ExocytosisSecretory VesiclesChromaffin CellsCytoplasmic GranulesSynaptotagminsSNARE ProteinsCalciumSynaptic VesiclesElectric CapacitanceVesicular Transport ProteinsSynaptosomal-Associated Protein 25Weibel-Palade Bodiesrab3A GTP-Binding ProteinQa-SNARE ProteinsR-SNARE ProteinsMembrane FusionSyntaxin 1Acrosomerab3 GTP-Binding ProteinsPC12 CellsSynaptotagmin ICell MembraneMunc18 ProteinsPyridinium CompoundsCells, CulturedNerve Tissue Proteinsrab GTP-Binding ProteinsVesicle-Associated Membrane Protein 2EndocytosisMembrane ProteinsTetanus ToxinAcrosome ReactionAdrenal MedullaChromaffin GranulesTransport VesiclesIslets of LangerhansSpider VenomsBotulinum ToxinsN-Ethylmaleimide-Sensitive ProteinsQc-SNARE ProteinsQb-SNARE ProteinsCalcium-Binding ProteinsCalcium SignalingSynaptotagmin IIProtein TransportKineticsSignal TransductionPresynaptic TerminalsParameciumMolecular Sequence DataCatecholaminesNeurotransmitter AgentsGTP-Binding ProteinsQuaternary Ammonium CompoundsCytoplasmic VesiclesIonophoresMicroscopy, FluorescenceGoldfishAmino Acid SequenceCattleProtein BindingCell Membrane PermeabilityVesicle-Associated Membrane Protein 3Cell LineInsulinGuanosine 5'-O-(3-Thiotriphosphate)Patch-Clamp TechniquesCarrier ProteinsModels, BiologicalSoluble N-Ethylmaleimide-Sensitive Factor Attachment ProteinsRecombinant Fusion ProteinsMast CellsMicroscopy, ConfocalChromaffin SystemStreptolysinsMice, Inbred C57BLProtein Structure, TertiaryMembrane GlycoproteinsGreen Fluorescent Proteinsral GTP-Binding ProteinsLysosomesActinsMice, KnockoutCalcium ChannelsEgtazic AcidAdenosine TriphosphateOvumMembrane PotentialsMicroscopy, ElectronCalcimycinSpermatozoaFluorescent DyesMutationTime FactorsProtein Kinase CNeuronsParamecium tetraureliaCytotoxicity, ImmunologicInsulin-Secreting CellsCell Degranulation