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  • utero
  • CONCLUSIONS: Unless the in utero development of dermatoglyphics in relation to blood pressure is substantially different between singleton and twin pregnancies, there are no useful relationships between dermatoglyphics and hypertension or strong relationships between the presence of certain 'dermatoglyphic markers of impaired fetal development' and blood pressure in subjects who remain normotensive until early in their seventh decade. (biomedsearch.com)
  • Number of conceptuses in utero affects porcine fetal muscle development. (semanticscholar.org)
  • The association of in utero exposure to such carcinogens and the subsequent development of cancer has been reported for all childhood cancers combined and particularly for childhood acute lymphoblastic leukemia, lymphoma, and brain tumors. (wikipedia.org)
  • occurs
  • For example, it has been proven that during exposure nicotine binds to receptors of the fetal cells through which developmentally important signaling occurs in many developing organs and tissues. (wikipedia.org)
  • Cherry angioma may occur through two different mechanisms: angiogenesis (the formation of new blood vessels from pre-existing vessels), and vasculogenesis (the formation of totally new vessels, which usually occurs during embryonic and fetal development). (wikipedia.org)
  • human
  • Layer I, also called the plexiform layer because of the richness in fibers and the paucity of cells, was initially described in the human fetal cerebrum ( Magini, 1888 ). (jneurosci.org)
  • The present study was undertaken to analyze the development and organization of cortical layer I in macaque monkey using [ 3 H]thymidine autoradiography, electron microscopy, immunohistochemistry, and in situ hybridization methods that cannot be used effectively in the postmortem human brain. (jneurosci.org)
  • Early
  • It has been shown that both FBN-1 and FBN-2, along with the other components of elastic fibers, are expressed in the embryonic semilunar valves as early as 4 weeks of gestation. (wikipedia.org)
  • This supports the idea that fibrilin-2 dictates the development of early elastic fibers, while fibrillin-1 provides the structural support of mature elastic fibers. (wikipedia.org)
  • 2002
  • She accepted a one-year position as director of the university's Center for Community Outreach and Development from 2002 to 2003. (wikipedia.org)
  • somatic
  • Embryonic somatic nerve destruction with beta-bungarotoxin. (biomedsearch.com)
  • The effects and time course of a single injection of beta-bungarotoxin into E14 rat embryos were examined with an electron-microscopic study of development of the internal intercostal somatic nerve. (biomedsearch.com)
  • The production of Dolly showed that genes in the nucleus of such a mature differentiated somatic cell are still capable of reverting to an embryonic totipotent state, creating a cell that can then go on to develop into any part of an animal. (wikipedia.org)
  • cell
  • The study confirms that sensory and motor neurons are much less able to survive axon degeneration on E14 than after the major period of normal cell death (which is nearly over by E18), and that the maintenance and continued development of the perineurium during E14-E16 depends on the presence of peripheral nerve axons. (biomedsearch.com)
  • By inhibiting mir-424 in normal endothelial cells they could observe the same increased protein expression of MEK1 and cyclin E1 which, important for the development of senile hemangioma, induced cell proliferation of the endothelial cells. (wikipedia.org)
  • research
  • Reynolds began teaching in the College of Medicine at the University of Illinois in 1965, where she also conducted research on embryonic and fetal development, child nutrition, and pancreatic disease. (wikipedia.org)
  • Current psychiatric research into the development of the disorder is often based on a neurodevelopmental model (proponents of which see schizophrenia as a syndrome. (wikipedia.org)
  • cells
  • The reprogramming process that cells need to go through during cloning is not perfect and embryos produced by nuclear transfer often show abnormal development. (wikipedia.org)
  • Because the binding of these receptors is unanticipated by the regulated activity of the fetal cells it can be inferred that this is a disruption in the cellular process which can lead to detrimental effects such as the deregulation of vital signaling, expression, or repair. (wikipedia.org)
  • phenotype
  • Further, the use of these knockout models determined the significance of Tbx2 in the BMP signaling pathway for development of the atrioventricular canal, atrioventricular nodal phenotype, and atrioventricular cushion. (wikipedia.org)
  • Terms
  • Tbx2 and Tbx3 are the only T-box transcription factors that act as transcriptional repressors rather than transcriptional activators, and are closely related in terms of development and tumorigenesis. (wikipedia.org)
  • Further
  • At a certain point, Tbx2 concentrations are such that the signaling of Shh and FGF are terminated, halting further progression and outgrowth of the limb development. (wikipedia.org)
  • embryos
  • In 2001, the British Parliament amended the Human Fertilisation and Embryology Act 1990 (since amended by the Human Fertilisation and Embryology Act 2008) to permit the destruction of embryos for hESC harvests but only if the research satisfies one of the following requirements: Increases knowledge about the development of embryos, Increases knowledge about serious disease, or Enables any such knowledge to be applied in developing treatments for serious disease. (wikipedia.org)
  • Mouse embryos overexpressing H19 tend to die between embryonic day 14 and birth. (wikipedia.org)
  • gestation
  • To promote the long-term culture of the embryonic heart at late stages of gestation, we developed a protocol in which the excised heart is cultured in a semi-solid, dilute Matrigel. (jove.com)
  • After 13 weeks of gestation, the fetal age may be estimated using the biparietal diameter (the transverse diameter of the head, across the two parietal bones), the head circumference, the length of the femur, the crown-heel length (head to heel), and other fetal parameters. (wikipedia.org)
  • suggests
  • This suggests that a decrease in adiponectin production in obese individuals may represent an important causative factor in the development and/or propagation of the insulin resistance, diabetes, and, potentially, other metabolic diseases. (pubmedcentralcanada.ca)
  • As the name suggests, anamniotes do not develop an amnion during fetal life and are able to exchange oxygen, carbon dioxide and waste metabolites with the surrounding water. (wikipedia.org)
  • humans
  • In humans, the 561 amino acid EFS protein acts as a scaffolding protein for cell signaling based on interactions with SRC, FAK, and other proteins, and has been linked to roles in the function of the immune system, and the development of cancer. (wikipedia.org)
  • The let-7 RNA was found to be conserved in many species, leading to the suggestion that let-7 RNA and additional "small temporal RNAs" might regulate the timing of development in diverse animals, including humans. (wikipedia.org)
  • Thus
  • Thus, protocols to isolate and culture individual organs of interest are essential to provide a method of both visualizing changes in development and allowing novel treatment strategies. (jove.com)
  • Thus, we present a novel method for long-term culture of embryonic hearts. (jove.com)
  • During their development, all anamniote classes pass through a stage which resembles fish, thus indicating their close physiological relationship. (wikipedia.org)
  • genes
  • In males, certain Y chromosome genes, particularly SRY, control development of the male phenotype, including conversion of the early bipotential gonad into testes. (wikipedia.org)