• Parkinson-plus syndromes (PPS) are a group of neurodegenerative diseases featuring the classical features of Parkinson's disease (tremor, rigidity, akinesia/bradykinesia, and postural instability) with additional features that distinguish them from simple idiopathic Parkinson's disease (PD). (wikipedia.org)
  • Many people who have heard of Parkinson' disease associate this condition with the physical symptoms of tremor or rigidity. (whathealth.com)
  • These serum and cerebrospinal fluid (CSF) autoimmune stiff-person disorders panels can be used for the evaluation of patients with stiffness, spasms, hyperekplexia, limb rigidity, myoclonus, or limb dystonia in the presence or absence of encephalopathy. (arupconsult.com)
  • The usual signs of meningitis are fever, neck pain and rigidity, and painful muscle spasms. (merckvetmanual.com)
  • Caffeine withdrawal symptoms often lead to shaking or trembling muscle activity that's often mistaken for hypothermia. (asapland.com)
  • Formerly called Shy-Drager syndrome, the condition shares many Parkinson's disease-like symptoms, such as slowness of movement, muscle rigidity and poor balance. (weheal.org)
  • The motor symptoms of Parkinson's are based around involuntary movements or rigidity (in which muscles of the body 'freeze up' and do not work). (whathealth.com)
  • Dehydration is associated with shivering as it causes muscles to feel stiff and achy which leads to increased involuntary movements. (asapland.com)
  • Additional features include bradykinesia, early-onset postural instability, increased rigidity in axial muscles, dysautonomia, alien limb syndrome, supranuclear gaze palsy, apraxia, involvement of the cerebellum including the pyramidal cells, and in some instances significant cognitive impairment. (wikipedia.org)
  • Stiff-person spectrum disorders encompass classical stiff-person syndrome, partial/focal stiff-person forms such as stiff-limb and stiff-trunk, pure cerebellar ataxia, and a severe encephalomyelitic form referred to as progressive encephalomyelitis with rigidity and myoclonus (PERM). (arupconsult.com)
  • In the lower limb, the muscle power was zero with absent tendon reflexes in the lower limb and impaired abdominal reflex below T10 level. (bvsalud.org)
  • Patients with PERM exhibit a more severe form that also includes dysautonomia, encephalopathy (often with seizures), and myoclonus (muscle jerking). (arupconsult.com)
  • Classic PKAN is characterized by early-childhood onset of progressive dystonia, dysarthria, rigidity, and choreoathetosis. (beds.ac.uk)
  • Some primary muscle disorders may be characterised by muscle hypertrophy rather than atrophy. (vin.com)
  • Severe hypoglycemia or low blood sugar that results in lethargy or loss of consciousness is often associated with shaking movements that occur out of stress causing the muscles to tighten up which leads to involuntary tremors. (asapland.com)
  • Physical injury to the brain can also result in involuntary muscle movements that are uncontrolled and sudden. (asapland.com)
  • It distributes to both the brain (where it causes sedation) and also the spinal cord (where it causes muscle relaxation). (emcrit.org)
  • Intrathecal baclofen administration allows for greater concentrations in the spinal cord (achieving greater muscle relaxation) without higher levels in the brain (which would cause sedation). (emcrit.org)
  • He had multiple spontaneous fasciculations in both the thighs and right deltoid and these later involved the intercostal muscles, neck and face muscles. (bvsalud.org)
  • Deficiency of vitamin B 6 or riboflavin is known to cause muscle weakness, fatigue, irritability along with shivering. (asapland.com)
  • Provides references to other listings for evaluating visual or mental impairments caused by multiple sclerosis and provides criteria for evaluating the impairment of individuals who do not have muscle weakness or other significant disorganization of motor function at rest, but who do develop muscle weakness on activity as a result of fatigue. (nickortizlaw.com)
  • This usually results in permanent muscle weakness, paralysis, vision loss, and respiratory failure to which the patient ultimately succumbs to. (epainassist.com)
  • Kuntz inches out of bed, muscles stiff and tendons tight, and swallows the first of four-to-five daily rounds of medication. (uky.edu)
  • Feline neuromuscular diseases may be classified according to their location as those involving peripheral nerves and/or nerve roots, those involving the neuromuscular junction, and those that involve muscle (1). (vin.com)
  • Peripheral nerve and muscle diseases result in varying degrees of paresis, muscle atrophy, hyporeflexia, and hypotonia. (vin.com)
  • Sometimes called Lou Gehrig's disease, ALS is a progressive, invariably fatal neurological disease that attacks the nerve cells (motor neurons) responsible for controlling voluntary muscles. (nickortizlaw.com)
  • BACKGROUND: Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare neurological condition with paraneoplastic etiology in about 20% of cases, usually presenting before or shortly after the oncological diagnosis is established. (bvsalud.org)
  • Experts have correlated dysautonomia and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) as conditions that could help determine treatment strategies. (aarc.org)
  • Dysautonomia is a significant non-motor feature as well as a neuropsychiatric symptom. (bmj.com)
  • Even more striking was that over 75% of people surveyed did not know that rigidity, in which a person is unable to move their body (or certain body parts) is a key motor symptom of this disease. (whathealth.com)
  • Two muscles control the tension between the hammer and tympanic membrane, as well as between the oval window and stirrup, namely the stapedius and tensor tympani muscles. (mskneurology.no)
  • Additional features include bradykinesia, early-onset postural instability, increased rigidity in axial muscles, dysautonomia, alien limb syndrome, supranuclear gaze palsy, apraxia, involvement of the cerebellum including the pyramidal cells, and in some instances significant cognitive impairment. (wikipedia.org)
  • or in adulthood as parkinsonism (shuffling gait, rigidity, bradykinesia, hypomimia, and monotone speech) unresponsive to L-dopa treatment. (nih.gov)
  • Symptoms include dystonia (a movement disorder resulting in muscular spasms, twisting and repetitive movements) spasticity, parkinsonism (slurred or slow speech, stiffness of the muscles, slow movement, and visible tremors), and cognitive decline. (nih.gov)
  • About 60% of people living with Parkinson's disease experience pain due to stiffness and muscle rigidity (numbness). (blocks.care)
  • The pain associated with Parkinson's disease affects the muscles or joints in the absence of visible injury. (blocks.care)
  • The dystrophinopathies cover a spectrum of X-linked muscle disease ranging from mild to severe that includes Duchenne muscular dystrophy, Becker muscular dystrophy, and DMD-associated dilated cardiomyopathy (DCM). (beds.ac.uk)
  • The severe end of the spectrum includes progressive muscle diseases that are classified as Duchenne/Becker muscular dystrophy when skeletal muscle is primarily affected and as DMD-associated DCM when the heart is primarily affected. (beds.ac.uk)
  • Becker muscular dystrophy (BMD) is characterized by later-onset skeletal muscle weakness. (beds.ac.uk)
  • Spinal muscular atrophy (SMA) is characterized by muscle weakness and atrophy resulting from progressive degeneration and irreversible loss of the anterior horn cells in the spinal cord (i.e., lower motor neurons) and the brain stem nuclei. (beds.ac.uk)
  • Clonus is a reflex response that includes involuntary and rhythmic muscle contractions. (nih.gov)
  • Abrupt discontinuation of intrathecal baclofen, regardless of the cause, has resulted in sequelae that include high fever, altered mental status, exaggerated rebound spasticity, and muscle rigidity, that in rare cases has advanced to rhabdomyolysis, multiple organ-system failure and death. (nih.gov)
  • Titrate baclofen injection to maintain some degree of muscle tone and allow occasional spasms. (nih.gov)
  • Intrathecal baclofen administration allows for greater concentrations in the spinal cord (achieving greater muscle relaxation) without higher levels in the brain (which would cause sedation). (emcrit.org)
  • Dysautonomia after traumatic brain injury: a forgotten syndrome? (medscape.com)
  • There was muscle rigidity, frequent facial grimacing, rhythmic abdominal contractions, kicking motions of the legs, and intermittent dystonic postures of the right arm. (medscape.com)
  • Despite the milder skeletal muscle involvement, heart failure from DCM is a common cause of morbidity and the most common cause of death in BMD. (beds.ac.uk)
  • The nonprogressive myopathy predominantly affects the proximal muscles, and results in early motor delays. (nih.gov)
  • Chorea is a movement disorder that causes sudden, unintended, and uncontrollable jerky movements of the muscles in the face, arms, or legs. (nih.gov)
  • Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by loss of muscle atonia and abnormal dream-enactment behaviors during REM sleep [ 1 ]. (e-jsm.org)
  • It distributes to both the brain (where it causes sedation) and also the spinal cord (where it causes muscle relaxation). (emcrit.org)
  • The mild end of the spectrum includes the phenotypes of asymptomatic increase in serum concentration of creatine phosphokinase (CK) and muscle cramps with myoglobinuria. (beds.ac.uk)