DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesHealth Care
PravastatinHydroxymethylglutaryl-CoA Reductase InhibitorsAnticholesteremic AgentsHeptanoic AcidsHypercholesterolemiaSimvastatinPyrrolesTreatment OutcomeFosinoprilDouble-Blind MethodLovastatinCholesterol, LDLCholesterolFluorobenzenesFatty Acids, MonounsaturatedPhysiological ProcessesMevalonic AcidDose-Response Relationship, DrugLipidsDrug InteractionsOrganic Anion TransportersDrug Therapy, Combination
AtorvastatinSimvastatinStatinsMonotherapy for the treatmentLovastatinEvaluated the efficacy and tolerabilitySodiumVersus PravastatinCoronary heart dTolerabilityFenofibrateHyperlipidaemiaSafetyLIPIDEvaluateTabletsTherapyAmlodipineCholesterolPatientsPreventionYeast riceOutcomesSupplementsClinicalEffectivenessAcuteStudyPooled dataDosageInteractionAdverse effectsTreatmentSymptomsIncreasesRelatively lowEffectExtentCombinationTrialsRandomized contrDouble-blindHigherEventsResultsImproveLevelsResources
Atorvastatin4
Simvastatin2
  • Candidate drugs included two types of hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitors, simvastatin and pravastatin, because of their importance at reducing the health expenditure for hyperlipidemia. (bvsalud.org)
  • A total of 118 patients in the simvastatin study and 43 patients in the pravastatin study were candidates for the present study. (bvsalud.org)
Statins5
  • Most previous observational studies have been limited by a small number of cases, short follow-up period, unverified self-reports on use and consistency of statins therapy, and no assessment of statins efficacy. (cdc.gov)
  • In 2 examples (the development of anti-platelet agents and statins), we show that enhanced efficacy failed to achieve the health gains that would have occurred by delivering older agents to all eligible patients. (annfammed.org)
  • The efficacy of statins in the prevention of CHD has been shown in various randomised trials (1-5). (gpnotebook.com)
  • In conclusion, red yeast rice was tolerated as well as pravastatin and achieved a comparable reduction of low-density lipoprotein cholesterol in a population previously intolerant to statins. (jarretmorrow.com)
  • The results of the present study demonstrated that the antitumor efficacy of ATST could be enhanced at a relatively low dosage through the synergistic action with PT, which suggested the potential interaction of statins with other compounds in the food matrix. (epiphanyasd.com)
Monotherapy for the treatment1
  • These three trials provided good evidence for the efficacy and safety of gabapentin monotherapy for the treatment of partial-onset seizures. (keywen.com)
Lovastatin1
Evaluated the efficacy and tolerability1
  • We evaluated the efficacy and tolerability of zonisamide for migraine prophylaxis in refractory patients. (keywen.com)
Sodium11
  • These highlights do not include all the information needed to use PRAVASTATIN SODIUM TABLETS safely and effectively. (nih.gov)
  • See full prescribing information for PRAVASTATIN SODIUM TABLETS. (nih.gov)
  • For patients that require a high-intensity statin or are unable to achieve their LDL-C goal receiving pravastatin sodium tablets 80 mg daily, prescribe alternative LDL-C-lowering treatment ( 2.1 ). (nih.gov)
  • Assess LDL-C when clinically appropriate, as early as 4 weeks after initiating pravastatin sodium tablets, and adjust the dosage if necessary ( 2.1 ). (nih.gov)
  • Adults: recommended starting dosage is pravastatin sodium tablets 40 mg to 80 mg once daily. (nih.gov)
  • Severe renal impairment: recommended starting dosage is pravastatin sodium 10 mg once daily. (nih.gov)
  • Use another pravastatin sodium product to initiate dosing. (nih.gov)
  • Recommended maximum pravastatin sodium tablets dosage is 40mg once daily. (nih.gov)
  • Tablets: 80 mg of pravastatin sodium. (nih.gov)
  • Tablets: 10 mg, 20 mg, and 40 mg of pravastatin sodium. (nih.gov)
  • Drug2 (rxcui = 904481, name = pravastatin sodium 80 MG Oral Tablet, tty = SCD). (druginteractionchecker.com)
Versus Pravastatin1
  • Tolerability of red yeast rice (2,400 mg twice daily) versus pravastatin (20 mg twice daily) in patients with previous statin intolerance. (jarretmorrow.com)
Coronary heart d1
Tolerability4
  • In addition, it was found equivalent to controlled release carbamazepine as first-line therapy for partial-onset seizures, both in efficacy and tolerability. (keywen.com)
  • The efficacy and tolerability of rizatriptan for the acute treatment of migraine have thus been well established. (keywen.com)
  • Domperidone in the management of symptoms of diabetic gastroparesis: efficacy, tolerability, and quality-of-life outcomes in a multicenter controlled trial. (keywen.com)
  • In another recent study published in the Amercian Journal of Cardiology (Halbert et al, 2010), the study authors compared the efficacy and tolerability of Red yeast rice (2400 mg twice daily) to Prevastatin (20 mg twice daily) for 12 weeks. (jarretmorrow.com)
Fenofibrate2
Hyperlipidaemia1
Safety14
  • Efficacy was quantified as the percentage change in seizure frequency, and safety was assessed by the frequency and types of adverse events. (keywen.com)
  • Efficacy and safety of vagus nerve stimulation in patients with complex partial seizures. (keywen.com)
  • Extensive testing for efficacy (effectiveness) and safety is carried out before the vaccine is licensed. (keywen.com)
  • Adjunctive lacosamide for partial-onset seizures: Efficacy and safety results from a randomized controlled trial. (keywen.com)
  • The purpose of the study is to assess the safety and efficacy of MK0974 in acute treatment of multiple migraine attacks with or without aura. (keywen.com)
  • Efavirenz is not recommended for use in patients younger than 3 years and weighing less than 10 kg due to a lack of data on safety and efficacy. (who.int)
  • Evaluation of efficacy and safety]. (bvsalud.org)
  • Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. (uc.edu)
  • We retrospectively evaluated the efficacy (total cholesterol, triglyceride, low-density lipoprotein and high-density lipoprotein levels), safety (biochemical parameters), and medication adherence based on patient data. (bvsalud.org)
  • Effect of Berberine on Metabolic Syndrome, Efficacy and Safety in Combination With Antiretroviral Therapy in PLWH. (go.jp)
  • The Obstetric and Pediatric Pharmacology and Therapeutics Branch (OPPTB), formerly the Obstetric and Pediatric Pharmacology Branch (OPPB), promotes basic, translational, and clinical research to improve the safety and efficacy of therapeutics, primarily pharmaceuticals and to ensure centralization and coordination of research, clinical trials, and drug development activities for obstetric and pediatric populations. (utmb.edu)
  • Over the past year, there have been several research studies on the efficacy and safety for Chinese red yeast rice supplements for lowering cholesterol levels particularly in patients who cannot tolerate statin-type medication. (jarretmorrow.com)
  • While randomized controlled trials provide useful information about drug safety and efficacy, they do not always reflect the observed results in the real world. (e-enm.org)
  • The prospective, observational, non-comparative trial in South Korea was designed to evaluate the efficacy and safety of pitavastatin in clinical practice in 28,343 patients. (e-enm.org)
LIPID3
  • 5 Reductions associated with cinnamon in LDL cholesterol and triglyceride levels-9.4 mg/dL and 29.6 mg/dL, respectively-are also less than we see from the common lipid-lowering drugs, pravastatin and gemfibrozil, which reduce LDL cholesterol and triglyceride levels by approximately 50 mg/dL (26%) and 50 mg/dL (31%), respectively. (naturalmedicinejournal.com)
  • 8. Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) Study Group. (med-sovet.pro)
  • The various genotypes of the ApoA1 G75A SNP influence the efficacy of lipid regulation by pravastatin and policosanol in patients with hyperlipidemia. (superfoodly.com)
Evaluate2
  • So the objective of this study is to evaluate the efficacy of imipramine, a tricyclic antidepressant, in treatment of functional dyspepsia. (keywen.com)
  • The aim of this study was to evaluate the efficacy of amitriptyline in children with pain-predominant functional gastrointestinal disorders. (keywen.com)
Tablets1
Therapy2
  • Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled trials. (keywen.com)
  • Pravastatin therapy and the risk of stroke. (med-sovet.pro)
Amlodipine1
  • His medical history included arterial hypertension controlled with amlodipine and dyslipidemia and coronary artery disease treated with pravastatin and aspirin. (cdc.gov)
Cholesterol2
Patients6
  • Temporarily discontinue pravastatin in patients experiencing an acute or serious condition at high risk of developing renal failure secondary to rhabdomyolysis. (nih.gov)
  • Inform patients of the risk of myopathy and rhabdomyolysis when starting or increasing pravastatin dosage. (nih.gov)
  • Most of these patients were using the only effective drug then available, bromide, which had terrible side effects and limited efficacy. (keywen.com)
  • Clinical trial on the efficacy of a new symbiotic formulation, Flortec, in patients with irritable bowel syndrome: a multicenter, randomized study. (keywen.com)
  • Independent of the efficacy or effectiveness of interventions, fidelity is the extent to which the system provides patients the precise interventions they need, delivered properly, precisely when they need them. (annfammed.org)
  • He didnt give your body what discount Ezetimibe No Prescription animal fats, obesity, chest pains, especially saturated fats, unsaturated fats and neck flushing, a bowl of energy back to a year old we do Experts say that eventually reduce the U. patients with pravastatin for six supplements contain and Zocor. (parallaxbusinessservices.com)
Prevention2
  • Estimates of vaccine efficacy (i.e., prevention of illness among vaccinated persons enrolled in controlled clinical trials) and vaccine effectiveness (i.e., prevention of illness in vaccinated populations) of influenza vaccines depend on many factors, including the age and immunocompetence of the vaccine recipient, the degree of similarity between the viruses in the vaccine and those in circulation, study design, diagnostic testing measures, and the outcome being measured. (cdc.gov)
  • Studies of influenza vaccine efficacy and effectiveness have used a variety of outcome measures, including the prevention of ILI, medically attended acute respiratory illness (MAARI), LCI, P&I-associated hospitalizations or deaths, and prevention of seroconversion to circulating influenza virus strains. (cdc.gov)
Yeast rice1
  • The incidence of withdrawal from medication owing to myalgia (muscle pain) was 5% (1 of 21) in the red yeast rice group and 9% (2 of 22) in the pravastatin group (p = 0.99). (jarretmorrow.com)
Outcomes3
  • 2 Second, the interventions that Americans do receive have limited efficacy in improving outcomes. (annfammed.org)
  • Efficacy or effectiveness estimates for more specific outcomes such as LCI typically are higher than for less specific outcomes such as MAARI because the causes of MAARI include infections with other pathogens that influenza vaccination would not be expected to prevent ( 105 ). (cdc.gov)
  • For studies assessing laboratory-confirmed outcomes, estimates of vaccine efficacy and effectiveness also might be affected by the specificity of the diagnostic tests used. (cdc.gov)
Supplements2
  • In 2017, a Chinese trial was published where each person received either policosanol supplements or pravastatin. (superfoodly.com)
  • com Five Supplements On top of oxygen through the standard prescribed to which is limited efficacy ofwhich spikes your life, although data rights that the most cases - particularly attractive choice, vegetables 24 hours later utilize other medications, such as another medication Your first it is also make your doctor. (parallaxbusinessservices.com)
Clinical1
  • The purpose of this study is to compare the clinical efficacy between original drugs and generic products. (bvsalud.org)
Effectiveness4
  • Effectiveness and efficacy of zinc for the treatment of acute diarrhea in young children. (keywen.com)
  • Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review. (keywen.com)
  • The second strategy to alleviate disease is to enhance the efficacy (and effectiveness) of interventions. (annfammed.org)
  • The effort to improve efficacy and effectiveness involves the development of new agents and products in university-based and private industrial laboratories, and the dissemination of these products through licensing, advertising, and other channels. (annfammed.org)
Acute3
  • Acute blood flow changes and efficacy of vagus nerve stimulation in partial epilepsy. (keywen.com)
  • The efficacy of VIOXX in the acute treatment of migraine headaches was demonstrated in two double-blind, placebo-controlled, outpatient trials. (keywen.com)
  • Efficacy of naturopathic extracts in the management of ear pain associated with acute otitis media. (jptcp.com)
Study3
  • Efficacy was demonstrated in both studies at a dose of 200 mcg twice daily and in one study at a dose of 200 mcg once a day (see table below). (keywen.com)
  • A preliminary study on the efficacy of sertraline and imipramine on anger attacks in atypical depression and dysthymia. (keywen.com)
  • This study showed no significant differences in efficacy or side effects between amitriptyline and gabapentin. (keywen.com)
Pooled data1
  • The averages displayed are based on pooled data from 2 placebo-controlled, outpatient trials providing evidence of efficacy (Studies 1 and 2). (keywen.com)
Dosage1
  • Risk factors include age 65 years or greater, uncontrolled hypothyroidism, renal impairment, concomitant use with certain other drugs, and higher pravastatin dosage. (nih.gov)
Interaction1
Adverse effects1
  • However, these agents have not achieved worldwide use because of limited efficacy or unacceptable adverse effects. (keywen.com)
Treatment2
  • The primary efficacy analysis was the number of migraine attacks during the last 4 weeks of treatment. (keywen.com)
  • The primary efficacy parameter was the number of migraine attacks during the last 28 days of the treatment period compared with baseline. (keywen.com)
Symptoms1
  • 16. Grube B, Walper A, Wheatley D. St. John's Wort extract: efficacy for menopausal symptoms of psychological origin. (jptcp.com)
Increases1
  • Using mathematical arguments and a nomogram, we demonstrate that technological advances must yield dramatic, often unrealistic increases in efficacy to do more good than could be accomplished by improving fidelity. (annfammed.org)
Relatively low1
  • For pravastatin, however, the risk was assessed based on its relatively low fat solubility (and thus the ability to accumulate in biota) in relation to its potency in humans. (janusinfo.se)
Effect1
  • Efficacy is the capacity to produce an effect. (keywen.com)
Extent1
  • We must take our choice between a limited extent and a limited efficacy, or rather between a limited atonement and an atonement without efficacy. (keywen.com)
Combination1
Trials1
  • Randomized controlled trials that measure LCI virus infections (by viral culture or reverse transcription polymerase chain reaction [RT-PCR]) as the outcome provide the best and most persuasive evidence of vaccine efficacy, but such data are not available for all populations. (cdc.gov)
Randomized contr1
  • Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial. (keywen.com)
Double-blind1
  • A prospective, randomized, placebo controlled, double-blind design was used to test the efficacy of imipramine and fluoxetine. (keywen.com)
Higher1
Events1
  • Habituation (ie, the loss of efficacy over time) or new adverse events that result from vagus nerve stimulation would limit its use. (keywen.com)
Results1
  • The results of our trial will be helpful to supply the evidence on the efficacy of acupuncture for migraine prophylaxis in China. (keywen.com)
Improve1
  • Society's huge investment in technological innovations that only modestly improve efficacy, by consuming resources needed for improved delivery of care, may cost more lives than it saves. (annfammed.org)
Levels1
  • Discontinue pravastatin if markedly elevated CK levels occur or myopathy is diagnosed or suspected. (nih.gov)
Resources1
  • An objective observer would concede that the United States devotes most of its resources to the second aim, the enhancement of efficacy. (annfammed.org)