Endothelium, VascularVasodilationVasodilator AgentsBrachial ArteryNitric Oxide Synthase Type IIINitric OxideAcetylcholineNitroprussideVascular DiseasesOxidative StressNitroglycerinErectile DysfunctionEndothelial CellsSuperoxidesForearmVentricular Dysfunction, LeftAortaNitric Oxide SynthaseRegional Blood FlowArginineCoronary VesselsBiological MarkersBiopterinNADPH OxidaseBlood PressureReactive Oxygen SpeciesAtherosclerosisVasoconstrictionVasomotor SystemHypertensionHyperemiaDisease Models, AnimalEndothelium-Dependent Relaxing FactorsAorta, ThoracicDiabetic AngiopathiesCardiovascular DiseasesVasoconstrictor AgentsInflammationPlethysmographyMicrocirculationDose-Response Relationship, DrugAntioxidantsomega-N-MethylarginineHyperhomocysteinemiaMesenteric ArteriesEndothelin-1Risk FactorsC-Reactive ProteinArteriosclerosisHypercholesterolemiaCoronary CirculationBlood Flow VelocityHomocysteineEnzyme InhibitorsMice, Inbred C57BLDiabetes Mellitus, Type 2Time FactorsCoronary Artery DiseasePeroxynitrous AcidCells, CulturedImpotence, VasculogenicEndotheliumNG-Nitroarginine Methyl EsterArteriesRats, Sprague-DawleyVascular ResistanceSuperoxide DismutaseVascular Cell Adhesion Molecule-1Cross-Over StudiesCase-Control StudiesScavenger Receptors, Class EPre-EclampsiaRats, WistarDiabetes Mellitus, ExperimentalAgingArginaseNitratesGTP CyclohydrolaseCarotid ArteriesHemodynamicsCell-Derived MicroparticlesAscorbic AcidMice, KnockoutIntercellular Adhesion Molecule-1HyperglycemiaHydroxymethylglutaryl-CoA Reductase InhibitorsArteriolesRats, Inbred SHRInsulin ResistanceSodium NitriteCyclic N-OxidesHuman Umbilical Vein Endothelial CellsVentricular DysfunctionFree Radical ScavengersE-SelectinMyographyHeart FailureSexual Dysfunction, PhysiologicalAcetophenonesNitric Oxide Synthase Type II