• gene
  • When melanoma and endothelioma cells were cultured on either side of a Nucleopore membrane, the expression of VCAM-1 on the endothelioma cells was inhibited and VCAM-1 gene transcription was suppressed. (rupress.org)
  • or on the cytokine-stimulated upregulation of ICAM-1, an NF-κB target gene, in endothelial cells. (jimmunol.org)
  • mechanism
  • Since metastases are rarely cleared by blood-borne cells from the immune system, we asked whether the tumor may escape host defense by interfering with the mechanism of effector cell extravasation. (rupress.org)
  • We propose that the downregulation of VCAM-1 is a mechanism by which vascularized melanoma and carcinoma avoid invasion by cytotoxic cells of the immune system. (rupress.org)
  • However, the mechanism by which PECAM-1, and specifically endothelial PECAM-1, is protective against exaggerated inflammation is poorly understood. (jimmunol.org)
  • group
  • Fluorescein microscopy one month after surgery showed numerous DiI-labelled cells on the posterior corneal surface in the DSAEK group. (mdpi.com)