Chemicals and Drugs
LoperamideAntidiarrhealsThiorphan
HYDROCHLORIDEImodiumDiarrheaMedicationOpioidActive ingredientDoses of loperamideEffect of loperamideTablet2023SymptomsAdverseDoseOverdoseDosageConstipationEffluxStoolsMedicationsPrescriptionConcentrationsAntimicrobialInteractionsInteractionCapsuleStrengthsSlowsMicroscopic colitisRatsAllergic reactionTravelersCYP3A4AntibioticOpioidsDiphenoxylateAbuseNauseaInflammatoryArrhythmiasPharmacistBreast milkAntidiarrhoeal2021Pharmacists2016LiquidStomachCapsulesSubstrateSupplementsIngredientsInteractPathwaysMedicinesSide effectsAddictionMisuse
HYDROCHLORIDE5
  • Product categories of Catharitic & Antidiarrheic Drugs , we are specialized manufacturers from China, Catharitic Drugs , Antidiarrheic Drugs suppliers/factory, wholesale high-quality products of Loperamide Hydrochloride Capsule Catharitic Drugs R & D and manufacturing, we have the perfect after-sales service and technical support. (g-housemedicines.com)
  • Loperamide Hydrochloride Capsule BP 2mg as antidiarrheal, used to control the symptoms of acute and chronic diarrhea. (g-housemedicines.com)
  • A rat constipation model was established by gavage administration of loperamide hydrochloride. (rsc.org)
  • 8 The stimulatory effects of bromelain on gastrointestinal motility disorder was evaluated by establishing a constipation rat model via gavage administration of loperamide hydrochloride. (rsc.org)
  • The active ingredient is loperamide hydrochloride. (drfelix.co.uk)
Imodium17
Diarrhea32
  • Nonprescription (over-the-counter) loperamide is used to control acute diarrhea (loose stools that come on suddenly and usually lasts less than 2 weeks), including travelers' diarrhea. (nih.gov)
  • If you are taking loperamide for acute diarrhea and your symptoms get worse or if your diarrhea lasts longer than 48 hours, stop taking this medication and call your doctor. (nih.gov)
  • Loperamide is used to treat diarrhea. (everydayhealth.com)
  • Ask your doctor before using loperamide to treat diarrhea caused by taking an antibiotic (Clostridium difficile). (everydayhealth.com)
  • Stop taking loperamide and call your doctor if you still have diarrhea after 2 days of treatment, or if you also have stomach bloating. (everydayhealth.com)
  • patients with diarrhea, an antidiarrheal agent such as loperamide is a drug which slows gut transit. (nih.gov)
  • Loperamide is effective for the treatment of a number of types of diarrhea. (wikipedia.org)
  • Off-label uses for loperamide also include chemotherapy-induced diarrhea, especially related to irinotecan use. (wikipedia.org)
  • Loperamide should not be used as the primary treatment in cases of bloody diarrhea, acute exacerbation of ulcerative colitis, or bacterial enterocolitis. (wikipedia.org)
  • If a suspicion exists of diarrhea associated with organisms that can penetrate the intestinal walls, such as E. coli O157:H7 or Salmonella, loperamide is contraindicated as a primary treatment. (wikipedia.org)
  • The study reported that the use of loperamide should be contraindicated in children who are under 3, systemically ill, malnourished, moderately dehydrated, or have bloody diarrhea. (wikipedia.org)
  • No definitive etiology has been determined for microscopic colitis (MC), but evidence indicates that drug consumption may trigger underlying inflammatory factors in the colon of affected individuals, whereas other agents may exacerbate diarrhea in patients with idiopathic microscopic colitis. (medscape.com)
  • 16] Although many drugs, either alone or in combination, may cause diarrhea as an adverse effect,[17] nonsteroidal anti-inflammatory drugs (NSAIDs) show a strong trend (P = 0.057) toward increasing the risk of collagenous colitis (CC), and rechallenge has been shown to cause recurrence of collagenous colitis. (medscape.com)
  • Loperamide has been available over the counter for treating diarrhea for many years. (pharmacytimes.com)
  • Patients self-treating diarrhea and loperamide abusers report taking daily doses of 25 to more than 200 mg. (pharmacytimes.com)
  • 6-8 Although patients taking approved doses of loperamide for a short episode of diarrhea are unlikely to suffer adverse reactions from these interactions, patients taking excess doses are at much greater risk for adverse events. (pharmacytimes.com)
  • If usual doses of loperamide are not effective in relieving diarrhea, patients should be advised to see their health care provider. (pharmacytimes.com)
  • Loperamide is available OTC for the symptomatic treatment of diarrhea. (jabfm.org)
  • Antidiarrheic Drugs refer to the drug control diarrhea. (g-housemedicines.com)
  • Antimicrobial drug treatment of travelers' diarrhea is known to increase the risk for colonization with extended-spectrum β-lactamase-producing Enterobacteriaceae . (cdc.gov)
  • It is also used to treat ongoing diarrhea in people with inflammatory bowel disease .Loperamide treats only the symptoms, not the cause of the diarrhea (such as infection). (webmd.com)
  • Loperamide may be used occasionally for acute management of severe diarrhea but avoid chronic use. (medscape.com)
  • What you are looking at is loperamide, a drug used to treat diarrhea. (smithsonianmag.com)
  • Also that year, the Upstate New York Poison Center handled 59 cases of people who abused or overdosed on anti-diarrhea medication containing loperamide, an opioid. (upstate.edu)
  • Diarrhea is common after treatment with chemotherapy drugs or with targeted therapy drugs (and after radiation therapy). (merckmanuals.com)
  • Loperamide, a common anti-diarrhea medication, could help treat core symptoms associated with autism spectrum disorder. (neurosciencenews.com)
  • WARNING: Irinotecan can cause severe diarrhea, both early in treatment and 24 hours or more after receiving this drug. (patientassistance.com)
  • Your doctor will give you loperamide for this form of diarrhea. (patientassistance.com)
  • Report immediately any diarrhea occurring within the first day of the drug injection. (patientassistance.com)
  • This later form of diarrhea is treated immediately with loperamide as directed by your doctor. (patientassistance.com)
  • Use of laxatives should be avoided since this drug may cause diarrhea. (patientassistance.com)
  • Severity and frequency of diarrhea generally decreased following one to two cycles, and was managed with loperamide or dose reduction. (lilly.com)
Medication13
  • Loperamide may also be used for purposes not listed in this medication guide. (everydayhealth.com)
  • Loperamide is available as a generic medication. (wikipedia.org)
  • Drugs that reduce inflammatory changes at the level of the colonic mucosa may be needed in a subset of patients with colitis who fail to respond to antidiarrheal medication. (medscape.com)
  • Loperamide may in like manner be used for purposes not recorded as a piece of this medication guide. (medicinesmexico.com.mx)
  • The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. (drugs.com)
  • Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. (drugs.com)
  • Our nation's growing population of opioid-addicted patients is seeking alternative drug sources with prescription opioid medication abuse being limited by new legislation and regulations," he said. (cbsnews.com)
  • Empaveli is a biologic drug that's available only as a brand-name medication. (medicalnewstoday.com)
  • Drugs made from chemicals can have generics (exact copies of the active drug in the brand-name medication). (medicalnewstoday.com)
  • The preferred medication to help treat diarrhoea given out by general practitioners is Loperamide. (hda-online.org.uk)
  • Pricing is displayed for LOPERAMIDE , a generic medication. (americaspharmacy.com)
  • Loperamide, a phenylpiperidine derivative [ 1 ], is an anti-diarrhoeal medication which acts selectively on peripheral μ-opioid receptors [ 2 ]. (walshmedicalmedia.com)
  • Tell your doctor of all nonprescription and prescription medication you may use, especially of: other anti-cancer drugs, laxatives, "water pills" (diuretics), drugs that treat diabetes. (patientassistance.com)
Opioid14
  • The efflux transporter P-glycoprotein, a member of the adenosine triphosphate-binding cassette superfamily, is a major determinant of the pharmacokinetics and pharmacodynamics of the opioid loperamide, a well-recognized antidiarrheal agent. (nih.gov)
  • Combination of a δ-opioid Receptor Agonist and Loperamide Produces Peripherally-mediated Analgesic Synergy in Mice. (iasp-pain.org)
  • Therefore, the authors hypothesized that loperamide, a highly efficacious μ-opioid receptor agonist that is excluded from the central nervous system, and oxymorphindole, a δ-opioid receptor agonist that was shown to synergize with morphine spinally, would synergistically reverse complete Freund's adjuvant-induced hyperalgesia. (iasp-pain.org)
  • Loperamide is a unique opioid in that it usually only demonstrates peripheral activity, slowing gastrointestinal motility without the central nervous system (CNS) effects seen with other opiates. (pharmacytimes.com)
  • The antidiarrheal loperamide has had a recent, drastic increase in off-label use as an alternative treatment for symptoms of opioid withdrawal. (jabfm.org)
  • Loperamide at higher doses has found a reputation as an alternative to standard opioid withdrawal therapy. (jabfm.org)
  • The opioid epidemic is fueled both by the abuse of street drugs such as heroin and the addiction to prescription painkillers. (upstate.edu)
  • Willie Eggleston blames over-prescribing of opioid pain medications such as oxycodone and aggressive ad campaigns from drug manufacturers. (upstate.edu)
  • Emergency responders are equipped with a drug called naloxone that can reverse opioid effects. (upstate.edu)
  • By binding to the μ-opioid receptors in the gut wall, loperamide decreases peristalsis and fluid secretion, resulting in longer gastrointestinal transit time and increased absorption of fluids and electrolytes from the gastrointestinal tract [ 1 ]. (walshmedicalmedia.com)
  • The drug activates the μ-opioid receptor, helping to improve social behaviors. (neurosciencenews.com)
  • Antidiarrheal drug loperamide, a weak synthetic opioid, was significantly associated with ventricular arrhythmia (proportional reporting ratio [PRR] 3.2, 95% CI 3.0-3.4), with 37% of the 1,008 FDA Adverse Event Reporting System (FAERS) reports involving death. (medpagetoday.com)
  • As both readily available drugs have come to be used to curb opioid cravings at large doses, their hazards have taken on urgency amid the crackdown on prescription opioid access. (medpagetoday.com)
  • [1,2,3] Because opioid abuse can result in a myriad of neurologic, cardiovascular, musculoskeletal, and pulmonary complications, [4] healthcare providers must be prepared to diagnose and treat the potentially fatal conditions that can be precipitated by opioids, especially as they occur through IV drug abuse (IVDA)/injection drug use (IDU). (medscape.com)
Active ingredient3
Doses of loperamide2
  • The reported plasma concentrations following usual doses of loperamide range from 0.2 to 1.2 ng/mL. (pharmacytimes.com)
  • In November 2016, the US Food & Drug Administration released a statement highlighting the potential heart effects and risk of death with high doses of loperamide. (jabfm.org)
Effect of loperamide2
  • Some researchers have posed the question as to whether the antimotility effect of loperamide, involving prolonged passage through the gastrointestinal tract, would, in fact, increase the risk for colonization (data not shown). (cdc.gov)
  • erdafitinib will increase the level or effect of loperamide by P-glycoprotein (MDR1) efflux transporter. (medscape.com)
Tablet3
  • Loperamide comes as a tablet, capsule, and as a suspension or solution (liquid) to take by mouth. (nih.gov)
  • The loperamide chewable tablet must be chewed before swallowing. (everydayhealth.com)
  • Gemfibrozil oral tablet is available as a brand-name drug and a generic drug. (healthline.com)
20231
  • 2023. https://im.unboundmedicine.com/medicine/view/Davis-Drug-Guide/51452/5/loperamide. (unboundmedicine.com)
Symptoms8
  • The most frequent symptoms of loperamide overdose are drowsiness, vomiting, and abdominal pain, or burning. (wikipedia.org)
  • 1 Recently, perhaps as a result of efforts to reduce access to opiates, loperamide has been abused by opiate addicts to ward off the symptoms of withdrawal. (pharmacytimes.com)
  • The use of loperamide at high doses to avoid symptoms of heroin withdrawal has been steadily increasing since 2003. (jabfm.org)
  • We report a case of loperamide used to alleviate symptoms of heroin withdrawal. (jabfm.org)
  • Symptoms of TD and use of medications, such as loperamide and AMDs, were included in the posttravel questionnaires. (cdc.gov)
  • While there is no cure for IBS, you often can control symptoms through diet, stress management and prescription drugs. (healthywomen.org)
  • People often think all cancer drugs cause nausea and vomiting, but these symptoms are more likely with certain drugs and with certain situations. (merckmanuals.com)
  • Researchers report several new direct acting antiviral, drugs commonly used to treat Hepatitis C, improve symptoms of PTSD. (neurosciencenews.com)
Adverse6
  • A review of loperamide in children under 12 years old found that serious adverse events occurred only in children under three years old. (wikipedia.org)
  • Due to the potential for serious adverse outcomes, it would be prudent to avoid the use of loperamide in patients taking amiodarone or lapatinib, or combinations of drugs that inhibit multiple loperamide elimination pathways. (pharmacytimes.com)
  • In a recent statement, the US Food & Drug Administration (FDA) addressed the association between high dose loperamide and adverse cardiac events including QT interval prolongation, torsades de pointes, ventricular arrhythmias, and cardiac arrest. (jabfm.org)
  • Many drugs can alter a person's thinking and judgment, and can lead to health risks, including addiction, drugged driving, infectious disease, and adverse effects on pregnancy. (nih.gov)
  • Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. (ehealthme.com)
  • No drug-related adverse event was reported throughout the study. (walshmedicalmedia.com)
Dose8
  • If you are taking loperamide liquid, do not use a household spoon to measure your dose. (nih.gov)
  • Median loperamide milk concentrations were 0.18 mcg/L at 12 hours after the first dose, 0.27 mcg/L at 6 hours after the second dose, and 0.19 mcg/L at 24 hours after the second dose. (nih.gov)
  • A safe dose of loperamide is different for an adult than for a child. (everydayhealth.com)
  • Therefore, when a patient takes a 2-mg dose, only 0.006 mg of loperamide reaches systemic circulation. (pharmacytimes.com)
  • Patients taking loperamide should be counseled to avoid taking more than the labeled dose. (pharmacytimes.com)
  • Doctors may give these drugs before a dose of chemotherapy as well as to treat nausea and vomiting after it has started. (merckmanuals.com)
  • Here we profile almost 3,000 dose-resolved combinations of antibiotics, human-targeted drugs and food additives in six strains from three Gram-negative pathogens- Escherichia coli , Salmonella enterica serovar Typhimurium and Pseudomonas aeruginosa -to identify general principles for antibacterial drug combinations and understand their potential. (nature.com)
  • Initiate loperamide with the first dose of Nerlynx and continue during first 2 cycles (56 days) of treatment. (drugtopics.com)
Overdose1
  • See also Precautions, Drug Interactions , and Overdose sections. (webmd.com)
Dosage3
  • Loperamide has not been studied during breastfeeding, but the loperamide prodrug, loperamide oxide, has been studied in a dosage of 2 doses of 4 mg given 12 hours apart to 6 women 18 to 47 hours after delivery. (nih.gov)
  • Your doctor may lower your dosage of this drug if you need to take it with gemfibrozil. (healthline.com)
  • Your doctor may decrease your dosage of these drugs if you need to take them with gemfibrozil. (healthline.com)
Constipation3
Efflux2
  • CNS exposure to loperamide is further limited by P-glycoprotein (P-gp) efflux at the blood-brain barrier. (pharmacytimes.com)
  • 5 Inhibitors of P-gp also increase the plasma concentration of loperamide (2- to 3-fold) and may increase the loperamide CNS concentration by reducing the effectiveness of the blood-brain barrier (P-gp mediated) efflux. (pharmacytimes.com)
Stools3
  • You should not use this remedy in case you are oversensitive to loperamide, or if you have stools that are silly, dim, or waver, or in case you have detached insides that is brought on by taking an against microbial. (medicinesmexico.com.mx)
  • Before taking loperamide, tell your master in case you have a fever, natural liquid in your stools, a history of liver disease, or if you are taking a hostile to contamination. (medicinesmexico.com.mx)
  • Loperamide is a treatment for diarrhoea and works quickly to settle loose stools. (drfelix.co.uk)
Medications8
  • Your doctor will probably tell you not to take loperamide if you are taking any of these medications or if you have any of these conditions. (nih.gov)
  • Loperamide is in a class of medications called antidiarrheal agents. (nih.gov)
  • tell your doctor and pharmacist if you are allergic to loperamide, any other medications, or any of the ingredients in loperamide products. (nih.gov)
  • If the condition fails to respond to simple antidiarrheal drugs, anti-inflammatory or immunosuppressive medications may be required. (medscape.com)
  • We found no studies that assessed possible risks posed by non-AMD antidiarrheal medications for treating TD, such as loperamide. (cdc.gov)
  • Taking loperamide with certain other medications may also cause harm. (webmd.com)
  • A class of drugs is a group of medications that work in a similar way. (healthline.com)
  • Empaveli contains the active drug pegcetacoplan, which belongs to a class of medications called complement inhibitors. (medicalnewstoday.com)
Prescription15
  • Prescription loperamide is also used to reduce the amount of fluid in people with ileostomies (surgery to create an opening for waste to leave the body through the abdomen). (nih.gov)
  • Prescription loperamide is sometimes taken on a schedule (one or more times a day). (nih.gov)
  • taking a prescription drug. (nih.gov)
  • Loperamide may interact with certain prescription drugs. (nih.gov)
  • Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. (drugs.com)
  • Gemfibrozil is a prescription drug. (healthline.com)
  • This is another reminder that all drugs, including those sold without a prescription, can be dangerous when not used as directed. (cbsnews.com)
  • Still, officials from the Drug Enforcement Administration say that more people report using controlled prescription drugs than cocaine, heroin and methamphetamine combined. (upstate.edu)
  • For more information, see the Misuse of Prescription Drugs Research Report . (nih.gov)
  • The pattern of drug supply from pharmacies, whether by prescription, recommendation from the pharmacist or a request for a particular product by the client, was assessed. (who.int)
  • Information was collected on all drugs dispensed from the pharmacy (with and without a prescription) during a six-hour study period. (who.int)
  • The objective of this critical review was to determine how social media big data can be used to understand communication and behavioral patterns of problematic use of prescription drugs. (jmir.org)
  • Based on a critical review process, we propose a typology with key initiatives to address the knowledge gap in the use of social media for research on prescription drug abuse and addiction. (jmir.org)
  • Studies that met our inclusion criteria (eg, use of social media data concerning non-medical use of prescription drugs, data informatics-driven findings) were reviewed for knowledge synthesis. (jmir.org)
  • We developed a typology to better understand non-medical, problematic use of prescription drugs through the lens of social media big data. (jmir.org)
Concentrations2
  • This has prompted warnings from the FDA regarding the safety of loperamide, particularly at high plasma concentrations. (pharmacytimes.com)
  • 3,4 At supratherapeutic plasma concentrations, loperamide prolongs the QRS complex and slows repolarization of the ventricle. (pharmacytimes.com)
Antimicrobial3
  • AMD, antimicrobial drugs. (cdc.gov)
  • Resistance to antimicrobial drugs (AMDs) is predisposed in areas with poor hygiene and weak or nonexistent antimicrobial policy. (cdc.gov)
  • Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy. (nature.com)
Interactions4
  • Examples of drugs that can cause interactions with gemfibrozil are listed below. (healthline.com)
  • Despite the phylogenetic relatedness of the three species, more than 70% of the drug-drug interactions that we detected are species-specific and 20% display strain specificity, revealing a large potential for narrow-spectrum therapies. (nature.com)
  • 9. Breast cancer resistance protein (ABCG2) in clinical pharmacokinetics and drug interactions: practical recommendations for clinical victim and perpetrator drug-drug interaction study design. (nih.gov)
  • 16. Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions. (nih.gov)
Interaction7
  • Drug interaction data on loperamide are rather limited. (pharmacytimes.com)
  • An interaction is when a substance changes the way a drug works. (healthline.com)
  • Assessment of a candidate marker constituent predictive of a dietary substance-drug interaction: case study with grapefruit juice and CYP3A4 drug substrates. (nih.gov)
  • Regulatory guidances for dietary substance-drug interaction assessment are lacking. (nih.gov)
  • First, the GFJ-loperamide interaction was assessed in 16 healthy volunteers. (nih.gov)
  • Fig. 1: Principles of drug-drug interaction networks. (nature.com)
  • Fig. 2: Drug-drug interaction conservation. (nature.com)
Capsule1
  • The objective of this study was to compare the rate and extent of drug absorption of the test product (Colodium 2 mg Capsule, Hovid Bhd. (walshmedicalmedia.com)
Strengths2
Slows1
  • Loperamide slows down food travelling through your intestines to give you time to reabsorb water. (drfelix.co.uk)
Microscopic colitis1
  • 18] Anecdotal reports of a large number of additional drugs have been associated with the onset of microscopic colitis. (medscape.com)
Rats1
  • In the distribution studies in rats, loperamide has been shown to be a P-glycoprotein substrate which has a high affinity for the receptors of the longitudinal muscle layer at the gut wall. (walshmedicalmedia.com)
Allergic reaction2
  • A very serious allergic reaction to this drug is rare. (webmd.com)
  • An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. (patientassistance.com)
Travelers1
  • Loperamide, a drug with both antisecretory and antimotility effects ( 11 ), is widely used by travelers ( 12 ). (cdc.gov)
CYP3A42
  • As is true of many drugs with very low bioavailability, loperamide is metabolized primarily by CYP3A4, with some contribution from CYP2C8. (pharmacytimes.com)
  • CYP3A4 and CYP2C8 inhibitors have been reported to increase the plasma concentration of loperamide by about 2- and 4-fold, respectively, and by over 12-fold when both enzymes are inhibited concurrently. (pharmacytimes.com)
Antibiotic3
  • Finally, we demonstrate that several synergies are effective against multi-drug-resistant clinical isolates in vitro and during infections of the larvae of the greater wax moth Galleria mellonella , with one reverting resistance to the last-resort antibiotic colistin. (nature.com)
  • Brown, D. Antibiotic resistance breakers: can repurposed drugs fill the antibiotic discovery void? (nature.com)
  • Lopamide 2 mg has an antibiotic medicine, Loperamide which basically works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. (cheapmedicineshop.com)
Opioids1
  • The transcellular movement of the various opioids, including loperamide and morphine, was assessed in L-MDR1 (expressing P-glycoprotein) and LLC-PK1 cell monolayers (P-glycoprotein expression absent). (nih.gov)
Diphenoxylate1
Abuse3
  • In a statement, lead study author William Eggleston, Pharm.D., of the Upstate New York Poison Center, in Syracuse, New York, said that although loperamide is very safe when used properly, doctors need to be more aware of its abuse. (cbsnews.com)
  • Health care providers must be aware of increasing loperamide abuse and its under recognized cardiac toxicity. (cbsnews.com)
  • We elaborate on theoretical applications, ethical challenges and methodological considerations when using social media big data for research on drug abuse and addiction. (jmir.org)
Nausea1
  • Frequently, drugs to treat nausea are prescribed before and after this drug is given. (patientassistance.com)
Inflammatory2
  • In the colon, the diazo bond is cleaved by the bacterial flora and the active 5-ASA is released to function as a topical anti-inflammatory drug. (medscape.com)
  • Patients who fail to respond adequately to topical anti-inflammatory drugs may benefit from a course of corticosteroid therapy. (medscape.com)
Arrhythmias1
  • At these doses, the plasma loperamide concentration can exceed 100 ng/mL. 2 In addition to decreasing gut motility, these large doses can cause sedation, urinary retention, respiratory depression, cardiac arrhythmias, and death. (pharmacytimes.com)
Pharmacist1
  • To find out how this drug might interact with something else you're taking, talk to your doctor or pharmacist. (healthline.com)
Breast milk3
  • Secretion of the antidiarrhoeal agent loperamide oxide in breast milk. (nih.gov)
  • Loperamide can be present in breast milk, and is not recommended for breast-feeding mothers. (wikipedia.org)
  • It is not known whether this drug is excreted into breast milk. (patientassistance.com)
Antidiarrhoeal1
  • Antidiarrhoeal drugs will slightly shorten how long you have diarrhoea for and may help you get back on your feet, but they should only be taken out of absolute necessity. (hda-online.org.uk)
20211
  • In 2021 , the Food and Drug Administration (FDA) approved Empaveli to treat PNH. (medicalnewstoday.com)
Pharmacists2
  • When counseling patients about the appropriate use of loperamide, pharmacists should ask patients about other drugs they are taking. (pharmacytimes.com)
  • This information is important to the Faculty of Pharmacy at the University of Alexandria, where there is interest in addressing the role of pharmacists in the community to ensure relevant drug use and health care. (who.int)
20161
Liquid2
Stomach2
  • Loperamide is also used to reduce the amount of stool in people who have an ileostomy (re-routing of the bowel through a surgical opening in the stomach). (everydayhealth.com)
  • Loperamide is in like manner used to diminishing the measure of stool in people who have an ileostomy (re-guiding of the entrail through a surgical opening in the stomach). (medicinesmexico.com.mx)
Capsules2
Substrate1
  • Loperamide was a substrate showing high dependence on P-glycoprotein in that basal-apical transport was nearly 10-fold greater than in the apical-basal direction in L-MDRI cells. (nih.gov)
Supplements1
  • Loperamide moderates the beat of preparing so that the little inner parts have all the more an opportunity to acclimatize fluid and supplements from the foods you devour. (medicinesmexico.com.mx)
Ingredients1
  • Please note: different generic brands of loperamide may contain different inactive ingredients than those stated here. (drfelix.co.uk)
Interact1
Pathways1
  • The research, described in Proceedings of the National Academy of Sciences , shows that the drug acts on cellular cholesterol pathways, and suggests that these pathways may be fruitful targets for treating a variety of brain cancers. (sciencedaily.com)
Medicines1
  • Do not take antacids or antidiarrheal medicines (eg, loperamide) within 1 hour before or after taking Urised. (drugs.com)
Side effects8
  • Studies suggest that loperamide is more effective and has lower neural side effects. (wikipedia.org)
  • However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. (healthline.com)
  • You may experience side effects after taking loperamide. (drfelix.co.uk)
  • How can I cope with loperamide side effects? (drfelix.co.uk)
  • The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. (medicalnewstoday.com)
  • People also often lose their hair, but other side effects vary according to the type of drug. (merckmanuals.com)
  • Like most drugs, Lipitor may cause mild or serious side effects. (healthline.com)
  • Mild side effects of many drugs may go away within a few days to a couple of weeks. (healthline.com)
Addiction1
  • Information on commonly used drugs with the potential for misuse or addiction can be found here. (nih.gov)
Misuse1
  • 2 , 3 , 4 Forty-eight documented cases of cardiac problems associated with loperamide misuse were reported to the FDA from 1976 to 2015, 10 of which were fatal. (jabfm.org)