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Echovirus InfectionsEnterovirusEnterovirus InfectionsEchovirus 9Enterovirus B, HumanEchovirus 6, HumanEnterovirus A, HumanMeningitis, AsepticHand, Foot and Mouth DiseaseMeningitis, ViralEnteroviruses, PorcineEnterovirus D, HumanEnterovirus, BovinePoliovirusCoxsackievirus InfectionsAntigens, CD55SewagePicornaviridaeHerpanginaRNA, ViralVirus CultivationCerebrospinal FluidDisease OutbreaksCapsid ProteinsWater MicrobiologyPhylogenyReceptors, VirusSerotypingParalysisMolecular Sequence DataParechovirusEncephalitis, ViralVirusesGenome, ViralCapsidVirologyNeutralization Tests5' Untranslated RegionsSequence Analysis, DNACytopathogenic Effect, ViralRhinovirusFecesHaplorhiniPicornaviridae InfectionsOrphanagesReverse Transcriptase Polymerase Chain ReactionHemagglutination, ViralAntibodies, ViralSkin ManifestationsGlutaralMolecular EpidemiologyViral Structural ProteinsRhabdomyosarcomaViral Plaque AssayAdsorptionViral ProteinsReoviridaePolymerase Chain ReactionVirus ReplicationInfant, NewbornIntegrin alpha2beta1SeasonsWater PollutionBase SequencePoliomyelitisCercopithecus aethiopsCell LineConjunctivitis, Acute Hemorrhagic
CoxsackievirusesGenusInfectionsPoliovirusesEncephalitisAseptic meningitisSerotypeViral meningitisAdenovirusRisk of contractiSerotypes of enterovirusCoxsackievirus A16EV71Neonatal enteroviral sepsisEntericInfectEnteroviralPicornavirus familySevereReceptorEpidemiologyOutbreakPrimersHumansDetectionsHuman orphanDetection2021Meningitis100,000NewbornsRespiratoryClinicalTypeAcute infectionTransmissionOutbreaksSpecimensAntiviralSurveillancePolioGroup
Coxsackieviruses7
  • Other viruses, including Coxsackieviruses and echoviruses, were added to the genus based on their physical and chemical properties. (virology.ws)
  • Herpangina is another clinical syndrome that has been associated with the echoviruses (although is more commonly caused by coxsackieviruses). (logicalimages.com)
  • The most dominant epitope was highly conserved among enterovirus species, including HFMD-related coxsackieviruses, HFMD-unrelated echoviruses and polioviruses. (epivax.com)
  • The most common causes of viral meningitis is a group of viruses known as enteroviruses, which includes coxsackieviruses and echoviruses. (mn.us)
  • Enteroviruses are divided into 5 subgenera: polioviruses, group A coxsackieviruses, group B coxsackieviruses, echoviruses, and the newer enteroviruses. (medscape.com)
  • Human coxsackieviruses belong to the family Picornaviridae and genus Enterovirus . (blogspot.com)
  • We reviewed the antiviral activity and molecular mechanism of flavonoids against coxsackieviruses, rhinoviruses, and enterovirus-A71 that contribute to severe neurological and cardiomyopathy, colds, and asthma among viruses in Enterovirus. (apub.kr)
Genus9
Infections9
  • CI = 0--0.4) than infections with other enteroviruses. (cdc.gov)
  • NESS data allowed identification and description of a core group of consistently circulating enteroviruses that probably determine the disease burden associated with enterovirus infections. (cdc.gov)
  • Echovirus 11 infections of newborns with mortality during the 1979 enterovirus season in Milwaukee, Wis. (cdc.gov)
  • noun Any of various enteroviruses of the gastrointestinal tract associated with certain diseases, such as viral meningitis, mild respiratory infections, and severe diarrhea in newborns. (wordnik.com)
  • Infectious disease experts in the U.S. report a slight rise in enterovirus infections among newborns. (nbcnews.com)
  • Frequency, viral loads, and serotype identification of enterovirus infections in Scottish blood donors. (ox.ac.uk)
  • Although the infrastructure established for PCR-based screening for HCV RNA would allow parallel screening for enteroviruses, any decision concerning donor testing would require further information on the outcome of transfusion-acquired enterovirus infections. (ox.ac.uk)
  • Suspected enterovirus or parechovirus infections. (canada.ca)
  • Human infections with enteroviruses such as coxsackievirus A (CVA) are generally mild, but severe complications were more often reported for infections caused by enterovirus 71 (EV71) ( 1 , 2 ). (blogspot.com)
Polioviruses2
  • A committee sponsored by the National Foundation for Infantile Paralysis categorized EVs and other enteroviruses (ie, coxsackievirus group A and group B, polioviruses) together in 1957. (medscape.com)
  • Echoviruses were first isolated from the feces of asymptomatic children in the context of epidemiological studies of polioviruses. (medscape.com)
Encephalitis2
  • Enteroviruses are associated with diverse clinical syndromes ranging from minor febrile illness to severe, potentially fatal conditions (e.g., aseptic meningitis, encephalitis, paralysis, myocarditis, and neonatal enteroviral sepsis) and could be linked with the development of some chronic diseases (e.g., type 1 diabetes and dilated cardiomyopathy) ( 1,2 ). (cdc.gov)
  • Encephalitis due to echoviruses has also been reported. (logicalimages.com)
Aseptic meningitis3
  • Enteroviruses are common human viruses associated with various clinical syndromes, from minor febrile illness to severe, potentially fatal conditions (e.g., aseptic meningitis, paralysis, myocarditis, and neonatal enteroviral sepsis). (cdc.gov)
  • Enteroviruses (EVs) are the most common agents of aseptic meningitis. (muni.cz)
  • Enteroviruses play the most important role in the differential diagnosis of aseptic meningitis. (muni.cz)
Serotype4
  • Echovirus 9 (also known as E-9, E.C.H.O. 9, and formerly Coxsackie A23 or A23 virus) is a serotype of echovirus. (wikipedia.org)
  • Enterovirus detections by serotype with specimen type, collection date, and demographic information are reported monthly by participating laboratories to CDC, which summarizes the data and disseminates the results. (cdc.gov)
  • Enteroviruses infect millions of people worldwide each year, and the infection can result in a wide variety of symptoms depending on the serotype of the enterovirus. (norgenbiotek.com)
  • Laboratory surveillance for NPEVs and HPeV is based on published protocols that take advantage of the correlation between the partial VP1 sequence and the enterovirus (EV) serotype and parechovirus genotype. (canada.ca)
Viral meningitis3
  • We hypothesize that the cluster of viral meningitis cases and the EFVS were different manifestations of the same infection, caused by a strain of echovirus type 4 (E4) virus. (cdc.gov)
  • Echoviruses can result in a variety of neurological manifestations, including acute viral meningitis . (logicalimages.com)
  • Viral meningitis is typically caused by enteroviruses, such as the coxsackievirus and echovirus. (faithway.info)
Adenovirus1
Risk of contracti1
Serotypes of enterovirus3
Coxsackievirus A161
  • Coxsackievirus A16, echoviruses 11 and 30, and enterovirus 71 were most often identified. (ox.ac.uk)
EV713
  • We were recently contacted by researchers at the Pasteur Institute of Beijing (Ruichen Wei, Qiben Leng) who were grappling with an out break of Hand-Foot-Mouth Disease, a serious infection caused by enterovirus 71 (EV71) among other viruses. (epivax.com)
  • Our findings seem to suggest that CD4+ T cell responses to poliovirus following vaccination , or to other enteroviruses to which individuals may be exposed in early childhood, may have a modulating effect on subsequent CD4+ T cell response to EV71 infection . (epivax.com)
  • Enterovirus 71 (EV71), a pathogen that causes not only HFMD but also neurological complications and even death, has caused many HFMD outbreaks in China. (biomedcentral.com)
Neonatal enteroviral sepsis1
  • Though enteroviruses are common, cases of neonatal enteroviral sepsis have historically been rare. (nbcnews.com)
Enteric4
  • These orphan viruses were initially termed ECHO, an acronym for enteric cytopathic human orphan virus, which was later simplified to echovirus. (medscape.com)
  • The term enterovirus reflects enteric transmission of the virus via person-to-person spread. (medscape.com)
  • Completed Enteroviruses and Enteric viruses requisition form. (canada.ca)
  • The ECHO virus (echovirus) is the abbreviation for Enteric Cytopathic Human Orphan (ECHO). (recipeguide.info)
Infect3
  • Enteroviruses can infect all tissues of the human body. (medscape.com)
  • Most enteroviruses cause a very mild disease in the children that they infect," Dr. Mike Ryan, the executive director of the World Health Organization's health emergencies program, said in a briefing Wednesday. (nbcnews.com)
  • More than 100 types of enteroviruses can infect people, according to the CDC. (nbcnews.com)
Enteroviral2
  • The Centers for Disease Control and Prevention doesn't have an active reporting system for neonatal enteroviral disease or enteroviruses in general. (nbcnews.com)
  • CONCLUSIONS: The detection of enterovirus-positive blood units indicates the potential for enteroviral transmission by blood components. (ox.ac.uk)
Picornavirus family1
  • On the basis of its physical, chemical, and biological properties, the virus was classified as an enterovirus in the picornavirus family. (virology.ws)
Severe3
Receptor2
  • The neonatal Fc receptor (FcRn) has been recognized as a pan-echovirus receptor expressed on intestinal enterocytes (primary site of infection) and liver hepatocytes and microvascular endothelial cells lining the blood-brain barrier (secondary sites of infection). (medscape.com)
  • Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage. (expasy.org)
Epidemiology3
  • We describe the epidemiology of 95 laboratory-confirmed meningitis cases and conclude that the epidemic fever and vomiting syndrome was caused by the same enterovirus. (cdc.gov)
  • Molecular epidemiology and evolutionary trajectory of emerging echovirus 30, Europe. (szu.cz)
  • The epidemiology of non-polio enteroviruses: recent advances and outstanding questions. (apub.kr)
Outbreak1
  • Viral protein 1 nucleotide sequencing demonstrated 96% homology with an echovirus 4 strain responsible for a large outbreak of meningitis in the Yanbian Prefecture of China in 1996. (cdc.gov)
Primers4
  • Correct, the current test uses PCR with pan-enterovirus primers, followed by sequencing to determine the genotype. (virology.ws)
  • Partial EV and HPeV VP1 sequences are amplified from clinical isolates or direct specimens by RT- semi nested PCRs (RT-snPCR) using generic primers that target all human enterovirus serotypes and parechovirus genotypes to date. (canada.ca)
  • These samples were also positive by reverse transcription PCR (RT-PCR) with pan-enterovirus primers (5′-CAAGCACTTCTGTBWCCCCGG-3′ and 5′-GAAACACGGACACCCAAAGTAGT-3′) specific for the 5′ untranslated region (5′-UTR) as described ( 3 - 5 ). (blogspot.com)
  • Because sequence analysis of the 5′-UTR amplicon showed that this enterovirus strain was closely related to other human enterovirus A strains, another set of consensus primers (5′-TGCCCACAYCARTGGATHAA-3′ and 5′-CCTGACCACTGNGTRTARTA-3′) specific for the viral protein 2-viral protein 3 region of human enterovirus A was used for typing. (blogspot.com)
Humans2
  • It is a common cause of illness in humans, although unlike many enteroviruses, it rarely infects infants. (wikipedia.org)
  • BACKGROUND: Enteroviruses are non-enveloped, frequently pathogenic RNA viruses infecting humans. (ox.ac.uk)
Detections3
  • During 1970--2005, a total of 52,812 enterovirus detections were reported to NESS (29,772 of them during 1983--2005). (cdc.gov)
  • Enterovirus detections had prominent summer-fall seasonality, with June--October accounting for 77.9% of reports with known month of specimen collection. (cdc.gov)
  • Upsurge in echovirus 30 detections in five EU/EEA countries, April to September, 2018. (eurosurveillance.org)
Human orphan1
Detection2
20211
  • Re-emergence of enterovirus D68 in Europe after easing the COVID-19 lockdown, September 2021. (szu.cz)
Meningitis1
  • In July 2007, a cluster of meningitis cases caused by an echovirus 4 strain was detected in 1 indigenous community in the Top End of the Northern Territory of Australia. (cdc.gov)
100,0001
  • Viral loads ranged from 500 (the lower cutoff of the assay) to greater than 100,000 amplifiable enterovirus template copies per mL. (ox.ac.uk)
Newborns3
  • Enteroviruses can severely affect newborns, whose immune systems aren't mature enough to fight off infection. (nbcnews.com)
  • The cases in Europe, however, have prompted Creech and his colleagues to make sure pediatricians and families with newborns are aware of the potential for enteroviruses. (nbcnews.com)
  • Creech's team is already treating more newborns hospitalized with enteroviruses than usual. (nbcnews.com)
Respiratory4
  • Within her first hours, she developed respiratory distress and was transferred to Children's Hospital, where physicians identified liver failure caused by echovirus . (wordnik.com)
  • Readers might wonder why a virus that causes respiratory illness is called an enterovirus. (virology.ws)
  • Echoviruses can cause an upper respiratory infection. (logicalimages.com)
  • Echoviruses can be spread by fecal matter or by breathing in respiratory droplets, and they usually live in the digestive system. (nbcnews.com)
Clinical2
  • If possible include clinical and travel history and any enterovirus or parechovirus lab test results completed at local or provincial laboratories. (canada.ca)
  • Sensitive, Semi-nested PCR Amplification of VP1 Sequences for Direct Identification of All Enterovirus Serotypes from Original Clinical Specimens. (canada.ca)
Type5
  • Echovirus 9 is the most common enterovirus type. (wikipedia.org)
  • Nucleotide sequencing of the whole genome verified this enterovirus (AUS250G) as a strain of echovirus type 4. (cdc.gov)
  • Enterovirus infection has also been associated with the onset of type I diabetes mellitus. (loinc.org)
  • On Friday, the WHO confirmed that at least 26 infants in Croatia, France, Italy, Spain, Sweden and the United Kingdom had been infected with a rare type of enterovirus, called echovirus-11. (nbcnews.com)
  • Hober D, Sauter P. Pathogenesis of type 1 diabetes mellitus: interplay between enterovirus and host. (apub.kr)
Acute infection2
Transmission2
  • Given that viral circulation has been disrupted by the COVID-19 pandemic, we remain vigilant to any changes in enterovirus transmission. (nbcnews.com)
  • Vigilant monitoring of this emerging recombinant enterovirus is needed to prevent its transmission to other regions. (blogspot.com)
Outbreaks1
  • Although we do not have routine surveillance of enteroviruses, CDC does have other surveillance systems that we use to monitor and quickly assess signals for outbreaks and increases in specific types of enteroviruses," Dr. Janell Routh, the head of the CDC's division of viral diseases, said in a statement. (nbcnews.com)
Specimens1
Antiviral1
Surveillance4
  • The National Enterovirus Surveillance System (NESS) is a voluntary, passive surveillance system that has monitored trends in circulating enteroviruses since 1961. (cdc.gov)
  • Efforts to increase laboratory participation in NESS should continue to allow for more complete and accurate surveillance for enteroviruses. (cdc.gov)
  • Labs that perform their own enterovirus and/or parechovirus PCR testing should submit positive samples for genotyping surveillance. (canada.ca)
  • Prospective enterovirus D68 (EV-D68) surveillance from September 2015 to November 2018 indicates a current wave of activity in Wales. (eurosurveillance.org)
Polio3
  • These include the polio virus, coxsackie A and B, and echovirus. (seleneriverpress.com)
  • The life cycle of non-polio enteroviruses and how to target it. (apub.kr)
  • Enterovirus D68 - The New Polio? (apub.kr)
Group2
  • While it was decided to keep the name 'enterovirus' for this group of viruses, it is certainly confusing and I would argue that it should be replaced by a more descriptive name. (virology.ws)
  • Many of the viruses in the enterovirus group love to show themselves during the summer months. (seleneriverpress.com)