Elements regulatory sequences nucleic acid. Medical search. Frequent questions

This first comprehensive analysis includes genes and proteins and their relation to human disease, repeated sequences, comparative genome-wide studies of mammalian orthologous chromosomal regions and rearrangement breakpoints, reconstruction of ancestral karyotypes and the events leading to existing species, rates of variation, and lineage-specific and lineage-independent evolutionary events such as expansion of gene families, orthology relations and protein evolution. (nih.gov)
FAE ( Fatty Acid Elongation ) like genes take part in the biosynthesis of VLCFAs, growth regulation, and stress responses, and are further comprised of KCS ( Ketoacyl-CoA synthase ) and ELO ( Elongation Defective Elongase ) sub-gene families. (nature.com)
In this study, 53 KCS genes were identified in B. carinata compared to 32 and 33 KCS genes in B. nigra and B. oleracea respectively, which suggests that polyploidization might has impacted the fatty acid elongation process during Brassica evolution. (nature.com)
The presence of biotic and abiotic stress-related cis-regulatory elements in the promoter region suggests that both KCS and ELO genes might also play their role in stress tolerance. (nature.com)
The current study provides a basis to understand the evolution of both KCS and ELO genes in fatty acid elongation and their role in stress tolerance. (nature.com)
We analyzed respective gene promoters' sequences using in silico methods for identification of transcription binding sites, mainly in the NF-κB- and IRF-coding genes. (biomedcentral.com)
In spite of the importance of this tissue in the quality and production of pollen grains, studies on promoter gene regulation of tapetal expressed genes are very few and there are no reports on specific cis regulatory sequences that control tapetal gene expression. (tamu.edu)
Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases. (lookformedical.com)
Sequences of DNA in the genes that are located between the EXONS. (lookformedical.com)
Compared to the genome of gh-1, the sequence of ϕIBB-PF7A is longer and contains more genes with unassigned function and lacks a few potentially essential and non-essential T7 genes, such as gene1.1, 3.8, and 7. (biomedcentral.com)
Today, phage genome sequencing is commonly performed for classification and characterization purposes and is based on the arrangement of conserved genes and the nucleotide and protein sequence identity [ 5 , 6 ]. (biomedcentral.com)
All these phages, most of which have members of the Enterobacteriaceae as their host, present a highly conserved genome organization and mainly differ at sequence level through the presence or absence of nonessential genes [ 8 ]. (biomedcentral.com)
100.000 cCREs in total), dispersed within the genome and present in cis-regulatory regions of ~81% of human genes, as calculated following gene enrichment analysis. (mdpi.com)
A complex interaction between the cleavage and polyadenylation molecular complex and cis -elements determine the polyadenylation site, which may result in the choice of non-canonical sites, resulting in alternative polyadenylation events, involved in the regulation of more than 80% of the genes expressed in plants. (frontiersin.org)
Concept of gene, Prokaryotes as genetic system, Prokaryotic and eukaryotic chromosomes, methods of gene isolation and identification, Split genes, overlapping genes and pseudo genes, Organization of prokaryotic and eukaryotic genes and genomes including operan, exon, intron, enhancer promoter sequences and other regulatory elements. (nipaers.com)
Furthermore, nucleotide sequences related to the cluster vanHAX are present in this DNA, suggesting that the prolonged use of avoparcin in agriculture led to the uptake of glycopeptide resistance genes by animal commensal bacteria, which were subsequently transferred to humans. (cdc.gov)
Learn to identify homologs of known genes of interest in your newly sequenced genome. (slideshare.net)
Frameshifts and indel errors - Split genes across scaffolds - Highly repetitive sequences To face these challenges, we train annotators in recovering coding sequences in agreement with all available biological evidence. (slideshare.net)
In addition, long-read sequencing of one representative XDR ST235 isolate identified an integron carrying multiple resistance genes (including bla VIM-2), with differences in gene composition and synteny from the P. aeruginosa class 1 integrons described previously. (who.int)

A transposable element (TE, transposon, or jumping gene) is a nucleic acid sequence in DNA that can change its position within a genome, sometimes creating or reversing mutations and altering the cell's genetic identity and genome size. (wikipedia.org)

There are several types: INTERSPERSED REPETITIVE SEQUENCES are copies of transposable elements (DNA TRANSPOSABLE ELEMENTS or RETROELEMENTS) dispersed throughout the genome. (lookformedical.com)

MFMD performance was assessed using ChIP-seq data retrieved from the JASPAR site, promoter sequences extracted from the ABS site, and artificially generated synthetic data. (biomedcentral.com)
Regulatory elements are represented by positional matrices, consensus sequences and individual sites on particular promoter sequences. (vandepeerlab.org)
2002). PlantCARE, a database of plant cis-acting regulatory elements and a portal to tools for in silico analysis of promoter sequences. (vandepeerlab.org)

Noncoding" sequences are not translated into proteins, and nucleic acids with such motifs need not deviate from the typical shape (e.g. the "B-form" DNA double helix). (wikipedia.org)
The plasma protein inhibitors are factor H and C4-binding protein, and the regulatory membrane proteins located on cell surfaces are complement receptors 1 (CR1), decay-accelerating factor (DAF), and membrane cofactor protein (MCP). (justia.com)
Twenty eight (46.7%) of the proteins encoded by this virus exhibit sequence similarity to coliphage T7 proteins while 34 (81.0%) are similar to proteins of Pseudomonas phage gh-1. (biomedcentral.com)
In addition, after transcription, a wide array of RNA-binding proteins interacts with cis -acting elements located mainly in the 3' untranslated region, determining the fate of mRNAs in eukaryotic cells. (frontiersin.org)

Exploring genetic variation in the tomato ( Solanum section Lycopersicon) clade by whole-genome sequencing. (genomeweb.com)
Variant detection sensitivity and biases in whole genome and exome sequencing. (genomeweb.com)
Whole-genome sequence analysis reveals differences in population management and selection of European low-input pig breeds. (genomeweb.com)
A Whole-Genome Analysis Framework for Effective Identification of Pathogenic Regulatory Variants in Mendelian Disease. (lu.se)

Although TEs are selfish genetic elements, many are important in genome function and evolution. (wikipedia.org)
Transposable elements represent one of several types of mobile genetic elements. (wikipedia.org)
Current sequencing technology makes microhaplotypes a powerful new type of genetic marker for forensics. (genomeweb.com)
Fast and cost-effective genetic mapping in apple using next-generation sequencing. (genomeweb.com)
Sequence homology is an indication of the genetic relatedness of different organisms and gene function. (lookformedical.com)
The recent expansion of repeated HERV sequences has offered a framework for genetic and epigenetic innovation. (mdpi.com)
The Centers for Medicare and Medicaid Services (CMS) published information that allows both non Clinical Laboratory Improvement Amendments (CLIA) and CLIA-certified facilities that perform SARS-CoV-2 genetic sequencing on identified specimens to report patient-specific results to state, local, tribal, or territorial public health departments. (cdc.gov)
If the SARS-CoV-2 genetic sequencing result is reported to the ordering provider, reported to the patient, or appears in the patient record - and is intended to be used for the purposes of a person's diagnosis, prevention, treatment, or health assessment -- then the test must be performed in a CLIA-certified laboratory or facility and must comply with all applicable CLIA and FDA regulations. (cdc.gov)
This guidance outlines the process for adding a SARS-CoV-2 genetic sequencing result to an existing electronic laboratory report to provide that information to the state, local, tribal, or territorial health departments. (cdc.gov)
The electronic reporting of the sequencing data should include all the original patient demographic data, along with both the viral test report content and the second ordered test with viral genetic lineage identified. (cdc.gov)

Molecular cloning and transcriptional mapping of the mouse cellular retinoic acid-binding protein gene. (ulaval.ca)
Efficient initiation of synthesis by RNA polymerase II requires a compact element centered ~50 base pairs upstream of the transcriptional start site. (cshl.edu)
The availability of multiple PAS in the same 3' regulatory region enables the inclusion or exclusion of 3' untranslated region (3'UTR) sequences, resulting in transcripts that may differ in particularities involving post-transcriptional processes such as stability, transport and translation ( Mayr, 2016 ), and even protein localization ( Berkovits and Mayr, 2015 ). (frontiersin.org)
However, decoding functional RNA-regulatory features remains a limitation to understanding post-transcriptional regulation in vivo. (nih.gov)

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. (lookformedical.com)
Nucleotide sequences, usually upstream, which are recognized by specific regulatory transcription factors, thereby causing gene response to various regulatory agents. (lookformedical.com)

This was gradually expanded into various methods in bioinformatics, in particular for sequence analysis and protein structure prediction. (ntnu.edu)
The research group has established rigorous methods for benchmarking methods for motif discovery (BMC Bioinformatics 2007, 2008) and ChIP-seq data analysis (Nucleic Acids Res 2011). (ntnu.edu)

further explanation needed] Transposable elements make up a large fraction of the genome and are responsible for much of the mass of DNA in a eukaryotic cell. (wikipedia.org)
DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom. (lookformedical.com)

Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity. (genomeweb.com)

Very long-chain fatty acids (VLCFAs) possess more than twenty carbon atoms and are the major components of seed storage oil, wax, and lipids. (nature.com)
Many long chain fatty acids have been classified as being Omega 3 and have been shown to provide several health benefits, including heart health. (patentsencyclopedia.com)

Targeted chromatin capture (T2C): a novel high resolution high throughput method to detect genomic interactions and regulatory elements. (genomeweb.com)
Journal Article Nucleic Acids Res · August 20, 2021 Chromatin is a tightly packaged structure of DNA and protein within the nucleus of a cell. (duke.edu)
Journal Article Genome Res · June 2021 Though the sequence of the genome within each eukaryotic cell is essentially fixed, it exists within a complex and changing chromatin state. (duke.edu)
Journal Article · June 29, 2020 AbstractThough the sequence of the genome within each eukaryotic cell is essentially fixed, it exists within a complex and changing chromatin state. (duke.edu)

We employed conditional translating ribosome affinity purification (TRAP) followed by RNA sequencing (TRAP-seq) for transcriptome profiling of DA neurons in transgenic Drosophila lines expressing human PARIS wild type (WT) or mutant (C571A). (nature.com)
Isolation and purification of nucleic acids. (nipaers.com)
Based on the knowledge and tools developed while identifying and characterizing new viruses and comparisons to previously-characterized viruses, new virus-specific and broad spectrum polyclonal and/or monoclonal antibody reagents, purification protocols, nucleic acid hybridization probes, PCR primers, isothermal amplification methods, and improved associated protocols will be developed. (usda.gov)

TERMINAL REPEAT SEQUENCES flank both ends of another sequence, for example, the long terminal repeats (LTRs) on RETROVIRUSES. (lookformedical.com)

Human endogenous retroviruses (HERVs) are a family of endogenous retroviruses that comprise the ~8.93% of the human genome sequence, with a high proportion being human specific. (mdpi.com)
Non-natural oligonucleotides are valuable probes of biological systems, as they can convey synthetic control of endogenous nucleic acids with high sequence specificity. (cdc.gov)

2002). The PlantCARE database and tools for in silico search of plant cis-acting regulatory elements. (vandepeerlab.org)
In silico 3-dimensional structure predictions for mutated OmpK36 porin in Klebsiella pneumoniae sequence type 512 strain 0296 in study of K . pneumoniae genotypic evolution during ceftazidime/avibactam, meropenem/vaborbactam, and cefiderocol treatment, Italy. (cdc.gov)

Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. (lookformedical.com)
Highly repeated sequences, 100-300 bases long, which contain RNA polymerase III promoters. (lookformedical.com)

Nucleic acids hybridization: Southern, northern and western blotting hybridization. (nipaers.com)

Fatty acids of this group can be found abundantly in the form of suberins, sphingolipids, leaf cuticles, pollen epidermis, and cork cells. (nature.com)
In addition to improved health benefits the current invention provides food rich in Omega-3 fatty acids that have enhanced storage and/or shelf life characteristics. (patentsencyclopedia.com)
2% SDA and at most about 40% LA based on the total weight of fatty acids or derivatives thereof in the composition, and wherein said transgenic soybean oil comprises at least about 400 ppm tocopherols. (patentsencyclopedia.com)
121. The food ingredient of claim 118 wherein said transgenic soybean oil further comprises of at least 10% SDA and at most about 35% LA based on the total weight of fatty acids or derivatives thereof in the composition. (patentsencyclopedia.com)

AAV type 2 wild-type and vector-mediated genomic integration profiles in human diploid fibroblasts analyzed by 3rd generation PacBio DNA sequencing. (genomeweb.com)
In the study of genomic cis -regulatory elements, generation of mice featuring transgenic reporters or cis -regulatory element knockout remains the standard approach. (mdpi.com)

According to the methods, a mixture of lipids containing a protonatable or deprotonatable lipid, for example an amino lipid and a lipid such as a PEG- or Polyamide oligomer-modified lipid is combined with a buffered aqueous solution of a charged therapeutic agent, for example polyanionic nucleic acids, to produce particles in which the therapeutic agent is encapsulated in a lipid vesicle. (justia.com)

and although less conserved, plants also have polyadenylation signals: far upstream element (FUE), near upstream element (NUE) and the cleavage element (CE) ( Xing and Li, 2011 ). (frontiersin.org)

Thus, analysis of TCR CDR3 sequences has provided a useful means to study clonal expansions, repertoire breadth, and other properties such as CDR3 length polymorphisms, V(D)J gene usage, and sequence specificity of the T cell response. (biomedcentral.com)

The BN rat sequence is the third complete mammalian genome to be deciphered, and three-way comparisons with the human and mouse genomes resolve details of mammalian evolution. (nih.gov)
Next generation sequencing (NGS) of nucleic acid extracts from plants infected with unknown viruses is expected to yield information about the genomes of previously uncharacterized viruses without any background information on what viruses might be infecting the plant. (usda.gov)

We also show that sequence elements that direct 3'-end formation of the A. lumbricoides trans- spliced leader RNA function when RNA synthesis is initiated from the U1 promoter. (cshl.edu)

Retrotransposons are commonly grouped into three main orders: Retrotransposons, with long terminal repeats (LTRs), which encode reverse transcriptase, similar to retroviruses Retroposons, long interspersed nuclear elements (LINEs, LINE-1s, or L1s), which encode reverse transcriptase but lack LTRs, and are transcribed by RNA polymerase II Short interspersed nuclear elements (SINEs) do not encode reverse transcriptase and are transcribed by RNA polymerase III Retroviruses can also be considered TEs. (wikipedia.org)

In biology, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and usually assumed to be related to biological function of the macromolecule. (wikipedia.org)

These elements may be found in both promoter and enhancer regions. (lookformedical.com)
The 3' regulatory regions have a great diversity of cis -regulatory elements directly involved in polyadenylation, stability, transport and mRNA translation, essential to achieve the desired levels of gene expression. (frontiersin.org)
Although a small number of 3' regulatory regions have been identified and validated so far, many studies have shown that plant 3' regulatory regions have a higher potential to regulate gene expression in plants compared to widely used 3' regulatory regions, such as NOS and OCS from Agrobacterium tumefaciens and 35S from cauliflower mosaic virus. (frontiersin.org)
In this review, we discuss the role of 3' regulatory regions in gene expression, and the superior potential that plant 3' regulatory regions have compared to NOS, OCS and 35S 3' regulatory regions. (frontiersin.org)
The non-coding regions downstream of coding sequences (CDS) is usually termed terminators. (frontiersin.org)
SP1 and GATA3) and HDAC2-GATA1 regulatory networks on rescued regions in K562 cell line. (biomedcentral.com)
4462 functional sequence variations in regulatory DNA regions in training dataset F1 and 1116 functional SNVs in test datasets F2. (lu.se)

Primers 16S 440F and 16S 1491R (Table) were ing of glycopeptide antimicrobial agents to their designed to amplify partial 16S rDNA sequences. (cdc.gov)

Outside of gene exons, there exist regulatory sequence motifs and motifs within the "junk", such as satellite DNA. (wikipedia.org)
Within a sequence or database of sequences, researchers search and find motifs using computer-based techniques of sequence analysis, such as BLAST. (wikipedia.org)
We have developed an approach for detecting motifs in biopolymers sequences. (biomedcentral.com)
Sequence motifs are small sequences capable of acting as binding sites for a particular transcription factor [ 1 ]. (biomedcentral.com)
We designed and executed a massively parallel reporter assay (MPRA) to investigate the effect of transcription factor binding motifs and local sequence context on p53-bound CRE activity. (whiterose.ac.uk)
Our data indicate that p53-bound CREs are both positively and negatively affected by alterations in local sequence context and changes to co-regulatory TF motifs. (whiterose.ac.uk)

MToolBox: a highly automated pipeline for heteroplasmy annotation and prioritization analysis of human mitochondrial variants in high-throughput sequencing. (genomeweb.com)

This invention relates to compositions comprising a combination of a lipid and a therapeutic agent, particularly to lipid-nucleic acid compositions, for in vivo therapeutic use. (justia.com)
Here, we developed RNA-element selection assay (RESA), a method that selects RNA elements on the basis of their activity in vivo and uses high-throughput sequencing to provide a quantitative measurement of their regulatory functions at near-nucleotide resolution. (nih.gov)
RESA provides a sensitive and quantitative measure of microRNA activity in vivo and also identifies novel regulatory sequences. (nih.gov)

See also consensus sequence. (wikipedia.org)
Usually, however, the first letter is I, and both [RK] choices resolve to R. Since the last choice is so wide, the pattern IQxxxRGxxxR is sometimes equated with the IQ motif itself, but a more accurate description would be a consensus sequence for the IQ motif. (wikipedia.org)
Exact approaches usually use the consensus sequence for motif representation, employing some mathematical optimization as the search model. (biomedcentral.com)
The most important of these, although not capable of driving hypoxic induction in isolation, had the consensus of a hypoxia-inducible factor 1 (HIF-1) site, and cross-competed for the binding of HIF-1 with functionally active Epo and phosphoglycerate kinase-1 sequences. (ox.ac.uk)
I analyzed the presence of HERV sequences on consensus cis-regulatory elements (cCREs) from ENCODE data. (mdpi.com)

Methods for the preparation of a lipid-nucleic acid composition are provided. (justia.com)
Additionally, the invention provides methods of making the compositions, as well as methods of introducing the nucleic acids into cells using the compositions and treating disease conditions. (justia.com)
Improved detection and differentiation methods for these pathogens will enable state and federal regulatory officials to make timely and appropriate recommendations in safeguarding the movement of horticultural and agricultural products into the United States. (usda.gov)
Laboratories should only report results to patients or providers when the methods used to perform the sequencing have met CLIA requirements for establishing performance specifications and have received Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA). (cdc.gov)

These transcripts are almost evenly divided between those arising from enhancer-associated (elncRNA) or promoter-associated (plncRNA) elements. (biomedcentral.com)
Mendelian regulatory variations including 42 enhancer, 142 promoter, 153 5' UTR, 43 3' UTR, 65 RNA gene, 3 imprinting control region, and 5 microRNA gene variations. (lu.se)

PlantCARE is a database of plant cis-acting regulatory elements, enhancers and repressors. (vandepeerlab.org)

120. The food ingredient of claim 118 wherein the transgenic soybean oil comprises at least one stabilizing agent selected from the group consisting of citric acid, t-butyl hydroquinone, ascorbyl palmitate, propyl gallate, and combinations thereof. (patentsencyclopedia.com)

Isolated nucleic acid molecules encoding the peptides are also disclosed. (justia.com)

Immune response monoclonal and polyclonal antibodies and ELISA, DNA sequencing. (nipaers.com)

Nucleic Acids Research, 48 (8). (whiterose.ac.uk)
Nucleic Acids Research, 45(5), 2307-2317. (lu.se)

Laboratories and facilities that have SARS-CoV-2 positive specimens and intend to report SARS-CoV-2 lineages, including variants, should upload sequence data to a public database (e.g. (cdc.gov)
27558 Mendelian disease regulatory variants from OMIM and ClinVar, 20963 complex disease regulatory variants from VarDi and NHGRI GWAS Catalog and 43364 recurrent cancer somatic variations. (lu.se)
Disease-associated variants in different categories of disease located in distinct regulatory elements. (lu.se)
Quantifying deleterious effects of regulatory variants. (lu.se)

To expand the knowledge about interactions between TFs and TFBSs, three biological features (sequence feature, structure feature, and evolution feature) were utilized to build TFBS identification models for studying binding preference between TFs and their DNA targets in mammals. (biomedcentral.com)

1) Sequence feature, which is the sequence similarity of DNA segments to a position weight matrix (PWM). (biomedcentral.com)

In the human genome, L1 and Alu elements are two examples. (wikipedia.org)

Therapeutic oligonucleotides, such as antisense oligonucleotides or ribozymes, are short segments of DNA that have been designed to hybridize to a sequence on a specific mRNA. (justia.com)
The polyadenylation site (PAS), point from which the pre-mRNA is cleaved and polyadenylated, is defined by surrounding cis- elements ( Tian and Manley, 2016 ). (frontiersin.org)
We implemented RESA to identify sequence elements modulating mRNA stability during zebrafish embryogenesis. (nih.gov)

We report here the genome sequence of the Brown Norway (BN) rat strain. (nih.gov)
This work describes the complete genome sequence of this phage. (biomedcentral.com)
This work focuses on the determination of the complete genome sequence of the P. fluorescens phage ϕIBB-PF7A. (biomedcentral.com)

Stepwise threshold clustering: a new method for genotyping MHC loci using next-generation sequencing technology. (genomeweb.com)
Recently, next-generation sequencing (NGS) of the T cell receptor (TCR) β loci has emerged as a sensitive way to measure the T cell repertoire. (biomedcentral.com)
Región reguladora que fue identificada por primera vez en el locus de la globina beta humana pero que se halló posteriormente en otros loci. (bvsalud.org)
A regulatory region first identified in the human beta-globin locus but subsequently found in other loci. (bvsalud.org)

The Marmoset Genome Sequencing and Analysis Consortium. (genomeweb.com)
To uncover specific sequence requirements within regulatory elements, we developed a bisulfite-mediated nucleotide-conversion strategy for large-scale mutational analysis (RESA-bisulfite). (nih.gov)

A cis regulatory element in the TAPNAC promoter directs tapetal gene expression. (tamu.edu)
To understand the organization of cis-acting sequences that are responsible for oxygen-regulated gene expression, we have studied the 5' flanking region of the mouse gene encoding the hypoxically inducible enzyme lactate dehydrogenase A (LDH). (ox.ac.uk)
Although the role of p53 as a strong trans-activator of gene expression is well known, the co-regulatory factors and local sequences acting at p53-bound CREs are comparatively understudied. (whiterose.ac.uk)

The third domain had the motif of a cAMP response element (CRE). (ox.ac.uk)
For the first time, minor differences within the sequence motif known as the VRN-box of VRN1 were correlated with wheat growth habit. (biomedcentral.com)

2 − 6 These nuclease-resistant polymers persist in live organisms for days and are typically designed to recognize 25-base sequences that span intron-exon junctions or translational start sites. (cdc.gov)

Assessing the impact of water treatment on bacterial biofilms in drinking water distribution systems using high-throughput DNA sequencing. (genomeweb.com)

The region of DNA which borders the 3' end of a transcription unit and where a variety of regulatory sequences are located. (lookformedical.com)

Understanding the Promises and Hurdles of Metagenomic Next-Generation Sequencing as a Diagnostic Tool for Infectious Diseases. (cdc.gov)
225 Functional regulatory SNVs in monogenic and complex diseases and 241910 SNVs from dbSNP as a negative control dataset. (lu.se)

The main problem here is the reliability of evolutionary reconstructions based on sequence data. (icr.org)
CDC requests laboratories that are sequencing SARS-CoV-2 positive specimens to report those data to state, local, tribal, or territorial public health departments. (cdc.gov)
Any sequencing data can be reported to public health. (cdc.gov)

Unlocking the secondary gene-pool of barley with next-generation sequencing. (genomeweb.com)
Long-range PCR in next-generation sequencing: comparison of six enzymes and evaluation on the MiSeq sequencer. (genomeweb.com)

In the last few years, a large number of T7-like phages have been sequenced most of which have been gathered in a new viral subfamily within the family Podoviridae . (biomedcentral.com)
SARS-CoV-2 sequencing results should be reported as a follow-up to the original positive viral test result and reported to the same public health department. (cdc.gov)
Hypothesis: RNA and DNA Viral Sequence Integration into the Mammalian Host Genome Supports Long-Term B Cell and T Cell Adaptive Immunity. (cdc.gov)

Originally discovered as a chief regulatory protein of glucose and lipid metabolism and cell differentiation, the peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated transcription factor of the nuclear hormone receptor superfamily 8 . (nature.com)
Once the embryo is formed and cell division arrests, the seed enters the maturation phase characterised by an increase of the levels of ABA (abscisic acid) required for the establishment and maintenance of dormancy upon completion of maturation. (encyclopedia.pub)
Because allelic exclusion leads to the expression of only one TCR chain in mature T cells [ 29 ], each unique CDR3 sequence is a proxy for T cell clonotype. (biomedcentral.com)
We envisioned that enzyme-activatable cMOs could overcome these limitations, as the triggering enzymes could be expressed in individual cell populations using cis regulatory elements. (cdc.gov)
Treg, regulatory T cell. (cdc.gov)

Anatomy10

Organisms18

Diseases1

Chemicals and Drugs83

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Phenomena and Processes117

Disciplines and Occupations2

Technology, Industry, Agriculture2

Information Science11

Health Care2

Genes19

Jumping gene1

Repetitive Sequences1

Promoter sequences3

Proteins4

Whole genome4

Genetic10

Transcriptional4

Nucleotide sequences2

Bioinformatics2

Transposable Elements2

Epigenetic1

Long-chain2

Chromatin4

Purification3

TERMINAL REPEAT SEQUENCES1

Endogenous2

Silico2

Promoters2

Hybridization1

Fatty4

Genomic2

Lipids1

Upstream1

Specificity1

Genomes2

Synthesis1

Polymerase1

Amino-acid seq1

Regions7

Primers1

Motifs6

Mitochondrial1

Vivo3

Consensus5

Methods4

Enhancer2

Repressors1

Citric1

Peptides1

Monoclonal1

Research2

Variants4

Biological1

Similarity1

Human genome1

MRNA3

Genome sequence3

Loci4

Analysis2

Gene expression3

Motif2

Exon1

Bacterial1

Transcription unit1

Diseases2

Data3

Next generation2

Viral3

Cell5