AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and Processes
AtropineMuscarinic AntagonistsParasympatholyticsAtropine DerivativesReceptors, MuscarinicHexamethonium CompoundsAcetylcholinePralidoxime CompoundsPhysostigmineParasympathomimeticsParasympathetic Nervous SystemVagus NerveCarbacholMydriaticsMuscle, SmoothPirenzepineNeostigmineAutonomic AgentsElectric StimulationOrganophosphate PoisoningMethacholine CompoundsGuinea PigsMuscle ContractionPropranololGuanethidineGlycopyrrolateVagotomyMuscarinic AgonistsPhentolamineHeart RateCholinesterase ReactivatorsCholinesterase InhibitorsBethanecholAntidotesTetrodotoxinIleumGastrointestinal MotilityCholinergic FibersAutonomic Nervous SystemBethanechol CompoundsBradycardiaOxotremorineDogsSalivationReceptors, CholinergicPreanesthetic MedicationQuinuclidinyl BenzilateCholinergic AgonistsScopolamine HydrobromideCholinergic AgentsDose-Response Relationship, DrugCholinergic AntagonistsGanglionic BlockersMuscarineDichlorvosTropanesSympatholyticsHistamineStomachCatsPentolinium TartrateMuscle RelaxationSomanBretylium CompoundsMecamylamineDepression, ChemicalUrinary BladderTracheaReceptor, Muscarinic M3NorepinephrineVasoactive Intestinal PeptideMethysergideGastric JuiceSecretory RateMetiamideDimethylphenylpiperazinium IodideOphthalmic SolutionsSubstance PReflexPhenoxybenzamineReceptor, Muscarinic M2SympathomimeticsBlood PressurePilocarpineGastric FundusN-MethylscopolamineTachykininsMetipranololAdjuvants, AnesthesiaReceptor, Muscarinic M1Sympathetic Nervous SystemSplanchnic NervesSolanaceous AlkaloidsBenzilatesParotid GlandDicyclomine
SulfateOphthalmicContain atropineIsopto AtropineMuscarinicPediatricLomotilSubtherapeutic0.01OverdoseAlcoholAntidiarrheal drugsDoseVagalAutoinjectorDosesAcetylcholineParenteralActive ingredientOINTMENTCholinesteraseAdenosineSubstancesOpioidDropsDiseasesMedicationsEphedrineIngredientsGenericSymptomaticDosageCocaineEffectsBreast milkReceptorAdverseCardiacAllergicMedicinesSymptomsTreatmentReceptorsHeart rateGenericsBrand
Sulfate13
  • Atropine sulfate eye drops is used to dilate the pupil before eye exams. (drugs.com)
  • Use of atropine sulfate eye drops in children younger than 3 months old is not recommended. (drugs.com)
  • Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of atropine sulfate eye drops in the elderly. (drugs.com)
  • A subtherapeutic amount of atropine sulfate is present to discourage deliberate overdosage. (nih.gov)
  • Diphenoxylate hydrochloride and atropine sulfate is effective as adjunctive therapy in the management of diarrhea. (nih.gov)
  • When you take the drug as a tablet of codeine sulfate, it can help prevent diarrhea. (healthline.com)
  • Atropine Sulfate dilates your pet's pupils prior to eye examinations. (vetdepot.com)
  • Atropine Sulfate is an anti-muscarinic and works by blocking receptors in the eye muscles that are involved in controlling the shape of the lens and the size of the pupils. (vetdepot.com)
  • Atropine Sulfate 15 mg, Sodium Chloride 9 mg, Benzyl Alcohol (preservative) 1%, Water for Injection q.s. (vetdepot.com)
  • Atropine Sulfate is intended for use on animals only. (vetdepot.com)
  • Atropine sulfate blocks the muscarinic effects of acetylcholine that cause bronchorrhoea, hypersalivation, bronchoconstriction and bradycardia, thereby reducing these effects. (who.int)
  • A subtherapeutic dose of anticholinergic atropine sulfate is added to discourage overdosage, in which case diphenoxylate may clinically mimic the effects of codeine. (medscape.com)
  • Each tab of Lomotil (or 5 cc of elixir) contains 2.5 mg diphenoxylate hydrochloride and 0.025 mg atropine sulfate. (medscape.com)
Ophthalmic1
Contain atropine2
  • Other medicines may also contain atropine and diphenoxylate. (medlineplus.gov)
  • Medicines with these names contain atropine and diphenoxylate: Lofene Logen Lomanate Lomotil Lonox Other medicines may also contain atropine and diphenoxylate. (nih.gov)
Isopto Atropine15
Muscarinic3
Pediatric1
  • Vyluma announces FDA acceptance of New Drug Application for NVK002, its novel investigational treatment for pediatric myopia. (empr.com)
Lomotil1
  • Lomotil contains two drugs that can be harmful in large amounts. (medlineplus.gov)
Subtherapeutic1
  • A test to determine the blood level of the antiarrhythmic reveal the drug was present in a slightly subtherapeutic level. (pharmacology2000.com)
0.011
  • The Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) for NVK002 (low dose atropine 0.01%) for the treatment of children with myopia. (empr.com)
Overdose2
  • A case of Lazarus phenomenon associated with a drug overdose seen in the emergency department is presented. (bmj.com)
  • We have been unable to find any reports in the literature of this phenomenon related to drug overdose. (bmj.com)
Alcohol2
  • One author suggest avoiding large doses of pre-mixed atropine containing alcohol preservatives in children out of concern that alcohol toxicity could complicate the situation. (cdc.gov)
  • Tell your doctor if you have glaucoma, you recently had stomach or urinary tract surgery, or you have been addicted to alcohol or drugs. (stlukes-stl.com)
Antidiarrheal drugs1
  • If a patient fails to respond to simple antidiarrheal drugs, anti-inflammatory or immunosuppressive medications may be required. (medscape.com)
Dose3
  • After a 5 mg oral dose of carbon-14 labeled diphenoxylate hydrochloride in ethanolic solution was given to three healthy volunteers, an average of 14% of the drug plus its metabolites was excreted in the urine and 49% in the feces over a four-day period. (nih.gov)
  • Urinary excretion of the unmetabolized drug constituted less than 1% of the dose, and diphenoxylic acid plus its glucuronide conjugate constituted about 6% of the dose. (nih.gov)
  • It has been suggested that when these physiological changes do not occur with this dose (sometimes referred to as an atropine challenge ), this is indicative of cholinesterase inhibitor toxicity. (cdc.gov)
Vagal2
  • The goal of atropine administration is to improve conduction through the AVN by reducing vagal tone via atropine-induced receptor blockade. (medscape.com)
  • Bezold and Bloebaum showed that atropine blocked the effects of vagal stimulation on the heart in 1867. (wikipedia.org)
Autoinjector1
  • These atropine autoinjectors are packaged with a 2-PAM autoinjector, called Mark I kits. (cdc.gov)
Doses5
  • Type of cholinesterase inhibitor toxicity that may require extremely high doses of atropine. (cdc.gov)
  • 2002) Thus, even when given sufficient doses of atropine, patients may need artificial ventilation, sometimes for weeks. (cdc.gov)
  • Some cases of mild to moderate poisonings may improve with these doses of atropine. (cdc.gov)
  • A hospital stay may be needed for more doses of the medicines that reverse the effects of the drug. (medlineplus.gov)
  • Atropine inhibited WGE over the entire range of doses tested. (cdc.gov)
Acetylcholine5
  • Cholinergic blocking drugs are a group of drugs that block the action of acetylcholine (ACh), a neurotransmitter, in synapses of the cholinergic nervous system. (wikipedia.org)
  • Because this mechanism is relatively insensitive to drug action, the most important group of drugs that affect the neuromuscular junction act on (1) acetylcholine release, (2) acetylcholine receptors, or (3) the enzyme acetylcholinesterase (which normally inactivates acetylcholine to terminate muscle fibre contraction). (britannica.com)
  • There are a few drugs that facilitate acetylcholine release, including tetraethylammonium and 4-aminopyridine. (britannica.com)
  • Neuromuscular blocking drugs act on acetylcholine receptors and fall into two distinct groups: nondepolarizing (competitive) and depolarizing blocking agents. (britannica.com)
  • Competitive neuromuscular blocking drugs act as antagonists at acetylcholine receptors, reducing the effectiveness of acetylcholine in generating an end-plate potential . (britannica.com)
Parenteral2
  • If miosis (pupillary constriction) is due to direct conjunctival vapor exposure, it is relatively unresponsive to parenteral atropine. (cdc.gov)
  • Parenteral atropine is not generally recommended for those whose sole manifestation of toxicity is miosis (pupillary constriction). (cdc.gov)
Active ingredient1
  • The mydriatic effect was studied by the German chemist Friedlieb Ferdinand Runge (1795-1867), in which the active ingredient, atropine, was first discovered by Vaquelin in 1809 and was first isolated by Heinrich F. G. Mein in 1813. (wikipedia.org)
OINTMENT2
  • Apply Atropine ointment 1 to 3 times daily to treat mild to moderate ulcers of the cornea and anterior uveitis. (vetdepot.com)
  • Store Atropine Ointment at controlled room temperature, between 59 and 86 degrees F. Keep away from children and animals. (vetdepot.com)
Cholinesterase1
  • Do not use this product on animals simultaneously or within 30 days before or after treatment with or exposure to cholinesterase inhibiting drugs, pesticides, or similar chemicals. (drugs.com)
Adenosine1
  • But other intracellular messengers such as cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) are also involved ( see the section Principles of drug action ). (britannica.com)
Substances1
  • What Drugs, Substances, or Supplements Interact with Plendil? (rxlist.com)
Opioid1
  • Opioid or substituted drug addiction (Methadone, Buprenorphine. (who.int)
Drops1
  • The patient was admitted to the hospital and was administered hourly topical treatments of polyhexamethylene biguanide eye drops, hexamidine, and 1% atropine. (cdc.gov)
Diseases1
  • Two diseases we discussed could be treated in their beginning stages with these drugs. (proprofs.com)
Medications2
  • Do not use Atropine on animals with a known allergy to it or to similar medications. (vetdepot.com)
  • Turning to the main medications administered during CPR in newborns, the adrenaline was the drug of choice, followed by atropine, bicarbonate and dobutamine. (bvsalud.org)
Ephedrine2
  • Ephedrine and Pseudo-Ephedrine are called mixed acting drugs for what reason? (proprofs.com)
  • Ephedrine and Pseudo-Ephedrine are referred to as mixed acting drugs because they exhibit both antagonistic and stimulatory effects on their receptor simultaneously. (proprofs.com)
Ingredients1
  • Check labels on all medicines (e.g., cough-and-cold products, diet aids, nonsteroidal anti-inflammatory drugs or NSAIDs for pain/fever reduction) as they may contain ingredients that could increase your blood pressure. (rxlist.com)
Generic4
  • This active drug is also available as a generic medication. (medicalnewstoday.com)
  • A generic drug is an exact copy of the active drug in a brand-name medication. (medicalnewstoday.com)
  • The generic is considered to be as safe and effective as the original drug. (medicalnewstoday.com)
  • Typically, generic drugs are more cost-effective compared to their branded counterparts. (medindia.net)
Symptomatic3
  • If the patient is symptomatic, standard advanced cardiac life support (ACLS) guidelines for bradycardia, including the use of atropine and transcutaneous pacing, are indicated. (medscape.com)
  • Except for the use of atropine in selected cases of transient AV block, permanent cardiac pacing has replaced medical interventions in the treatment of patients with symptomatic, otherwise untreatable, AV block. (medscape.com)
  • Symptomatic patients should be treated with atropine and transcutaneous pacing. (medscape.com)
Dosage2
  • Clinical findings against which to titrate atropine dosage. (cdc.gov)
  • Here we describe an oral dosage form composed of distinct drug-polymer matrices which achieved week-long systemic drug levels of the antiretrovirals dolutegravir, rilpivirine and cabotegravir in a pig. (nature.com)
Cocaine1
  • The qualitative urinary toxicology screen detected opioids and cocaine, and the patient denied taking any other drugs. (bmj.com)
Effects14
  • Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. (drugs.com)
  • Mechanism by which atropine counters the effects of the cholinergic toxidrome. (cdc.gov)
  • Inform your doctor if you experience any of these side effects after using the drug. (northdrugstore.com)
  • Atropine can reduce the effects of cisapride. (nih.gov)
  • The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. (medicalnewstoday.com)
  • Both the loss of balance and dry mouth that you describe are potential side effects of atropine administration. (vetinfo.com)
  • These effects should only last until the drug is completely removed from the system. (vetinfo.com)
  • Your veterinarian can advise you on this and what to do to ease her symptoms of dry mouth until the effects of the drug completely disappear. (vetinfo.com)
  • The side effects of diphenoxylate drugs include dry mouth, bloating, and constipation . (healthline.com)
  • According to the literature, most of the effective drugs antagonize other effects of reserpine. (erowid.org)
  • Our Plendil Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
  • The effects of mediator modifying drugs, as well as an angiotensin converting enzyme inhibitor (captopril), a calcium channel blocking agent (TMB8) and capsaicin were tested. (cdc.gov)
  • If Navane is taken with certain other drugs, the effects of either could be increased, decreased, or altered. (online-family-doctor.com)
  • The effects of LSD and amphetamine differ from those of atropine and physostigmine in depending on mesencephalic or spinal connection. (erowid.org)
Breast milk1
  • It is not known whether this drug passes into breast milk. (rxlist.com)
Receptor2
  • Some drugs for the treatment of asthma block the binding of leukotrienes to their receptor. (britannica.com)
  • This dual action of the drugs on the receptor is what classifies them as mixed acting drugs. (proprofs.com)
Adverse3
  • If unable to avoid or use alternant drugs, closely monitor for increased adverse reactions. (medscape.com)
  • Please do not use this form to submit personal or patient medical information or to report adverse drug events. (medscape.com)
  • You are encouraged to report adverse drug event information to the FDA. (medscape.com)
Cardiac1
  • In addition, in patients who have denervated hearts (eg, patients who have undergone a cardiac transplant), atropine is also not likely to be effective. (medscape.com)
Allergic2
  • As with most drugs, some people can have an allergic reaction after taking Mestinon. (medicalnewstoday.com)
  • It isn't known whether allergic reactions occurred clinical trials of this drug or how often they may have happened. (medicalnewstoday.com)
Medicines1
  • Office for the Eastern Mediterranean, Cairo, Egypt (Correspondence to Zafar Mirza: [email protected]). 2WHO now uses the term medicines instead of drugs. (who.int)
Symptoms1
  • If you are using this drug for the first time and experience a hypersensitive reaction (symptoms are: facial flushness, swelling of the upper face, or trouble swallowing or breathing), consult your doctor immediately. (northdrugstore.com)
Treatment7
  • In the 1850s, atropine was used as antispasmodic in asthma treatment and as morphine antidote for its mydriatic effect. (wikipedia.org)
  • During treatment, avoid driving unless you are sure about how you react to the drug. (northdrugstore.com)
  • Before starting treatment, inform your doctor about all the drugs that you are taking, including all herbal and non-prescription drugs. (northdrugstore.com)
  • In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. (northdrugstore.com)
  • Immediate access to suitable equipment, drugs and staff for emergency treatment must be ensured because, rare cases of serious reactions, at times with a lethal outcome, have been reported after the use of local anaesthetics, even without a case history of individual hypersensitivity. (janusinfo.se)
  • An important rationale for studying weaning of pharmacological treatment for NOWS is that weaning represents the longest time interval of drug treatment. (bvsalud.org)
  • Hospitals will be able to use either morphine or methadone with the knowledge that we may find a positive treatment effect for both, one, or neither drugs. (bvsalud.org)
Receptors4
  • Atropine is not thought to have significant effect on nicotinic receptors, and thus does not counteract fasciculations, weakness, or flaccid paralysis. (cdc.gov)
  • Which drugs select α 1 receptors and indicate whether agonistically or antagonistically. (proprofs.com)
  • These drugs bind to α1 receptors and activate them, leading to vasoconstriction and increased blood pressure. (proprofs.com)
  • Why can this drug affect the heart rate by affecting alpha instead of beta receptors? (proprofs.com)
Heart rate2
Generics1
Brand1