• 2017
  • In the recent times, the global market for Emea europe middle east and africa cephalosporin drugs market report 2017 has surfaced as one of the most promising markets in the pharmaceutical industry, thanks to the significant rise in research and development activities by leading vendors of Emea europe middle east and africa cephalosporin drugs market report 2017 across the world. (qyresearchreports.com)
  • Manufacturers have turned to technological innovations and data-driven customization to satisfy the augmenting consumer demand for efficiency and more accuracy in results, leading to an increased usage of technology in the Emea europe middle east and africa cephalosporin drugs market report 2017 production processes, which is also reflecting positively on the growth of this market. (qyresearchreports.com)
  • The research report on the Emea europe middle east and africa cephalosporin drugs market report 2017 is an analytical study which comprehensively analyzes the competitive framework of this market. (qyresearchreports.com)
  • Using a number of effective assessment tools, such as porter's five forces and value chain analysis, it performs in-depth analyses of the production and supply as well as the demand and sales of Emea europe middle east and africa cephalosporin drugs market report 2017 and provides deep insights into the future prospects of this market. (qyresearchreports.com)
  • The study begins with a detailed overview of the market for Emea europe middle east and africa cephalosporin drugs market report 2017, including the definition, classification, and industry chain structure of Emea europe middle east and africa cephalosporin drugs market report 2017, and move forward to cover every aspect of this market, counting several criteria based on which the market is classified. (qyresearchreports.com)
  • With chemical industry undergoing a phase of technological disruption, innovations in products are likely to shape the future of the Emea europe middle east and africa cephalosporin drugs market report 2017. (qyresearchreports.com)
  • Further, it offers an estimation of the market size in terms of value (US$) and in volume (kilo tons) and talks about the key segments and the geographical subdivisions of the market for Emea europe middle east and africa cephalosporin drugs market report 2017 in details. (qyresearchreports.com)
  • It provides in-depth information on the development trends and the policies and regulations, concerning Emea europe middle east and africa cephalosporin drugs market report 2017, implemented in each of the geographical segments. (qyresearchreports.com)
  • The predominant applications of the Emea europe middle east and africa cephalosporin drugs market report 2017 have also been discussed at length in this research study. (qyresearchreports.com)
  • strains
  • To calculate the market size, the report considers revenue generated from the sales of various prescription drugs along with the generic drugs used for the treatment of various infectious diseases caused by the different strains of bacteria. (emailwire.com)
  • Malaria in 2012 has become a resurgent threat in South East Asia and sub-Saharan Africa, and drug-resistant strains of Plasmodium falciparum are posing massive problems for health authorities. (wikipedia.org)
  • Some Morganella morganii, Proteus vulgaris, Providencia rettgeri, Pseudomonas aeruginosa, and Serratia marcescens strains have also developed resistance to cephalosporins to varying degrees. (wikipedia.org)
  • compounds
  • History of cephalosporins Cephalosporin compounds were first isolated from cultures of Cephalosporium acremonium from a sewer in Sardinia in 1948 by Italian scientist Giuseppe Brotzu He noticed that these cultures produced substances that were effective against Salmonella typhi , the cause of typhoid fever, which had beta-lactamase. (blogspot.in)
  • Natural products sometimes have therapeutic benefit as traditional medicines for treating diseases, yielding knowledge to derive active components as lead compounds for drug discovery. (wikipedia.org)
  • Examples of drug compounds isolated from crude preparations are morphine, the active agent in opium, and digoxin, a heart stimulant originating from Digitalis lanata. (wikipedia.org)
  • efficacy
  • Each subsequent generation of these drugs demonstrates greater efficacy against gram-negative bacteria. (blogspot.in)
  • This study is to assess if the efficacy of cephalosporin is similar to the efficacy of norfloxacin in the acute cystitis treatment. (clinicaltrials.gov)
  • They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs. (wikipedia.org)
  • Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability. (wikipedia.org)
  • 2000
  • In 2000, TAP's withdrew its new drug application for apomorphine (branded as "Uprima") as a treatment for erectile dysfunction after an FDA review panel raised questions about the drug's safety, due to many clinical trial subjects fainting after taking the drug. (wikipedia.org)
  • 1975
  • Under the 1975 CSP, Lilly gave hospitals an additional 3% rebate based on the purchases of specified minimum quantities of any three of Lilly's five cephalosporins. (wikipedia.org)
  • Lilly
  • SmithKline Corp. (SKC) and Eli Lilly and Co. (Lilly) were manufacturers of prescription drugs, including antibiotics. (wikipedia.org)
  • Lilly had patents on all its cephalosporin antibiotics except Kefzol (cefazolin), which this case concerns. (wikipedia.org)
  • Before 1973 Lilly adopted a marketing program known as the Cephalosporin Savings Plan (CSP), designed to make its cephalosporins more competitive with other antibiotics. (wikipedia.org)
  • The CSP provided that a rebate in the form of Lilly merchandise would be paid to hospitals based on the total amount of Lilly cephalosporins that they purchased. (wikipedia.org)
  • Lilly dominated the cephalosporin market with its sales of Keflin and Keflex, but its Kefzol and SKC's Ancef were in direct competition with comparable sales. (wikipedia.org)
  • Hospitals were free to purchase SmithKline's Ancef with their Keflin and Keflex orders with Lilly, so no tie-in was compelled, but if they did so they risked loss of the 3% rebate on all cephalosporin purchases from Lilly, where 75% of the total was Keflex and Keflin. (wikipedia.org)
  • The district court found that Lilly monopolized the cephalosporin market. (wikipedia.org)
  • The district court concluded: Lilly, by linking its most powerful cephalosporin products, Keflin and Keflex, to its unpatented product, Kefzol, has unlawfully used its monopoly power to foreclose competition in and to exclude competition from the cephalosporin market. (wikipedia.org)
  • The court recognized that Lilly began with a lawful patent monopoly on its patented drugs. (wikipedia.org)
  • cefaclor
  • Cefaclor belongs to the family of antibiotics known as the cephalosporins (cefalosporins). (wikipedia.org)
  • Cefaclor CD is a sustained release form of Cefaclor which releases the drug, to the body over a longer period of time, which means that doses can be taken less frequently, with steadier levels of the drug in, the bloodstream. (wikipedia.org)
  • resistance
  • In short, the lack of concerted effort by governments and the pharmaceutical industry, together with the innate capacity of microbes to develop resistance at a rate that outpaces development of new drugs, suggests that existing strategies for developing viable, long-term anti-microbial therapies are ultimately doomed to failure. (wikipedia.org)
  • Without alternative strategies, the acquisition of drug resistance by pathogenic microorganisms looms as possibly one of the most significant public health threats facing humanity in the 21st century. (wikipedia.org)
  • Drug, toxin, or chemical resistance is a consequence of evolution and is a response to pressures imposed on any living organism. (wikipedia.org)
  • Unless the drug used makes sexual reproduction or cell-division or horizontal gene transfer impossible in the entire target population, resistance to the drug will inevitably follow. (wikipedia.org)
  • This can be seen in cancerous tumors where some cells may develop resistance to the drugs used in chemotherapy. (wikipedia.org)
  • Drug resistance develops naturally, but careless practices in drug supply and use are hastening it unnecessarily. (wikipedia.org)
  • Resistance to cephalosporin antibiotics can involve either reduced affinity of existing PBP components or the acquisition of a supplementary β-lactam-insensitive PBP. (wikipedia.org)
  • molecule
  • The idea that the effect of a drug in the human body is mediated by specific interactions of the drug molecule with biological macromolecules, (proteins or nucleic acids in most cases) led scientists to the conclusion that individual chemicals are required for the biological activity of the drug. (wikipedia.org)
  • EMEA
  • In this report, the EMEA Cephalosporin Drugs market is valued at USD XX million in 2016 and is expected to reach USD XX million by the end of 2022, growing at a CAGR of XX% between 2016 and 2022. (qyresearchreports.com)
  • aerobic
  • The aerobic mold which yielded cephalosporin was found in the sea near a sewage outfall in Su Siccu, by Cagliari harbour in Sardinia, by the Italian pharmacologist Giuseppe Brotzu in July 1945. (wikipedia.org)
  • medications
  • The pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications. (wikipedia.org)
  • Phenobarbital was among the most widely used drugs for the treatment of epilepsy through the 1970s, and as of 2014, remains on the World Health Organizations list of essential medications. (wikipedia.org)
  • In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. (wikipedia.org)
  • resistant
  • When an organism is resistant to more than one drug, it is said to be multidrug-resistant. (wikipedia.org)
  • Drug-resistant traits are accordingly inherited by subsequent offspring, resulting in a population that is more drug-resistant. (wikipedia.org)
  • This protein stimulates the growth of cancer cells which are drug-resistant. (wikipedia.org)
  • dose adjustment
  • Warfarin) - change in patient's clinical condition, particularly associated with liver disease, intercurrent illness, or drug administration, necessitates more frequent testing of INR, and dose adjustment as necessary. (wikipedia.org)
  • organisms
  • Individual organisms vary in their sensitivity to the drug used and some with greater fitness may be capable of surviving drug treatment. (wikipedia.org)
  • newer
  • Although disulfiram remained the most common pharmaceutical treatment of alcohol abuse till the end of the 20th century, today it is often replaced or accompanied with newer drugs, primarily the combination of naltrexone and acamprosate, which directly attempt to address physiological processes in the brain associated with alcohol abuse. (wikipedia.org)
  • known
  • However, one of the problems with "natural" medicines, herbal products, and nutritional supplements , etc is that their exact contents often are unknown, And even when known, there is little research on interations with other drugs. (healthtap.com)
  • This approach is known as classical pharmacology, forward pharmacology, or phenotypic drug discovery. (wikipedia.org)
  • alcohol
  • Disulfiram (sold under the trade names Antabuse and Antabus) is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). (wikipedia.org)
  • Disulfiram does not reduce alcohol cravings, so a major problem associated with this drug is extremely poor compliance. (wikipedia.org)
  • This is thought to be due to the N-methylthiotetrazole side-chain of these cephalosporins, which blocks the enzyme vitamin K epoxide reductase (likely causing hypothrombinemia) and aldehyde dehydrogenase (causing alcohol intolerance). (wikipedia.org)
  • kidneys
  • Primaxin is cleared from the body by the kidneys, so it is important to tell one's doctor about any other drugs being taken that are also cleared through the kidneys (such as other antibiotics), especially for older patients, as kidney function declines with age. (wikipedia.org)
  • treatment
  • The primary endpoint of this study will be the bacteriological eradication rate obtained 5-9 days following the end of the treatment with study drugs. (clinicaltrials.gov)
  • Anticipate
  • We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels. (nih.gov)
  • Pharmacology
  • This made for the beginning of the modern era in pharmacology, as pure chemicals, instead of crude extracts of medicinal plants, became the standard drugs. (wikipedia.org)
  • sales
  • In 1998 Takeda established its own US R&D and sales force, for the diabetes drug pioglitazone (Actos). (wikipedia.org)
  • By 2008, Takeda's own sales in the US outside of TAP had grown to $3 billion, mostly from sales of pioglitazone which by then was the best-selling diabetes drug in the world. (wikipedia.org)
  • include
  • Methods to improve compliance include subdermal implants, which release the drug continuously over a period of up to 12 weeks, and supervised administration practices, for example, having the drug regularly administered by one's spouse. (wikipedia.org)
  • clinical
  • In large clinical trials, imipenem was associated with transient and asymptomatic elevations in serum aminotransferase levels in about 6% of patients given the drug for five to 14 days. (wikipedia.org)
  • Once a compound that fulfills all of these requirements has been identified, it will begin the process of drug development prior to clinical trials. (wikipedia.org)
  • The drug requires very expensive Phase I, II and III clinical trials, and most of them fail. (wikipedia.org)
  • classes
  • Adamantane and neuraminidase inhibitor classes of drugs that are approved for treating or preventing influenza A are prohibited therapy in chickens, turkeys, and ducks. (avma.org)