Encodes family protein kinase inhibitors. Medical search. Frequent questions

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Anatomy16

Cells, Cultured Cell Line Tumor Cells, Cultured Cell Line, Tumor 3T3 Cells HeLa Cells Cell Nucleus Cytosol Fibroblasts Cell Membrane Neurons PC12 Cells Myocardium Epithelial Cells CHO Cells Muscle, Smooth, Vascular

Organisms7

Rats, Sprague-Dawley Cattle Rabbits Rats, Wistar Cricetinae Mice, Inbred C57BL Mice, Knockout

Chemicals and Drugs166

Protein-Serine-Threonine Kinases Protein Kinase Inhibitors Protein Kinase C Protein Kinases Cyclic AMP-Dependent Protein Kinases Staurosporine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Enzyme Inhibitors Calcium-Calmodulin-Dependent Protein Kinases Mitogen-Activated Protein Kinases p38 Mitogen-Activated Protein Kinases Isoquinolines Phosphatidylinositol 3-Kinases Alkaloids Indole Alkaloids Protein-Tyrosine Kinases Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinase Kinases Carbazoles Mitogen-Activated Protein Kinase 3 JNK Mitogen-Activated Protein Kinases Tetradecanoylphorbol Acetate Piperazines Cyclic GMP-Dependent Protein Kinases Cyclic AMP Protein Kinase C-alpha src-Family Kinases Indoles Protein Kinase C-delta Pyridines Intracellular Signaling Peptides and Proteins Isoenzymes AMP-Activated Protein Kinases Cyclin-Dependent Kinases Pyrimidines Proto-Oncogene Proteins Genistein Calcium Phosphoproteins Carrier Proteins RNA, Messenger Flavonoids Protein Kinase C-epsilon CDC2 Protein Kinase Protein Kinase C beta Maleimides Casein Kinase II Imidazoles Cyclin-Dependent Kinase Inhibitor p27 Proto-Oncogene Proteins c-akt Sulfonamides Cyclin-Dependent Kinase Inhibitor p21 Calcium-Calmodulin-Dependent Protein Kinase Type 2 Extracellular Signal-Regulated MAP Kinases MAP Kinase Kinase 1 Recombinant Proteins Chromones Androstadienes DNA-Binding Proteins Okadaic Acid Antineoplastic Agents Benzamides Serine Phorbol 12,13-Dibutyrate Phorbol Esters Morpholines rho-Associated Kinases MAP Kinase Kinase Kinases Casein Kinases Adenosine Triphosphate Transcription Factors Tyrosine Recombinant Fusion Proteins Proto-Oncogene Proteins c-bcl-2 Phosphoprotein Phosphatases Diglycerides Cell Cycle Proteins p21-Activated Kinases Cyclic AMP-Dependent Protein Kinase Type II eIF-2 Kinase Butadienes Membrane Proteins Nitriles Nuclear Proteins Ribosomal Protein S6 Kinases MAP Kinase Kinase 4 Receptor Protein-Tyrosine Kinases Receptor, Epidermal Growth Factor Pyrroles Ethers, Cyclic Proteins Phosphotransferases (Alcohol Group Acceptor)Naphthalenes Colforsin Protamine Kinase Isoflavones Quinazolines Cyclic GMP Benzophenanthridines Aurora Kinases Cyclins Mitogen-Activated Protein Kinase 14 Glycogen Synthase Kinase 3 Phenanthridines Actins Myosin-Light-Chain Kinase Tyrphostins DNA-Activated Protein Kinase 2-Aminopurine DNA Primers RNA, Small Interfering NF-kappa B Pyrazoles 8-Bromo Cyclic Adenosine Monophosphate CDC2-CDC28 Kinases 3-Phosphoinositide-Dependent Protein Kinases Threonine Creatine Kinase Phosphotyrosine Tumor Suppressor Proteins Thiazoles Thionucleotides Peptides Pyruvate Kinase Adaptor Proteins, Signal Transducing DNA bcl-X Protein Ribosomal Protein S6 Kinases, 90-kDa Diacylglycerol Kinase Mitogen-Activated Protein Kinase 8 Phosphoserine I-kappa B Kinase MAP Kinase Kinase 2 MAP Kinase Kinase Kinase 1 Cyclic AMP Response Element-Binding Protein Calmodulin Protein Isoforms Tumor Necrosis Factor-alpha Trans-Activators Epidermal Growth Factor 1-Phosphatidylinositol 4-Kinase bcl-2-Associated X Protein Thymidine Kinase TOR Serine-Threonine Kinases Cyclin-Dependent Kinase Inhibitor p57 Oxazoles DNA, Complementary Caspases Cyclin-Dependent Kinase 2 Focal Adhesion Protein-Tyrosine Kinases 1-Methyl-3-isobutylxanthine Cyclin-Dependent Kinase Inhibitor Proteins Kinetin Transcription Factor AP-1 Bucladesine Focal Adhesion Kinase 1 Insulin Proto-Oncogene Proteins c-jun Type C Phospholipases GTP-Binding Proteins Proto-Oncogene Proteins c-fos Apoptosis Regulatory Proteins Caspase 3 Microtubule-Associated Proteins Multienzyme Complexes Cycloheximide

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Transfection Blotting, Western Immunoblotting Models, Biological Cloning, Molecular Precipitin Tests Reverse Transcriptase Polymerase Chain Reaction Mutagenesis, Site-Directed Models, Molecular Electrophoresis, Polyacrylamide Gel Microscopy, Fluorescence Sequence Alignment Blotting, Northern Inhibitory Concentration 50 Two-Hybrid System Techniques Immunohistochemistry

Phenomena and Processes47

Phosphorylation Enzyme Activation Signal Transduction MAP Kinase Signaling System Amino Acid Sequence Apoptosis Kinetics Protein Binding Transfection Mutation Dose-Response Relationship, Drug Base Sequence Cell Division Protein Structure, Tertiary Binding Sites Gene Expression Regulation Substrate Specificity Cell Cycle Time Factors Sequence Homology, Amino Acid Transcription, Genetic Down-Regulation Cell Proliferation Cell Survival Gene Expression Regulation, Enzymologic Up-Regulation Gene Expression Promoter Regions, Genetic Cell Differentiation Protein Transport Second Messenger Systems Biological Transport Drug Synergism Transcriptional Activation Structure-Activity Relationship Molecular Weight Mitosis Drug Resistance, Neoplasm Cell Movement Enzyme Induction G1 Phase RNA Interference Protein Processing, Post-Translational Inhibitory Concentration 50 Gene Expression Regulation, Neoplastic Amino Acid Motifs Cell Adhesion

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science

Protein-Serine-Threonine Kinases Protein Kinase Inhibitors Protein Kinase C Protein Kinases Cyclic AMP-Dependent Protein Kinases Phosphorylation Staurosporine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Enzyme Inhibitors Calcium-Calmodulin-Dependent Protein Kinases Mitogen-Activated Protein Kinases p38 Mitogen-Activated Protein Kinases Isoquinolines Enzyme Activation Signal Transduction Phosphatidylinositol 3-Kinases MAP Kinase Signaling System Alkaloids Indole Alkaloids Protein-Tyrosine Kinases Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinase Kinases Molecular Sequence Data Carbazoles Mitogen-Activated Protein Kinase 3 Cells, Cultured Cell Line JNK Mitogen-Activated Protein Kinases Tetradecanoylphorbol Acetate Amino Acid Sequence Piperazines Cyclic GMP-Dependent Protein Kinases Cyclic AMP Protein Kinase C-alpha src-Family Kinases Indoles Protein Kinase C-delta Apoptosis Pyridines Intracellular Signaling Peptides and Proteins Isoenzymes Kinetics Protein Binding AMP-Activated Protein Kinases Cyclin-Dependent Kinases Pyrimidines Proto-Oncogene Proteins Genistein Calcium Transfection Phosphoproteins Carrier Proteins Blotting, Western RNA, Messenger Flavonoids Protein Kinase C-epsilon Tumor Cells, Cultured CDC2 Protein Kinase Protein Kinase C beta Mutation Cell Line, Tumor Dose-Response Relationship, Drug Maleimides Casein Kinase II Imidazoles Cyclin-Dependent Kinase Inhibitor p27 Base Sequence Proto-Oncogene Proteins c-akt Sulfonamides Cyclin-Dependent Kinase Inhibitor p21 Calcium-Calmodulin-Dependent Protein Kinase Type 2 Extracellular Signal-Regulated MAP Kinases MAP Kinase Kinase 1 Cell Division Recombinant Proteins Chromones Androstadienes Protein Structure, Tertiary Binding Sites DNA-Binding Proteins Okadaic Acid Gene Expression Regulation Antineoplastic Agents Benzamides Substrate Specificity Serine Phorbol 12,13-Dibutyrate Phorbol Esters Morpholines rho-Associated Kinases MAP Kinase Kinase Kinases Cell Cycle Casein Kinases Time Factors Adenosine Triphosphate Transcription Factors Sequence Homology, Amino Acid Tyrosine Recombinant Fusion Proteins Proto-Oncogene Proteins c-bcl-2

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