live cell assays. (agilent.com)
  • studying them can shed light on an interesting aspect of biological and physical sciences. (thenoveldifference.com)
  • Upon addition of RBD, the free energy of binding to lucCageRBD, together with that of lucKey, drives switch opening and generation of luminescent signal (Fig. 1b ). (nature.com)
  • Quickly gain insights into the mechanisms underlying the involvement of key receptors in various diseases with INDIGO's reporter assays. (indigobiosciences.com)
  • With a patented combination of monochromator and filter optics, Synergy Neo2 an advanced plate reader delivering flexibility and performance for any microplate assay. (agilent.com)