• Amyloid precursor protein 96-110 and beta-amyloid 1-42 elicit developmental anomalies in sea urchin embryos and larvae that are alleviated by neurotransmitter analogs for acetylcholine, serotonin and cannabinoids. (nih.gov)
  • Early developmental gene regulation in Strongylocentrotus purpuratus embryos in response to elevated CO₂ seawater conditions. (ucsd.edu)
  • After fertilization, chicken embryos undergo a series of developmental events in utero for approximately 24 h, including cellularization, the ZGA and layers increase during the cleavage period, and lineage specification and layer reduction during area pellucida formation [ 15 ]. (biomedcentral.com)
  • During the development of the pre-implantation embryo, precise reprogramming progress is a prerequisite for avoiding developmental defects or embryonic lethality, but the underlying molecular mechanisms remain elusive. (bvsalud.org)
  • An early non-mammalian embryo that follows the MORULA stage. (wakehealth.edu)
  • In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN. (centralx.com)
  • Mammalian fertilization begins with the fusion of two specialized gametes, followed by major epigenetic remodeling leading to the formation of a totipotent embryo. (bvsalud.org)
  • For the past few years, unprecedented breakthroughs have been made in mapping the regulatory network of dynamic epigenomes during mammalian early embryo development, taking advantage of multiple advances and innovations in low-input genome-wide chromatin analysis technologies. (bvsalud.org)
  • In the areas of vertebrate development biology and functional genomics, the transparency of the zebrafish embryo during development has allowed researchers to track regulation of gene expression using fluorescent protein genes in real time in living animals. (biogemservice.it)
  • Objective@#The aim of this study was to explore the ototoxicity of toluene in the early development of zebrafish embryos/larvae. (bvsalud.org)
  • Here, structure-function analyses of Gli proteins have been performed using floor plate and neuronal induction assays in frog embryos, as well as induction of alkaline phosphatase (AP) in SHH-responsive mouse C3H10T1/2 (10T1/2) cells. (nih.gov)
  • Immediately following fertilization, the fruit fly embryo undergoes 13 rapid, synchronous, syncytial nuclear division cycles driven by maternal genes and proteins. (ox.ac.uk)
  • Research resources to be shared include genetically modified or mutant organisms, sperm, embryos, protocols for genetic and phenotypic screens, mutagenesis protocols, and genetic and phenotypic data for all mutant strains. (nih.gov)
  • Their name derives from the observation of a hedgehog-like appearance in DROSOPHILA embryos with genetic mutations that block their action. (lookformedical.com)
  • We produced a virtual embryo with about 8000 expressed genes per cell. (nih.gov)
  • Marked epigenetic reprogramming is essential to convert terminally differentiated gametes to totipotent embryos. (zfin.org)
  • While inside the egg, the embryo's abdomen is connected to the yolk sac, which provides the embryo with a food source for growing and developing. (smithsonianmag.com)
  • The scar appears when the embryo detaches from the yolk sac and other membranes, before or as it hatches from its egg. (smithsonianmag.com)
  • 2) The neural crest is a population of multipotent progenitor cells that arise from the neural ectoderm in all vertebrate embryos and form a multitude of derivatives including the peripheral sensory neurons, the enteric nervous system, Schwann cells, pigment cells and parts of the craniofacial skeleton. (reading.ac.uk)
  • Developmentally, in avian, the central nervous system develops from the neural plate, an epithelial sheet that arises from the dorsal ectoderm of the developing embryo (Hallonet et al. (academicjournals.org)
  • This is a review of research that supports a hypothesis regarding early restriction of gene expression in the vertebrate embryo. (duke.edu)
  • The relative ease of obtaining mature adults and embryos makes this animal an ideal model for investigations into early vertebrate evolution. (ox.ac.uk)
  • Zebrafish (Danio rerio) fed vitamin E-deficient diets produce embryos with increased morphologic abnormalities and mortality. (oregonstate.edu)
  • By depleting maternal dnmt1 using oocyte microinjection, we eliminated DNA methylation in early embryos, which died around gastrulation with severe differentiation defects. (zfin.org)
  • The chicken embryo is highly accessible in eggs, easy to manipulate, and robust. (msstate.edu)
  • Moreover, the acquisition of pluripotency in chicken embryos occurs at around EGK.VI to VIII. (biomedcentral.com)
  • The model distinguishes nuclear and cytoplasmic compartments of the embryo and permits exploration of a variety of rules for protein transport between the compartments. (ox.ac.uk)
  • The peripheral cytoplasm (periplasm) of the Drosophila blastoderm embryo is subdivided into apical and basal compartments by a layer of nuclei. (ox.ac.uk)
  • Internal pressure of the embryo and tissue elastic properties help to shape the dorsal surface. (duke.edu)
  • Dynamic interplay of cell fate, polarity and force generation in ascidian embryos. (uchicago.edu)
  • Here, we used single-cell sequencing of precisely staged embryos and devised DistMap, a computational mapping strategy to reconstruct the embryo and to predict spatial gene expression approaching single-cell resolution. (nih.gov)
  • In embryos and COS cells, tagged Gli cDNAs yield C-terminally deleted forms similar to that of Ci. (nih.gov)
  • To determine whether sex-biased expression is present throughout cardiogenesis, we re-analyzed data from two published studies that sampled the transcriptomes of mouse hearts from 8.5 days post-coitum embryos to neonates and adults. (springer.com)
  • A subset of embryos that were exposed to 1.5 nm MES- and TMAT-AuNPs during development from 6 to 120 h post fertilization was raised to adulthood. (oregonstate.edu)
  • This review discusses why the embryo requires vitamin E (VitE) and shows that its lack causes metabolic dysregulation and impacts morphological changes at very early stages in development, which occur prior to when a woman knows she is pregnant. (nih.gov)
  • The establishment of cardiac function in the developing embryo is essential to ensure blood flow and, therefore, growth and survival of the animal. (knaw.nl)
  • Transcript profiling by microarray and quantitative PCR revealed that the majority of zebrafish CYP genes are expressed in embryos, with waves of expression of different sets of genes over the course of development. (nih.gov)
  • In this study, zebrafish embryos were acutely exposed to three gold NPs that possess functional groups with differing surface charge. (oregonstate.edu)
  • After 21 days of incubation, the embryo is fully developed before hatching. (lookformedical.com)
  • Nodal protein was originally discovered in the region of the mouse embryo primitive streak referred to as HENSEN'S NODE. (lookformedical.com)