Drug eruptions. Medical search. Frequent questions

HUSAVIK, Iceland (AP) - The Blue Lagoon geothermal spa - one of Iceland's biggest tourist attractions - closed temporarily as a swarm of earthquakes put the island nation's most populated region on alert for a possible volcanic eruption. (wivb.com)
People thought a volcanic eruption was about to happen. (wivb.com)
Iceland, which sits above a volcanic hotspot in the North Atlantic, averages an eruption every four to five years. (wivb.com)
Seismic activity in southwestern Iceland decreased in size and intensity on Monday, but the risk of a volcanic eruption remained significant, authorities said, after earthquakes and evidence of magma spreading underground in recent weeks. (ctvnews.ca)
The volcanic eruption in the South Pacific Kingdom of Tonga peaked on Jan. 15 with more explosive force than 100 simultaneous Hiroshima bombs, NASA scientists reported on Monday (Jan 24). (livescience.com)
It also makes Tonga the most powerful volcanic eruption seen on Earth in more than 30 years, since the eruption of Mount Pinatubo in 1991. (livescience.com)
Learn about the major types of volcanoes, the geological process behind eruptions, and where the most destructive volcanic eruption ever witnessed occurred. (nationalgeographic.com)
A 2020 explosion in Lebanon's port city of Beirut led to a southward-bound, high-velocity atmospheric wave that rivaled ones generated by volcanic eruptions. (scitechdaily.com)
FILE - Plumes of steam rise above White Island off the coast of Whakatane, New Zealand, on Dec. 11, 2019, following a volcanic eruption on Dec. 9. (wsav.com)
A trial of New Zealand tourism operators accused of safety breaches after 22 people died in a 2019 volcanic eruption ended Tuesday, Oct. 31, 2023, with the last remaining defendant being found guilty on one count. (wsav.com)
Yakima received over an inch of volcanic ash from the May 18 eruption. (cdc.gov)
Volcanic eruptions may release selenium in air. (cdc.gov)

Your health care provider can probably make a diagnosis of polymorphous light eruption based on a physical exam and your answers to questions. (mayoclinic.org)
If your skin reacts to ultraviolet (UV) radiation, you're considered sensitive to sunlight (photosensitive) and may have polymorphous light eruption or another light-induced disorder. (mayoclinic.org)
Treatment of polymorphous light eruption usually isn't needed because the rash usually goes away on its own within 10 days. (mayoclinic.org)
Your health care provider may suggest phototherapy to prevent seasonal episodes of polymorphous light eruption if you have disabling symptoms. (mayoclinic.org)
Etiology: Polymorphous light eruption (PMLE) is an acquired disease, but the etiology is not fully known. (medscape.com)
Cite this: Polymorphous Light Eruption - Medscape - Jun 01, 2008. (medscape.com)
Polymorphous light eruption (PLE) is a common skin rash that occurs due to sunlight exposure. (medicalnewstoday.com)
There was no sign of dermal oedema seen in polymorphous light eruption and no germinal follicle formation as would be observed in lymphocytoma cutis or cutaneous follicular centre cell lymphoma. (who.int)

In August 2022, a three-week eruption happened in the same area, followed by another in July of this year. (ctvnews.ca)
Compared to the peak pandemic years of 2020 and 2021, Canada experienced an uptick in prescription drug shortages in 2022 that Health Canada says has continued throughout 2023. (ctvnews.ca)
La Palma Eruption 2022 Follow-up. (hogueprophecy.com)

Some of the most severe and life-threatening examples of drug eruptions are erythema multiforme, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), hypersensitivity vasculitis, drug induced hypersensitivity syndrome (DIHS), erythroderma and acute generalized exanthematous pustulosis (AGEP). (wikipedia.org)

Using a combination of satellite and surface-based surveys, researchers calculated the explosive power of the volcano based on the amount of rock that was removed during the blast from the island of Hunga Tonga-Hunga Ha'apai where it sits, the apparent height of the eruption cloud and several other factors. (livescience.com)
NOAA's GOES West satellite captured the explosive eruption of the Hunga Tonga-Hunga Ha'apai volcano, located in the South Pacific Kingdom of Tonga. (livescience.com)
The Tonga volcano erupted violently on Jan. 15, several weeks after a series of smaller eruptions in late December 2021 shook the uninhabited island of Hunga Tonga-Hunga Ha'apai. (livescience.com)
Hunga Tonga-Hunga Ha'apai is located in region of the South Pacific that's jam-packed with volcanoes-some above the waves, some far below-that have a penchant for violent eruptions. (nationalgeographic.com)

Fixed drug eruption is a pruritic or burning, sharply circumscribed, round-to-oval patch with violaceous or dusky erythema. (aafp.org)

The most disruptive in recent times was the 2010 eruption of the Eyjafjallajokull volcano, which spewed huge clouds of ash into the atmosphere and led to widespread airspace closures over Europe. (wivb.com)
HAWAIʻI VOLCANOES NATIONAL PARK - Today, the Hawaiian Volcano Observatory noted intermittent spattering from the west vents in the summit crater, and SO2 rates were the lowest recorded since the eruption began. (bigislandvideonews.com)
The eruptions from the Klyuchevskaya Sopka volcano sent ash as high as 13 kilometers (8 miles) above sea level, officials said. (fourstateshomepage.com)
The eruption of Taal Volcano has caused ash fall to spread to nearby regions including CALABARZON, NCR, and Region 3. (dynadrug.com)
They found that the wave generated by the Beirut blast was slightly larger than a wave generated by the 2004 eruption of Asama Volcano in central Japan, and comparable to ones that followed other recent eruptions on Japanese islands. (scitechdaily.com)
White Island, the tip of an undersea volcano also known by its Indigenous Māori name Whakaari, was a popular tourist destination before the eruption. (wsav.com)
As I've mentioned, I will be giving a talk here at Denison on the EyjafjallajÃ¶kull eruption and how the events unfolded on the internet - specifically, I'm interested in the idea of the general public taking an active role in volcano monitoring. (scienceblogs.com)

Bullous fixed drug eruption mimicking toxic epidermal necrolysis due to a topical agent has not been previously reported. (aai.org.tr)
Here we describe a case of generalized bullous fixed drug eruption due to ibuprofen gel. (aai.org.tr)

Angioedema can also be drug-induced (most notably, by angiotensin converting enzyme inhibitors). (wikipedia.org)
There has been a report in the past of drug eruptions induced by angiotensin-converting enzyme inhibitors that resemble lymphocytic infiltrate (of Jessner-Kanof) [6]. (who.int)

The most common type of eruption is a morbilliform (resembling measles) or erythematous rash (approximately 90% of cases). (wikipedia.org)
Morbilliform eruption localized to striae has been described with clindamycin. (medscape.com)
Morbilliform drug eruption. (medscape.com)
Morbilliform drug eruption is the most common form of drug eruption . (dermnetnz.org)
A morbilliform skin rash in an adult is usually due to a drug. (dermnetnz.org)
Numerous other drugs have been reported to cause morbilliform drug eruptions, including herbal and natural therapies. (dermnetnz.org)
Morbilliform drug eruption is a form of allergic reaction. (dermnetnz.org)
What are the clinical features of morbilliform drug eruption? (dermnetnz.org)
On the first occasion, a morbilliform rash usually appears 1-2 weeks after starting the drug, but it may occur up to 1 week after stopping it. (dermnetnz.org)
It is very rare for a drug that has been taken for months or years to cause a morbilliform drug eruption. (dermnetnz.org)
Morbilliform drug eruption usually first appears on the trunk and then spreads to the limbs and neck. (dermnetnz.org)
In the early phase, it may not be possible to clinically distinguish an uncomplicated morbilliform eruption from other more serious cutaneous adverse reactions (SCAR). (dermnetnz.org)
How is morbilliform drug eruption diagnosed? (dermnetnz.org)

Repeated exposure to the offending drug may cause new lesions to develop in addition to "lighting up" the older hyperpigmented lesions. (medscape.com)
Several variants of fixed drug eruption have been described, based on their clinical features and the distribution of the lesions. (medscape.com)
[ 10 ] CD8 + effector/memory T cells play an important role in reactivation of lesions with re-exposure to the offending drug. (medscape.com)
Thus, when reexposure to the drug occurs, a more rapid response develops in the exact location of any prior lesions. (medscape.com)
On re-exposure to the causative (or related) drug, skin lesions appear within 1-3 days. (dermnetnz.org)
For the etiological evaluation of fixed drug eruption, topical provocation with patch testing on sites of previous lesions is frequently applied. (aai.org.tr)

Whereas Type B or hypersensitivity reactions, are often immune-mediated and reproducible with repeated exposure to normal dosages of a given drug. (wikipedia.org)
Unlike type A reactions, the mechanism of type B or hypersensitivity drug reactions is not fully elucidated. (wikipedia.org)
These severe cutaneous drug eruptions are categorized as hypersensitivity reactions and are immune-mediated. (wikipedia.org)
There are four types of hypersensitivity reactions and many drugs can induce one or more hypersensitivity reactions. (wikipedia.org)
Desensitization Drug hypersensitivity is an immune-mediated reaction to a drug. (msdmanuals.com)

Examples of common drugs causing drug eruptions are antibiotics and other antimicrobial drugs, sulfa drugs, nonsteroidal anti-inflammatory drugs (NSAIDs), biopharmaceuticals, chemotherapy agents, anticonvulsants and psychotropic drugs. (wikipedia.org)
Common examples include photodermatitis due to local NSAIDs (such as piroxicam) or due to antibiotics (such as minocycline), fixed drug eruption due to acetaminophen or NSAIDs (Ibuprofen), and the rash following ampicillin in cases of mononucleosis. (wikipedia.org)
The major categories of causative agents of fixed drug eruption include antibiotics, antiepileptics, nonsteroidal anti-inflammatory agents, sildenafil, and phenothiazines, although numerous other agents and certain foods such as cashews and licorice have also been reported as causative agents. (medscape.com)
[ 21 ] Fixed drug eruption may rarely be related to foods, including residual antibiotics in meat products and quinine contained in tonic water. (medscape.com)
Many drugs can trigger this allergic reaction , but antibiotics are the most common group. (dermnetnz.org)
They mainly affect people prescribed beta-lactam antibiotics ( penicillins , cephalosporins), sulfonamides, allopurinol, anti-epileptic drugs and nonsteroidal anti- inflammatory drugs ( NSAID ) . (dermnetnz.org)
Certain drugs (like antibiotics) can produce a skin rash as an unwanted side effect. (medicinenet.com)

However, they can mimic various other conditions, thus delaying diagnosis (for example, in drug-induced lupus erythematosus, or the acne-like rash caused by erlotinib). (wikipedia.org)
The typical amount of time it takes for a rash to appear after exposure to a drug can help categorize the type of reaction. (wikipedia.org)
The starting date of each new drug is documented together with the onset of the rash. (dermnetnz.org)
Severe cutaneous adverse reactions (SCARs) include Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug rash with eosinophilia and systemic symptoms (DRESS). (thedermspecs.com)

Sulfa refers to sulfonamides, known as sulfa drugs, while sulfite is commonly found in wine, processed food, and condiments. (healthline.com)
Sulfa drugs were the first successful treatment against bacterial infections in the 1930s. (healthline.com)

Drug Reaction with Eosinophilia and Systemic Symptoms usually occurs between 15 and 40 days after exposure. (wikipedia.org)
EM, the least severe of the disorders, is characterized by targetoid, edematous papules and/or plaques In EM, less than 10% of cases are drug-induced and patients typically present with a prodrome of flu-like symptoms prior to the skin eruption which classically affects the hands, feet, and limbs. (thedermspecs.com)

In medicine, a drug eruption is an adverse drug reaction of the skin. (wikipedia.org)
A drug-induced reaction should be considered in any patient who is taking medications and who suddenly develops a symmetric cutaneous eruption. (medscape.com)
Fixed drug eruption (FDE) is a type of cutaneous drug reaction that occurs at the same sites upon re-exposure to specific medications. (escholarship.org)
Because the reaction may not occur until several days or even weeks after first exposure to the drug, it is important to consider all new drugs and not only the one that has been most recently started. (msdmanuals.com)
If no substitute drug is available and if the reaction is a mild one, it might be necessary to continue the treatment under careful watch despite the reaction. (msdmanuals.com)
Distinguishing a mild versus a life-threatening reaction is challenging, yet critical in the management of drug allergies. (thedermspecs.com)
Cutaneous manifestations are frequently the earliest signs of a systemic drug allergy and can provide information on the severity and prognosis of an allergic reaction. (thedermspecs.com)
Fixed drug eruption is a common cutaneous reaction which may be seen in reaction to several medications. (aai.org.tr)

This unprecedented rise in pharmaceutical use has led to an increasing number of observed adverse drug reactions. (wikipedia.org)
There are two broad categories of adverse drug reactions. (wikipedia.org)
For example, the field of pharmacogenomics aims to prevent the occurrence of severe adverse drug reactions by analyzing a person's inherited genetic risk. (wikipedia.org)
The content of this database of side effects (adverse drug reactions) is intended for educational and scientific research purposes only. (embl.de)
Basically, it is a clinical reference guide to adverse drug reactions (ADRs), drug interactions and other safety information for prescription and over-the-counter medicines. (bmj.com)
An estimated 2-4% of hospital admissions are related to adverse drug reactions. (medscape.com)
These adverse drug reactions have a broad spectrum of clinical manifestations that can mimic those of other disease states, including both local and systemic conditions. (medscape.com)
The clinical patterns of adverse drug reactions of the oral cavity include xerostomia, swelling, nonspecific ulceration, vesiculobullous or ulcerative mucositis that mimics other disease states, nonspecific vesiculoulcerative mucositis, pigmentation, gingival enlargement, and medication-related osteonecrosis of the jaws. (medscape.com)

Ibuprofen is the drug of choice for mild to moderate pain. (medscape.com)

While fixed drug eruptions are uncommon with general anesthesia, propofol has been implicated in causing a drug eruption on the penis. (medscape.com)

Eruptions can occur frequently with a certain drug (for example, with phenytoin), or be very rare (for example, Sweet's syndrome following the administration of colony-stimulating factors). (wikipedia.org)
Will there be an eruption and if so, what sort of damage will occur? (ctvnews.ca)
Rarely, cases of serum sickness-like reactions can occur around 10 days after a sulfa drug treatment begins. (healthline.com)

Most drug-induced cutaneous reactions are mild and disappear when the offending drug is withdrawn. (wikipedia.org)
Type A reactions are known side effects of a drug that are largely predictable and are called, pharmatoxicologic. (wikipedia.org)
Drug reactions have characteristic timing. (wikipedia.org)
these reactions normally resolve with hyperpigmentation and may recur at the same site with reexposure to the drug. (medscape.com)
Adverse reactions to medications are common and often manifest as a cutaneous eruption. (medscape.com)
Adverse cutaneous reactions caused by ingestion, parenteral use, or local application of a drug. (embl.de)
Types of Drug Reactions and. (msdmanuals.com)
Drugs can cause multiple skin eruptions and reactions. (msdmanuals.com)
Other drug reactions are classified by lesion type. (msdmanuals.com)
Sensitivity can be definitively established only by rechallenge with the drug, which may be hazardous and unethical in patients who have had severe reactions. (msdmanuals.com)
Most drug reactions resolve when drugs are stopped and require no further therapy. (msdmanuals.com)
More research is needed, as some of the rashes reported in COVID-19 patients resemble drug reactions. (medicinenet.com)
Cutaneous reactions are the most frequently occurring adverse reactions to drugs. (thedermspecs.com)
Numerous risk factors predispose patients to severe cutaneous drug reactions, including immunosuppression (especially infection with human immunodeficiency virus) or mononucleosis, female gender, number of drugs being taken, and elderly age. (thedermspecs.com)
thus, incidence rates for specific drugs are unknown and most of the facts available on drug-specific reactions have been extrapolated from reports in the human literature. (petmd.com)
Some types of drug reactions appear to have a familial basis. (petmd.com)
If the diagnosis is Stevens - Johnson syndrome (SJS), or toxic epidermal necrolysis (TEN), both potentially fatal drug based skin reactions, your dog will need to be treated on an inpatient basis. (petmd.com)
Not all drugs that contain sulfonamides cause reactions in all people. (healthline.com)
Mucocutaneous eruptions are often central to these untoward reactions, and an ever-expanding list of medications is linked to pathologic reactions in the oral and perioral region. (medscape.com)

In 2021, the Food and Drug Administration approved 50 new drugs, but 24 will not be described here because they would probably not be used in pregnancy. (medscape.com)

If hives are caused by a drug, that drug should be avoided in the future. (medicinenet.com)

Hallmark: The initial eruption consists of an itchy, acute facial or forearm dermatitis with edematous papules and vesicles (Weston, Lane, & Morelli, 2002), all of which are on sun-exposed areas. (medscape.com)

For example, Acute generalized exanthematous pustulosis usually occurs within 4 days of starting the culprit drug. (wikipedia.org)

The company also is accused of hundreds of record-keeping violations and of not submitting reports of its distribution transactions to the U.S. Drug Enforcement Administration, including those involving opioids, from May 2017 to July 2018, officials said. (wkrg.com)
2017). Drug allergy. (healthline.com)

The actual frequency may be higher than current estimates, owing to the availability of a variety of over-the-counter medications and nutritional supplements that are known to elicit fixed drug eruptions. (medscape.com)

As such, there are clinical examples of inherited genetic alleles that are known to predict drug hypersensitivities and for which diagnostic testing is available. (wikipedia.org)
Drug eruptions are diagnosed mainly from the medical history and clinical examination. (wikipedia.org)
Cutaneous drug eruptions cover a spectrum of diseases and clinical signs. (petmd.com)

To identify the possible causative drug , a drug calendar, including all prescribed and over-the counter products, may be helpful. (dermnetnz.org)
The most common causative drugs were antimicrobials and anti-epileptic drugs. (thedermspecs.com)

Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. (drugs.com)

Frequently these medications are taken intermittently and include non-steroidal anti-inflammatory drugs (pyrazolone derivatives, paracetamol, naproxen, oxicams and mefenamic acid), sulfonamides, and trimethoprim are frequent offenders. (acadderm.com)

It produces a red scaling often itchy eruption that characteristically affects the scalp , forehead, brows, cheeks, and external ears. (medicinenet.com)

A detailed history is often required for diagnosis, including recent use of over-the-counter drugs. (msdmanuals.com)

The Icelandic Meteorological Office said on Monday there was a 'significant likelihood' of an eruption in coming days on or just off the Reykjanes peninsula near the capital Reykjavik, despite the size and intensity of earthquakes decreasing. (ctvnews.ca)
I never knew how many eruptions and earthquakes happen worldwide, as troubleshooting and thinking outside of the box is what I am trained to do trying to link geological events is a lot of fun. (scienceblogs.com)

Satellites saw the Tonga eruption column rise halfway to space on Jan. 15. (livescience.com)
That makes the Tonga eruption potentially hundreds of times more explosive than the atomic bomb that the United States dropped on Hiroshima, Japan in August 1945, which is estimated to have exploded with 15 kilotons (15,000 tons) of energy. (livescience.com)

The prevalence of drug eruptions has been reported to range from 2-5% for inpatients and greater than 1% for outpatients. (medscape.com)
Treatment regimens should take into account the most recent official treatment guidelines (e.g. those of the WHO) and local information on the prevalence of resistance to antimalarial drugs. (who.int)

Certain drugs are less likely to cause drug eruptions (rates estimated to be ≤3 per 1000 patients exposed). (wikipedia.org)
Occasionally, patch testing can be helpful in patients with fixed drug eruptions. (msdmanuals.com)
Careful attention should be paid to measures designed to foster adherence and to ensure that patients take the drugs as prescribed. (cdc.gov)

However, the explosive Jan. 15 eruption - which sent a column of steam rising halfway to space - was far more violent than a typical Surtseyan eruption, Garvin said. (livescience.com)
This creates a lot of magma that tends to be sticky and filled with gas-a potent recipe for explosive eruptions. (nationalgeographic.com)

Anatomy4

Diseases15

Chemicals and Drugs2

Phenomena and Processes2

Disciplines and Occupations1

Volcanic12

Polymorphous8

20223

Examples of drug eruptions1

Hunga Tonga-Hunga Ha'apai4

Erythema1

Volcano7

Bullous2

Angiotensin converting2

Morbilliform13

Lesions6

Hypersensitivity5

Antibiotics7

Rash4

Sulfa drugs2

Symptoms2

Reaction8

Adverse drug reac8

Ibuprofen1

Uncommon1

Occur3

Reactions19

20211

Hives1

Dermatitis1

Acute1

20172

Elicit1

Clinical3

Causative2

Discontinuation1

Sulfonamides1

Scalp1

Diagnosis1

Earthquakes2

Tonga2

Prevalence2

Patients3

Explosive2