GlaucomaProduce a transient elevationTransientHyphemaPostoperativeTrabecular meshworkAcuteRetinaInjectionPersistentRetinalPatientsOphthalmicOptic nerve damageAnteriorPosterior chamberTopicalFluidPost-operativePostoperativelyTrabeculoplastyHyphemasMydriaticsChoroidIntracranialCataractsLensConclusionsBlockageProcedureSurgeryTherapyStructuresSuddenOutflowCommonAccumulationOutcomeIncreaseHeadache
Glaucoma20
- glaucoma is the leading cause of unconvertible blindness in the world, and the intraocular pressure (IOP) is still the only target in clinical therapy. (arvojournals.org)
- Intraocular pressure reduction in a pigmentary glaucoma model by Goniotome Ab interno trabeculectomy. (uitm.edu.my)
- Impact of a Glaucoma Severity Index on Results of Trabectome Surgery: Larger Pressure Reduction in More Severe Glaucoma. (uitm.edu.my)
- [ 11 , 12 ] Spontaneous hyphemas due to iris chafing can be seen with anterior chamber intraocular lenses as in uveitis-glaucoma-hyphema (UGH) syndrome or poorly placed posterior chamber intraocular lenses. (medscape.com)
- Late onset lens particle glaucoma as a consequence of spontaneous dislocation of an intraocular lens in pseudoexfoliation syndrome. (medscape.com)
- Pressure within the eye, known as intraocular pressure (IOP), is the only risk factor for glaucoma that can be treated or controlled. (cochrane.org)
- Most of these IOP elevations are transient, but temporarily elevated IOP may cause further optic nerve damage, worsening of glaucoma requiring additional therapy, and permanent vision loss. (cochrane.org)
- Regular high caffeine consumption is associated with a higher risk of developing glaucoma in people with a genetic predisposition to elevated intraocular pressure (IOP), according to a new large-scale study. (nutraingredients.com)
- Keen interest exists in whether caffeine consumption has an intraocular pressure (IOP)-modifying effect, as elevations in ocular tension can increase glaucoma risk. (nutraingredients.com)
- For patients who are unresponsive to pharmacological treatments of glaucoma, an implantable glaucoma drainage devices (GDD) are often used to manage the intraocular pressure. (nature.com)
- Laser iridotomy is a surgical procedure that is performed on the eye to treat angle closure glaucoma, a condition of increased pressure in the front chamber (anterior chamber) that is caused by sudden (acute) or slowly progressive (chronic) blockage of the normal circulation of fluid within the eye. (surgeryencyclopedia.com)
- Elevation of intraocular pressure may be produced by the administration of anticholinergic agents such as Buscopan in patients with undiagnosed and therefore untreated narrow angle glaucoma. (janusinfo.se)
- When the functionality of these cells is impaired, the structure of the trabecular meshwork is perturbed, resulting in intraocular pressure (IOP) elevation, which is the most significant risk factor for primary open-angle glaucoma (POAG) and steroid-induced glaucoma. (uclahealth.org)
- As with most glaucoma surgeries, ECP shares the risk of post-operative IOP elevation. (new-glaucoma-treatments.com)
- Although generally modest and self-limited these post-operative elevations do occasionally require additional medical treatment and (rarely) additional glaucoma surgery to control the IOP. (new-glaucoma-treatments.com)
- Recent research findings provide evidence for Alzheimers disease-related changes in brain diseases, such as normal pressure hydrocephalus and traumatic brain injury, and in glaucoma at the level of the retinal ganglion cells. (eurekaselect.com)
- Overview of Glaucoma Glaucomas are a group of eye disorders characterized by progressive optic nerve damage in which an important part is a relative increase in intraocular pressure (IOP) that can lead to irreversible. (msdmanuals.com)
- Although the role of intraocular pressure (IOP) elevation in glaucoma has been established, the reduction of oxidative stress and inflammation has emerged as a promising target for neuronal tissue-supporting glaucoma management. (arvojournals.org)
- Experimental and clinical studies show that sustained elevation of IOP can cause optic nerve damage similar to primary open-angle glaucoma (POAG), thus providing support for the role of IOP. (medscape.com)
- Current glaucoma therapy is aimed at preventing the development or progression of optic nerve damage and largely relies upon lowering intraocular pressure (IOP). (medscape.com)
Produce a transient elevation1
- Mydriatics may produce a transient elevation of intraocular pressure. (nih.gov)
Transient1
- All mice that received anterior chamber injection of microbeads exhibited transient IOP elevation for approximately 3 weeks. (arvojournals.org)
Hyphema7
- Even a small hyphema due to ocular injury can be a sign of major intraocular trauma with associated damage to vascular and other intraocular tissues. (medscape.com)
- Rapid, marked elevation in intraocular pressure with sudden distortion of intraocular structures produces the dynamic changes responsible for hyphema formation. (medscape.com)
- [ 5 , 6 ] Slow-motion photography has demonstrated deformation of the soccer balls as impact occurs with the orbital rim, thereby imparting direct pressure to the globe, causing the hyphema. (medscape.com)
- Surgical hyphema is a known complication of intraocular surgery and should be managed in a similar manner as traumatic hyphema. (medscape.com)
- Traumatic hyphema may lead to increased intraocular pressure (IOP), peripheral anterior synechiae, atrophy of the optic nerve, staining of the cornea with blood, re-bleeding, and impaired accommodation. (wikipedia.org)
- The most common causes of hyphema are intraocular surgery, blunt trauma, and lacerating trauma. (wikipedia.org)
- The most common events were intraocular pressure elevation, hyphema, and stent blockage. (medscape.com)
Postoperative3
- This lack of reduction in pressure contradicts results from an earlier meta-analysis that showed a reduction in postoperative intraocular pressure when a stent was added to phacoemulsification ( PLoS One . (medscape.com)
- A prospective randomized control trial of 140 eyes from 140 patients, who underwent phacoemulsification, was conducted to compare the efficacy of subtenon corticosteroids injection with corticosteroids eye drops for controlling postoperative intraocular inflammation. (springer.com)
- It is unclear whether perioperative administration of antiglaucoma medications may be helpful in preventing or reducing the occurrence of postoperative IOP elevation. (cochrane.org)
Trabecular meshwork3
- When this occurs, the iris moves away from the trabecular meshwork, and proper drainage of the intraocular fluid is enabled. (surgeryencyclopedia.com)
- An angle closure occurs when drainage of the aqueous fluid through the trabecular meshwork is blocked and the intraocular pressure builds up as a result. (surgeryencyclopedia.com)
- Additionally, we are studying the isolation, culture, and mechanical property characterization of cells residing within the trabecular meshwork, an ocular tissue responsible for intraocular pressure homeostasis. (uclahealth.org)
Acute4
- LTP reduces IOP by 25% to 30% from baseline, but early acute IOP elevation after LTP is a common adverse effect. (cochrane.org)
- It is possible that those with high IOP PRS have a lower reserve to withstand the challenges of intermittent yet frequent acute elevations of IOP caused by caffeine consumption. (nutraingredients.com)
- Removal of aqueous humor is usually considered as a last resort in those cases with acute, severe elevations of intraocular pressure that are unresponsive to medical therapy. (petplace.com)
- The IOP rises quickly when an acute angle attack occurs and within an hour the pressure can be dangerously elevated. (surgeryencyclopedia.com)
Retina2
- However, the combination of retinal breaks, vitreous liquefaction and detachment, traction on the retina (vitreoretinal traction), and intraocular fluid currents associated with movement of liquid vitreous and subretinal fluid can overwhelm these "attachment factors," causing retinal detachment. (aao.org)
- Lowering of the IOP is important because extreme elevations in IOP can damage the retina and the optic nerve permanently. (surgeryencyclopedia.com)
Injection3
- To record intraocular pressure (IOP) at different time intervals after intravitreal injection (IVI) and to correlate the rise in IOP with refractive error and post-injection reflux. (org.pk)
- Rathi R, Patel S, Jain A, Jaiswal K, Nema N. Intraocular Pressure Elevation Following Intra-Vitreal Injection of Bevacizumab, Ranibizumab and Triamcinolone Acetonide: Doi: 10.36351/pjo.v39i3.1626. (org.pk)
- Safety concerns include cataract formation and progression, intraocular pressure elevation, complications related to intravitreal injection, and opportunistic infections secondary to steroid-induced immune suppression. (dovepress.com)
Persistent1
- Patients presenting with persistent pressure elevation may require surgery, trabeculectomy, to create alternative drainage routes for fluid from the eye. (pharmacology2000.com)
Retinal3
- This is due to a combination of retinal breaks, vitreous changes inducing a retinal break and vitreoretinal traction, and intraocular fluid currents. (aao.org)
- Parallel mechanisms autoregulate retinal and cerebral microcirculation to maintain blood flow to meet metabolic demands across a range of perfusion pressures. (springeropen.com)
- Disadvantages include the risk of new retinal breaks, cataract formation and elevation of intraocular pressure [ 6 ]. (biomedcentral.com)
Patients5
- In patients at high risk, monitor blood pressure post treatment. (itbusinessnet.com)
- These are different patients, and you can see a dramatic difference in preop pressure between these comparators. (medscape.com)
- A Seidel test can be helpful in postoperatively assessing wound integrity, particularly in patients with low intraocular pressure (IOP) and a normal or shallow anterior chamber. (aao.org)
- however, an oral carbonic anhydrase inhibitor such as acetazolamide might be used in patients who exhibit continued intraocular pressure elevation despite topical treatment. (pharmacology2000.com)
- In palliative care, patients receiving corticosteroids for symptoms such as fatigue, anorexia, refractory nausea and vomiting or adjuvant analgesia and symptomatic treatment of cord compression or raised intracranial pressure, Dexamethasone phosphate/DEMO may be administered subcutaneously (see section 4.2) as an alternative to the oral route when the latter is unacceptable or no longer feasible. (who.int)
Ophthalmic1
Optic nerve damage1
- In most clinical cases, a painless elevation of IOP occurs, which can lead to progressive optic nerve damage and visual field loss. (medscape.com)
Anterior3
- Elevation of IOP was induced unilaterally in adult wild-type (C57BL/6J) mice and mice deficient for T cell and B cell functions (Rag1-/-) by injecting 15µm polystyrene microbeads to the anterior chamber. (arvojournals.org)
- Resuturing is advised for leaks associated with shallow anterior chambers and low pressures lasting longer than 3 days. (aao.org)
- Normally intraocular fluid flows freely between the anterior and posterior sections of the eye (A). As pressure builds in the eye, this circulation is cut off (B). In laser iridotomy, a special lens is placed on the eye (C). A laser is used to create a hole in part of the iris (D), allowing fluid to flow more normally and intraocular pressure to return to normal (E). (surgeryencyclopedia.com)
Posterior chamber1
- Pressure from the continued secretion of aqueous into the posterior chamber by the ciliary body pushes the peripheral iris anteriorly (causing a forward-bowing iris called iris bombe), closing the angle. (msdmanuals.com)
Topical1
- Topical corticosteroid eye drops, such as 0.1% dexamethasone and 1% prednisolone acetate, are commonly applied for two to four weeks until the intraocular inflammation subsided clinically. (springer.com)
Fluid4
- This fluid is blotted with a sponge as it drains until the intraocular pressure decreases. (petplace.com)
- This new opening helps fluid to leave the eye and lowers intraocular pressure. (pharmacology2000.com)
- The end result of all of these situations is an elevation of the IOP due to a build-up of aqueous fluid in the back part of the eye. (surgeryencyclopedia.com)
- Dex treatment can lead to irregular TM structure and potentially reduce outward flow of intraocular fluid through altering Wnt signaling. (uclahealth.org)
Post-operative1
- The technique is most often used to control severe alterations in intraocular pressure just prior to surgery, or in the immediate post-operative period following laser therapy. (petplace.com)
Postoperatively1
- Despite the advance in technologies, intraocular inflammation in response to tissue injury always occurs postoperatively. (springer.com)
Trabeculoplasty2
- The aim of this Cochrane Review was to find out whether medicines given before, during, or after laser trabeculoplasty (LTP), a surgical method to reduce eye pressure, can prevent increased eye pressure shortly after surgery. (cochrane.org)
- One example, argon laser trabeculoplasty reduces intraocular pressure in some individuals and, if determined efficacious, may be used twice on each eye. (pharmacology2000.com)
Hyphemas1
- Surgery may be necessary for non-resolving hyphemas, or hyphemas that are associated with high pressure that does not respond to medication. (wikipedia.org)
Mydriatics1
- Increased intraocular pressure has been reported following the use of mydriatics. (itbusinessnet.com)
Choroid1
- Melanoma of the uveal tract (iris, ciliary body, and choroid), though rare, is the most common primary intraocular malignancy in adults. (cigna.com)
Intracranial2
- This is a group of diseases that affect central nervous system tissue and are characterized by elevation of intracranial or intraocular pressure and/or local shear stress and strain. (eurekaselect.com)
- As activities or diseases with significant Valsalva effort can generate increased intracranial pressures, we hypothesize that individuals who frequently perform strong Valsalva maneuvers (e.g., long hours of repetitive heavy lifting, sequences of blows during the playing of a wind instrument, forceful and repetitive cough, bearing-down efforts during parturition) may be more susceptible to developing Alzheimers disease. (eurekaselect.com)
Cataracts2
- People receiving the iStent alone receive it for the pressure issue, and people who receive phaco and iStent obviously have cataracts and elevated intraocular pressure. (medscape.com)
- Use of Lotemax for prolonged periods or in high doses may cause serious eye problems (such as high pressure inside the eyes and cataracts). (rxlist.com)
Lens2
- Intraocular inflammatory mass associated with lens-induced uveitis. (medscape.com)
- The only treatment is a surgery to replace the opaque lens with a clear artificial intraocular lens (IOL). (springer.com)
Conclusions1
- Conclusions In V.I.S.I.O.N., after 2 years, there was no evidence of sustained IOP elevation associated with pegaptanib 0.3 mg use. (bmj.com)
Blockage1
- We concluded that elevated intraocular pressure caused apoptotic RGC death through retrograde axoplasmic flow blockage. (nih.gov)
Procedure1
- The procedure allows the medicine to be continuously released into intraocular space. (springer.com)
Surgery1
- People who received medicines to reduce eye pressure as part of their LTP surgery had a lower risk of increased eye pressure after surgery than people who did not receive medicines. (cochrane.org)
Therapy1
- However, oxygen therapy might cause the accumulation of distal bronchial viscous secretions because of positive pressure ventilation mode, and thus increase airway resistance, aggravate systemic hypoxia [15]. (researchgate.net)
Structures1
- Intraocular melanomas can involve two uveal structures simultaneously, such as in ciliochoroidal melanoma. (medscape.com)
Sudden1
- See The Case of the Middle-Aged Woman with Sudden Unilateral Vision Loss , a Critical Images slideshow, to help identify and treat malignant intraocular tumors. (medscape.com)
Outflow2
- The imbalance between the rate of production and the outflow of AH from the eye causes an increased intraocular pressure (IOP), which is a major risk factor that leads to subsequent damage to optic nerve and the loss of eyesight 12 , 13 . (nature.com)
- The effectiveness of adrenergic antagonists in this setting is likely due to reduced outflow tract pressure gradients. (pharmacology2000.com)
Common1
- Uveal melanomas are the most common primary intraocular malignancies and the second most common type of primary malignant melanoma in the body. (medscape.com)
Accumulation1
- Blood accumulation may also cause an elevation of the intraocular pressure. (wikipedia.org)
Outcome2
- The main outcome measured was the development of sustained IOP elevation as defined above. (urosario.edu.co)
- This underlines the importance of not looking only at intraocular pressure" in outcome studies, he told Medscape Medical News . (medscape.com)
Increase2
- High dose results in constriction of blood vessels and increase in blood pressure in addition to the cardiac effects. (medicinenet.com)
- Drinking caffeinated beverages, including black tea, helps increase blood pressure in older people who have low blood pressure after eating. (medlineplus.gov)
Headache1
- It is also used for headache, both low and high blood pressure, preventing Parkinson disease, depression, dementia, stroke, and many other conditions, but there is no good scientific evidence to support many of these uses. (medlineplus.gov)