• Vitro
  • A Magnetic Switch for the Control of Cell Death Signaling in in vitro and in vivo Systems" Nature Materials 2012, 11, 1038. (wikipedia.org)
  • Human breast carcinoma cells infused with metal nanoparticles in vitro have been shown to have an increase in morbidity with exposure to near infrared (NIR). (wikipedia.org)
  • In vitro, photothermal therapy was used in oral epithelial cell lines, (HSC 313 and HOC 3 Clone 8) and one benign epithelial cell line (HaCaT). (wikipedia.org)
  • embryonic
  • Discuss stem cells, adult and embryonic, and their therapeutic potential for MS here. (thisisms.com)
  • It is amazing to see how the Catholic Church and George Bush can hold us all in thrall regarding human embryonic stem cell research. (lifeethics.org)
  • In other words, we can regress human skin cells to an embryonic state by introducing retroviruses including c-Myc (cancer cells) to do so. (lifeethics.org)
  • Here's an idea: instead of trying to create human embryonic stem cells from someone's nose or foreskin, let us do the research on embryos as nature intended. (lifeethics.org)
  • Embryonic stem cells have always had all the problems that Terry mentions - including the retrovirus manipulation in many cases, look up "first transplantable lung cells" from the Houston, Texas Stem cell researchers here and here - in addition to the ethical problem of requiring the destruction of human embryos and the necessity to consider buying or bartering for oocytes. (lifeethics.org)
  • Embryonic stem cells have the same concerns about the ability to reliably direct the cells toward the desired cell line, about the lack of regulation inherent in the primitive cells in culture, and ensuring that a more primitive cell - a future tumor - was not transplanted with the derived, less plastic cells. (lifeethics.org)
  • In the meantime, Wilmut has announced that the science is driving him to abandon embryonic research and cloning (especially using animal oocytes and human nuclear DNA to form a cimera), Yamanaka and Thomson are getting ready to patent and sell their cell lines for drug research and basic science, as well as anticipating future transplants. (lifeethics.org)
  • Lack of ODC causes cell apoptosis in embryonic mice, induced by DNA damage. (wikipedia.org)
  • biotin
  • Holocarboxylase synthetase deficiency is an inherited metabolic disorder in which the body is unable to use the vitamin biotin effectively. (wikipedia.org)
  • Mutations in the HLCS gene reduce the activity of holocarboxylase synthetase, preventing cells from using biotin effectively and disrupting many cellular functions. (wikipedia.org)
  • Biotin is an important component of enzymes involved in metabolizing fats and carbohydrates, influencing cell growth, and affecting amino acids involved in protein synthesis. (wikipedia.org)
  • Biotin is often recommended as a dietary supplement for strengthening hair and nails, though scientific data supporting this outcome are weak. (wikipedia.org)
  • Nevertheless, biotin is found in many cosmetics and health products for the hair and skin. (wikipedia.org)
  • receptor
  • In the inner ear, mechano-electrical transduction by sensory hair cells is usually accepted as the dominant source of two-tone interferences, for the sigmoidal relation between hair-bundle deflections and transduction currents provides a saturating nonlinearity that distorts receptor potentials ( 4 , 5 ). (pnas.org)
  • This displacement of the hair bundles generates a receptor potential in the hair cells. (wikipedia.org)
  • The activated STATs dissociate from the receptor and form dimers before translocating to the cell nucleus, where they regulate transcription of selected genes. (wikipedia.org)
  • El-Sayed et al found that the malignant cells that had undergone incubation in AuNPs conjugated with anti-epithelial growth factor receptor (EGFR) required half the energy to destroy a cell than a benign cell. (wikipedia.org)
  • brainstem
  • When a tadpole initiates a voluntary movement, e.g., begins to swim by moving its tail from side to side, nerve cells in the spinal cord send copies of the motor commands to so-called efferent neurons in the brainstem that project to the hair cells in the inner ear. (eurekalert.org)
  • Hence the whole adaptation process is controlled by neurons in the spinal cord, which transmit signals to the VO via nerve cells located in the brainstem just before the muscles carry out the next locomotory behavior. (eurekalert.org)
  • The direct impact of input from the spinal cord on the sensitivity of sensory nerve cells in the balance organ demonstrates the importance of interactions between sensory and motor systems, and it underlines the significance of the interplay between different components of the central nervous system - in this case, the spinal cord and the brainstem. (eurekalert.org)
  • Spiral ganglion neurons (SGNs) are postsynaptic to hair cells and project to the brainstem. (jneurosci.org)
  • tumor
  • The only problem with this is that it also creates tertomas which are nasty little creatures - effectively a germ cell tumor which may contain hair, teeth, bones, eyeballs, torsos and hands. (lifeethics.org)
  • Gap junction genes are involved in communication between carcinogenic cells and tight junction genes act as tumor suppressors. (wikipedia.org)
  • A tumor consists of a multitude of cell types, and thus targeting a single type of cell is ineffective and potentially dangerous. (wikipedia.org)
  • auditory
  • Then, the inner hair cells translate the vibrations into electrical nerve impulses and send them to the auditory nerve , which connects the inner ear to the brain. (kidshealth.org)
  • When both stimulus frequencies enter the bandwidth of the hair-bundle amplifier, two-tone interferences display level functions that are characteristic both of human psychoacoustics and of in vivo mechanical measurements in auditory organs. (pnas.org)
  • tissue
  • Hirsch et al observed that extreme heating in tumours would cause irreversible tissue damage including coagulation, cell shrinkage and loss of nuclear straining. (wikipedia.org)
  • Besides normal cultivation, D. thapsi has been propagated using explant culture, a technique employed for the isolation of cells from piece(s) of tissue for harvesting. (wikipedia.org)
  • bundles
  • Here we show that active oscillatory movements of single hair-cell bundles elicit two-tone suppression and distortions that are shaped by nonlinear amplification of periodic stimuli near the characteristic frequency of spontaneous oscillations. (pnas.org)
  • skin
  • Murad Clarifying Skin Cleanser, cleanses with salicylic acid to prevent build-up of skin cells and anti-bacterial ingredients to prevent break-outs. (joybeauty.com)
  • Intense pulsed light (IPL) is a technology used by cosmetic and medical practitioners to perform various skin treatments for aesthetic and therapeutic purposes, including hair removal, photorejuvenation (e.g. the treatment of skin pigmentation, sun damage, and thread veins) as well as to alleviate dermatologic diseases such as acne. (wikipedia.org)
  • This light travels through the skin until it strikes the hair shafts or the bulb (root). (wikipedia.org)
  • Certain skin conditions, health irregularities, and medications can impact whether it is safe for a person to receive a light based hair removal treatment. (wikipedia.org)
  • According to Remington, manufacturer of an IPL device, all IPL and laser devices should only be used on light to medium skin tones, and work best on darker hair. (wikipedia.org)
  • It is important to note that these studies utilized a variety of IPL devices on various skin areas, and used patients with varying hair and skin types. (wikipedia.org)
  • The glands deposit sebum on the hairs, and bring it to the skin surface along the hair shaft. (wikipedia.org)
  • Sebum waterproofs and lubricates the skin and hair of mammals. (wikipedia.org)
  • In colder conditions, the nature of sebum becomes more lipid and in coating the hair and skin, rain is effectively repelled. (wikipedia.org)
  • Affected infants often have immunodeficiency diseases, difficulty feeding, breathing problems, a skin rash, hair loss (alopecia), and a lack of energy (lethargy). (wikipedia.org)
  • Exfoliation involves the removal of the oldest dead skin cells on the skin's outermost surface. (wikipedia.org)
  • It is done more frequently than waxing (once a week rather than once a month) since it only destroys hair partially below the skin, rather than destroying the entire root as with waxing. (wikipedia.org)
  • After applying the lather with a brush, the use of a double-edged safety razor or straight razor removes dead skin simply by the fact that the aforementioned razors are dragged much closer across the skin and remove dead skin more effectively than the cartridge or electric razor. (wikipedia.org)
  • The procedure is done by an aesthetician who will gently glide a scalpel across the skin removing the outermost layer of skin cells and hair from the face. (wikipedia.org)
  • Subclinical deficiency can cause mild symptoms, such as hair thinning or skin rash typically on the face. (wikipedia.org)
  • In 2014 researchers discovered that oral JAK inhibitors, when administered orally could restore hair growth in some subjects and that applied to the skin, effectively promoted hair growth. (wikipedia.org)
  • cellular
  • A host of naturally-derived anti-pollutants and antioxidants (Ao 3 , Po 3 and Dx 2 ) seek to neutralise free radical damage and protect against environmental aggressors, effectively reinforcing cellular integrity against oxidative stress to prevent cell deterioration, plus Ec 3 activates cell energy to promote a visibly brighter tone. (hqhair.com)
  • Especially, he employed "Magnetic NanoSwitch" to selectively regulate cellular fate inducing programmed cell death (i.e., apoptosis) and cell growth. (wikipedia.org)
  • Regeneration
  • The SGs are thought to facilitate the coordinated breakdown of the inner root sheath (IRS) during the hair cycle, and thus may be critical for follicular regeneration (Stenn, 2001). (pubmedcentralcanada.ca)
  • growth
  • It is worth noting that the Food and Drugs Administration (FDA) have singled out Minoxidil for its ability to stimulate the process of hair growth. (webnewswire.com)
  • IPL can permanently reduce hair growth, most effectively in darker, coarser hair. (wikipedia.org)
  • It is caused by uncontrolled cell growth, and affects a wide range of cell types and organs in the body. (wikipedia.org)
  • It is also used in the biosynthesis of coenzyme A, which plays a role in a wide range of enzymatic reactions and thus in cell growth. (wikipedia.org)
  • Therefore, ornithine decarboxylase is an essential enzyme for cell growth, producing the polyamines necessary to stabilize newly synthesized DNA. (wikipedia.org)
  • Inactivation of ODC by difluoromethylornithine (eflornithine) is used to treat cancer and facial hair growth in postmenopausal females. (wikipedia.org)
  • Effect of calcium, manganese and lithium on growth and cardenolide content in cell suspension cultures of Digitalis thapsi L". Plant Cell Reports. (wikipedia.org)
  • shaft
  • As the light is absorbed, the bulb and most of the hair shaft are heated, destroying the hair-producing papilla. (wikipedia.org)
  • Victims
  • Tomie is inevitably killed time and again, only to regenerate and spread her curse to other victims, making her effectively immortal. (wikipedia.org)
  • researchers
  • Using tadpoles as an experimental model system, the researchers investigated how the hair cells manage to sense both low- and high-amplitude movements and produce the signals that control the appropriate compensatory response. (eurekalert.org)
  • accelerations
  • One consequence of the similar effects exerted on otolithic hair cells by certain head tilts and linear accelerations is that otolith afferents cannot convey information that distinguishes between these two types of stimuli. (wikipedia.org)
  • sensitivity
  • Sensitivity peaks in the middle of the band and falls off to either side in a lopsided cone shape overlapping the bands of other nearby hair cells. (evolver.fm)
  • There is an upper (and lower) audible frequency limit, past which the sensitivity of the last hair cells drops to zero, and hearing ends. (evolver.fm)
  • Their findings reveal that cells in the spinal cord which generate the rhythmic patterns of neural and muscle activity required for locomotion also adaptively alter the sensitivity of the hair cells in the VO, enabling them to respond appropriately to the broad range of incoming signal amplitudes. (eurekalert.org)
  • The effect of this signal is to reduce the sensitivity of the hair cells," says Chagnaud. (eurekalert.org)
  • structures
  • The resulting light has a spectral range that targets specific structures and chromophores (e.g. melanin in hair, or oxyhemoglobin in blood vessels) that are heated to destruction and reabsorbed by the body. (wikipedia.org)
  • The hair cells are deflected by structures called otoconia. (wikipedia.org)
  • A hair follicle with associated structures. (wikipedia.org)
  • treatments
  • For IPL treatments, an average of 8-10 treatments are required to remove most visible hair. (wikipedia.org)
  • Although IPL treatments will permanently reduce the total number of body hairs, they will not result in a permanent removal of all hair. (wikipedia.org)
  • tissues
  • You might be able to do something similar to how we are currently doing gene therapy where you work on isolated cells or do very specific injections into tissues where it is possible (eyes). (fark.com)
  • body
  • Feedback posted on different forums also indicates that Provillus works by inducing natural changes in the body thereby bypassing some underlying causes of hair loss. (webnewswire.com)
  • work
  • As opposed to multipotent - the fact that his cells did not make teratomas was one criticism of Atala's amniotic stem cell work. (lifeethics.org)
  • Our work distinguishes the frequency-dependent nonlinearity that emerges from the active process that drives the hair bundle into spontaneous oscillations from the passive nonlinear compliance associated with the direct gating of transduction channels by mechanical force. (pnas.org)
  • Convection involves a larger bulk flow of gas driven by buoyancy and temperature differences, and it does not work well in small cells where there is little density difference to drive it. (wikipedia.org)
  • possess
  • The LMU group now intends to study whether all the hair cells in the inner ear also respond to efferent information emanating from the spinal cord or whether the VO possess subpopulations of hair cells that are specialized for reception of impulses that signal either fast or slow movements. (eurekalert.org)
  • process
  • One huge advantage that the new process offers that has never been achieved before, is the ability to make patient specific cells for everyone, not just the elite few who can afford to buy the oocytes. (lifeethics.org)
  • The mechanical coupling of the otoconia to the hair cell sensory sterocilia at the surface of the vestibular sensory epithelium is mediated by two of the extracellular matrix, each on with a specific role in the mechanical transduction process. (wikipedia.org)
  • Sebum is produced in a holocrine process, in which cells within the sebaceous gland rupture and disintegrate as they release the sebum and the cell remnants are secreted together with the sebum. (wikipedia.org)
  • Waxing is a mechanical process that is performed with the intention of plucking the hair, which also functions as a mechanical exfoliant. (wikipedia.org)
  • To effectively target the malignant cells, the AuNPs were conjugated by polyethylene glycol, a process known as PEGylation. (wikipedia.org)
  • fluid
  • The hair cells, which detect the resulting changes in fluid flow in the semicircular canals in the inner ear, enable us to keep our balance without any conscious effort. (eurekalert.org)
  • survival
  • The inner hair cell (IHC) to SGN synapse is susceptible to glutamate excitotoxicity and to acoustic trauma, with potentially adverse consequences to long-term SGN survival. (jneurosci.org)
  • mechanical
  • Because gating of transduction channels is directly coupled to tip-link tension, the hair-cell bundle also acts as a nonlinear spring ( 6 ) that produces mechanical distortions of sound-evoked vibrations ( 7 ). (pnas.org)
  • Found
  • Protein is found in literally every single one of the 30 trillion cells that your effectively when you perform a regular fitness program that includes muscle building workouts. (blogigo.de)
  • Hair count reduction was found to be ~60% (12 weeks), 75% (1 year), 60% (2 year). (wikipedia.org)
  • Exposure
  • The cells are destroyed by exposure to light, rupturing membranes causing the release of digestive enzymes. (wikipedia.org)
  • They determined that the NIR wavelengths were converted into heat on the picosecond timescale, allowing for short exposure of CW to minimize possible exposure to healthy cells. (wikipedia.org)
  • loss
  • Provillus is a hair regrowth formula that is often recommended to individuals suffering from different types of hair loss. (webnewswire.com)
  • Although sixty days is thought to be the average duration one needs to wait, some customers have to wait a little longer than that due to differences in the extent of hair loss, genetics among other deep lying issues. (webnewswire.com)
  • production
  • Production of eumelanin gives hair a black or brown color, while pheomelanin gives hair a red color. (wikipedia.org)
  • This is the first step and the rate-limiting step in humans for the production of polyamines, compounds required for cell division. (wikipedia.org)
  • function
  • These fluids have a unique ionic composition suited to their function in regulating the electrochemical potential of hair cells, which are as we will later see the transducers of the vestibular system. (wikibooks.org)
  • humans
  • The tadpole's balance organs operate on the same principle as the bilateral VOs in humans, and the nerve circuits responsible for communication between the hair cells and the motor neurons in the spinal cord are organized in essentially identical ways. (eurekalert.org)
  • rapidly
  • Binding between monomers is relatively weak, and ODC interconverts rapidly between monomeric and dimeric forms in the cell. (wikipedia.org)