• fracture
  • Many other conditions were once confused with OCD when attempting to describe how the disease affected the joint, including osteochondral fracture, osteonecrosis, accessory ossification center, osteochondrosis, and hereditary epiphyseal dysplasia. (wikipedia.org)
  • avascular
  • Despite much research, the causes remain unclear but include repetitive physical trauma, ischemia (restriction of blood flow), hereditary and endocrine factors, avascular necrosis (loss of blood flow), rapid growth, deficiencies and imbalances in the ratio of calcium to phosphorus, and problems of bone formation. (wikipedia.org)
  • secondary
  • Secondary ossification mostly occurs after birth (except for distal femur and proximal tibia which occurs during 9th month of fetal development). (wikipedia.org)
  • formation
  • Nevertheless, old age, many diseases and medicines can disturb the balance, ultimately the breakdown process exceeds the bone formation, and as a result, trabecular plates of bone are destroyed causing weakness of the structure of bone with greatly reduced bone mass. (intechopen.com)
  • As demonstrated from murine studies, expression of both SHH and IHH is critical to the formation and fusion of the cranial sutures and calvarial ossification. (frontiersin.org)
  • These data indicate an unexpected role in vertebral segmentation, joint formation and endochondral ossification for this ubiquitously expressed cytoskeletal protein. (jove.com)
  • Heterotopic ossification is a process resulting in the formation of bone tissue that is often atypical, at an extraskeletal location. (wikipedia.org)
  • plate's
  • The purpose of this work was to study the involvement of MMP-2, -3, -9, -13, and -16 in the growth plate's response to loading and in the catch-up growth resulting from load release. (physiology.org)
  • These results demonstrate the central role of MMPs in the growth plate's response to mechanical loading, as well as in the catch-up growth followed load release. (physiology.org)
  • fibroblast
  • These 3 relatively common entities are known to be allelic to the same gene: the fibroblast growth factor receptor 3 gene on chromosome 4p. (eurorad.org)
  • grows
  • The growth rate is not steady, and occasionally a lesion grows more rapidly than expected. (hindawi.com)
  • that is, the whole bone is alive, with maintenance remodeling throughout its existing bone tissue, but the growth plate is the place where the long bone grows longer (adds length). (wikipedia.org)
  • roles
  • Pubmed ID: 11854453 Receptors for bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta (TGFbeta) superfamily, are persistently expressed during cardiac development, yet mice lacking type II or type IA BMP receptors die at gastrulation and cannot be used to assess potential later roles in creation of the heart. (jove.com)
  • mice
  • Not like human or rabbit, the expression of estrogen receptors within HZ of growth plate in mice and rat was extremely low until at the last time point prior to epiphyseal fusion, which also reflects the less effect of estradiol cypionate to in the HZ in our study. (naturalheightgrowth.com)
  • marrow
  • Trabecular marrow is composed of a network of rod- and plate-like elements that make the overall organ lighter and allow room for blood vessels and marrow. (wikipedia.org)