• genes
  • Genes often affect particular traits through secondary pleiotropic pathways, as the classical trait of bristle number in Drosophila has shown. (genetics.org)
  • Development
  • During development of the Drosophila wing, three molecules have been proposed to act as morphogens: Wingless (Wg), Hedgehog (Hh) and Decapentaplegic (Dpp), a homolog of vertebrate bone morphogenetic proteins (BMPs). (biologists.org)
  • These characteristics explain why Drosophila models have paved the way for the development of initial fast screening for potential drug candidates in vivo, and represent also a promising tool for biomedical research in neuroscience. (ed.ac.uk)
  • high
  • Interestingly, these Drosophila neurodegenerative disease models show a high degree of conservation in the fundamental biological pathways and in the molecular, genetic and pathophysiological aspects of neurodegenerative human diseases. (ed.ac.uk)