- The semicircular canals enclose the slender semicircular ducts. (medscape.com)
- During mouse embryonic development, a subpopulation of neural crest cell-derived melanocytes migrates and incorporates into a subregion of the cochlear epithelium, forming the intermediate cell layer of the stria vascularis. (jneurosci.org)
- In characterizing the molecular differentiation of developing peripheral auditory structures, we discovered that hepatocyte growth factor ( Hgf ) is expressed in the future stria vascularis of the cochlear epithelium. (jneurosci.org)
- Its receptor tyrosine kinase, c-Met , is expressed in the cochlear epithelium and melanocyte-derived intermediate cells in the stria vascularis. (jneurosci.org)
- Genetic dissection of HGF signaling via c-MET reveals that the incorporation of the melanocytes into the future stria vascularis of the cochlear duct requires c-MET signaling. (jneurosci.org)
- The cochlea is a bony, spiral-shaped chamber that contains the cochlear duct of the membranous labyrinth. (medscape.com)
- The sense of hearing is provided by receptors within the cochlear duct. (medscape.com)
- Beginning in the fifth week of development, the auditory vesicle also gives rise to the cochlear duct, which contains the spiral organ of Corti and the endolymph that accumulates in the membranous labyrinth. (medscape.com)
- The vestibular wall separates the cochlear duct from the perilymphatic scala vestibuli, a cavity inside the cochlea. (medscape.com)
- The basilar membrane separates the cochlear duct from the scala tympani, a cavity within the cochlear labyrinth. (medscape.com)
- The lateral wall of the cochlear duct is formed by the spiral ligament and the stria vascularis, which produces the endolymph. (medscape.com)
- The hair cells develop from the lateral and medial ridges of the cochlear duct, which together with the tectorial membrane make up the spiral organ of Corti. (medscape.com)
- Paint-filled membranous labyrinths of Otx1 −/ − mutants showed an absence of the lateral semicircular canal, lateral ampulla, utriculosaccular duct and cochleosaccular duct, and a poorly defined hook (the proximal part) of the cochlea. (biologists.com)
- The stria vascularis is a nonsensory structure that is essential for auditory hair cell function by maintaining potassium concentration of the scala media. (jneurosci.org)
- The utricular division of the auditory vesicle also responds to angular acceleration, as well as the endolymphatic sac and duct that connect the saccule and utricle. (medscape.com)
- It is secreted by the secretory cells of the stria vascularis of the cochlea and by the dark cells (present in the utricle and near the ampullated ends of semicircular ducts). (medicoapps.org)
- High in K + and low in Na + , it is generated and maintained largely by marginal cells of the stria vascularis in the cochlea and dark cells of the vestibular system in the mammalian ear. (biologists.com)
- The utricular division of the auditory vesicle also responds to angular acceleration, as well as the endolymphatic sac and duct that connect the saccule and utricle. (medscape.com)
- Endolymphatic duct and sac. (medicoapps.org)
- Three transmission lines along three ducts (scala vestibule, media and tympani). (rochester.edu)