• The United States is in the grip of an epidemic of prescription drug overdoses. (cdc.gov)
  • Deaths from drug overdoses are the number one cause of injury death in the US. (cdc.gov)
  • Drug overdoses alone now top annual death rates from car crashes and gun violence. (rwjf.org)
  • p>Officials in Manchester, New Hampshire, launched Safe Stations to reduce drug addiction and opioid-related overdoses by connecting people with treatment at fire stations. (rwjf.org)
  • In 2020, the CDC estimated that nearly 3 million people in the U.S. were living with OUD and more than 65,000 people died by opioid overdose, of whom more than 15,000 were heroin overdoses. (wikipedia.org)
  • A 2017 National Safety Council survey found that 70% of employers reported suffering the negative effects of prescription drug misuse, noting positive drug tests, absenteeism, injuries, accidents, and overdoses [vii] . (cdc.gov)
  • Synthetic opioid use is booming, the United Nations said on Wednesday, in a worldwide drug report that shows rising deaths in the United States from overdoses and a 'crisis' of Tramadol use emerging in parts of Africa. (drugs-and-users.org)
  • Drug overdoses have really reached epidemic proportions in North America,' UNODC research chief Angela Me said. (drugs-and-users.org)
  • According to the CDC, more than 100,000 people died of drug overdoses in the United States during the 12-month period May 2020 to April 2021, reflecting a new record high. (medscape.com)
  • Opioids make up about 90 percent of all fatal overdoses in the state. (baltimoresun.com)
  • Health officials had gone on the offensive and spent millions of federal and state dollars to bring down opioid-related overdoses, which have claimed more than 2,000 Marylanders in each of the past three years. (baltimoresun.com)
  • Statement of purpose In the US, over 130 lives are lost from opioid-related drug overdoses each day. (bmj.com)
  • Last year there were approximately 8,000 drug overdoses in our state, and 636 Mainers died - a tragic record," Collins said in a statement announcing funding for the programs. (centralmaine.com)
  • Since the 1990s, when the amount of opioids prescribed to patients began to grow, the number of overdoses and deaths from prescription opioids has also increased. (cdc.gov)
  • From 1999 to 2020, more than 263,000 people died in the United States from overdoses involving prescription opioids. (cdc.gov)
  • Opioid overdoses increased 30 percent from July 2016 through September 2017 in 52 areas in 45 states. (investmentwatchblog.com)
  • The Midwestern region saw opioid overdoses increased 70 percent from July 2016 through September 2017. (investmentwatchblog.com)
  • Opioid overdoses in large cities increased by 54 percent in 16 states. (investmentwatchblog.com)
  • Over 52,000 people died of drug overdoses in 2015-and 63% of these involved opioids. (gao.gov)
  • This is reflected in the increasing age of those in drug treatment and those dying from opioid overdoses. (europa.eu)
  • Background: Prescription sedatives are efficient in the treatment of anxiety and sleeping disorders, but are associated with a risk of misuse and dependence, as well as an increased risk of accidents, injuries and overdoses, both in the general population and especially in individuals with other substance misuse. (lu.se)
  • The legislation will expand availability of treatment for opioid use disorder in emergency departments and access to naloxone, the life-saving drug that can reverse overdoses, to community-based organizations. (michigan.gov)
  • This epidemic touches every area of our state and we are losing nearly five Michiganders every single day to opioid overdoses," said Lieutenant Governor Gilchrist. (michigan.gov)
  • In 2018 and 2019, Michigan saw a moderate decline in the number of opioid-related overdoses. (michigan.gov)
  • In 2017, opioid-related overdoses caused 47,600 deaths, an average of 130 every day. (cdc.gov)
  • Drug overdose death disparities are widening at the same time as a record-breaking 92,000 lives were lost to drug overdoses during 2020. (cdc.gov)
  • America's growing opioid epidemic and untreated serious mental illness is having a devastating impact on communities nationwide. (rwjf.org)
  • The opioid overdose epidemic continues to claim lives across the country with a record 47,600 overdose deaths in 2017 [i] . (cdc.gov)
  • The entire nation is struggling with the opioid epidemic. (cdc.gov)
  • As we continue to develop effective solutions to the opioid epidemic, employers can take the following steps to contribute to the prevention and treatment of OUD. (cdc.gov)
  • Please share with us in the comment section below how your workplace has been impacted by or dealt with the opioid epidemic. (cdc.gov)
  • While this epidemic has received public attention in recent years, Me pointed out that there is another opioid crisis unfolding in African and Middle Eastern countries like Egypt, Nigeria and Ghana, where abuse of the pain medication Tramadol has emerged as a problem. (drugs-and-users.org)
  • [ 2 ] Although primarily due to COVID, the opioid overdose epidemic is also a contributing factor. (medscape.com)
  • Increases in acute hepatitis C virus infection related to a growing opioid epidemic and associated injection drug use, United States, 2004 to 2014. (jamanetwork.com)
  • Both COVID-19 and the opioid epidemic have disrupted health care. (deloitte.com)
  • Before the COVID-19 pandemic, health care in the United States was already grappling with another crisis: the opioid epidemic. (deloitte.com)
  • As leaders continue to seek ways to address the many challenges the COVID-19 pandemic and the opioid epidemic bring, they must navigate a complicated web of social, economic, and financial implications and questions related to the crises. (deloitte.com)
  • Health care has already started to respond to the seismic shifts patients and communities are experiencing as a result of the confluence of the COVID-19 pandemic and the opioid epidemic, implementing new technology solutions and innovative strategies to deliver care to patients, maintain continuity of operations, and mitigate the spread of COVID-19. (deloitte.com)
  • Significance Strategies to address the opioid epidemic have primarily focused on prevention of overdose deaths. (bmj.com)
  • It's not just the opioid epidemic. (vox.com)
  • Researchers are still puzzling over why we're seeing these increases, but many have pointed to economic despair and the opioid epidemic concentrated in these areas of the country. (vox.com)
  • HHS officials told GAO that as of August 2017, the department was in the process of finalizing its plans to evaluate its efforts to address the opioid epidemic. (gao.gov)
  • HHS officials told GAO that they are still working with the contractor to finalize the evaluation approach and that it will focus on whether HHS's efforts to address the opioid epidemic have been implemented as intended. (gao.gov)
  • In 2020, the challenges of the COVID-19 global pandemic, such as increased social isolation and decreased access to treatment services, exacerbated the already deadly drug overdose epidemic. (michigan.gov)
  • Michigan hospitals are committed to being part of the solution to the opioid epidemic that has impacted every community in Michigan," said Brian Peters, Michigan Health & Hospital Association CEO. (michigan.gov)
  • Availability and use of illicit fentanyls are still the major drivers of overdose deaths and the current rise in stimulant-related deaths appears entwined with the ongoing opioid epidemic. (lww.com)
  • Governments to "strengthen the prevention and treatment of substance abuse", and a range of other targets are of particular relevance to drug control, particularly target 3.3 on ending the AIDS epidemic and combating hepatitis, target 3.4 on prevention and treatment of noncommunicable diseases and 1 See Official Records of the Economic and Social Council, 2009, Supplement No. 8 (E/2009/28), chap. (who.int)
  • With increasing intravenous drug abuse (IVDA) amid the opioid epidemic, the risk factor profile may be shifting. (bvsalud.org)
  • CONCLUSIONS: These findings strongly suggest that the national increase in acute HCV infection is related to the country's opioid epidemic and associated increases in IDU. (cdc.gov)
  • Prescription drugs are now involved in more overdose deaths than heroin and cocaine combined. (cdc.gov)
  • Most of these deaths are related to the misuse of prescription opioids and heroin. (cdc.gov)
  • Women's deaths from opioid overdose are increasing substantially. (cdc.gov)
  • These epidemics have a particularly daunting impact on rural communities, where the rate of opioid-related overdose deaths is 45 percent higher than in metro-area counties. (rwjf.org)
  • High rates of opioid overdose deaths have occurred in industries with high injury rates and physically demanding working conditions such as construction, mining, or fishing [ii] , [iii] . (cdc.gov)
  • The rapid rise in opioid-related overdose deaths in recent years is driven by greatly increased exposure to illicitly manufactured fentanyl and fentanyl analogues. (hivguidelines.org)
  • Synthetic opioids, primarily fentanyl, caused nearly two-thirds (64%) of all drug overdose deaths in the same 12-month period, up 49% from the year before. (medscape.com)
  • Drug overdose deaths in the United States, 1999-2019. (jamanetwork.com)
  • State data shows that opioid-related deaths, as well as fatalities from all other substances, ticked up in the first three months of 2020. (baltimoresun.com)
  • There were 561 opioid-related deaths in the three months ending March 31, according to data from the state's Opioid Operations Command Center and the Department of Health. (baltimoresun.com)
  • Fentanyl, a powerful synthetic opioid that has replaced much of the street heroin, accounts for most of the opioid deaths. (baltimoresun.com)
  • The report showed that deaths related to heroin and prescription painkillers, also opioids, dropped more than fentanyl-related deaths grew. (baltimoresun.com)
  • Officials said many people use drug combinations, leading to the overall increase in opioid fatalities, but didn't fully explain how the deaths were recorded. (baltimoresun.com)
  • Those who treat substance use disorders say they expect deaths to continue rising. (baltimoresun.com)
  • Opioid-related overdose deaths dropped in nine jurisdictions, including Baltimore City, which has long had the most fatalities in the state. (baltimoresun.com)
  • Accurate and prompt diagnosis of opioid use disorders (OUD) may contribute substantially to prevention of overdose deaths. (bmj.com)
  • In England, UK, hospital admissions caused by bacterial infections associated with opioid use have increased annually since 2012, after 9 years of decline, mirroring trends in overdose deaths. (cdc.gov)
  • In the United Kingdom, opioid overdose deaths have increased substantially, linked to increasing purity of street heroin and an aging cohort of persons who inject drugs (PWID) ( 1 ). (cdc.gov)
  • States like Minnesota and Massachusetts lead the nation with some of the lowest reported rates of cardiovascular-related deaths (roughly 200 per 100,000), whereas states like Arkansas and Oklahoma still report more than 300 for every 100,000 deaths. (vox.com)
  • Overdose deaths involving prescription opioids nearly increased by five times from 1999 to 2020 1 . (cdc.gov)
  • In response to the high rate of opioid-related addiction and deaths in Colorado, the Colorado General Assembly created the Opioid and Other Substance Use Disorders Study . (colorado.gov)
  • Substance use disorders (SUDs) and overdose deaths have reached unprecedented levels despite considerable efforts to develop pharmacotherapies for their treatment and prevention. (iasp-pain.org)
  • With support from MACPAC, AcademyHealth's Evidence-Informed State Health Policy Institute and the University of Pittsburgh are conducting a pilot project with four Medicaid Outcomes Distributed Research Network (MODRN) participating State-University Partnership Learning Network (SUPLN) partnerships to explore the level of concurrent use of benzodiazepines and opioids among Medicaid beneficiaries, a risk factor for poisoning deaths. (academyhealth.org)
  • To make matters worse, opioid-related deaths in Ontario have increased since 2019 , or prior to the pandemic, according to Public Health Ontario (PHO). (healthydebate.ca)
  • However, there are ways to help address the crisis and reduce opioid-related deaths related to low back pain. (healthydebate.ca)
  • In 2019, total drug overdose deaths - which includes opioids and unspecified substances - decreased by 9.4 percent to 2,354 deaths and opioid-related deaths fell by 13.2 percent to 1,768 deaths. (michigan.gov)
  • Provisional 2020 data shows an increase in total drug overdose deaths in Michigan. (michigan.gov)
  • Deaths declined for all opioids (2%), prescription opioids (14%), and heroin (4%), yet increased for synthetic opioids (10%) in this time period. (lww.com)
  • The overall downward signal was driven by declines in deaths related to prescription opioids. (lww.com)
  • Title : Illicit drug use, illicit drug use disorders, and drug overdose deaths in metropolitan and nonmetropolitan areas -- United States Personal Author(s) : Mack, Karin A.;Jones, Christopher M.;Ballesteros, Michael F. (cdc.gov)
  • Rates of overdose deaths involving synthetic opioids other than methadone, which includes fentanyl and fentanyl analogs, increased over 22% from 2020 to 2021. (cdc.gov)
  • The rate of overdose deaths involving synthetic opioids in 2021 was nearly 22 times the rate in 2013. (cdc.gov)
  • Nearly 71,000 drug overdose deaths involved synthetic opioids other than methadone in 2021. (cdc.gov)
  • The latest provisional drug overdose death counts suggest overdose deaths accelerated during the COVID-19 pandemic. (cdc.gov)
  • Psychoactive drug use is responsible for more than 400 000 deaths per year. (who.int)
  • Most of the national response to the crisis focuses on preventing overdose deaths, on providing the best treatment for people with opioid addiction, and on changing prescription practices to prevent new cases of opioid overuse. (cdc.gov)
  • In just one year, overdose death rates (number of drug overdose deaths per 100,000 people) increased 44% for Black people and 39% for American Indian and Alaska Native (AI/AN) people. (cdc.gov)
  • Comprehensive, community-based prevention and response efforts should incorporate proven, culturally responsive actions that address disparities in drug overdose deaths and the inequities that contribute to them. (cdc.gov)
  • OUD can involve the use of illegal opioids (for example, heroin) or prescription opioids (for example, oxycodone). (ada.gov)
  • In the United States, most heroin users begin by using prescription opioids that may also be bought illegally. (wikipedia.org)
  • The use of opioids - an umbrella term for drugs ranging from opium and derivatives such as heroin to synthetics like Fentanyl and Tramadol - was up 56 percent from 2016 with 53 million users worldwide. (drugs-and-users.org)
  • Co-occurring attention deficit hyperactivity disorder symptoms in adults affected by heroin dependence: patients characteristics and treatment needs. (jamanetwork.com)
  • In addition, some 591,000 suffered from a heroin use disorder. (investmentwatchblog.com)
  • An estimated 4 to 6 percent who misuse prescription opioids transition to heroin. (investmentwatchblog.com)
  • About 80 percent of people who use heroin first misused prescription opioids. (investmentwatchblog.com)
  • 2 It is sold through illegal drug markets for its heroin-like effect. (cdc.gov)
  • More than 2 million people have an opioid misuse disorder, with over a quarter of a million using heroin. (cdc.gov)
  • The print ad failed to disclose the potential for fatal overdose in this vulnerable patient population, and, as OPDP noted, opioid dependence and misuse is a significant public health concern and national crisis affecting millions of people. (agg.com)
  • However, it is likely that the following factors combined to elevate this to a Warning Letter: (1) omission of the risk of potentially fatal overdose, (2) the opioid crisis, (3) this is a REMS drug, (4) OPDP's prior advisory comments, and (5) the sponsor's response to the letter from the review division. (agg.com)
  • You can learn more about this topic at The Americans with Disabilities Act and the Opioid Crisis . (ada.gov)
  • Learn more about how OUD can meet the ADA's definition of disability at The Americans with Disabilities Act and the Opioid Crisis . (ada.gov)
  • Learn more about what current illegal drug use means at The Americans with Disabilities Act and the Opioid Crisis . (ada.gov)
  • The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis. (jamanetwork.com)
  • By supporting prevention, treatment, and recovery programs, this funding will expand vital assistance to Mainers who are struggling with addiction and help combat the opioid crisis. (centralmaine.com)
  • The most troublesome story in America today is the escalating opioid overdose crisis. (investmentwatchblog.com)
  • The guidance reflects the Trump Administration's ongoing commitment to combatting the nation's opioid crisis. (cms.gov)
  • Leveraging the existing MODRN infrastructure, which currently involves many of those states hardest hit by the opioid crisis, this research project enables the MODRN-OUD project to expand its research scope to include a focus on other controlled substances, and substance use disorders with the potential to extend beyond the current participants to include those states within other regions grappling with a different drug addiction crisis, such as, methamphetamines. (academyhealth.org)
  • Unfortunately, it also added fuel to the opioid crisis, particularly in treating chronic back pain. (healthydebate.ca)
  • Some of these fatalities are pandemic-related, while others are indicative of the ongoing opioid crisis. (healthydebate.ca)
  • The opioid crisis has devastated communities and destroyed the lives of far too many all across our state," said Representative Witwer. (michigan.gov)
  • The COVID-19 pandemic of 2020-2021 has over-shadowed another escalating crisis, that of drug overdose. (lww.com)
  • Can ergonomics programs help solve the opioid crisis? (cdc.gov)
  • Much attention is being paid to the opioid crisis in the United States, and rightfully so. (cdc.gov)
  • The decline in life expectancy in the U.S. between 2014 and 2016 as reported by CDC is due at least in part to the opioid crisis. (cdc.gov)
  • Each number related to the crisis represents a heart-wrenching web of loss that could have been avoided. (cdc.gov)
  • Buprenorphine is one of three FDA-approved medications for the treatment of OUD and reduces the risk of overdose, illicit opioid use, and infectious disease transmission that can accompany injection drug use. (pewtrusts.org)
  • Sublingual buprenorphine-naloxone and extended-release injection naltrexone are effective treatments, with distinct mechanisms, for opioid use disorder. (nih.gov)
  • In a multisite 24-week randomized comparative-effectiveness trial of assignment to buprenorphine-naloxone (N=287) compared with extended-release naltrexone (N=283) comprising inpatients planning to initiate medication treatment for opioid use disorder, 50 demographic and clinical characteristics were examined as moderators of the effect of medication assignment on relapse to regular opioid use and failure to initiate medication. (nih.gov)
  • Among patients with opioid use disorder admitted to inpatient treatment, homelessness, parole and probation status, medication preference, and factors likely to influence tolerability of medication initiation may be important in matching patients to buprenorphine or extended-release naltrexone. (nih.gov)
  • People with an opioid use disorder are often treated with opioid replacement therapy using methadone or buprenorphine. (wikipedia.org)
  • Three drugs commonly used in MAT are methadone, buprenorphine, and naltrexone. (cdc.gov)
  • Methadone and buprenorphine are the only two opioids that are indicated for the management of both pain and opioid-related drug addiction. (nshealth.ca)
  • Handbook of Methadone Prescribing and Buprenorphine Therapy is an invaluable guide to the safe use of these opioids. (nshealth.ca)
  • Buprenorphine Metabolism and Drug-Drug Interactions -- 14. (nshealth.ca)
  • Buprenorphine and Opioid Rotation -- 16. (nshealth.ca)
  • Those in treatment for their disorder with the drug buprenorphine still could get prescriptions via a telehealth appointment with a doctor, but programs offering the widely used treatment methadone are in-person only. (baltimoresun.com)
  • Buprenorphine/naloxone is used in the treatment of Opioid Use Disorder and belongs to the drug class narcotic analgesic combinations . (drugs.com)
  • For those who are addicted to or misuse opioids, medication-assisted treatment (MAT)-behavioral therapy combined with medication (such as buprenorphine)-can help. (gao.gov)
  • The Department of Health and Human Services implemented a number of efforts to improve access to MAT for opioids, such as grant programs for rural primary care settings and allowing additional providers to prescribe buprenorphine. (gao.gov)
  • HHS has implemented five key efforts since 2015 that focus on expanding access to MAT for opioid use disorders-four grant programs that focus on expanding access to MAT in various settings (including rural primary care practices and health centers) and regulatory changes that expand treatment capacity by increasing patient limits for buprenorphine prescribers and allowing nurse practitioners and physician assistants to prescribe buprenorphine. (gao.gov)
  • Suboxone (buprenorphine/naloxone) is a drug prescribed to treat opioid use disorder. (healthline.com)
  • Probuphine is the first subdermal implant for the maintenance treatment of opioid use disorder designed to provide continuous, non-fluctuating, blood levels of buprenorphine for up to six months following a single outpatient office-based procedure. (cadth.ca)
  • In May 2016, the US Food and Drug Administration (FDA) approved Probuphine implants for the maintenance treatment of opioid dependence in patients who have achieved and sustained prolonged clinical stability on low-to-moderate doses of a transmucosal buprenorphine-containing product (i.e., doses of no more than 8 mg per day of Subutex or Suboxone sublingual tablet or generic equivalent). (cadth.ca)
  • One phase III, double-blind, double-dummy active-controlled trial showed Probuphine to be noninferior to sublingual buprenorphine for the primary outcome of at least four of six months with no illicit opioid use among patients with opioid use disorder previously stabilized on a low-to-moderate dose (≤ 8 mg/day) of sublingual buprenorphine. (cadth.ca)
  • It is unclear how the requirement for supplemental therapy with sublingual buprenorphine demonstrated in the phase III trials could impact the ability of Probuphine to mitigate misuse and accidental pediatric exposure, particularly if use is limited to a subpopulation of patients with clinically stable opioid use disorder. (cadth.ca)
  • Ensure continuity in provision of harm reduction services, including needle and syringe exchange and opioid substitution treatment programmes using methadone or buprenorphine. (who.int)
  • Fewer Medicaid patients had buprenorphine prescriptions (17.8% vs 27.3%) despite similar rates of known substance-related disorders. (cdc.gov)
  • For many people, OUD is a disability under the ADA's definition because it is a drug addiction that substantially limits a major life activity. (ada.gov)
  • An employer fires an employee because it finds out the employee completed treatment for a previous addiction to prescription opioids. (ada.gov)
  • Addiction and dependence are important components of opioid use disorder. (wikipedia.org)
  • Justin Brokken learned he qualified for a new program that's becoming the standard for how to treat opioid addiction in hospital emergency rooms across Alaska - from Petersburg to Anchorage. (alaskapublic.org)
  • Up until last summer, the emergency department was limited in how it could treat people with opioid addiction. (alaskapublic.org)
  • Now, the city has the money, and it will be used to get people into treatment," said At-Large Councilor Courtney Gary-Allen, a leader of a city task force working on how to help people escape addiction and substance use disorder. (centralmaine.com)
  • We are suffering from a spate of drug addiction and mental health issues. (investmentwatchblog.com)
  • The European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) is the leading authority on illicit drugs in the European Union. (europa.eu)
  • Thousands of Michigan families in nearly every community in our state have seen the devastating effects of opioid addiction and abuse. (michigan.gov)
  • On December 2, 2019, the Food and Drug Administration's Office of Prescription Drug Promotion (OPDP) sent a Warning Letter to the sponsor of a drug that is indicated for the prevention of relapse to opioid dependence, following opioid detoxification. (agg.com)
  • Published in: Drug and Alcohol Dependence, Volume 177, Supplement C (August 2017), Pages 307-314. (rand.org)
  • Treating Pain in Patients Receiving Methadone Maintenance for Opioid Dependence -- 4. (nshealth.ca)
  • The American Psychiatric Association (APA) guidelines identify the following treatment modalities as effective strategies for managing opioid dependence and withdrawal. (medscape.com)
  • Influence of attention deficit hyperactivity disorder and conduct disorder on opioid dependence severity and psychiatric comorbidity in chronic methadone-maintained patients. (jamanetwork.com)
  • Suboxone is prescribed for adults to treat dependence * on opioid medications , which is also called opioid use disorder . (healthline.com)
  • Dependence is when your body gets used to a drug and needs it for you to function as usual. (healthline.com)
  • The present thesis aims to investigate prescription sedative use and misuse in two kinds of samples - in the general population, with focus on its association with subjective health and quality life, and in the subpopulation of individuals with opioid dependence, with focus on treatment outcome in opioid maintenance treatment and mortality. (lu.se)
  • Materials and Methods: Prescription sedative misuse was studied in three Swedish datasets: 1) a general population survey (n =22,095), 2) a clinical pilot study for the treatment of opioid dependence (n =44 and 36, for the original study and the follow-up study, respectively), and 3) a national register-based study of individuals in opioid maintenance treatment ( n= 4,501). (lu.se)
  • In individuals with opioid dependence, benzodiazepine misuse was found to be negatively associated with retention in opioid maintenance treatment. (lu.se)
  • Prescription of sedatives was associated with mortality in individuals with opioid dependence, including associations between prescriptions of 'z-drug' hypnotics and pregabalin and overdose death. (lu.se)
  • In individuals with opioid dependence, clinicians also need to be aware of the increased risk of overdose and non-overdose death, as well as possible negative effects on treatment outcome, that come with sedative use and misuse. (lu.se)
  • Opioid use disorder (also known as opioid dependence), defined as a problematic pattern of opioid use leading to clinically significant impairment or distress, is a growing public health concern in Canada that is associated with significant morbidity and mortality. (cadth.ca)
  • Substance use disorders include a number of conditions, including hazardous and harmful use and substance dependence, which is a disorder of regulation of the use of a psychoactive substance arising from repeated or continuous use of the substance. (who.int)
  • UN's drug agency says 30 percent more people used drugs in 2017 than in 2009. (drugs-and-users.org)
  • The number of people using drugs in 2017, about 271 million, was 30 percent higher than in 2009, the report from the UN Office on Drugs and Crime (UNODC) found. (drugs-and-users.org)
  • Increased drug use has had health effects, the report said, with 35 million people in 2017 suffering from drug-related disorders requiring treatment up from an earlier estimate of 30.5 million. (drugs-and-users.org)
  • Opiods were responsible for two thirds of the 585,000 people who died in 2017 as a result of drug use. (drugs-and-users.org)
  • More than 47,000 people died from lethal opioid doses in the United States in 2017, and nearly 4,000 people in Canada. (drugs-and-users.org)
  • The most widely used drug globally continued to be cannabis , with an estimated 188 million people having used the drug in 2017. (drugs-and-users.org)
  • Presented to the Opioid and Other Substance Use Disorders Interim Study Committee at its September 2017 meeting. (colorado.gov)
  • In addition, a 2017 Canadian guideline for opioid therapy and chronic noncancer pain recommends co-ordinated multidisciplinary collaborations between physicians and other health-care professionals, such as chiropractors. (healthydebate.ca)
  • This memorandum provides an overview of the 2017 membership of the Opioid and Other Substance Use Disorders Interim Study Committee, the origin and charge of the committee, bill request deadlines and procedures, and information regarding committee staff and the committee website. (colorado.gov)
  • As of this writing, the most recent formal US Centers for Disease Control and Prevention (CDC) report on overdose reveals a slight overall decline in opioid-related fatalities from 2017 to 2018 [1] . (lww.com)
  • Process measures included quarterly physician visits, any opioid use disorder pharmacotherapy, continuous pharmacotherapy, psychosocial treatment, Hepatitis B/C and HIV screening, and no prescriptions for benzodiazepines or opioids. (rand.org)
  • Among individuals with opioid use disorders, not being prescribed opioids or benzodiazepines, receipt of any psychosocial treatment and quarterly physician visits were significantly associated with lower mortality at both 12 and 24 months, but Hepatitis and HIV screening, and measures related to opioid use disorder pharmacotherapy were not. (rand.org)
  • Management of opioid withdrawal includes the use of other opioids, benzodiazepines and alpha-2 adrenergic receptor antagonist, clonidine. (nih.gov)
  • The problematic use of other drugs, for example benzodiazepines, is increasingly also causing concern. (europa.eu)
  • Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death. (drugs.com)
  • During the 2019 session, the Colorado General Assembly considered several pieces of legislation related to state health programs, behavioral and mental health, reducing health care costs, hospital transparency, and advance directives. (colorado.gov)
  • Data from the "World Drug Report 2019" show that 271 million people worldwide aged 15‒64 used an illegal drug once in the past year, while 35 million were suffering from substance use disorders. (who.int)
  • Under the new benefit, state Medicaid programs must cover all drugs and biologicals approved or licensed by the FDA to treat opioid use disorders, including methadone, along with related counseling services and behavioral therapies. (cms.gov)
  • Suboxone is usually taken long term to treat opioid use disorder . (healthline.com)
  • An employer fires an employee because it mistakenly believes the employee has OUD, simply because the employee uses opioids legally prescribed by a doctor to treat pain from an injury. (ada.gov)
  • Act fast in the case of a fentanyl-related … use disorder is a medical condition that can affect anyone who uses opioids. (wisconsin.gov)
  • When the COVID-19 pandemic struck in early 2020, the federal government began allowing people to receive opioid use disorder (OUD) treatment services remotely, or via telehealth, by interacting with doctors and other providers over the internet and by phone. (pewtrusts.org)
  • For example, a 2020 Pain Medicine journal study reported patients with spinal pain who saw a chiropractor were half as likely to fill an opioid prescription compared to those who did not. (healthydebate.ca)
  • In 2020, the latest year in which data is available, … Carry NARCAN® NARCAN® is the opioid overdose reversal drug. (wisconsin.gov)
  • Between March 2020 and April 4, Miranda reports, "OSHA received about 14,000 coronavirus-related complaints in 2020 and opened only about 1,900 for inspection. (wholefoodsmagazine.com)
  • The powerful analgesic Fentanyl and similar substances are the main killers among drug users in that region. (drugs-and-users.org)
  • Therefore, the aims of this study were to evaluate the effectiveness of Maraviroc, a CCR5 antagonist, and AMD3100, a CXCR4 antagonist, to alter 1) the self-administration of fentanyl, an opioid, and cocaine, a stimulant, using a food versus drug choice procedure and 2) the analgesic effects of fentanyl in a radiant heat assay. (iasp-pain.org)
  • Management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. (oncologynurseadvisor.com)
  • According to the PI, patients treated with the drug are likely to have reduced tolerance to opioids (i.e., patients may respond to lower doses of opioids than previously used). (agg.com)
  • Cases of opioid overdose with fatal outcomes have been reported in patients at the end of a dosing interval, after missing a dose, or after discontinuing treatment. (agg.com)
  • Attempts by patients to overcome the blockade effect of the drug may also lead to fatal overdose. (agg.com)
  • Emerging research shows that allowing telehealth-based OUD treatment has helped patients initiate and remain on medication treatment, and also that these patients stayed in treatment and abstained from illicit opioids at rates comparable to individuals who received care in person. (pewtrusts.org)
  • Retrospective cohort study of patients with opioid use disorders who received care from the Veterans Administration between October 2006 and September 2007. (rand.org)
  • This is the first study to show an association between process measures and mortality in patients with opioid use disorders and provides initial evidence for their use as quality measures. (rand.org)
  • This guideline was developed by the New York State Department of Health AIDS Institute (NYSDOH AI) to inform clinicians who do not specialize in substance use treatment of the currently available and effective strategies for treating adult patients with opioid use disorder (OUD). (hivguidelines.org)
  • Patients with opioid use disorders frequently relapse and present with intoxication. (medscape.com)
  • Some hospitals in Alaska are changing the way they treat patients with opioid use disorder. (alaskapublic.org)
  • But it wasn't necessarily the right medicines to be giving patients with acute opioid withdrawal," Geldhof said. (alaskapublic.org)
  • After the pandemic-related distancing orders, programs stopped taking new patients and distribution of the overdose remedy naloxone stopped, said Dr. Michael Fingerhood, who treats substance use disorders at Johns Hopkins Bayview Medical Center and is an associate professor of medicine and public health at Johns Hopkins University. (baltimoresun.com)
  • Fingerhood said many programs are again accepting patients, but he expects the numbers from April, May and June in the heart of the pandemic-related shutdowns to be worse than the previous months. (baltimoresun.com)
  • Previous studies have identified patients who use drugs as those with a drug-related diagnosis in any diagnostic field ( 7 , 8 ). (cdc.gov)
  • We identified patients with "injecting-related" infections as those with a relevant infection in the primary diagnostic field and "mental and behavioral disorders due to opioid use" (F11*) in any other diagnostic field, because most PWID in the United Kingdom inject an opioid ( 9 ). (cdc.gov)
  • Patients with injecting-related infections were younger and more likely to live in deprived neighborhoods, and a minority were female ( Table ). (cdc.gov)
  • Alvimopan is contraindicated in opioid tolerant patients (ie, those who have taken therapeutic doses of opioids for >7 consecutive days immediately prior to taking alvimopan). (medscape.com)
  • Patients recently exposed to opioids are expected to be more sensitive to the effects of alvimopan and therefore may experience abdominal pain, nausea and vomiting, and diarrhea. (medscape.com)
  • Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. (medscape.com)
  • It all started with pharmaceutical companies assuring the medical community that patients would not become addicted to prescription opioids in the 1990s. (investmentwatchblog.com)
  • Roughly 21 to 29 percent of patients prescribed opioids for chronic pain misuse them. (investmentwatchblog.com)
  • The guidance issued today provides information to state Medicaid programs about a new mandatory Medicaid benefit added under the Substance Use-Disorder Prevention that Promotes Opioid Recovery and Treatment for Patients and Communities Act (SUPPORT Act). (cms.gov)
  • Although many patients are prescribed opioids for pain, a 2016 systematic review and meta-analysis found that although opioid medications provide modest, short-term relief for people with chronic back pain, evidence of long-term efficacy is lacking. (healthydebate.ca)
  • To best support patients in reducing their pain and risk of opioid dependency, interprofessional collaboration is imperative. (healthydebate.ca)
  • ABSTRAL ® is contraindicated in opioid non-tolerant patients ( 1 ) and in management of acute or postoperative pain, including headache/migraines ( 4 , 5.1 ). (drugs.com)
  • ABSTRAL ® is an opioid agonist indicated for the management of breakthrough pain in cancer patients 18 years of age and older who are already receiving, and who are tolerant to, around-the-clock opioid therapy for their underlying persistent cancer pain ( 1 ). (drugs.com)
  • Patients must remain on around-the- clock opioids while taking ABSTRAL. (drugs.com)
  • Not for use in opioid non-tolerant patients. (drugs.com)
  • Patients must require and use around-the-clock opioids when taking ABSTRAL ( 1 ). (drugs.com)
  • Doctors give about 20% of their patients opioids or narcotics. (trans4mind.com)
  • Cognitive-behavioral interventions may reduce pain and pain-related disability and help patients cope. (msdmanuals.com)
  • Two patients were initiated on medication-assisted treatment for opioid use disorder. (bvsalud.org)
  • One month prior to overdose, 24.5% of Medicaid and 8.6% of commercially insured patients had opioid prescriptions. (cdc.gov)
  • A higher proportion of Medicaid patients had non-substance-related comorbidities. (cdc.gov)
  • Outpatient settings are of particular importance for the growing cohort of young, commercially insured patients with opioid use disorders. (cdc.gov)
  • Fatalities related to cocaine, alcohol, benzodiazepine and methamphetamines also increased, in addition to those related to opioids. (baltimoresun.com)
  • In an effort to reduce the prevalence of opioid misuse and the fatalities associated with it, the Department of Health and Human Services (HHS) established a goal to expand access to medication-assisted treatment (MAT). (gao.gov)
  • Opioid use is the leading cause of overdose-related fatalities in the United States. (clevelandleader.com)
  • Fentanyl-associated fatalities among illicit drug users in Wayne County, Michigan (July 2005-May 2006). (cdc.gov)
  • Many of the other substances were used in combination with opioids, the state report says. (baltimoresun.com)
  • With support from the Medicaid and CHIP Payment & Access Commission, AcademyHealth's Evidence-Informed State Health Policy Institute, in collaboration with the University of Pittsburgh, is exploring the use of non-opioid controlled substances and the treatment of non-opioid substance use disorders. (academyhealth.org)
  • Different target groups have a responsibility to steer clear of substance use throughout this pandemic and beyond, and to help others do the same, and get the help they need, in case they are using substances or suffering from substance use disorders. (who.int)
  • Nevertheless, actions to reduce drug use through enforcement of the prohibition of non-medical use of internationally controlled substances and related law enforcement strategies have largely dominated the implementation of national drug control strategies to date. (who.int)
  • Similarly, Health Quality Ontario (HQO) suggests that making better use of non-medical treatments to manage acute and chronic pain will reduce the number of people who use opioids in the long-term. (healthydebate.ca)
  • In older people who use opioids, the physical ageing process may be accelerated by the cumulative effects of polydrug use and poor health over many years. (europa.eu)
  • Opioid use disorder (OUD) is associated with substantial morbidity and mortality for women, especially during the perinatal period. (biomedcentral.com)
  • OBJECTIVE: Pregnancy-related infective endocarditis (IE) caries a high risk of morbidity and mortality. (bvsalud.org)
  • In 2016, nearly 60,000 people were arrested in Taiwan for drug-related offenses, a more than 10 percent increase from the previous year, according to data collected by Taiwan News . (hightimes.com)
  • Dr. Haegerich is co-author of the 2016 CDC Guidelines for Prescribing Opioids for Chronic Pain. (cdc.gov)
  • The 2016 special session of the United Nations General Assembly on the world drug problem will be convened at United Nations headquarters in New York from 19 to 21 April 2016. (who.int)
  • opiates and opioids MME of common opioids Long-term opioid use occurs in about 4% of people following their use for trauma or surgery-related pain. (wikipedia.org)
  • Management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. (renalandurologynews.com)
  • Medication-assisted treatment* (MAT) has been effective for many people with opioid use disorder (OUD), allowing them to regain control of their OUD [v] , [vi] . (cdc.gov)
  • A new resource from NIOSH, " Workplace Solutions: Medication-Assisted Treatment for Opioid Use Disorder " provides general information about MAT and information for employers wishing to assist or support workers with OUD. (cdc.gov)
  • Medication-assisted treatment (MAT) is an evidence-based treatment that consists of the administration of medications and related behavioral therapies. (cms.gov)
  • This guide highlights the use of medication-assisted treatment (MAT) for opioid use disorder in drug courts. (samhsa.gov)
  • This manual offers guidelines for medication-assisted treatment for people, particularly veterans, living with post-traumatic stress disorder and co-occurring opioid use disorders. (samhsa.gov)
  • Individuals with opioid use disorder (OUD) struggle to get effective care: Of 2 million Americans with the illness, only 26% receive treatment. (pewtrusts.org)
  • Individuals with opioid use disorders have high rates of mortality relative to the general population. (rand.org)
  • 1-3 Individuals with opioid use disorder are at greater risk for incarceration, blood-borne infections, and fatal overdose. (cadth.ca)
  • These facilities are regulated by the federal Drug Enforcement Administration and Substance Abuse and Mental Health Services Administration, as well as stage agencies, and are the only treatment facilities legally able to offer all three medications for opioid use disorder (OUD). (pewtrusts.org)
  • MAT uses medications approved by the U.S. Food and Drug Administration (FDA) in combination with counseling and behavioral therapies to treat OUD involving misuse of prescription and/or illicit opioids. (cdc.gov)
  • The medications reduce the cravings for, and the euphoria (extreme pleasure) experienced from, opioids. (cdc.gov)
  • They also lower the risk of the dangerous side effects of opioids [v]. Some medications may also reduce the risk of subsequent overdose. (cdc.gov)
  • Educate workers about how drugs impair work activities, including driving, and encourage them to notify their employers if they are taking medications that may affect their ability to work safely so that a safe solution can be determined. (cdc.gov)
  • Coadministration of apalutamide, a strong CYP3A4 inducer, with drugs that are CYP3A4 substrates can result in lower exposure to these medications. (medscape.com)
  • Avoid or substitute another drug for these medications when possible. (medscape.com)
  • Two bills will expand availability of medications for opioid use disorder (MOUD) in emergency departments and improve referral to treatment. (michigan.gov)
  • Consider possible misleading symptoms, such as amphetamine-related hyperthermia or being afebrile, due to misuse of medications, when assessing for COVID-19 symptoms among people who use drugs. (who.int)
  • Medications and therapies typically depend on the patient's response to pain and usually include an epidural catheter, intravenous narcotics for breakthrough pain, patient-controlled analgesia (PCA), and selective use of nonsteroidal anti-inflammatory drugs (NSAIDs). (medscape.com)
  • The report's data not only showed a higher prevalence of the use of opioids in Africa, Asia, Europe and North America it also said the use of cannabis in North America, South America and Asia rose compared with 2009. (drugs-and-users.org)
  • The estimated prevalence of perinatal opioid use disorder (OUD) grew from 1.5 to 6.5 per 1000 delivery hospitalizations from 1999 to 2014 [ 4 ]. (biomedcentral.com)
  • People with substance use disorders are particularly vulnerable to COVID-19 infection and worse treatment outcomes because they are more likely to have a higher prevalence of co-morbid health conditions (e.g. mental disorders, HIV, TB, hepatitis, cardiovascular, liver, respiratory and kidney diseases) and often share other risk factors, such as under/malnutrition, physical inactivity, alcohol and tobacco use. (who.int)
  • Consider prescribing naloxone based on risk factors for overdose (eg, history of opioid use disorder, prior opioid overdose, household members or other close contacts at risk for accidental ingestion or overdose). (renalandurologynews.com)
  • The DSM-5 guidelines for the diagnosis of opioid use disorder require that the individual has a significant impairment or distress related to opioid uses. (wikipedia.org)
  • Individuals with OUD have a pattern of opioid use that leads to significant issues, such as health problems and difficulty meeting major responsibilities at home, work, or school. (ada.gov)
  • Induction of anesthesia is accomplished by using high doses of opioid. (medscape.com)
  • Continuing to use opioids despite experiencing persistent or recurrent social or interpersonal problems caused or exacerbated by the effects of opioids. (medscape.com)
  • Chemoattractant cytokines ('chemokines') are immune system messengers that can alter the therapeutic and abuse-related effects of opioids and stimulants. (iasp-pain.org)
  • Opioid use disorder (OUD) is a substance use disorder characterized by cravings for opioids, continued use despite physical and/or psychological deterioration, increased tolerance with use, and withdrawal symptoms after discontinuing opioids. (wikipedia.org)
  • Opioid withdrawal symptoms in neonates can be assessed by using easily available scoring systems, although these need to be validated for different populations. (nih.gov)
  • Withdrawal, as manifested by either the characteristic opioid withdrawal syndrome, or taking opioids to relieve or avoid withdrawal symptoms. (medscape.com)
  • Withdrawal symptoms are side effects caused by suddenly stopping a drug. (healthline.com)
  • If you need to stop the drug, your doctor will gradually reduce your dose to help you avoid side effects, such as opioid withdrawal symptoms . (healthline.com)
  • In 2011, the American Academy of Pediatrics published a clinical report detailing the recommended guidelines for the management of neonatal drug withdrawal. (medscape.com)
  • Neonatal opioid withdrawal syndrome. (renalandurologynews.com)
  • potential neonatal opioid withdrawal syndrome during prolonged use. (renalandurologynews.com)
  • Prolonged use of ABSTRAL ® during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated. (drugs.com)
  • If prolonged opioid use is required in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available ( 5.8 ). (drugs.com)
  • 4 In addition, babies born to mothers who used opioids during pregnancy are at increased risk for neonatal opioid withdrawal syndrome, a life-threatening condition if not promptly recognized. (cadth.ca)
  • This scoping review analyzed the many and varied factors contributing to the recent rise in opioid overdose death rates among Black Americans. (asam.org)
  • Those involved in the criminal justice system have high rates of opioid use and are disproportionately low income , which means the majority of them are eligible for Medicaid coverage. (pswc2010.org)
  • Signs and symptoms of opioid intoxication include: Decreased perception of pain Euphoria Confusion Desire to sleep Nausea Constipation Miosis (pupil constriction) Bradycardia (slow heart rate) Hypotension (low blood pressure) Hypokinesis (slowed movement) Head nodding Slurred speech Hypothermia (low body temperature) Signs and symptoms of opioid overdose include, but are not limited to: Pin-point pupils may occur. (wikipedia.org)
  • Symptoms of opioid abuse can be categorized by physical state. (medscape.com)
  • These results show an important pathway into child maltreatment and the need for well-supported programs for women who use illicit drugs during pregnancy and long-term support after birth of the child. (medscape.com)
  • Background Cardiovascular dysfunction and hypertension can persist postpartum following hypertensive disorders of pregnancy (HDPs). (bvsalud.org)
  • BACKGROUND: Adverse pregnancy outcomes (APOs), hypertensive disorders of pregnancy, gestational diabetes mellitus, and preterm birth are associated with ischemic heart disease in later life. (bvsalud.org)
  • CONCLUSION: These findings confirm that IVDA is a growing risk factor for pregnancy-related IE. (bvsalud.org)
  • KEY POINTS: · Intravenous drug use was the most common risk factor for IE in pregnancy. (bvsalud.org)
  • As people across the country continue to practice physical distancing, individuals with OUD may have more difficulty coping with stress and opioid cravings , which could place them at an increased risk for relapse . (pewtrusts.org)
  • Adverse clinical effects associated with the use of opioids in neonates include respiratory depression, chest wall rigidity, urinary retention, and decreased gastrointestinal motility. (nih.gov)
  • COVID-19 has created challenges that in many cases have disproportionately or uniquely impacted individuals with OUD, including worsening mental and behavioral health needs, exacerbating pre-existing issues related to social determinants of health, and increasing or causing new challenges to accessing. (deloitte.com)
  • Behavioral health is a term used to encompass a number of facets that impact a person's well-being, including but not limited to mental health, substance use disorder (SUD), adverse life events or stressors, and individual behaviors that impact mental and physical health. (deloitte.com)
  • Like other behavioral disorders, these are polygenically inherited and each gene accounts for only a small per cent of the variance. (biopsychiatry.com)
  • Pharmaceutical fentanyl is a synthetic opioid approved for treating severe pain, typically advanced cancer pain. (cdc.gov)
  • It may come as a surprise that back pain has been reported in more than half of regular opioid users . (healthydebate.ca)
  • Results from two phase III, double-blind, placebo-controlled trials showed Probuphine to be superior to placebo implants in reducing illicit opioid use during a six-month treatment period in new entrants to therapy. (cadth.ca)
  • Twin epidemics: the surging rise of methamphetamine use in chronic opioid users. (jamanetwork.com)
  • I am delighted to welcome you to today's COCA call: CDC Guidelines for Prescribing Opioids for Chronic Pain. (cdc.gov)
  • COCA is excited to partner with CDC's National Center for Injury Prevention and Control to offer this call series on CDC Guidelines for Prescribing Opioids for Chronic pain. (cdc.gov)
  • Now, a new study in the Journal of General Internal Medicine concludes that receiving treatment that is not drug-based can reduce the likelihood of such outcomes in veterans with chronic pain. (medicalnewstoday.com)
  • As well, in its Opioid Prescribing for Chronic Pain standard, HQO recommends spinal manipulation in conjunction with an active physical therapy or exercise program. (healthydebate.ca)
  • Antidepressants, antiseizure drugs, and other central nervous system (CNS)-active drugs may also be used for chronic or neuropathic pain and are first-line therapy for some conditions. (msdmanuals.com)
  • Causes include chronic disorders. (msdmanuals.com)
  • Overdose due to illicit synthetic opioids (e.g. fentanyl and fentanyl analogs) continues to rise in the US both preceding and during the COVID-19 pandemic. (lww.com)
  • synthetic opioids-related (predominately illicit fentanyl and fentanyl analogs) overdose rose dramatically 2014 to present [2▪▪,3,4▪] . (lww.com)
  • OUD is a specific kind of substance use disorder. (ada.gov)
  • Nearly 10 million adults have serious mental illness, and 20 million have a substance use disorder. (rwjf.org)
  • Nearly nine in 10 people with a substance use disorder (88%) and more than one in three people with serious mental illness (35%) did not receive treatment for their conditions. (rwjf.org)
  • Untreated serious mental illness and substance use disorder contribute to rising rates of incarceration, homelessness, and use of emergency services, straining local criminal justice systems, law enforcement, first responders, and community and public health resources. (rwjf.org)
  • p>The authors report that many local programs targeting untreated substance use disorder and serious mental illness are not well understood beyond their communities. (rwjf.org)
  • AUGUSTA - City councilors voted recently to accept $263,000 in federal grant funding to start a project aimed at connecting people with substance use disorder with treatment programs, when they are ready for help . (centralmaine.com)
  • The grant funds could be used to pay staff members to run the program, officials said, and to provide transportation to help people get into substance use disorder treatment programs. (centralmaine.com)
  • Increasing access to proven treatment for all people who have substance use disorder(s) is a critical part of their care and recovery. (cdc.gov)
  • Harm reduction services can include naloxone, fentanyl test strips, and referral to substance use disorder treatment. (cdc.gov)
  • Syringe services programs can serve as a valuable way to reach people who inject drugs and provide them with overdose prevention education and opportunities to link to substance use disorder treatment. (cdc.gov)
  • METHODS: We calculated the annual incidence rate and demographic and risk characteristics of reported cases of acute HCV infection using surveillance data from 2004 to 2014 and the annual percentage of admissions to substance use disorder treatment facilities reporting IDU for the same time period by type of drug injected and demographic characteristics. (cdc.gov)
  • Learn about care and prevention approaches and the federal response to this disorder. (cdc.gov)
  • Her expertise lies in the area of prescription drug overdose prevention, motor vehicle injury prevention, evaluation, implementation science and evidence-based practice guidelines. (cdc.gov)
  • The Family Violence Prevention and Services Grants Program assists state agencies, territories and Indian Tribes in the provision of shelter to victims of family violence and their dependents, and for related services, such as emergency transportation and child care. (hhs.gov)
  • For example, the Political Declaration supports a rebalancing of international policy on drugs, to focus on public health, prevention, treatment and care, and economic, social and cultural measures. (who.int)
  • Effective prevention measures have the potential to promote health and social wellbeing, and lower the human and societal costs of drug use, particularly by focusing on preventing the initiation and continuation of drug use by children, adolescents and young people. (who.int)
  • OBJECTIVES: To compare US trends in rates of injection drug use (IDU), specifically opioid injection, with national trends in the incidence of acute HCV infection to assess whether these events correlated over time. (cdc.gov)
  • Significant increases in opioid injection mirrored those for reported cases of acute HCV infection among demographic subgroups. (cdc.gov)