EndotrachealInstillationTracheal intubationMechanical ventilationAirwayLaryngealTranslaryngealInhalationTracheostomyNasalMiceFacilitateTopical applicationPercutaneousPatientsClinicalOralCasesDaysStudyControlStudiesOrotrachealCardiac arrestIntensive care2021MortalityEmergentOccurComplicationsVentilatoryLaryngoscopeEfficacyIncidenceDoseClinicalDistressAdministrationDetectCommonlyTranslationObjectiveLungDetermineEmergencyInjuryTrialAvoidRemainsLateWeeks
Endotracheal15
- Laryngotracheal injury secondary to endotracheal intubation results from ischemic necrosis, which develops within hours of intubation, with injury severity increasing with duration of intubation. (elsevierpure.com)
- Continuous endotracheal intubation ranged from several hours to 33 days. (elsevierpure.com)
- Although endotracheal intubation is required for airway maintenance in many patients with respiratory dysfunction, the procedure carries risks. (elsevierpure.com)
- We add para-arytenoid pseudodiverticulum formation to the list of possible complications of endotracheal intubation. (elsevierpure.com)
- Gwin, C & Robinson, MJ 2007, ' Para-arytenoid cartilage pseudodiverticulum formation as a sequela of endotracheal intubation ', Archives of Pathology and Laboratory Medicine , vol. 131, no. 9, pp. 1378-1381. (elsevierpure.com)
- Robinson, Morton J. / Para-arytenoid cartilage pseudodiverticulum formation as a sequela of endotracheal intubation . (elsevierpure.com)
- 5 , 6 Tracheal stenosis is a known risk of long-term intubation, however, and has also been associated with tracheostomy Tracheal stenosis resulting from endotracheal intubation versus tracheostomy does appear to differ in mechanism, morphology, and location. (rcjournal.com)
- 7 Tracheal stenosis from prolonged endotracheal intubation can occur anywhere from the ETT tip to the glottic/subglottic area, but the most common site is where the cuff has been in contact with the mucosa (one third of cases). (rcjournal.com)
- TOPICAL APPLICATION: For laryngoscopy, bronchoscopy and endotracheal intubation, the pharynx may be sprayed with 1−5 mL (40−200 mg of lidocaine HCl), i.e., 0.6−3 mg/kg or 0.3−1.5 mg/lb body weight. (pfizermedicalinformation.com)
- Therefore, the aim of this study was to evaluate the potential consequences of the endotracheal CP assessment maneuver on CP levels and ETV in the early postoperative of coronary artery bypass grafting (CABG). (biomedcentral.com)
- Inclusion criteria were age 18 years or older, oral endotracheal intubation, and conventional mechanical ventilation (MV). Patients with obesity, chronic respiratory disease, laryngeal disease or anomaly, and difficult intubation (two or more trials), were excluded from the study. (biomedcentral.com)
- Prolonged translaryngeal endotracheal intubation increases the risk of ventilator-associated pneumonia (VAP) by bypassing and disabling the laryngeal mechanisms, promoting oropharyngeal contamination of the bronchial tree and lung. (rcjournal.com)
- 1 In addition, prolonged translaryngeal endotracheal intubation is associated with the development of sinusitis 2 and may cause severe laryngeal and tracheal damage. (rcjournal.com)
- Placement of a tracheostomy has become a viable alternative to prolonged endotracheal intubation, with the benefits of improving patient comfort, reducing need for sedation, lowering airway resistance, and allowing for easier airway care. (rcjournal.com)
- Endotracheal intubation is an intricate process critical to maintaining airways during advanced neonatal resuscitation and administering surfactant to treat respiratory distress syndrome in premature infants. (actascientific.com)
Instillation5
- Intratracheal instillation is the introduction of a substance directly into the trachea. (wikipedia.org)
- Intratracheal instillation was reported as early as 1923 in studies of the carcinogenicity of coal tar. (wikipedia.org)
- As compared to inhalation, intratracheal instillation allows greater control over the dose and location of the substance, is cheaper and less technically demanding, allows lower amounts of scarce or expensive substances to be used, allows substances to be tested that can be inhaled by humans but not small mammals, and minimizes exposure to laboratory workers and to the skin of laboratory animals. (wikipedia.org)
- Intratracheal instillation is often performed with mice, rats, or hamsters, with hamsters often preferred because their mouth can be opened widely to aid viewing the procedure, and because they are more resistant to lung diseases than rats. (wikipedia.org)
- The CG100 product candidate is a recombinant human CC10 protein, a secretory protein that is believed to play an important protective role in the lung via maintenance of airway epithelia, delivered by intratracheal instillation in intubated neonates. (grahamsfoundation.org)
Tracheal intubation3
- Tracheal intubation Driscoll, Kevin E. (wikipedia.org)
- Neonatal outcomes after failed tracheal intubation during obstetric general anaesthesia for caesarean section: Secondary analysis of a UKOSS case-control study. (ox.ac.uk)
- Similarly, World War II physician-anesthetists showed they could provide complex anesthesia care, such as pentothal administration, regional anesthesia, and tracheal intubation, with aplomb and gained the support of surgical colleagues who facilitated their growth within a medical profession. (silverchair.com)
Mechanical ventilation5
- The effects of early percutaneous dilational tracheotomy compared with delayed tracheotomy in critically ill medical patients needing prolonged mechanical ventilation were assessed. (nih.gov)
- The early tracheotomy group spent less time in the intensive care unit (4.8 +/- 1.4 vs. 16.2 +/- 3.8 days) and on mechanical ventilation (7.6 +/- 2.0 vs. 17.4 +/- 5.3 days). (nih.gov)
- BACKGROUND: Interventions that lead to earlier liberation from mechanical ventilation can improve patient outcomes. (bvsalud.org)
- Tracheostomy prevents laryngeal or upper airway damage from prolonged translaryngeal intubation, allows easy/frequent access to the lower airway for suctioning, and provides a stable airway in a patient who requires prolonged mechanical ventilation. (rcjournal.com)
- Additionally, any need for secondary intubation/mechanical ventilation (MV) and occurrence of complications were determined. (bmj.com)
Airway1
- RATIONALE: Controversies and practice variations exist related to the pharmacologic and nonpharmacologic management of the airway during rapid sequence intubation (RSI). (sccm.org)
Laryngeal3
- To demonstrate laryngeal injury, specifically pseudodiverticulum formation, as a result of intubation. (elsevierpure.com)
- The earliest manifestations of laryngeal injury occurred within hours and included hyperemia, edema, and ovoid mucosal lesions over the arytenoid and inner posterolateral cricoid cartilages. (elsevierpure.com)
- Laryngeal injury from intubation is very common, and the severity of injury is directly related to the duration of intubation. (elsevierpure.com)
Translaryngeal3
- Early group showed significantly less mortality (31.7% vs. 61.7%), pneumonia (5% vs. 25%), and accidental extubations compared with the prolonged translaryngeal group (0 vs. 6). (nih.gov)
- There was also significantly more damage to mouth and larynx in the prolonged translaryngeal intubation group. (nih.gov)
- This study demonstrates that the benefits of early tracheotomy outweigh the risks of prolonged translaryngeal intubation. (nih.gov)
Inhalation1
- Wistar Kyoto (WKY) rats at various times over 6 months after administration of a single 60- to 100-min intratracheal inhalation of iridium-192 (192Ir)-radiolabeled NPs. (cdc.gov)
Tracheostomy2
- Although there was initial enthusiasm in support of early tracheostomy to improve patient outcomes, repeated studies have been unable to produce robust benefits. (rcjournal.com)
- The ideal timing (early vs late) and techniques (percutaneous dilatational, other new percutaneous techniques, open surgical) for tracheostomy have been topics of considerable debate. (rcjournal.com)
Nasal1
- Only kidney and nasal epithelium show specific tissue affinities at these early time intervals. (europa.eu)
Mice2
- The distribution of 14C-test substance was studied in female and 14.5-day-pregnant mice by whole-body autoradiography after administrating 6.5-6.7 mg test substance/kg bw (11-14 uCi/mouse) by oral intubation. (europa.eu)
- On day 14.5 of gestation five mice, weighing 36-45 g, were administered the 14C-test substance (6.5-6.7 mg test substance/kg bw, 11-14 µCi/mouse) by oral intubation. (europa.eu)
Facilitate1
- This new piece of equipment will greatly facilitate the process of complex intratracheal intubation for our physicians in the emergency room and will facilitate the work of the anesthesiologist in the surgery room. (ndh.on.ca)
Topical application1
- In general, the rate of absorption of local anesthetic agents following topical application occurs most rapidly after intratracheal administration. (nih.gov)
Percutaneous2
- Patients were prospectively randomized to either early percutaneous tracheotomy within 48 hrs or delayed tracheotomy at days 14-16. (nih.gov)
- Large observational studies used to compare groups (eg, early vs late tracheotomy, percutaneous vs open procedure, and ICU vs floor decannulation) can be conducted with little cost, yet require sophisticated statistical techniques to control for confounding factors, indication bias, and survivor bias. (rcjournal.com)
Patients5
- It gives credence to the practice of subjecting this group of critically ill medical patients to early tracheotomy rather than delayed tracheotomy. (nih.gov)
- BUS-PTNB offers a encouraging, sensible and also doable method in acquiring muscle example regarding severely sick patients beneath intratracheal intubation. (trpv-antagonist.com)
- Primary outcome was in-hospital mortality up to 28 days after intubation of COVID-19 patients. (bvsalud.org)
- Results: Among 1,966 mechanically ventilated patients with COVID-19, 1,198 (61%) died within 28 days after intubation, 46 (2%) were transferred to other hospitals outside of the Northwell Health system, 722 (37%) survived in the hospital until 28 days or were discharged after recovery. (bvsalud.org)
- It presents with non-specific symptoms depending on the level of the obstruction, which means that its diagnosis is not usually early, with repercussions on the clinical deterioration of the patient, being serious especially in elderly patients and with comorbidities. (bvsalud.org)
Clinical3
- It may well aid the particular pathological medical diagnosis or any other tissue-based exams for intubated individuals and enhance clinical results.BUS-PTNB supplies a offering, useful as well as feasible strategy in getting cells example for severely not well individuals below intratracheal intubation. (trpv-antagonist.com)
- Society of Critical Care Medicine clinical practice guidelines for rapid sequence intubation in the critically ill adult patient. (sccm.org)
- In order to improve the early diagnosis, prevention and treatment of SD in clinical practice, the book also provides extensive data on its pathophysiological mechanism, epidemiology and etiology, together with detailed analyses. (nshealth.ca)
Oral1
- One female mouse, weighing 33.5 g was also administered 6.6 mg 14C-test substance/kg (10.3 µCi) by oral intubation and sacrificed 3 hr later. (europa.eu)
Cases1
- This new piece of equipment will be used in complex cases of intratracheal intubation and will allow doctors to easily visualize on a monitor, the trachea and the vocal cords in order to insert a tube. (ndh.on.ca)
Days1
- Pseudodiverticulum formation occurred as early as 8 days of continuous intubation. (elsevierpure.com)
Study1
- Early VTE prophylaxis in severe traumatic brain injury: A propensity score weighted EAST multicenter study. (ucsf.edu)
Control1
- Consequently, pelvic injury symbolizes an important problem to properly and also early understand, control, and also treat. (trpv-antagonist.com)
Studies1
- Er zijn meerdere studies verricht naar het effect van antibiotische profylaxe bij dreigende vroeggeboorte, met en zonder prematuur gebroken vliezen, op uitstel van de vroeggeboorte en mortaliteit, en morbiditeit bij de pasgeborene. (richtlijnendatabase.nl)
Orotracheal2
- Several cases are presented which reveal the clinical value of dental damages that occur during orotracheal intubation, oral endoscopy or seismotherapy. (nih.gov)
- Airway: Perform emergent orotracheal intubation in patients displaying signs of acute or impending respiratory distress. (medscape.com)
Cardiac arrest1
- UNRECOGNIZED esophageal intubation can lead to progressive hypoxia, cardiac arrest, neurologic injury, and death. (asahq.org)
Intensive care2
- To compare the short-term morbidity of early-term vs term neonates in a county-based birth cohort using the primary objective of admission to a neonatal intensive care unit (NICU) or neonatology service. (nih.gov)
- [3-6] In the emergency setting involving out-of-hospital, emergency department, and intensive care unit intubations, however, where esophageal intubation is perhaps more likely to occur, [7] capnometry is not always available. (asahq.org)
20211
- Airway anticipates early data in Q4 2021. (cliniexpert.com)
Mortality1
- Mortality was higher in the "late group" than in the "early group" (37 vs. 32%, p (bvsalud.org)
Emergent2
- Unplanned extubation (UE) is an important quality metric in the neonatal ICU that is associated with hypoxia, bradycardia, and risk for airway trauma with emergent re-intubation. (rcjournal.com)
- UEs are associated with significant risk for adverse events, including hypoxia, hypercarbia, bradycardia and code events, increased risk of intracranial hemorrhage, and trauma to the larynx, pharynx, and trachea with emergent re-intubation. (rcjournal.com)
Occur1
- However, if an airway is to be placed, it is unknown whether this should occur early or late in the sequence of resuscitation events. (nih.gov)
Complications1
- A high index of suspicion is required for early detection of complications, most commonly diverticular abscess and colovesical fistula. (omeka.net)
Ventilatory1
- Breathing: Ventilatory distress that persists beyond competent intubation indicates a possible tension pneumothorax, which requires needle decompression and chest tube placement. (medscape.com)
Laryngoscope1
- Polhemus, Colchester, VT) was used to assess the amount of angular and linear translation in 3 planes during intubation trials with each of 4 devices (Airtraq laryngoscope, lighted stylet, intubating LMA, and Macintosh laryngoscope). (londonspine.com)
Efficacy2
- median Acute Physiology and Chronic Health Evaluation [APACHE] II score, 26) were included in the analysis after the trial was stopped early based on predefined criteria for efficacy. (nih.gov)
- We studied the SIB during emergency intubations to test its efficacy outside of the operating room. (asahq.org)
Incidence1
- There were 19 esophageal intubations (6% incidence). (asahq.org)
Dose1
- A small dose serves to blunt the hemodynamic responses of tachycardia or hypertension associated with larynogoscopy and intubation. (theanesthesiaconsultant.com)
Clinical2
- The clinical trial will confirm the feasibility of intratracheal administrations of AT-100 and its safety and tolerability. (cliniexpert.com)
- It may well aid the particular pathological medical diagnosis or any other tissue-based exams for intubated individuals and enhance clinical results.BUS-PTNB supplies a offering, useful as well as feasible strategy in getting cells example for severely not well individuals below intratracheal intubation. (trpv-antagonist.com)
Distress1
- Their absence, impaction and/or delayed eruption create significant distress often leading to early presentation to the dental office. (bvsalud.org)
Administration2
- Most intubations were performed using direct laryngoscopy after administration of a hypnotic agent and a muscle relaxant, with cricoid pressure applied until correct placement of the ETT was verified. (asahq.org)
- In general, the rate of absorption of local anesthetic agents following topical application occurs most rapidly after intratracheal administration. (nih.gov)
Detect1
- A 2200 K. pneumoniae mutant library previously obtained by signature-tagged mutagenesis was screened in static and dynamic culture models to detect clones impaired at early and/or mature stages of biofilm formation. (academicconcepts.net)
Commonly1
- CONCLUSION: In a cadaver model of C5-C6 instability, the greatest amount of motion was caused by the most commonly used intubation device, the Macintosh blade. (londonspine.com)
Translation1
- Intubation with the Lightwand resulted in significantly less motion in all tested parameters (other than ML translation) as compared with the Macintosh blade. (londonspine.com)
Objective1
- OBJECTIVE: We sought to evaluate various intubation techniques and determine which device results in the least cervical motion in the setting of a global ligamentous instability model. (londonspine.com)
Lung1
- Active Surveillance of Engineered Stone Workers Facilitates Early Identification of Silicosis: A Discussion of Surveillance of Occupational Lung Diseases. (ucla.edu)
Determine1
- The negative-pressure test using a self-inflating bulb (SIB) during emergency intubation was studied to determine its reliability and predictive value in this setting. (asahq.org)
Emergency3
- The SIB proved to be a sensitive and specific test for esophageal intubation in the emergency setting when used according to the protocol described, and it is complementary to carbon dioxide detection. (asahq.org)
- All intubations were performed in the intensive care units (56%), the emergency trauma center (35%), or elsewhere (9%) by an anesthesiology attending physician or a resident. (asahq.org)
- Intubation was performed by either an emergency medical technician or by a board-certified attending anesthesiologist. (londonspine.com)
Injury1
- Consequently, pelvic injury symbolizes an important problem to properly and also early understand, control, and also treat. (trpv-antagonist.com)
Trial1
- In a randomised controlled trial, Sprague-Dawley rats (n = 61) were allocated to three ventilation groups after intratracheal LPS ( Salmonella enteritidis ) instillations. (ersjournals.com)
Avoid1
- There is need for more enlightenment with regards to early presentation for dental problems to avoid expensive and time-consuming treatments. (bvsalud.org)
Remains1
- Early surgical drainage remains the main method of treating deep neck abscesses. (academicconcepts.net)
Late1
- A total of 28 mutants were affected during late phases of biofilm formation, whereas 16 mutants displayed early adhesion defect. (academicconcepts.net)
Weeks1
- Gestational age of early term (37(0/7)-38(6/7) weeks) vs term (39(0/7)-41(0/7) weeks). (nih.gov)