Edema pulmonary veno occlusive disease. Medical search. Frequent questions

TITUSVILLE, N.J. - October 14, 2021 - The Janssen Pharmaceutical Companies of Johnson & Johnson announced today 11* abstracts highlighting data from its pulmonary hypertension (PH) portfolio will be presented at CHEST 2021, the annual meeting of the American College of Chest Physicians, held virtually October 17-20. (jnj.com)
Data presentations from eight abstracts will provide additional evidence supporting the role of objective multiparameter risk assessment approaches in helping to optimize treatment and care for pulmonary arterial hypertension (PAH), as well as the impact of earlier and comprehensive therapy with UPTRAVI ® (selexipag) and OPSUMIT ® (macitentan). (jnj.com)
Our collection of data at CHEST 2021 represents the largest single-congress body of PAH scientific data by Janssen in recent history and underscores our efforts to facilitate earlier, accurate diagnosis and support timely introduction of appropriate PAH therapies," said Sean Studer**, M.D., Vice President, Medical Affairs, Janssen U.S., Pulmonary Hypertension. (jnj.com)
OPSUMIT® is an endothelin receptor antagonist (ERA) indicated for the treatment of pulmonary arterial hypertension (PAH, WHO Group I) to delay disease progression. (globalrph.com)
Increased pressure in these vessels is known as pulmonary arterial hypertension . (medlineplus.gov)
Many cases are likely misdiagnosed as idiopathic pulmonary arterial hypertension , which is increased blood pressure in the pulmonary arteries without a known cause. (medlineplus.gov)
Research suggests that 5 to 25 percent of people diagnosed with idiopathic pulmonary arterial hypertension have PVOD. (medlineplus.gov)
Bosentan, sold under the brand name Tracleer and Safebo among others, is a dual endothelin receptor antagonist medication used in the treatment of pulmonary artery hypertension (PAH). (wikipedia.org)
Bosentan is used to treat people with moderate pulmonary arterial hypertension and to reduce the number of digital ulcers - open wounds on especially on fingertips and less commonly the knuckles - in people with systemic scleroderma. (wikipedia.org)
the exposure to bosentan after intervenous and oral administration is about 2-fold greater in adult patients with pulmonary arterial hypertension than in healthy adult subjects. (wikipedia.org)
It was approved for pulmonary artery hypertension in the US in November 2001, and in the European Union in May 2002. (wikipedia.org)
To measure the prevalence of different types of pulmonary hypertension (PH) and to identify patients with systemic sclerosis (SSc) at highest risk in a multicenter European sample, with a metaanalysis of relevant studies. (jrheum.org)
Precapillary PH was found in 64 patients (5%), of whom 42 had pulmonary arterial hypertension (PAH) and 22 had PH secondary to interstitial lung disease (ILD). (jrheum.org)
Pulmonary hypertension (PH) is a fatal disorder characterized by an increase in pulmonary vascular resistance, which leads to right ventricular failure. (jrheum.org)
The Dana Point classification distinguishes pulmonary arterial hypertension (PAH) from PH secondary to other morbid entities 1 . (jrheum.org)
In a small study of pulmonary hypertension due to left ventricular dysfunction, more patients in the OPSUMIT ® group developed significant fluid retention and had more hospitalizations due to worsening heart failure compared to placebo. (janssencarepath.com)
Pulmonary hypertension, the most severe PC, is associated with uncontrolled disease and use of biologic therapies. (reumatologiaclinica.org)
High disease activity and the use of multiple therapies include disease-modifying anti-rheumatic drugs should be a red flag for clinicians when discounting PC and pulmonary hypertension. (reumatologiaclinica.org)
Pulmonary veno-occlusive disease (PVOD) is one of the less commonly encountered causes of pulmonary hypertension . (medscape.com)
Some reports suggest that PVOD accounts for 5-20% of cases classified as idiopathic pulmonary arterial hypertension (PAH). (medscape.com)
In the past, PVOD has been described by various terms, such as pulmonary venous sclerosis, obstructive disease of the pulmonary veins, or the venous form of primary pulmonary hypertension. (medscape.com)
However, owing to the differences in pathology and response to PAH-specific therapy, it was classified in a unique group 1 in the pulmonary hypertension classification in 2009. (medscape.com)
The plexiform arterial lesions seen in patients with primary pulmonary hypertension, or idiopathic pulmonary arterial hypertension (PAH), are absent, although some arterial medial thickening may occur. (medscape.com)
Some cases of pulmonary hypertension in the setting of mixed connective disease and scleroderma , including the CREST (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) variant, have been known to have a histopathology consistent with that of PVOD. (medscape.com)
Pulmonary hypertension is increased pressure in the pulmonary circulation. (msdmanuals.com)
Severe pulmonary hypertension leads to right ventricular overload and failure. (msdmanuals.com)
Many conditions and drugs cause pulmonary hypertension. (msdmanuals.com)
In the first group (pulmonary arterial hypertension [PAH]), the primary disorder affects the small pulmonary arterioles. (msdmanuals.com)
Sildenafil is a vasoactive agent that is commonly prescribed to treat erectile dysfunction (impotence) in men, and to reduce symptoms in patients with pulmonary arterial hypertension (PAH). (empowerpharmacy.com)
The medication was initially formulated to treat hypertension (a symptom of ischaemic heart disease) and chest pains caused from the inadequacy of the blood circulation to the heart. (empowerpharmacy.com)
Shortly after approval for ED, studies showed sildenafil was effective in treating patients with pulmonary arterial hypertension (PAH). (empowerpharmacy.com)
Although preliminary data from 12 patients with sickle cell anemia showed a decrease in PAH, a larger clinical trial (n = 134) investigating the use of sildenafil for pulmonary hypertension in adults with sickle cell anemia was stopped early due to an increased risk of severe adverse effects, especially sickle cell pain crises, compared to placebo (38% vs. 8%, respectively). (empowerpharmacy.com)
Patients with Pulmonary Hypertension associated with Idiopathic Interstitial Pneumonias (PH-IIP). (adempashcp.com)
For the treatment of pulmonary hypertension to improve exercise ability in persons with WHO Group I pulmonary hypertension. (cialis-canadian-pharma.com)
VELETRI ® is a prostacyclin vasodilator indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) to improve exercise capacity. (janssencarepath.com)
VELETRI ® should be used only by clinicians experienced in the diagnosis and treatment of pulmonary hypertension. (janssencarepath.com)
Because epoprostenol is metabolized rapidly, even brief interruptions in the delivery of VELETRI ® may result in symptoms associated with rebound pulmonary hypertension including dyspnea, dizziness, and asthenia. (janssencarepath.com)
Dosage of VELETRI ® during chronic use should be adjusted at the first sign of recurrence or worsening of symptoms attributable to pulmonary hypertension or the occurrence of adverse events associated with epoprostenol. (janssencarepath.com)
Abrupt withdrawal (including interruptions in drug delivery) or sudden large reductions in dosage of VELETRI ® may result in symptoms associated with rebound pulmonary hypertension, including dyspnea, dizziness, and asthenia. (janssencarepath.com)
Tadalafil tablets are a phosphodiesterase 5 (PDE5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) to improve exercise ability. (nih.gov)
you have pulmonary hypertension associated with idiopathic interstitial pneumonias (PH-IIP). (adempas-us.com)
A Combined Targeted and Whole Exome Sequencing Approach Identified Novel Candidate Genes Involved in Heritable Pulmonary Arterial Hypertension. (nih.gov)
Pulmonary hypertension is high blood pressure in your pulmonary arteries, which carry oxygen-poor blood from your heart to your lungs. (clevelandclinic.org)
Pulmonary hypertension causes your pulmonary arteries to become narrow. (clevelandclinic.org)
What is pulmonary hypertension? (clevelandclinic.org)
Pulmonary hypertension (PH) is a general diagnosis that means you have high blood pressure in your pulmonary arteries . (clevelandclinic.org)
Pulmonary hypertension has many different causes. (clevelandclinic.org)
Pulmonary hypertension is dangerous because it disrupts the flow of blood through your heart and lungs . (clevelandclinic.org)
How does pulmonary hypertension affect my body? (clevelandclinic.org)
Without treatment, pulmonary hypertension can overtax your heart and eventually be fatal. (clevelandclinic.org)
Because pulmonary hypertension can affect your entire body, it's essential that you're diagnosed and treated as early as possible. (clevelandclinic.org)
What are the different types of pulmonary hypertension? (clevelandclinic.org)
The World Health Organization (WHO) divides pulmonary hypertension into five groups based on its cause. (clevelandclinic.org)
Who does pulmonary hypertension affect? (clevelandclinic.org)
Pulmonary hypertension can affect adults at any age. (clevelandclinic.org)
This is called persistent pulmonary hypertension of the newborn (PPHN) . (clevelandclinic.org)
How common is pulmonary hypertension? (clevelandclinic.org)
Some types of PH are rare, such as pulmonary arterial hypertension (PAH) and PH caused by blood clots. (clevelandclinic.org)
However, lung biopsy is hazardous in patients with severe pulmonary hypertension, and there is a need for noninvasive diagnostic tools in this patient population. (nih.gov)
Patients with PVOD may be refractory to pulmonary arterial hypertension (PAH)-specific therapy and may even deteriorate with it. (nih.gov)
High-resolution computed tomography of the chest can suggest PVOD in the setting of pulmonary hypertension when it shows nodular ground-glass opacities, septal lines, lymph node enlargement, and pleural effusion. (nih.gov)
Similarly, occult alveolar hemorrhage found on bronchoalveolar lavage in patients with pulmonary hypertension is associated with PVOD. (nih.gov)
We retrospectively reviewed 48 cases of severe pulmonary hypertension: 24 patients with histologic evidence of PVOD and 24 randomly selected patients with idiopathic, familial, or anorexigen-associated PAH and no evidence of PVOD after meticulous lung pathologic evaluation. (nih.gov)
This medicine also treats pulmonary hypertension, a type of high blood pressure affecting the arteries in the lungs. (discountacnemeds.com)
Pulmonary arterial hypertension: 40 mg once daily. (discountacnemeds.com)
Severe hepatic impairment (Child-Pugh class C) when used for pulmonary arterial hypertension. (discountacnemeds.com)
This drug also treats pulmonary hypertension, a type of high blood pressure that affects the arteries in the lungs. (redlightpharma.com)

Macitentan displays high affinity and sustained occupancy of the ET receptors in human pulmonary arterial smooth muscle cells. (globalrph.com)
Obstructive proliferative vasculopathy of the small and medium-size pulmonary arterial circulation and chronic hypoxemia due to advanced lung disease are major causes of precapillary PH in SSc 7 , 8 . (jrheum.org)
People with peripheral arterial disease are at a risk of heart attack or stroke. (powershow.com)
Medicines like Cilostazol (Pletal), are used to treat symptoms of peripheral arterial disease and to manage health conditions that contribute to the risk of heart attack and stroke. (powershow.com)
Surgery is only carried out in cases of severe peripheral arterial disease (PAD) like disabling intermittent claudication, open sores (ulcers that dont heal), or sore skin, bone and tissue problems (gangrene). (powershow.com)

Pulmonary veno-occlusive disease (PVOD) is characterized by the blockage (occlusion) of the blood vessels that carry oxygen-rich (oxygenated) blood from the lungs to the heart (the pulmonary veins). (medlineplus.gov)
however, it is unknown how absence of this protein's function leads to the pulmonary vessel abnormalities that underlie PVOD. (medlineplus.gov)
Regardless of the mechanism of injury, the end result in pulmonary veno-occlusive disease (PVOD) is constriction and/or occlusion of the pulmonary veins and venules. (medscape.com)
The exact etiology of pulmonary veno-occlusive disease (PVOD) remains largely unknown. (medscape.com)
Pulmonary veno-occlusive disease (PVOD) is defined by specific pathologic changes of the pulmonary veins. (nih.gov)
A definite diagnosis of PVOD thus requires a lung biopsy or pathologic examination of pulmonary explants or postmortem lung samples. (nih.gov)
Among the 16 PVOD patients who received PAH-specific therapy, 7 (43.8%) developed pulmonary edema (mostly with continuous intravenous epoprostenol, but also with oral bosentan and oral calcium channel blockers) at a median of 9 days after treatment initiation. (nih.gov)

Pulmonary Embolism (PE) Pulmonary embolism (PE) is the occlusion of pulmonary arteries by thrombi that originate elsewhere, typically in the large veins of the legs or pelvis. (msdmanuals.com)
these pressures are transmitted to the left atrium, pulmonary veins, and pulmonary capillary bed. (basicmedicalkey.com)

More than 600 drugs are known to cause pulmonary toxicity, and illicit drugs are well-known to result in pulmonary toxicities. (medscape.com)

Janssen will present a post-hoc analysis of GRIPHON (the largest randomized, controlled trial ever conducted in PAH patients) based on the Registry to Evaluate Early and Long-Term PAH Disease Management (REVEAL) Lite 2 risk calculator. (jnj.com)
Pulmonary edema in patients with pulmonary veno-occlusive disease. (globalrph.com)
Consecutive patients with SSc recruited at 11 French and Italian centers underwent detailed evaluations, including Doppler echocardiography, chest computed tomography, pulmonary function tests, and right-heart catheterization (RHC), to detect the presence and causes of PH. (jrheum.org)
RHC identified 17 patients (1%) with postcapillary PH secondary to left-heart disease. (jrheum.org)
The metaanalysis of 3818 patients showed a prevalence of precapillary PH of 9% (95% CI 6%-12%) and identified advanced age, longer disease duration, and limited cutaneous disease subset as risk factors for this condition. (jrheum.org)
Studies establishing effectiveness included predominantly patients with NYHA Functional Class III-IV symptoms and etiologies of idiopathic or heritable PAH or PAH associated with connective tissue diseases. (janssencarepath.com)
VELETRI ® should not be used chronically in patients who during dose initiation develop pulmonary edema, which may be associated with pulmonary veno-occlusive disease. (janssencarepath.com)
Unless contraindicated, administer anticoagulant therapy to patients receiving VELETRI ® to reduce the risk of pulmonary thromboembolism or systemic embolism through a patent foramen ovale. (janssencarepath.com)
Hypotension: Carefully consider whether patients with certain underlying cardiovascular disease, could be adversely affected by vasodilatory effects of tadalafil. (nih.gov)
Not recommended in patients with pulmonary veno-occlusive disease. (nih.gov)
Cyclophosphamide is a antineoplastic , immunosuppressive agent that is FDA approved for the treatment of malignant diseases , minimal change nephrotic syndrome in pediatric patients. (wikidoc.org)
Pulmonary edema can be life-threatening, but effective therapy is available to rescue patients from the deleterious consequences of disturbed lung fluid balance, which usually can be identified and, in many instances, corrected. (thoracickey.com)
Methods IDA in end-stage renal disease patients on HD was observed in 42 (33.6%) of 125 patients. (go.jp)
Seventy-five percent of patients (46/61) were transplanted with active disease. (clustermed.info)
KEYTRUDA was also granted accelerated approval in September 2019, and received full approval in July 2021, in combination with LENVIMA ® (lenvatinib) for the treatment of patients with advanced endometrial carcinoma that is not MSI-H or dMMR, who have disease progression following prior systemic therapy in any setting and are not candidates for curative surgery or radiation. (businesswire.com)
Our research with KEYTRUDA has contributed to recent advances in the treatment of gastric cancer, and we are continuing to advance studies to help more patients with this disease. (merck.com)
While these results are not what we hoped for, we are proud of the foundational role that KEYTRUDA has established in the treatment of certain types of lung cancer, and we are committed to continuing to research how we can further improve responses to our medicines for patients with difficult-to-treat forms of the disease. (streetinsider.com)

Disease progression included: death, initiation of intravenous (IV) or subcutaneous prostanoids, or clinical worsening of PAH (decreased 6-minute walk distance, worsened PAH symptoms and need for additional PAH treatment). (globalrph.com)
The diagnosis of drug-mediated pulmonary toxicity is usually established based on clinical findings. (medscape.com)
The purpose of this study was to evaluate the implications of the 2018 updated guideline for the diagnosis of idiopathic pulmonary fibrosis (IPF) in clinical practice compared to 2011 guideline. (bvsalud.org)
Pulmonary edema-defined as excessive extravascular water in the lungs-is a common and serious clinical problem. (thoracickey.com)
The clinical syndrome is characterized by hemoptysis, falling hematocrit, hypoxemic respiratory failure and diffuse pulmonary infiltrates. (medscape.com)
Pulmonary function tests (PFTs) may show a restrictive lung function defect or a lowtrending diffusing capacity for CO without necessarily the presence of clinical symptoms or definite changes on imaging including HRCT. (pneumotox.com)
We compared clinical and radiologic findings, pulmonary function, and hemodynamics at presentation, as well as outcomes after the initiation of PAH therapy in both groups. (nih.gov)
Acute vasodilator testing with nitric oxide and clinical, functional, or hemodynamic characteristics were not predictive of the subsequent occurrence of pulmonary edema on treatment. (nih.gov)

Because rational and effective therapy depends on understanding basic principles of normal and abnormal liquid, solute, and protein transport in the lungs, this chapter begins with a brief overview of the major factors that govern fluid and protein filtration in healthy lungs before focusing on the pathophysiology of pulmonary edema. (thoracickey.com)

Single Stage Repair of Aortic Coarctation and Coronary Artery Bypass Grafting in a 55-Year- Old-Man Presenting with Pulmonary Edema. (ouhsc.edu)
Diagnosis is made by finding elevated pulmonary artery pressure (estimated by echocardiography and confirmed by right heart catheterization). (msdmanuals.com)
During dose initiation, asymptomatic increases in pulmonary artery pressure coincident with increases in cardiac output occurred rarely. (janssencarepath.com)
What exactly peripheral artery disease is? (powershow.com)
Peripheral artery disease, known as (PAD), is a narrowing of the peripheral arteries of the legs, stomach, arms, and head (common in the arteries of the legs). (powershow.com)
PAD is somewhat similar to coronary artery disease (CAD). (powershow.com)
For more Infomation about peripheral artery disease and treatment. (powershow.com)

Experimental interstitial pulmonary edema. (ouhsc.edu)
Most drug-induced pulmonary toxicities involve the parenchyma, thus, interstitial infiltrates may be demonstrated on radiographs. (medscape.com)
BACKGROUND: Idiopathic Pulmonary Fibrosis (IPF) is one of the most common idiopathic interstitial pneumonia, which can occur all over the world. (bvsalud.org)
Rationale: Usual interstitial pneumonia (UIP) is the defining morphology of idiopathic pulmonary fibrosis (IPF). (bvsalud.org)

In general, the presence of elevated fibrin degradation products, thrombocytopenia, and sometimes opening and severe post-transplant sinusoidal obstruction syndrome formerly termed hepatic veno-occlusive disease after six months, thrombocytosis and more than atypical lymphocytes are not reliable for showing the transmission of cmv. (albionfoundation.org)

In addition, left-heart disease and thromboembolic disease may cause, respectively, postcapillary/venous and precapillary PH 10 , 11 . (jrheum.org)
We present a case of a school-age female with sJIA who died of acute cardiopulmonary instability secondary to pulmonary venous-occlusive disease demonstrated by necropsy. (reumatologiaclinica.org)
With cardiogenic pulmonary edema, fluid accumulation results from elevations in pulmonary venous and capillary hydrostatic pressures. (basicmedicalkey.com)
Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle. (lookformedical.com)

To minimize the potential morbidity and mortality from drug-induced respiratory diseases, healthcare providers should be familiar with the possible adverse effects of the medications they prescribe. (medscape.com)

The safety and effectiveness for the treatment of nephrotic syndrome in adults or other renal disease has not been established. (pillintrip.com)
Pulmonary renal syndromes, connective tissue disorders and drugs make up the majority of the cases of DAH. (medscape.com)

[ 9 ] The alveolar capillaries become dilated and engorged from back-pressure and sometimes causes capillary proliferation, which mimics another similar disease, pulmonary capillary hemangiomatosis. (medscape.com)

Although the term pulmonary veno-occlusive disease was first used in the 1960s, the first case was described by Dr J. Hora in 1934 in a 48-year-old patient who died within one year of diagnosis with symptoms of right-sided heart failure. (medscape.com)
Drug-induced pulmonary toxicity is a diagnosis of exclusion. (medscape.com)
In general, bronchoscopy with transbronchial biopsy is not helpful in establishing the diagnosis of drug-induced pulmonary toxicity. (medscape.com)
Transbronchial biopsy, however, may aid in the diagnosis of pulmonary involvement by other diseases such as sarcoidosis, metastatic cancer, or lymphoma. (medscape.com)

Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. (ouhsc.edu)
Diffuse alveolar hemorrhage (DAH) is a life-threatening disorder characterized clinically by the presence of hemoptysis, falling hematocrit, diffuse pulmonary infiltrates and hypoxemic respiratory failure. (medscape.com)

Pulmonary Fibrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
This graph shows the total number of publications written about "Pulmonary Fibrosis" by people in this website by year, and whether "Pulmonary Fibrosis" was a major or minor topic of these publications. (umassmed.edu)
Below are the most recent publications written about "Pulmonary Fibrosis" by people in Profiles. (umassmed.edu)
Contribution of Fetal, but Not Adult, Pulmonary Mesothelium to Mesenchymal Lineages in Lung Homeostasis and Fibrosis. (umassmed.edu)
Brodeur TY, Robidoux TE, Weinstein JS, Craft J, Swain SL, Marshak-Rothstein A. IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells. (umassmed.edu)
Smoking-associated fibrosis and pulmonary asbestosis. (umassmed.edu)

The interest in PH due to systemic sclerosis (SSc), the connective tissue disease most often associated with PH, has recently increased 2 . (jrheum.org)
Systemic juvenile idiopathic arthritis (sJIA) is a chronic childhood inflammatory disease. (reumatologiaclinica.org)
VELETRI ® is a potent pulmonary and systemic vasodilator. (janssencarepath.com)

Symptoms vary with the stage of pulmonary edema. (basicmedicalkey.com)
Other individuals have a multitude of the most severe symptoms of end-stage liver disease and a limited chance for survival. (medscape.com)
Specific medical therapies may be applied to many liver diseases in an effort to diminish symptoms and to prevent or forestall the development of cirrhosis. (medscape.com)

Because blood flow through the lungs is difficult, pressure rises in the vessels that carry blood that needs to be oxygenated to the lungs from the heart ( the pulmonary arteries ). (medlineplus.gov)
Because of the increased blood pressure in the pulmonary arteries, the heart must work harder than normal to pump blood to the lungs, which can eventually lead to fatal heart failure. (medlineplus.gov)
High blood pressure in your pulmonary arteries causes these arteries to become narrow. (clevelandclinic.org)
Blood clots in your pulmonary arteries. (clevelandclinic.org)
High blood pressure in your pulmonary arteries forces your heart to work harder to send oxygen-poor blood to your lungs. (clevelandclinic.org)
PAH makes your pulmonary arteries become narrow, thick or stiff. (clevelandclinic.org)
Less blood can flow through, which raises the pressure in your pulmonary arteries. (clevelandclinic.org)
Blood backs up in your heart, raising the pressure in your pulmonary arteries. (clevelandclinic.org)
Less blood can flow through your lungs, raising the pressure in your pulmonary arteries. (clevelandclinic.org)

Peripheral edema and fluid retention are known consequences of PAH and ERAs. (janssencarepath.com)

Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening. (ouhsc.edu)
Alterations in pulmonary alveoli after a single injection of monocrotaline. (ouhsc.edu)
A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. (umassmed.edu)
A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. (uchicago.edu)

As the condition worsens, affected individuals can develop a bluish tint to the skin (cyanosis), chest pains, fainting spells, and an accumulation of fluid in the lungs ( pulmonary edema ). (medlineplus.gov)
Pulmonary edema results when fluid is filtered into the lungs faster than it can be removed from them. (thoracickey.com)
Lung structure relevant to the forces governing fluid and protein movement in healthy lungs and lungs with pulmonary edema has been the subject of classic and more recent reviews. (thoracickey.com)

A list of drugs that are reported to cause pulmonary toxicity is available on the continually updated Website PNEUMOTOX online . (medscape.com)

Most children have prevention & treatment of obstructive lung disease, so increased doses ie, more than days may be depressed or overwhelmed. (albionfoundation.org)

Nearly 100% of people with severe mitral valve disease . (clevelandclinic.org)
The Association between Positive Tracheal Aspirate Cultures and Adverse Pulmonary Outcomes in Preterm Infants with Severe Bronchopulmonary Dysplasia. (jefferson.edu)

Update in nonneoplastic lung diseases. (uchicago.edu)

Diffuse alveolar hemorrhage (DAH) is a life-threatening condition which refers to hemorrhage originating in the pulmonary microvasculature, rather than from the bronchial circulation or parenchymal abnormalities. (medscape.com)

In the pulmonary vascular area, it also relaxes the smooth muscle, causing vasodilatation and decreased lung vascular resistance. (discountacnemeds.com)

A common complication of cardiac disorders, pulmonary edema can occur as a chronic condition or develop quickly and rapidly become fatal. (basicmedicalkey.com)
It's usually a complication of heart disease or lung disease. (clevelandclinic.org)
Secondary pulmonary alveolar proteinosis: a confusing and potentially serious complication of hematologic malignancy. (uchicago.edu)

In addition to the risk of causing birth defects and of causing liver damage, bosentan has a high risk of causing edema, pulmonary veno-occlusive disease, decreasing sperm counts, and decreases in hemoglobin and hematocrit. (wikipedia.org)
Pulmonary function testing (PFTs) primarily results in a restrictive lung disease pattern, with decreases in the total lung capacity (TLC). (medscape.com)

Treatment is with pulmonary vasodilators and diuretics. (msdmanuals.com)

Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT ® , some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported. (janssencarepath.com)
With pulmonary edema, fluid accumulates in the extravascular spaces of the lung. (basicmedicalkey.com)

This increased pulmonary capillary hydrostatic force promotes transudation of intravascular fluids into the pulmonary interstitium, decreasing lung compliance and interfering with gas exchange. (basicmedicalkey.com)

Risk factors for pulmonary embolism are. (msdmanuals.com)

Bosentan blocks both ET-A and ET-B receptors, but is thought to exert a greater effect on ET-A receptors, causing a total decrease in pulmonary vascular resistance. (wikipedia.org)

An unusual case of unilateral pulmonary edema with contralateral bronchial obstruction. (ouhsc.edu)
It refers to bleeding that originates in the pulmonary microvasculature instead of the parenchyma or bronchial circulation. (medscape.com)

Pulmonary venoocclusive disease is also a recognized cause of PH, which is thought to be more common in connective tissue diseases 9 . (jrheum.org)

DAH is characterized clinically by hemoptysis, falling hematocrit, hypoxemic respiratory failure and diffuse pulmonary infiltrates. (medscape.com)

Anatomy42

Diseases70

Chemicals and Drugs15

Analytical, Diagnostic and Therapeutic Techniques and Equipment90

Phenomena and Processes16

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture4

Information Science7

Health Care37

Geographicals2

Hypertension67

Arterial5

PVOD7

Veins2

Result in pulmonary1

Patients17

Clinical8

Pathophysiology1

Artery7

Interstitial4

Sinusoidal obstruct1

Venous4

Morbidity and morta1

Renal2

Capillary hemangiomatosis1

Diagnosis4

Disorder2

Fibrosis6

Systemic3

Symptoms3

Arteries9

Peripheral1

Alveoli4

Lungs3

Cause pulmonary1

Obstructive1

Severe2

Lung Diseases1

Alveolar hemorrhage1

Relaxes the smooth1

Complication3

Decreases2

Treatment1

Fluid2

Hydrostatic1

Embolism1

Receptors1

Bronchial2

Connective tissue d1

Infiltrates1