• A 52-year-old man treated with oral dantrolene for spasticity after spinal cord injury was scheduled to undergo irrigation and drainage of a thigh abscess under general anesthesia. (ekja.org)
  • In this case report, the muscle relaxant action was assessed during administration of the optimized dose of rocuronium under nerve root monitoring in general anesthesia for a patient with long-term dantrolene administration. (ekja.org)
  • There are many kinds of sedation and general anesthesia that a Dentist Anesthesiologist can use to put together a unique, customized formula for each patient. (asda.org)
  • What's the difference between sedation and general anesthesia? (asda.org)
  • While under general anesthesia, patients are completely asleep during the procedure. (asda.org)
  • General anesthesia is typically used in longer, more complex procedures or with patients who may be unable to cooperate. (asda.org)
  • An introduction to perioperative alternatives to opioids for general anesthesia, and a discussion of how reduced opioid use impacts patient care. (asda.org)
  • Ketamine has been utilized in short-term medical procedures that do not require skeletal muscle relaxation, and it has the approval for induction of general anesthesia as a pre-anesthetic to other general anesthetic agents. (empowerpharmacy.com)
  • Conscious sedation has become established as an important alternative to general anesthesia (GA) in dental treatment of patients with intellectual disability (ID). (bvsalud.org)
  • Possible regional anesthesia techniques include epidural analgesia, spinal analgesia (sometimes referred to as the intrathecal or subarachnoid space), or a combination of epidural and spinal analgesia. (medscape.com)
  • Regional anesthesia is contraindicated in the presence of actual or anticipated serious maternal hemorrhage , refractory maternal hypotension, coagulopathy, untreated bacteremia , raised intracranial pressure, skin or soft tissue infection at the site of the epidural or spinal placement, and anticoagulant therapy. (medscape.com)
  • As exacerbation of neurological diseases might be attributed without cause to the anesthetic agent, many clinicians avoid regional anesthesia in its presence. (medscape.com)
  • 02. Albright GA - Cardiac arrest following regional anesthesia with etidocaine or bupivacaine. (bjan-sba.org)
  • 22. Greene NM - Challenges and opportunities: the future in regional anesthesia. (bjan-sba.org)
  • Multimodal analgesia, enhanced recovery pathways, and regional anesthesia are key tools as we work towards optimal opioid stewardship and the ideal of effective analgesia without undesirable sequelae. (biomedcentral.com)
  • Regional anesthesia has been widely debated in the literature. (saesp.org.br)
  • This article presents a brief historical overview of regional anesthesia, including critical aspects for its dissemination. (saesp.org.br)
  • In addition, local anesthetics with less neuro and cardiotoxicity and techniques initially guided by electrical stimulation, later followed by ultrasound-guided regional anesthesia, are discussed. (saesp.org.br)
  • 8. Labat G. Regional anesthesia: its technique and clinical application. (saesp.org.br)
  • 12. Volk T, Kubulus C. Regional anesthesia - are the standards changing? (saesp.org.br)
  • The European Society of Regional Anaesthesia and Pain Therapy/American Society of Regional Anesthesia and Pain Medicine recommendations on local anesthetics and adjuvants dosage in pediatric regional anesthesia. (saesp.org.br)
  • Ultrasound-guided regional anesthesia and patient safety: update of an evidence-based analysis. (saesp.org.br)
  • Regional anesthesia complications and contraindications. (saesp.org.br)
  • 17. Hebl JR. The importance and implications of aseptic techniques during regional anesthesia. (saesp.org.br)
  • Brazilian Society of Anesthesiology recommendations for safety in regional anesthesia. (saesp.org.br)
  • Regional anesthesia in the febrile or infected patient. (saesp.org.br)
  • 21. Campos MG, Peixoto AR, Fonseca S, Santos F, Pinho C, Leite D. Assessment of main complications of regional anesthesia recorded in an acute pain unit in a tertiary care university hospital: a retrospective cohort. (saesp.org.br)
  • In a 20-yr-old nulliparous woman, with 4 cm cervical dilatation, 35 min after intrathecal injection, an epidural test dose was administered with the intent to follow with a continuous epidural infusion to maintain uninterrupted analgesia. (silverchair.com)
  • Research in newborn animals has revealed that failure to provide analgesia for pain results in "rewiring" of the nerve path-ways responsible for pain transmission in the dorsal horn of the spinal cord, resulting in increased pain perception of future painful insults. (nysora.com)
  • This confirms human newborn research that found that the failure to provide anesthesia or analgesia for newborn circumcision resulted not only in short-term physiologic perturbations but also in longer-term behavioral changes. (nysora.com)
  • A bolus of 0.125% bupivacaine containing sufentanil, without a previous test dose, proved to be optimal with respect to analgesia and early ambulation. (silverchair.com)
  • Combined spinal-epidural (CSE) analgesia performed with intrathecal opioids (with or without local anesthetic) causes minimal motor block and has been referred to as the "walking epidural. (silverchair.com)
  • Analgesia is one of the main components of anesthesia used during surgical procedures. (umk.pl)
  • In Veterinary Anesthesia and Analgesia (eds K.A. Grimm, L.A. Lamont, W.J. Tranquilli, S.A. Greene and S.A. Robertson). (umk.pl)
  • In obstetric patients, regional analgesia refers to partial or complete loss of pain sensation below the T8 to T10 spinal level. (medscape.com)
  • A report on clinical experiences with spinal analgesia in 100 cases, and some reflections on the procedure. (saesp.org.br)
  • Effect of continuous spinal anesthesia on the hemodynamics of labor analgesia in hypertensive pregnant women: a comparative, randomized clinical trial. (masimo.es)
  • The level of analgesia was recorded continuously using the proprietary index IOC2 (Index of consciousness 2,namely qNOX) (Angel-6000D Multi-parameter Anesthesia Monitor, Shenzhen Weihaokang Medical Technology Co., Ltd, Guangdong, China). (researchgate.net)
  • It has been shown that cholinergic receptors are present in the superficial and deep dorsal horn of the spinal cord, and activation of spinal nicotinic or muscarinic acetylcholine receptors produces analgesia [ 12 ]. (biomedcentral.com)
  • Beginning in the 1960s, a major concern related to body temperature during or immediately following anesthesia was the marked hyperthermia characteristic of the malignant hyperthermia (MH) syndrome. (aneskey.com)
  • Many neuromuscular conditions increase the risk for malignant hyperthermia with anesthesia use, and anticipated surgery should increase the urgency of a diagnostic evaluation. (medscape.com)
  • Furthermore, dantrolene is used to treat spasticity due to spinal cord damage. (ekja.org)
  • Robb LP, Cooney JM, McCrory CR, Evaluation of spinal cord stimulation on the symptoms of anxiety and depression and pain intensity in patients with failed back surgery syndrome. (tcd.ie)
  • These pain impulses are transmitted by afferent, slow conducting, A-delta and C fibers that accompany the sympathetic nerves and enter the spinal cord at the T10 to L1 level. (medscape.com)
  • Neurons expressing gastrin-releasing peptide receptor (GRPR) have been suggested to be responsible for itch sensation in the spinal cord. (biomedcentral.com)
  • Since extracellular signal-regulated kinase (ERK) activation is required for itch sensation in the spinal cord, in this study, we also explored whether ERK1/2 activation is related to morphine-induced pruritus at the molecular level. (biomedcentral.com)
  • These unmyelinated C-fibers transmit itch impulses to the ipsilateral dorsal horn of the spinal cord, 3 where they synapse with itch-specific secondary neurons. (asahq.org)
  • Ascending sensory thermal input is then transmitted to the hypothalamus, the primary thermoregulatory control center of mammals, via the spinal thalamic tracts in the anterior spinal cord. (aneskey.com)
  • Although most thermal information is integrated by the hypothalamus, some processing and response occurs within the spinal cord itself. (aneskey.com)
  • For example, patients with high spinal cord transections have better than expected thermoregulation. (aneskey.com)
  • It interacts with opiate receptors decreasing pain impulse transmission at the spinal cord level and higher in the CNS. (anesthesiaexam.com)
  • Single-dose toxicology studies of EXPAREL (9, 18, and 30 mg/kg), bupivacaine solution (Bsol, 9 mg/kg), and saline injected around the brachial plexus nerve bundle were performed in rabbits and dogs. (hindawi.com)
  • From a systemic standpoint, high doses of bupivacaine may be associated with a wide range of systemic complications, such as central nervous and cardiovascular effects [ 6 ]. (hindawi.com)
  • This study evaluated the influence of bupivacaine bolus concentration and a 3-ml 1.5% lidocaine-epinephrine test dose, on analgesic effectiveness and the ability to walk after block placement. (silverchair.com)
  • and group B.125 received 15 ml bupivacaine, 0.125% (no test dose). (silverchair.com)
  • When a test dose was given before bupivacaine, 0.125%, fewer women walked within 1 h of block placement. (silverchair.com)
  • Omitting a lidocaine-epinephrine test dose and using 0.125% bupivacaine for the initial bolus should permit ambulation in the early postblock period for most parturients who elect this option. (silverchair.com)
  • This study was designed to evaluate analgesic effectiveness and the ability to walk after a bolus of either bupivacaine, 0.0625%, or bupivacaine, 0.125% (with sufentanil), with or without previous administration of the traditional lidocaine-epinephrine test dose. (silverchair.com)
  • 11. Carvalho JCA, Mathias RS, Torres MLA, Brisola N, Gomide do Amaral RV - Effect of baricity on subarachnoid anesthesia with bupivacaine for cesarean section. (bjan-sba.org)
  • 0,5 % bupivacaine, Anesthesiology 81: (Suppl. (pharmapdf.com)
  • Pargger H, Hampl K, Aeschbach A, Paganoni R, Schneider M. Patient's characteristics affecting the spread of isobaric spinal anesthesia with 0,5 % bupivacaine. (pharmapdf.com)
  • Strebel S, Gurzeler JA, Schneider MC, Aeschbach A. Small-dose intrathecal clonidine and isobaric bupivacaine: dose-repsonse study. (pharmapdf.com)
  • Results: IVL has been shown to have a positive effect on reducing opioid doses, postoperative pain intensity, shortening the duration of postoperative bowel obstruction, faster patient rehabilitation and shortening hospitalization. (umk.pl)
  • 1 NMDA receptor interaction with ketamine is thought to play a role in its opioid induced effect of blocking high sensitivity to pain and subanesthetic doses of ketamine via NMDA receptor blockade potentiate opioid analgesia. (empowerpharmacy.com)
  • Intrathecal morphine increased ERK phosphorylation in the lumbar spinal dorsal horn, which may be related with morphine-induced pruritus, and was counteracted by NMDA receptor antagonists. (biomedcentral.com)
  • However, some complications of spinal opioids ( e.g. , respiratory depression, fetal bradycardia, pruritus) may occur more frequently than with current epidural techniques, and some investigators question the need to breach the dura. (silverchair.com)
  • As it relates to anesthesia and the perioperative period, the goal of the anesthesia provider is to minimize deviations in body temperature-unless indicated for specific reasons, such as organ protection-and to determine reasons for any observed deviations in body temperature. (aneskey.com)
  • 1993. Severe abdominal complications after transvaginal ultrasonographically guided retrieval of oocytes for in vitro fertilization and embryo transfer. (nationalacademies.org)
  • In each case, intrathecal sufentanil was administered as part of a combined spinal-epidural technique. (silverchair.com)
  • In cases 4-6, epidural test doses of 1.5% lidocaine with 1:200,000 epinephrine 3 ml were administered at varying times after intrathecal injection. (silverchair.com)
  • 18. Colonna-Romano P, Nagaraj L, Godfrey SD - Epidural test dose and intravascular injection in obstetrics: sensitivity, specificity, and lowest effective dose. (bjan-sba.org)
  • Respiratory rate decreases significantly and end tidal CO2 showeda non significant increase following single doses of epidural fentanyl (1.5 µg/kg). (anesthesiaexam.com)
  • Continuous epidural fentanyl infusion (0.5 µg/kg/hr) started 60 min after the bolus dose had no effect on end tidal CO2 concentration or respiratory rate for up to 18 hours. (anesthesiaexam.com)
  • Spinal infections involve pyogenic or granulomatous infections of the vertebral column, intervertebral discs, the dural sac or the epidural space. (wheelessonline.com)
  • however, this class of analgesics is associated with dose-dependent adverse effects such as nausea, vomiting, ileus, sedation and respiratory depression and prolong the time to readiness for discharge ( 7 , 8 ). (ispub.com)
  • Once sedation or anesthesia begins, they'll stay with you the entire time to monitor your breathing and other vital signs and your comfort level. (asda.org)
  • Ketamine is mainly used in both veterinary and human clinical anesthesia serving as pain killer, sedation in intensive care, and induction of memory loss. (empowerpharmacy.com)
  • to investigate dental patients undergoing sedation using a mean dose of 0.6 mg/kg intravenous midazolam and the adverse events of sedation in patients with ID. (bvsalud.org)
  • This study analyzed the records of 163 dental patients with ID aged between 2 and 76 years who had undergone conscious intravenous sedation (CIV) using a mean dose of 0.61 mg/kg of midazolam at Araçatuba Dental School, São Paulo State University, Brazil. (bvsalud.org)
  • The results of this study showed that CIV is a useful method for dental treatment of patients with ID and these patients can need higher doses of sedative to reach an adequate level of sedation. (bvsalud.org)
  • een anesthetische pleister voor lokale toepassing, die per pleister 70 mg lidocaine en 70 mg tetracaine bevat, verwerkt in een warmteproducerende patch. (richtlijnendatabase.nl)
  • In een dubbelblinde gerandomiseerde studie werden bij het inbrengen van een 16 Gauge katheter bij volwassenen het analgetisch van een lidocaine 70mg/ tetracaine 70 mg zonder en met warmteproducerend effect vergeleken. (richtlijnendatabase.nl)
  • 9] Korevaar et al reported that the minimal toxic dose of local anesthetic injected intravascularly is approximately 4% of the minimum toxic intravenous dose. (medscape.com)
  • Intrathecal injection was performed via a 120-mm (Sprotte) or 127-mm (Gertie Marx) 24-G pencil-point spinal needle (cases 1-5) or a 120-mm 25-G Quincke needle (case 6) introduced via the 18-G needle. (silverchair.com)
  • Compared with control treatment, intrathecal morphine elicited an obvious scratching response and analgesic effect in a dose dependent manner. (biomedcentral.com)
  • In this study, we investigated whether spinal nicotinic or muscarinic receptors play a role in the relieving effects of EA on cold and warm allodynia in the rat tail model of neuropathic pain [ 40 ], using intrathecal (i.t.) administration of selective antagonists. (biomedcentral.com)
  • Anesthesiology December 1999, Vol. 91, 1798. (asahq.org)
  • In non-abdominal surgeries, the greatest benefits have been seen in breast surgery, urology and spinal surgery. (umk.pl)
  • For neuropathic surgery, the right superior caudal trunk was resected at the level between the S1 and S2 spinal nerves innervating the tail. (biomedcentral.com)
  • Three major routes of spread are: (1) hematogenous spread from a distant infection, (2) direct inoculation from trauma, (3) direct inoculation following invasive spinal diagnostic procedures and from spinal surgery. (wheelessonline.com)
  • During anesthesia, thermoregulation is impaired and hypothermia will frequently occur in most patients. (scirp.org)
  • The analgesic effect of N-methyl-D-aspartate (NMDA) receptor antagonists and the morphine-associated increase in NMDA receptor activation suggest potential role of NMDA receptor in the spinal itch sensation. (biomedcentral.com)
  • Fentanyl-O2 anesthesia is an attractive alternative to morphine anesthesia in patients with little cardiac reserve. (anesthesiaexam.com)
  • Anetshetic doses of fentanyl and O2 produce minimal changes in cardiovascular dynamics but that addition of dizepam after large doses of fentanyl results in cardiovascular depression. (anesthesiaexam.com)
  • However, during anesthesia many of these temperature-regulating pathways are interrupted or inhibited. (aneskey.com)
  • However, studies conducted more recently have pointed out that even mild hypothermia, as is often noted during anesthesia, carries physiologic risks. (aneskey.com)
  • Hypothermia affects immunologic activity, bleeding tendency and the recovery from anesthesia. (scirp.org)
  • However, infusion of amino acids is also valuable to prevent hypothermia due to their enhanced thermogenic action under anesthesia. (scirp.org)
  • Its newly discovered neuroprotective, anti-inflammatory and anti-tumor effects and the now-known usefulness of low dose ketamine regimens have helped to expand the clinical application profile of the drug. (empowerpharmacy.com)
  • and mandates that if, as determined by the warden and deputy, the prisoner is not unconscious within 60 seconds after the sodium thiopental's delivery, a new dose will be given at a secondary injection site before the second and third drugs are administered. (justia.com)
  • The median total dose of dantrolene was 400 mg for patients who experienced a muscle weakness complication. (ekja.org)
  • This is to help minimize the need for emergency anesthesia in patients for whom such anesthesia would be especially hazardous. (medscape.com)
  • In another, the belief that pain was useful or that repeated doses of analgesics lead to medication underperformance resulted in the failure of the parents/guardians to provide or ask for prescribed analgesics to treat their children's pain. (nysora.com)
  • Sufentanil, 10 micro gram, diluted to 1 or 2 ml with preservative-free saline, was injected and the spinal needle withdrawn. (silverchair.com)
  • only doses several times higher cause adverse effects. (umk.pl)
  • This study was performed to determine whether spinal cholinergic systems mediate the relieving effects of electroacupuncture (EA) on cold and warm allodynia in a rat model of neuropathic pain. (biomedcentral.com)
  • Neuropathic pain, characterized by spontaneous burning pain, hyperalgesia (an increased response to a stimulus that is normally painful) and allodynia (pain as a result of a stimulus that dose not normally provoke pain), remains one of the most difficult clinical pain syndromes to treat. (biomedcentral.com)
  • an intramuscular dose equivalent to 10 mg per kg body-weight (range 6.5-13 mg/kg) usually produces surgical anesthesia within 3 to 4 minutes lasting for 12 to 25 minutes. (empowerpharmacy.com)
  • A small dose of oral dantrolene does not prolong the duration of action and recovery of rocuronium. (ekja.org)
  • The most common primary spinal infection is pyogenic vertebral osteomyelitis. (wheelessonline.com)
  • Observations on the nature of blood pressure fall with high selective spinal anesthesia in pregnant women. (bjan-sba.org)
  • Spine infections are rare infections that can involve the intervertebral disc space (discitis), the vertebral bones, the spinal canal or adjacent soft tissues. (wheelessonline.com)
  • 04. Barclay DL, Renegar OJ, Nelson EW - The influence of inferior vena cava compression on the level of spinal anesthesia. (bjan-sba.org)
  • Sedative Doses of Midazolam Depress Hypoxic Ventilatory Responses in Humans. (benzo.org.uk)