Doses leukemia radiation induced. Medical search. Frequent questions

Chromosome changes of the same type in primary AML occur in most cases os of chemotherapy-induced myelodysplasia and AML. (standardofcare.com)
I developed chemotherapy-induced cardiomyopathy and atrial fibrillation in December of 2010. (peoplebeatingcancer.org)
The use of a treatment protocol consisting of a mucositis solution associated with low-level laser therapy effectively resolved a case of severe chemotherapy-induced oral mucositis. (bvsalud.org)
Chemotherapy-induced mucositis is one of the most important undesirable side effects of cancer treatment, promoting the worst cases of morbidity, increasing length of hospital stay, and frequently reducing the odds of controlling the tumor and the patient's life expectancy 1 . (bvsalud.org)

Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. (wikipedia.org)
Brachytherapy, in which a radioactive source is placed inside or next to the area requiring treatment, is another form of radiation therapy that minimizes exposure to healthy tissue during procedures to treat cancers of the breast, prostate, and other organs. (wikipedia.org)
The use of radiation therapy in non-malignant conditions is limited partly by worries about the risk of radiation-induced cancers. (wikipedia.org)
Different cancers respond to radiation therapy in different ways. (wikipedia.org)
The majority of epithelial cancers are only moderately radiosensitive, and require a significantly higher dose of radiation (60-70 Gy) to achieve a radical cure. (wikipedia.org)
Combining radiation therapy with immunotherapy is an active area of investigation and has shown some promise for melanoma and other cancers. (wikipedia.org)
Risks for other radiation-induced cancers, including leukaemia, are considered to be very much lower than for lung cancer. (reason.com)
No increase of leukemia or other cancers has been established following exposure to uranium or DU. (reason.com)
Scientists knew even before 1945 that radiation can mutate genes and cause cancer, so it came as no surprise that cancers that showed up at higher than usual rates among bomb survivors. (insidescience.org)
Emergency nuclear scenarios suggest asking older retirees to volunteer, not because they're more expendable, or even because they're more skilled, but because even if they're exposed to massive amounts of radiation, history has shown they would die of old age before they die of radiation induced cancers, which can take decades to develop. (workerscompinsider.com)
While radiation-induced cancers are a serious worry for those exposed to high doses of radiation, they usually take at least a few years to set in. (workerscompinsider.com)
This type of transplant is commonly used in the treatment of certain cancers, such as multiple myeloma, lymphoma, and leukemia. (peoplebeatingcancer.org)
Treatment of various cancers increasingly involves cytoreductive therapy, including high dose chemotherapy or radiation therapy. (justia.com)
While its anticarcinogenic properties are still under study, some scientists believe licorice may have preventative benefits against certain cancers, primarily colorectal cancer and leukemia [2,3]. (leanfactor.com)
Showing posts with label radiation-induced cancers . (prostatecancer.news)
While radiation therapy cures many cancers, many men worry that radiation-induced sub-lethal damage to healthy tissue may someday result in a second primary cancer in the irradiated field. (prostatecancer.news)
Studies have to follow patients for a very extended length of time before radiation-induced second cancers are likely to show up. (prostatecancer.news)
An attempt must be made to separate second primary cancers due to other causes from second primary cancers due to radiation. (prostatecancer.news)
found an extra 1.6 radiotherapy-induced second primary cancers (RTSPCs) per 1,000 men (0.16%) receiving external beam radiation therapy for prostate cancer compared to men with prostate cancer who had no surgery or radiation in the period of 1972-2002. (prostatecancer.news)
found that after 10 years of follow-up, there were no extra cancers attributable to external beam radiation or brachytherapy. (prostatecancer.news)
They filtered out secondary cancers appearing sooner than 5 years from diagnosis (2 years for leukemias), and adjusted for age, length of follow-up, co-morbidities, hormone therapy and chemotherapy. (prostatecancer.news)

Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a treatment using ionizing radiation, generally provided as part of cancer therapy to either kill or control the growth of malignant cells. (wikipedia.org)
The subspecialty of oncology concerned with radiotherapy is called radiation oncology. (wikipedia.org)
Therapy related leukemia this is complication of treatment that can develop months to years or even decades after exposure to cytotoxic agents or radiotherapy or both. (standardofcare.com)
At high radiation doses, radiation therapy is one of main tools to we have to cure cancer, and we are constantly looking for ways to make radiotherapy more effective and with less side effects. (columbia.edu)
After harvesting, the patient is given high dose chemotherapy or radiotherapy and the bone marrow function is reconstituted by infusion of the cells harvested earlier. (justia.com)
Moreover, estrogens also ameliorated hematopoietic suppression induced by caner radiotherapy or chemotherapy in the clinic [7,8]. (biomedgrid.com)
Radiotherapy-induced second primary cancer (RTSPC) risk is low and may differ by radiation technique. (prostatecancer.news)

Some types of cancer are notably radioresistant, that is, much higher doses are required to produce a radical cure than may be safe in clinical practice. (wikipedia.org)
Lead poisoning and cyclosporine, usually in the higher doses given to transplant patients, alter renal tubular function leading to urate retention. (msdmanuals.com)
children require higher doses. (medscape.com)

Pediatric radiation therapy survivors incur risk for radiation-induced hematological malignancies related to red bone marrow (RBM) dose. (appliedradiationoncology.com)
Excess-radiation-induced hematological malignancies (eg, acute myeloid leukemia) have been observed in survivors of pediatric radiation therapy. (appliedradiationoncology.com)
In the pediatric population, physiologic conversion with age of RBM into yellow bone marrow (YBM) throughout the skeleton and along individual bones alters the RBM distribution and, consequently, the amount of RBM exposed to radiation. (appliedradiationoncology.com)
Moreover, oral mucositis induces pediatric patients to reduce food intake, which affects their nutritional status and makes them less responsive to treatment 4-5 . (bvsalud.org)

Increased production of urate may be caused by increased nucleoprotein turnover in hematologic conditions (eg, lymphoma, leukemia, hemolytic anemia) and in conditions with increased rates of cellular proliferation and cell death (eg, psoriasis, cytotoxic cancer therapy, radiation therapy). (msdmanuals.com)

Therapy related leukemia is most commonly acute myeloid leukemia. (standardofcare.com)
February 11, 2021 - Apamistamab conditioning treatment with targeted radioimmunotherapy to the bone marrow resulted in high rates of successful allogeneic hematopoietic stem cell transplants in patients with active, relapsed, or refractory acute myeloid leukemia. (onclive.com)
Apamistamab (Iomab-B) conditioning treatment with targeted radioimmunotherapy to the bone marrow resulted in high rates of successful allogeneic hematopoietic stem cell transplants in patients with active, relapsed, or refractory acute myeloid leukemia (AML), according to interim results from the phase 3 SIERRA trial, which were presented virtually at the 2021 Transplant and Cellular Therapies Meetings. (onclive.com)
The Working Group was not aware of any good rodent models that simulate the occurrence of acute myeloid leukemia in humans. (who.int)
Therefore, on the basis of the data available at this time, it was not possible to identify a mechanism for the induction of myeloid leukemia in humans. (who.int)
The NCI group has published a recent update of one of their studies, with an additional 10 years of follow-up, and it continues to suggest a possible link between formaldehyde exposure and mortality due to lymphohematopoietic malignancies, particularly myeloid leukemia (Beane Freeman, Blair et al. (who.int)
In CHIP, these mutations are often found in genes associated with myeloid malignancies, such as leukemia. (peoplebeatingcancer.org)

1993. Protective effects of chlorogenic acid, curcumin and beta-carotene against gamma-radiation-induced in vivo chromosomal damage. (cdc.gov)
The aim of this study was to measure the in vivo biodistribution and dosimetry of \(^{177}\)Lu-OPS201 in five anesthetized Danish Landrace pigs as an appropriate substitute for humans to quantitatively assess the absorbed doses for future clinical applications. (uni-wuerzburg.de)
In vivo distributions and absorbed doses of pigs are comparable to those observed in other publications. (uni-wuerzburg.de)

It is important to distinguish the radiosensitivity of a particular tumor, which to some extent is a laboratory measure, from the radiation "curability" of a cancer in actual clinical practice. (wikipedia.org)
Recent clinical research from Massachusetts General Hospital has shown that radiation during CT scans can be dramatically lowered software from SharpView. (dotmed.com)
This finding suggests that further study is warranted with a larger sample set that is more uniformly distributed in age and sex to assess the impact on clinical or research studies of the risk of subsequent hematological malignancies for survivors of childhood radiation therapy. (appliedradiationoncology.com)
The clinical diagnosis of infiltrative ocular leukemia (e.g. typical findings and a history of systemic leukemia) is typically adequate for treatment of patients. (eyecancer.com)
Objective To assess the risk of meningioma associated with use of high dose cyproterone acetate, a progestogen indicated for clinical hyperandrogenism. (bmj.com)

Since radiation is a well-known inducer of both leukemia and chromosomal translocations, it has long been suspected that radiation might cause leukemia by inducing specific translocations. (bioone.org)

1-5 The risks of developing these malignancies are related to the absorbed dose deposited in the active red bone marrow (RBM). (appliedradiationoncology.com)
However, they noted that such damage from low-dose radiation in other radiology workers has been associated with malignancies in previous research. (auntminnie.com)

Are There Safe Levels of Radiation? (infiniteunknown.net)
U.S. authorities and the news media have been quick to try to stem any public panic about the levels of radiation exposure here in the U.S. This is more than just spin - while many aren't aware of it, there is a national network of radiation monitors called Radnet . (workerscompinsider.com)
The Power company reports that at least 25 workers and 5 members of Japan's Self Defense Force had were exposed to unsafe levels of radiation. (workerscompinsider.com)
Exposure to high levels of radiation can have severe consequences on human health. (chriswicknews.com)
Long-term exposure to low levels of radiation can also lead to increased risks of cancer, especially when the exposure is prolonged or repeated. (chriswicknews.com)
In order to reduce the overall volume of the radioactive waste, the government has decided to burn radioactive wood, rice straw and grass that contain levels of radiation between 8000 Bq/kg to 100,000 Bq/kg. (311kikin.org)

These include leukemias, most lymphomas, and germ cell tumors. (wikipedia.org)

Furthermore, the UV-radiation sensitivity phenotype of lsm1 Δ is partially rescued by mutations in genes involved in 3′ to 5′ mRNA degradation, and mutations predicted to function in RNA interactions confer the most UV-radiation sensitivity. (bioone.org)
Radiation harm includes not only cancer and leukemia, but reduced immunity and also reduced fertility, increases in other diseases including heart disease, birth defects including heart defects, other mutations. (wiseinternational.org)
Radiation damages the DNA within the cells and can induce mutations that may contribute to the development of various types of cancer, such as leukemia, thyroid cancer, and breast cancer. (chriswicknews.com)

None of the absorbed doses calculated will exceed organ toxicity levels. (uni-wuerzburg.de)

6,7 The associated projected lifetime risks of children who receive radiation therapy may be roughly estimated based on dose-effect models and the RBM dose. (appliedradiationoncology.com)
We work on all of these, trying to understand the radiation risks, so we can maximize the benefits versus the risk in each case. (columbia.edu)
Also there lire many more publications and journals that devote large sections to studies involving possible health risks associated with radiation. (seintl.com)
Understanding the risks associated with radiation exposure is crucial to take appropriate measures for protection. (chriswicknews.com)
To mitigate the risks associated with radiation exposure, various protective measures can be implemented. (chriswicknews.com)
Understanding the sources of radiation and their potential risks is essential for taking appropriate protective measures. (chriswicknews.com)
The mechanism of radiation-induced DNA damage in relation to carcinogenesis is also fairly well understood, and large epidemiological studies have shown significant risks even at low doses. (311kikin.org)

Several chemotherapy agents that include alkylating agents, topoisomerase inhibitors, and tax anew are associated with the development of acute myelogenous leukemia and myelodysplastic syndrome. (standardofcare.com)
The risk of developing secondary acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS) is increased following treatment with doxorubicin hydrochloride. (medscape.com)

Therapy related leukemia accounts for 10-20% of acute myelogenous leukemia cases. (standardofcare.com)
Alkylating agents and topoisomerase II inhibitors induce therapy related leukemia. (standardofcare.com)

Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body, and have not spread to other parts. (wikipedia.org)
Most common cancer types can be treated with radiation therapy in some way. (wikipedia.org)
It is estimated that half of the US' 1.2M invasive cancer cases diagnosed in 2022 received radiation therapy in their treatment program. (wikipedia.org)
The response of a cancer to radiation is described by its radiosensitivity. (wikipedia.org)
Highly radiosensitive cancer cells are rapidly killed by modest doses of radiation. (wikipedia.org)
Renal cell cancer and melanoma are generally considered to be radioresistant but radiation therapy is still a palliative option for many patients with metastatic melanoma. (wikipedia.org)
The Green Party claims that they are "the likely cause of numerous health problems in thousands of Gulf War veterans and their families, including cancer, leukemia, tumors, and high rates of birth defects because of genetic damage. (reason.com)
A Department of Defense-sponsored review of the scientific literature by the RAND think tank concluded that "there are no peer reviewed published reports of detectable increases of cancer or other negative health effects from radiation exposure to inhaled or ingested natural uranium at levels far exceeding those likely in the Gulf. (reason.com)
The International Journal on Cancer, published in its January 2012 magazine a new study from France, establishing a very clear correlation between the frequency of acute childhood leukemia and proximity to nuclear power stations. (wiseinternational.org)
This is in line with a USA study by the National Academy Press, U.S., which argues that women and children are at significantly greater risk of suffering and dying from radiation-induced cancer than a man exposed to the same dose of ionizing radiation. (wiseinternational.org)
This is a very early stage breast cancer that is considered to be a secondary cancer from the radiation for the Hodgkin's. (cancer.org)
This is a secondary cancer from the radiation for the Hodgkin's. (cancer.org)
What we should know is that a millionth of a gram of plutonium, or less, can induce cancer, or will induce cancer. (infiniteunknown.net)
strontium-90 goes to bone, causing bone cancer and leukemia. (infiniteunknown.net)
Another friend that lives in LA, Louie, who frequently drives down to visit me, is currently undergoing radiation and chemotherapy treatment for his cancer. (eastcountymagazine.org)
It's a large population exposed at a wide range of ages, male and female, and at a wide range of doses," said Kiyohiko Mabuchi, an epidemiologist at the National Cancer Institute in Rockville, Maryland. (insidescience.org)
Nested case-control study of occupational chemical exposures and prostate cancer in aerospace and radiation workers. (cdc.gov)
We've worked a lot on improving the radiation treatments for cervical cancer and for prostate cancer, and right now we are really excited about the use of charged particle radiation therapy in the fight against pancreatic cancer. (columbia.edu)
However, individuals with CHIP do not necessarily develop leukemia or any other blood cancer. (peoplebeatingcancer.org)
Six Critiques of "Radiation from Medical Procedures in the Causation of Cancer and Ischemic Heart Disease (IHD)" by John W. Gofman, M.D., Ph.D., Professor Emeritus of Molecular & Cell Biology, Univ. (ratical.org)
Part 8 -- Doctors and Sick People Stay Together * Part 9 -- People Live Long Enough to Die of Cancer * Part 10 -- "Ecologic" Studies Are Inherently Weak * Part 11 -- Natural Radiation Exceeds X-Rays in Dose * Part 12 -- Conclusion: Biologically Consistent Picture * Note 1 and References ------------------------------------------------------------------ Part 1 * What Are the Conclusions Under Review? (ratical.org)
Radiation from Medical Procedures in the Pathogenesis of Cancer and Ischemic Heart Disease" (Gofman 1999) is a massive dose-response study which began extensive circulation for peer-review among scientists in epidemiology, cancer etiology, IHD etiology, and health physics, immediately after its publication in November 1999. (ratical.org)
The study's two principal conclusions are 1) Medical radiation, introduced into medicine in 1896, became and remains a necessary causal co-actor in over half of the fatal cases of cancer in the USA, and 2) became and remains a necessary causal co-actor also in over half of the fatal cases of ischemic heart disease (coronary artery disease) in the USA. (ratical.org)
From these conclusions plus the fact that x-ray harm is approximately proportional to accumulated x-ray dose, it follows that a very great deal of future cancer and ischemic heart disease (IHD) could be prevented by reducing the dose-levels customarily administered during x-ray imaging procedures, especially CT and fluoroscopy. (ratical.org)
The starting point is that ionizing radiations, including x-rays, have been an established cause of human cancer for decades (affirmation in IARC 2000). (ratical.org)
As a result of doing our earlier study of radiation-induced breast cancer (Gofman 1996), we learned that there is no way for anyone to make a reliable estimate of what the average per capita accumulated dose in the USA was --- or is today --- from pre-cancer medical x-rays. (ratical.org)
It also printed material for distribution at schools, which included statements such as "at doses under 100 millisieverts, the risk of cancer from exposure is so small that it will be hidden by the effects of cancer caused by other factors in the natural environment," and "the risk posed by exposure at 100 millisieverts is no greater than not eating vegetables. (311kikin.org)
Late in 1995, the World Health Organisation linked nearly 700 cases of thyroid cancer among children and adolescents to the Chernobyl accident and among these some 10 deaths are attributed to radiation. (mongabay.com)
A male 13-year-old patient with chondroblastic osteosarcoma in the left distal thigh and acute lymphoblastic leukemia undergoing cancer treatment with methotrexate presented with severe oral mucositis. (bvsalud.org)

Nuclear accidents, like the Chernobyl and Fukushima disasters, have demonstrated the long-lasting effects of radiation on ecosystems. (chriswicknews.com)
Nearly 20 years ago Reactor number 4 at Chernobyl exploded, sending radiation across a large region of what is now the Ukraine, Belarus, and Russia. (mongabay.com)
Studying 228 birds of 23 different species captured in Chernobyl, Gaschak and colleagues from the University of South Carolina (US) and University Pierre et Marie Curie (France) measured the birds' levels of radioactive strontium and radioactive cesium, comparing migrating populations with those that remain in the area, as well as examining age, sex, and nesting preferences to determine the amounts and types of radiation accumulating in the birds. (mongabay.com)
Timothy Mousseau will present "Consequences of radiation for reproduction and survival of barn swallows Hirundo rustica from Chernobyl. (mongabay.com)

This study again confirms an earlier German study (KiKK-Study Dec 2007) that the incidence of child leukemia more than doubles near nuclear power plants for children below the age 5 living within a 5 kilometer radius of nuclear power plants, compared to children living further then 20 kilometers from a nuclear power plant. (wiseinternational.org)

The risk of secondary leukemia is associated with the type of cytotoxic agents, cumulative dose, intensity of such agents and cumulative ionizing radiation doses. (standardofcare.com)

Induced leukemia-differences in the ages of patients and differences in the accumulative doses of alkylating agents explain the wide variations in risk from study to study. (standardofcare.com)
Investigators sought to prove with this study that targeted radiation to the marrow with apamistamab, a radioactive iodine ( 131 I)-labeled anti-CD45 antibody, could enable the successful engraftment of patients despite active disease in the marrow. (onclive.com)
Patients in the investigational arm received a dosimetric dose of apamistamab (≤ 20 mCi) approximately 19 days prior to HCT followed by a therapeutic dose of apamistamab, which is individually calculated for each patient based on an upper limit of 24 Gy to the liver. (onclive.com)
After, patients remain on radiation isolation for several days before receiving fludarabine conditioning therapy (30 mg/m 2 /day for 3 days) and finally low-dose total body irradiation (200 cGy) prior to HCT. (onclive.com)
9,10 Accurate estimation of the percentage RBM (%RBM) irradiated depends on how well the patients' actual RBM is delineated, such as by using manual or semi-automatic tissue contouring derived from computed tomography (CT) images and then extracting the mean absorbed dose in those volumes. (appliedradiationoncology.com)
It is reasonable for all patients with leukemia to have periodic eye examinations. (eyecancer.com)
patients will be treated with low-dose external beam radiation therapy. (eyecancer.com)
Individuals in the acupuncture group also reported significant improvement in xerostomia, a condition in which patients receiving adjuvant radiation therapy experience extreme dry mouth. (medicalnewstoday.com)
1. The hazard ratio of skeletal-related events in patients treated with radiation compared with patients who were not treated with radiation was 0.09. (qxmd.com)
There has never been a study, nor is there likely to ever be one, where patients are randomized to receive radiation or receive no radiation and are watched for 10+ years. (prostatecancer.news)
they found a higher rate - 3.7 RTSPCs per 1,000 - in patients receiving salvage radiation for a recurrence after primary prostatectomy. (prostatecancer.news)

Ionizing radiation works by damaging the DNA of cancerous tissue leading to cellular death. (wikipedia.org)

Therefore, they must have been continually exposed to alpha and beta particles as well as to the intense penetrating gamma radiation emitted by radium and its daughter products, including radon. (cdc.gov)
In passing through matter, gamma radiation ionizes via three main processes: the photoelectric effect , Compton scattering , and pair production . (wikidoc.org)

However, on p.276 of IARC Monograph 88 with regard to the ability of formaldehyde to cause leukemia it states: "In summary, there is strong but not sufficient evidence for a causal association between leukemia and occupational exposure to formaldehyde. (who.int)

Our results show that lsm1 Δ increases the UV-radiation sensitivity of the rad1 Δ and rad51 Δ mutants, but not the rad18 Δ mutant, placing LSM1 within the post-replication repair/damage tolerance pathway (PRR). (bioone.org)
Together, these results suggest that Lsm1p may confer protection against UV-radiation damage by protecting the 3′ ends of mRNAs from exosome-dependent 3′ to 5′ degradation as part of a novel RAD5- mediated, PCNA-K164 ubiquitylation-independent subpathway of PRR. (bioone.org)
This radiation deeply penetrates brain, ear and eye tissues, which are especially susceptible to microwave damage. (rense.com)
Cell damage and tumors can be easily induced in the lab at about one third of the FCC's exposure guidelines. (rense.com)
Scientists fear that cell phone radiation could damage human embryos. (rense.com)
Since radiation-induced DNA damage is generated essentially randomly in the genome, it does not seem likely that radiation could ever be responsible for the induction of identical translocations of relevance to ALL in multiple cells of an individual and hence be the primary cause of radiation-related leukemia. (bioone.org)
Several possible mechanisms were considered for the induction of human leukemia, such as clastogenic damage to circulatory stem cells. (who.int)
And today at the Fukushima Nuclear Plant, although a large scale meltdown looks to have been narrowly averted , the extent of the radiation leaks and the related damage are still yet to be fully assessed. (workerscompinsider.com)
Long-term exposure to low-dose radiation can cause DNA damage to lymphocyte cells in interventional radiologists - yet importantly, the doctors are likely not vulnerable to an increased risk of leukemia, according to researchers in Slovakia. (auntminnie.com)
Hematopoietic cells and peripheral blood cells are known to be sensitive to radiation, and low doses of radiation can cause damage. (biomedgrid.com)
In recent years, natural substances such as SH groups and cysteine have been investigated for their effectiveness in protecting from radiation damage [2]. (biomedgrid.com)

Radiation therapy is commonly applied to the cancerous tumor because of its ability to control cell growth. (wikipedia.org)
To spare normal tissues (such as skin or organs which radiation must pass through to treat the tumor), shaped radiation beams are aimed from several angles of exposure to intersect at the tumor, providing a much larger absorbed dose there than in the surrounding healthy tissue. (wikipedia.org)
Besides the tumour itself, the radiation fields may also include the draining lymph nodes if they are clinically or radiologically involved with the tumor, or if there is thought to be a risk of subclinical malignant spread. (wikipedia.org)

Among the remainder, one study found appreciable evidence that exposure to low-dose radiation was associated with circulatory diseases, but five others, all with appreciable power, did not. (bioone.org)
We conclude that long-term exposure to low doses of [ionizing radiation] can induce formation of micronuclei in the PBL of interventional radiologists," the group wrote. (auntminnie.com)

If you inhale a millionth of a gram of plutonium, the surrounding cells receive a very, very high dose. (infiniteunknown.net)
Then there was the radiation: intense bursts of high-energy gamma rays that swept outward spherically from the exploding bombs ahead of the physical force. (insidescience.org)
and that is acknowledging radiation as a known carcinogen and killer at high dose levels. (seintl.com)
For the last one-hundred years many studies have reported the deleterious effects of high-dose radiation exposure. (seintl.com)
Use of high dose. (bmj.com)
Participants had at least one reimbursement for high dose cyproterone acetate and no history of meningioma or benign brain tumour, or long term disease status. (bmj.com)
An ASCT is high dose, aggressive chemotherapy. (peoplebeatingcancer.org)
Hematopoietic cell transplant aka the procedure referred to as a stem cell transplant, either allogeneic or autologous, is high-dose therapy, is aggressive and therefore hard on the myeloma patient's heart. (peoplebeatingcancer.org)
Autologous stem cell transplant (ASCT) refers to a medical procedure in which a person's own stem cells are collected and then reintroduced into their body after high-dose chemotherapy or radiation therapy. (peoplebeatingcancer.org)
Acute radiation syndrome, also known as radiation sickness, can occur within hours or days of exposure to high doses of radiation. (chriswicknews.com)
Some children in the contaminated areas were exposed to high thyroid doses up to 50 gray (Gy) because of an intake of radioactive iodine, a relatively short-lived isotope, from contaminated local milk. (mongabay.com)

Physics Councilor, Radiation Research Society Executive Council, 1993-1996. (columbia.edu)

Radiation therapy may provide palliative relief from symptomatic metastases, control recurrent tumors, and prevent recurrence of advanced resected tumors. (medscape.com)

In the SIERRA trial, patient-specific dosimetry was used to generate an individualized therapeutic dose to target marrow and spare non-hematopoietic organs. (onclive.com)
This is defined by their ability to repopulate an individual whose hematopoietic system has been destroyed by radiation or chemotherapy. (justia.com)

Participants were considered to be exposed when they had received a cumulative dose of at least 3 g during the first six months (139 222 participants) and very slightly exposed (control group) when they had received a cumulative dose of less than 3 g (114 555 participants). (bmj.com)
The adjusted hazard ratio for a cumulative dose of cyproterone acetate of more than 60 g was 21.7 (10.8 to 43.5). (bmj.com)
In a complementary analysis, 463 women with meningioma were observed among 123 997 already using cyproterone acetate in 2006 (risk of 383 per 100 000 person years in the group with the highest exposure in terms of cumulative dose). (bmj.com)

Radiation oncology is the medical specialty concerned with prescribing radiation, and is distinct from radiology, the use of radiation in medical imaging and diagnosis. (wikipedia.org)

A genome-wide screen in Saccharomyces cerevisiae identified LSM1 as a new gene affecting sensitivity to ultraviolet (UV) radiation. (bioone.org)

Two successive ambassadors developed leukemia. (rense.com)

Induced leukemia-the risk is dose dependent and increases exponentially with age after the age of 40 years. (standardofcare.com)
When combined with other deletions affecting PRR, lsm1 Δ increases the UV-radiation sensitivity of the rev3 Δ, rad30 Δ and pol30-K164R mutants but not rad5 Δ. (bioone.org)
This is not surprising because salvage radiation increases the volume of healthy tissue exposed to radiation. (prostatecancer.news)

Those near the hypocenters -- the points on Earth above which the bombs exploded -- absorbed some of the highest doses of radiation ever delivered to humans before or since. (insidescience.org)
Many radiation biologists say that lab and animal studies suggest such low doses are unlikely to be harmful and could in some cases even improve health, but regulators worry that such studies cannot be easily applied to humans. (insidescience.org)
Radiation exposure doesn't only affect humans but also has significant impacts on the environment. (chriswicknews.com)
Yet despite radiation levels dangerous to humans, most natural areas in the region have rebounded, and by ecological standards, are functioning normally. (mongabay.com)
For humans after an injection of 5 GBq \(^{177}\)Lu-OPS201, the highest predicted absorbed doses are obtained for the kidneys (13.7 Gy), the osteogenic cells (3.9 Gy), the urinary bladder wall (1.8 Gy), and the liver (1.0 Gy). (uni-wuerzburg.de)
According to the biodistribution data in pigs, presented in this work, the expected radiation exposure in humans will be within the acceptable range. (uni-wuerzburg.de)

Thickening of the iris, ciliary body and anterior uvea induced a secondary "narrow angle" glaucoma. (eyecancer.com)

1998. Food preservation using ionizing radiation. (cdc.gov)
Recent analyses of mortality among atomic bomb survivors have suggested a linear dose-response relationship between ionizing radiation and diseases of the circulatory system for exposures in the range 0-4 Sv. (bioone.org)
Other studies allowing a comparison of the rates of circulatory disease in individuals drawn from the same population but exposed to ionizing radiation at different levels within the range 0-5 Gy or 0-5 Sv were identified through systematic literature searches. (bioone.org)
We conclude that the other epidemiological data do not at present provide clear evidence of a risk of circulatory diseases at doses of ionizing radiation in the range 0-4 Sv, as suggested by the atomic bomb survivors. (bioone.org)
Most of our work is with ionizing radiation - x rays, neutrons, alpha particles, carbon ions, but there are many other different types of radiation. (columbia.edu)
However, they did find a comparatively increased frequency of micronuclei in the radiologists, which are fragments of DNA produced when ionizing radiation breaks DNA strands. (auntminnie.com)
Radioprotectors are given prior to exposure to ionizing radiation to reduce harmful effects, including radiation-induced lethality [1]. (biomedgrid.com)

Active, relapsed, or refractory AML was defined for the sake of the trial as primary induction failure after ≥ 2 cycles of therapy including chemotherapy or ≥ 2 cycles of venetoclax (Venclexta) with a hypomethylating agent or low-dose cytarabine, first early relapse after first CR of less than 6 months, relapse refractory to salvage chemotherapy regimen, or second or subsequent relapse. (onclive.com)

Radiation therapy has several applications in non-malignant conditions, such as the treatment of trigeminal neuralgia, acoustic neuromas, severe thyroid eye disease, pterygium, pigmented villonodular synovitis, and prevention of keloid scar growth, vascular restenosis, and heterotopic ossification. (wikipedia.org)
At the levels created by most probable sources, not enough radiation would be present in a dirty bomb to kill people or cause severe illness. (apnga.org)
A brown 13-year-old boy with chondroblastic osteosarcoma in the left distal thigh and acute lymphoblastic leukemia presented with severe oral mucositis (Oral Assessment Guide / OAG)6, namely, ulcerated skin and mucosa in the upper and lower lips ( Figure 1 ), and complaints of pain and much discomfort, especially when talking and eating. (bvsalud.org)

Gamma rays (denoted as γ ) are a form of electromagnetic radiation or light emission of frequencies produced by sub-atomic particle interactions, such as electron-positron annihilation or radioactive decay . (wikidoc.org)
A portable nuclear gauge uses very small amounts of radioactive material, Cesium 137 and Americium 241, to produce just enough radiation to measure the density of soils and asphalt. (apnga.org)
Radiation emitted by the radioactive material passes through the soil and is either absorbed/stopped by the soil or makes its way to the detector tubes on the other side of the gauge. (apnga.org)
Natural sources include cosmic radiation from space, radon gas emitted from the Earth's crust, and radioactive elements present in soil and rocks. (chriswicknews.com)

However, recent studies clearly indicate that spontaneous translocations specific to acute lymphocytic leukemia (ALL) actually occur much more frequently than do leukemia cases with the same translocations. (bioone.org)

The radiation burned images of people's clothing into their skin, and thousands more died of acute radiation poisoning in the months after the explosions. (insidescience.org)
203 people were hospitalized immediately, of whom 31 died (28 of them died from acute radiation exposure). (mongabay.com)

While radiation therapy is known to help with painful bone metastases, its role in asymptomatic cases is not well-established. (qxmd.com)

Early-stage, localized disease may be treated with radiation therapy or excision in certain cases. (medscape.com)

Current regulation of radiation and nuclear activity ignores the disproportionately greater harm to both women and children. (wiseinternational.org)
In today's world of far more frequent medical scans and air travel, and widespread deployment of nuclear power, people are far more likely to receive low doses of radiation spread out over years or decades, rather than concentrated doses. (insidescience.org)
At low radiation doses, radiation is important in many different circumstances, ranging all the way from medical CT scans, to radiological terrorism, to airport scanners, to the future of nuclear power, and even to space travel. (columbia.edu)
After the nuclear accident, the Japanese government began to provide radiation safety information on the web pages of various ministries and agencies. (311kikin.org)
Chernobyl's ecosystems seem to be recovering just 19 years after the region was badly contaminated with radiation from a nuclear meltdown according to a report backed by the United Nations. (mongabay.com)

Differential expression of cytochrome P450 genes associated with benzene -induced hematotoxicity. (cdc.gov)
The origin of leukemia is often associated with the development of preleukemic fusion genes (PFGs), which trigger leukemogenesis , the process by which healthy white blood cells become cancerous, the researchers explained. (auntminnie.com)

Increased risk for leukemia has consistently been observed in studies of professional workers and in two of three of the most relevant studies of industrial workers. (who.int)
Risk of leukemia at low doses: the NIOSH multi-site leukemia case-control study. (cdc.gov)
Conclusions A strong dose-effect relation was observed between use of cyproterone acetate and risk of intracranial meningiomas. (bmj.com)
Prior research suggested a link between radiation and a lower risk of SRE. (qxmd.com)
The radiation safety information that these publications rely upon is based on the report by the Working Group on Risk Management for Low Dose Exposure that was published by the Cabinet Secretariat in December 2011. (311kikin.org)
In general, current research agrees with the low dose risk model. (311kikin.org)
However, these two studies that looked at more recent treatment data raises the question as to whether the already small risk of RTSPC has diminished still further with improved radiation technology. (prostatecancer.news)

ACIP statements on individual vaccines and disease updates in MMWR should be consulted for more details regarding the epidemiology of the diseases, im munization schedules, vaccine doses, and the safety and efficacy of the vaccines. (cdc.gov)

Alkylating agents or radiation related and topoisomerase II inhibitor related acute myelogenous leukemia are often related to deletions of monosomies of chromosomes 5 and 7 amd a relatively long latency of 4-6 years. (standardofcare.com)
The patient base for radiation therapy has changed over the years. (prostatecancer.news)
Over the years, there have been a wide variety of radiation technologies and doses used. (prostatecancer.news)

Many people with leukemia try additional treatments outside their standard care, hoping to manage symptoms and, in some cases, to improve their treatment outcome. (medicalnewstoday.com)
Zinc may help reduce some symptoms caused by radiation therapy. (mskcc.org)

8 Because treatment-related radiation exposures are usually highly nonuniform throughout the body, it is important to know the accurate distribution of RBM within children's bodies to estimate RBM doses. (appliedradiationoncology.com)

In: Radiation carcinogenesis. (cdc.gov)
Radiation, carcinogenesis and DNA alterations. (cdc.gov)

Dr. Lai notes that even tiny doses of radiofrequency can cumulate over time and lead to harmful effects. (rense.com)

This paper presents data suggesting that contact current due to V(OC) is an exposure that may explain the reported associations of residential magnetic fields with childhood leukemia. (who.int)
The analysis was motivated by recent research suggesting that the physical location of power lines in the backyard, in contrast to the street, may be relevant to a relationship of power lines with childhood leukemia. (who.int)

This effect of Vitamin c may have some therapeutic implications for radiation-induced injuries. (biomedgrid.com)

Italian scientists have recently demonstrated that cell phone radiation makes cancerous cells grow aggressively. (rense.com)
that you understand internal emitters and radiation, and it's not low level to the cells that are exposed. (infiniteunknown.net)
They were left facing an uncertain future: What long-term impacts would they -- and their future children -- endure from the hits radiation had dealt to their cells and the DNA within? (insidescience.org)
It could be deduced that the uncertainly radioprotective action against death is induced by a possible process of enhanced regeneration of the leukocyte stem cells due to not only strengthened radioresistance and increased numbers of remained leukocyte cells, but also enhanced post-irradiation repair or promoted proliferation of the leukocyte stem cells. (biomedgrid.com)
chronic leukemias are composed of more mature cells. (curehunter.com)

I am just discovering the experience of the long term effects of the radiation, so please forgive me if my reply doesn't exactly fit your condition. (cancer.org)
I have found that most doctors that I have dealt with thus far are unfamiliar with the long term effects of the radiation, and there is a serious lack of research on the topic. (cancer.org)
But many who survived the blasts also recovered from the immediate effects of the radiation. (insidescience.org)

Anatomy18

Organisms15

Diseases54

Chemicals and Drugs50

Analytical, Diagnostic and Therapeutic Techniques and Equipment66

Phenomena and Processes48

Disciplines and Occupations5

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture2

Humanities1

Information Science8

Health Care30

Chemotherapy-induced4

Cancers21

Radiotherapy7

Higher doses3

Pediatric4

Lymphoma1

Myeloid7

Vivo3

Clinical5

Chromosomal1

Malignancies2

Levels of Radiation6

Lymphomas1

Mutations3

Toxicity1

Risks7

Myelodysplastic syndrome2

Therapy related leukemia2

Cancer29

Chernobyl4

Incidence1

Cytotoxic1

Patients11

Leading to cellular1

Gamma radiation2

Cause leukemia1

Damage11

Tumor3

Exposure to low2

High11

19961

Palliative1

Hematopoietic2

Cumulative dose3

Oncology1

Genome1

Successive1

Increases3

Humans6

Secondary1

Ionizing7

Cytarabine1

Severe3

Radioactive4

Occur1

Acute radiation2

Bone Metastases1

Treated with radiation therapy1

Nuclear5

Genes2

Risk7

Diseases1

Years3

Symptoms2

Exposures1

Carcinogenesis2

Harmful effects1

Childhood2

Therapeutic1

Cells5

Effects of the radiation3