AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceNamed GroupsHealth CareGeographicals
Rotavirus VaccinesRotavirusRotavirus InfectionsGastroenteritisIntussusceptionVaccines, AttenuatedVaccinesViral VaccinesVaccinationDiarrheaVaccines, InactivatedDiarrhea, InfantileVaccines, CombinedImmunization ScheduleReassortant VirusesAntibodies, ViralFecesCapsid ProteinsVaccines, SyntheticVaccines, DNASafety-Based Drug WithdrawalsBacterial VaccinesImmunization ProgramsNicaraguaAIDS VaccinesAntigens, ViralInfant, NewbornVaccine PotencyAdministration, OralVaccines, ConjugateVaccines, SubunitImmunoglobulin AHospitalizationProduct Surveillance, PostmarketingLatin AmericaDiphtheria-Tetanus-Pertussis VaccineDeveloped CountriesPoliovirus Vaccine, OralVirus SheddingMalaria VaccinesSerotypingVaccines, Live, UnattenuatedImmunization, SecondaryNeutralization TestsPapillomavirus VaccinesGerm-Free LifeSeasonsMeningococcal VaccinesUzbekistanDeveloping CountriesImmunizationHepatitis B VaccinesClinical Trials as TopicMeasles VaccineUnited StatesGenotypeMexicoPertussis VaccineDouble-Blind MethodHaemophilus VaccinesPhiladelphiaPoliovirus Vaccine, InactivatedEnzyme-Linked Immunosorbent AssayBCG VaccineIncidenceRabies VaccinesHospitals, PediatricCost-Benefit AnalysisAdverse Drug Reaction Reporting SystemsCholera VaccinesImmunoglobulin GToxins, BiologicalTyphoid-Paratyphoid VaccinesPlacebosCapsidIndiaSmallpox VaccineAdjuvants, ImmunologicTuberculosis VaccinesMalawiChickenpox VaccineCattleDose-Response Relationship, ImmunologicCost of IllnessMumps VaccineMolecular Sequence DataHepatitis A VaccinesPoliomyelitisMice, Inbred BALB CMeasles-Mumps-Rubella VaccineWorld Health OrganizationDrug LabelingViral Nonstructural ProteinsStreptococcal VaccinesPhylogenyDengue VaccinesAnthrax VaccinesAsiaDrug-Related Side Effects and Adverse ReactionsPopulation Surveillance
VaccinationPneumococcal conjugaRotarixDTaPInfantsIntussusceptionConjugate vaccineMumpsPoliovirus vaccineRotaTeqLive attenuatedHaemophilusHepBTetanusInfluenza vaccineDiseasesUNICEFBoosterVaricellaPolio vaccineEfficacy2023SevereDiarrheaMeasles-containInfectionImmunityHepatitis B vacciChildren under 5 yearsSecond dosePreventionStrainsTdapMonovalentPolysaccharideChickenpoxAntigensImmuneChildhoodOrallyAntibody20202022MRNA COVID-19Human papilloChild'sContraindicationsSerotypesLast doseAdverse effectsRoutine2016COVID-19 Vaccine
Vaccination32
  • Polio was eliminated in the United States with vaccination, and continued use of polio vaccine has kept this country polio-free. (cdc.gov)
  • Last week the World Health Organization recommended that rotavirus vaccination be included in all national immunization programs worldwide. (sciencedaily.com)
  • Although immunization with the human papillomavirus vaccine is recommended for all boys and girls, vaccination rates remain low. (aafp.org)
  • Family physicians should gather accurate information about the harms and benefits of vaccines to advocate for vaccination and decrease the incidence of vaccine-preventable diseases. (aafp.org)
  • 2 , 5 Administration of acetaminophen at the time of vaccination or shortly afterward may alleviate some adverse effects, but there may be a decreased antibody response to some vaccine antigens in children who receive antipyretics. (aafp.org)
  • To further the control of disease by vaccination, we must develop safe and effective new vaccines to combat infectious diseases, and address the public's concerns. (nature.com)
  • Thus, when an adverse event occurs after vaccination, it needs to be determined whether the adverse event was caused by the vaccine or whether it was just coincidental in time with the administration of the vaccine-that is, it was going to happen anyway. (immunizationinfo.org)
  • If symptoms of the disease occurred before vaccination, then the vaccine is not the cause. (immunizationinfo.org)
  • Causation may be inferred if the adverse event or disease only occurs following vaccination and does not occur in persons who did not receive the vaccine. (immunizationinfo.org)
  • For more information, see Rotavirus Advisory Committee on Immunization Practices Vaccine Recommendations and Centers for Disease Control and Prevention (CDC): Rotavirus Vaccination . (msdmanuals.com)
  • The rotavirus vaccine is a routine childhood vaccination (see CDC: Child and Adolescent Immunization Schedule by Age ). (msdmanuals.com)
  • Implementation of the U.S. rotavirus vaccination program reduced the annual proportion of positive rotavirus tests, reduced peak rotavirus activity, and shortened the duration of the rotavirus season. (cdc.gov)
  • Ongoing efforts to improve coverage and on-time vaccination can help maximize the public health impact of rotavirus vaccination. (cdc.gov)
  • To evaluate the long-term impact of rotavirus vaccination on disease prevalence and seasonality in the United States, CDC analyzed national laboratory testing data for rotavirus from laboratories participating in CDC's National Respiratory and Enteric Viruses Surveillance System (NREVSS) during the prevaccine (2000-2006) and postvaccine (2007-2018) periods. (cdc.gov)
  • Data from the first reporting year after vaccine introduction (July 2006-June 2007), which is considered a transitional year with low vaccination coverage, were excluded from the analysis. (cdc.gov)
  • 2 In contrast, vaccination coverage for inactivated polio virus (IPV) and diphtheria, tetanus, and acellular pertussis (DTaP), two long-standing and highly trusted pediatric vaccines, averaged 93% and 84%, respectively, between 2009 and 2017. (health.mil)
  • The present study used the Military Health System (MHS) immunization registry and medical encounter data to assess: 1) rotavirus vaccine coverage relative to IPV and DTaP vaccines and 2) trends in pediatric under vaccination among a population of infants born to female active duty service members. (health.mil)
  • Guidance has been added for administration of 1 or 2 doses of seasonal influenza vaccine based upon the child's history of monovalent 2009 H1N1 vaccination ( 4 ). (cdc.gov)
  • Use of tetanus and diphtheria toxoids, and acellular pertussis (Tdap) vaccine among children aged 7 through 10 years who are incompletely vaccinated against pertussis is addressed, and reference to a specified interval between tetanus and diphtheria toxoids (Td) and Tdap vaccination has been removed ( 5 ). (cdc.gov)
  • [9] Recommendations for when vaccines are administered are based on the age-specific disease risks, age-specific risks for complications, and age-specific vaccination responses, as well as possible effects on the passive maternal-fetal immune response. (medscape.com)
  • The historic reluctance of public health officials to acknowledge that vaccines carry serious risks, which are greater for some people, is one of the biggest impediments to improving the safety of the mass vaccination system. (nvic.org)
  • 84/185 infants (45%) showed an increase in neutralising antibody titre after receiving rotavirus vaccination, compared with 20/91 (22%) of unvaccinated infants. (gla.ac.uk)
  • High maternal antibody levels to rotavirus at the time of vaccination may have reduced the immune response to vaccination. (gla.ac.uk)
  • In anticipation of the development of a successful rotavirus vaccine, factors leading to poor vaccination compliance were investigated. (gla.ac.uk)
  • In 2018, Senegal launched a national human papillomavirus (HPV) vaccination program with Gavi, the Vaccine Alliance (Gavi), support. (cdc.gov)
  • HPV vaccination was incorporated into the national immunization program as a two-dose schedule, with a 6-12-month interval, to nine-year-old girls via routine immunization (RI) services at health facilities, schools and community outreach services throughout the year. (cdc.gov)
  • In children less than 5 years of age, does the vaccination against rotavirus decrease the rate of hospitalizations due to seizures? (evidenciasenpediatria.es)
  • In 2018, they distributed around two million doses of the vaccine Cervarix in Zimbabwe in support of its multi-age cohort vaccination program to protect over 800,000 girls against human papillomavirus and have also supported Gavi pilots of our Cervarix vaccine for human papillomavirus (HPV) in 12 countries since 2012. (globalhealthprogress.org)
  • Governments are more interested in funding vaccination programs after years of neglect, and public fears that vaccines cause harmful side effects are subsiding. (scienceblogs.com)
  • Vaccination campaigns provide additional opportunities for children to receive a few key vaccines, as a way to reach children missed by the routine vaccination system and to provide additional doses to increase immunity to the targeted diseases. (givewell.org)
  • Everyone 6 months and older is recommended to receive 1 dose of the updated COVID-19 vaccine regardless of when you got your last vaccination. (lacounty.gov)
  • Defining surrogate serologic tests with respect to predicting protective vaccine efficacy: Poliovirus vaccination. (who.int)
Pneumococcal conjuga5
  • The pneumococcal conjugate vaccine protects against the bacteria that cause pneumococcal disease. (cdc.gov)
  • Pneumococcal conjugate vaccine, rubella-containing vaccine, measles-containing vaccine second dose, and Haemophilus influenzae type b vaccine have been introduced by 78%, 89%, 94%, and 99% of all countries, respectively. (medscape.com)
  • Information on use of 13-valent pneumococcal conjugate vaccine has been added ( 3 ). (cdc.gov)
  • The pneumococcal conjugate vaccine (PCV) protects against a type of bacteria that can cause ear infections. (tenethealth.com)
  • BACKGROUND: To inform the introduction of pneumococcal conjugate vaccine (PCV) and rotavirus vaccine, the World Health Organization (WHO) established the Global Invasive Bacterial Vaccine-Preventable Disease Surveillance Network (GISN) and the Global Rotavirus Surveillance Network (GRSN) in 2008. (bvsalud.org)
Rotarix17
  • In April 2008, the FDA approved Rotarix, another oral vaccine, for prevention of rotavirus gastroenteritis. (medscape.com)
  • The current recommendation is to administer 2 separate doses of Rotarix to patients aged 6-24 weeks. (medscape.com)
  • Rotarix was efficacious in a large study, which reported that Rotarix protected patients with severe rotavirus gastroenteritis and decreased the rate of severe diarrhea or gastroenteritis of any cause. (medscape.com)
  • However, on March 22, 2010, the FDA recommended the temporary discontinuation of its use, pending further studies on the reported presence of an apparently benign pig virus in the Rotarix vaccine. (medscape.com)
  • In July 2011 he administered the first dose of Rotarix as part of an immunization drive led by the GAVI Alliance. (wikipedia.org)
  • 1 RotaTeq vaccine was approved in 2006 for the prevention of rotavirus gastroenteritis in infants 6 to 32 weeks of age, followed by Rotarix in 2008. (health.mil)
  • Rotarix(R) is a two-dose rotavirus vaccine given to children for the prevention of gastroenteritis caused by rotavirus. (pipelinereview.com)
  • Rotarix(R) is an oral, two-dose, live attenuated vaccine against rotavirus disease in infants that was licensed in 1997 by AVANT Immunotherapeutics to GSK for worldwide commercialization. (pipelinereview.com)
  • Rotarix(R) is the first human rotavirus vaccine derived from a human virus strain available in the market. (pipelinereview.com)
  • Porcine Circovirus type 1 (PCV-1) material has been detected in Rotarix vaccine. (mims.com)
  • The protective efficacy of Rotarix lyophilised formulation against any and severe rotavirus gastro-enteritis was evaluated in Europe, Latin America, Africa and Asia. (mims.com)
  • Protective efficacy in Europe and Latin America: After two doses of Rotarix, the protective vaccine efficacy observed in the studies conducted in Europe and Latin America during the first and second year of life combined is presented in Table 1 and Table 2. (mims.com)
  • Since the immune response observed after 2 doses of Rotarix liquid formulation was comparable to the immune response observed after 2 doses of Rotarix lyophilised formulation, the levels of vaccine efficacy observed with the lyophilised formulation can be extrapolated to the liquid formulation. (mims.com)
  • Protective efficacy in Africa: A clinical study performed in Africa in more than 4,900 subjects evaluated Rotarix given at approximately 10 and 14 weeks of age (2 doses) or 6, 10 and 14 weeks of age (3 doses). (mims.com)
  • After two doses of Rotarix, the protective vaccine efficacy observed up to 3 years of age is presented in table 4. (mims.com)
  • In a clinical study conducted in Africa, the immune response was evaluated in 332 infants who received Rotarix (N=221) or placebo (N=111) according to a 10 and 14 weeks schedule (2 doses) or 6, 10 and 14 weeks schedule (3 doses). (mims.com)
  • Their Rotarix vaccine is available in 36 Gavi countries to protect against rotavirus. (globalhealthprogress.org)
DTaP8
  • A DTaP vaccine is the best protection from three serious diseases: diphtheria, tetanus, and whooping cough (pertussis). (cdc.gov)
  • 3 The fourth dose of the diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine is associated with an increased incidence of fever and injection site reactions compared with the first dose (one in four children). (aafp.org)
  • Diphtheria, tetanus, and pertussis (DTaP) - Five doses protect against all three diseases. (webmd.com)
  • Tetanus, diphtheria, and pertussis (Tdap ) - This is a follow-up shot to the DTaP vaccine kids get when they're younger. (webmd.com)
  • Many of us are familiar with the typical childhood vaccines, including HepB, DTaP, polio and MMR. (aacn.org)
  • Some examples of these types of vaccines are Hib, hepatitis B, HPV and DTaP. (aacn.org)
  • The diphtheria, tetanus and pertussis (DTaP) vaccine, which is three vaccines in one, is given as a series of five shots at two, four and six months, and then usually between 15 and 18 months, as well as between four to six years. (tenethealth.com)
  • To answer that question, Sederdahl et al ( 10.1542/peds.2018-2498 ) analyzed the National Immunization Survey of families with children ages 19-35 months to find out whether opportunities were missed to receive rotavirus vaccine, especially if the family did receive doses of DTaP or MMR vaccine between 6 weeks and 24 months of age. (aap.org)
Infants7
  • Infants younger than 8 months old during RSV season (typically fall through spring) should get a one-dose RSV immunization to protect them against RSV. (cdc.gov)
  • In 2009, an estimated 107 million infants were vaccinated with three doses of diphtheria-tetanus-pertussis vaccine. (who.int)
  • The infants received three doses of ROTAVAC® or a placebo at the ages of 6, 10, and 14 weeks. (path.org)
  • If the government of India decides to introduce the vaccine into the country's Universal Immunization Programme, it will also be made available to all infants in India free of charge. (path.org)
  • BACKGROUND: Despite providing tetanus-toxoid-containing vaccine (TTCV) to infants and reproductive-age women, Uganda reports one of the highest incidences of non-neonatal tetanus (non-NT). (cdc.gov)
  • Sadly, 29% of the 14,571 children were not fully vaccinated against rotavirus but could have been, including 14% of infants and toddlers who received no doses of rotavirus vaccine. (aap.org)
  • We assessed rotavirus vaccine coverage for infants living in Tsu City. (who.int)
Intussusception7
Conjugate vaccine4
  • Meningococcal conjugate vaccine (MCV4) - This protects against four types of meningococcal bacteria that causes meningitis, a disease that affects the brain and spinal cord. (webmd.com)
  • A routine 2-dose schedule of quadrivalent meningococcal conjugate vaccine (MCV4) for certain persons at high risk for meningococcal disease, and recommendations for a booster dose of MCV4 have been added ( 6 ). (cdc.gov)
  • BACKGROUND: In March 2017, Burkina Faso introduced meningococcal serogroup A conjugate vaccine (MACV) into the Expanded Programme on Immunization. (bvsalud.org)
  • Two properly spaced doses of meningococcal conjugate vaccine. (govdelivery.com)
Mumps6
  • The measles, mumps, and rubella vaccine is not associated with autism. (aafp.org)
  • The measles, mumps, and rubella vaccine does not increase the risk of autism and should be routinely used. (aafp.org)
  • Measles, mumps, rubella (MMR ) - Two doses guard against all three of these illnesses. (webmd.com)
  • 1971 - The MMR vaccine is developed by combining the measles vaccine developed in 1963, the mumps vaccine developed in 1967, and the rubella vaccine developed in 1969. (aacn.org)
  • The MMR vaccine protects against measles, mumps and rubella. (tenethealth.com)
  • Make sure your kids' vaccines are up to date to protect them from diseases like measles, mumps, rubella and whooping cough. (lacounty.gov)
Poliovirus vaccine5
  • Inactivated poliovirus vaccine (IPV) - Four doses protect against polio. (webmd.com)
  • The inactivated poliovirus vaccine (IPV) is administered at two and four months of age, and then between six to 18 months and four to six years. (tenethealth.com)
  • Poliovirus vaccine- live. (who.int)
  • Over the past few years we have had frequent requests for the details such as isolation and attenuation and accordingly we felt that bringing the data together in the report below would be both helpful and informative to those involved in the production and control of poliovirus vaccine (oral) prepared from these strains. (who.int)
  • Vaccine- associated paralytic poliomyelitis (VAPP) is a rare adverse event associated with oral poliovirus vaccine (OPV). (who.int)
RotaTeq5
Live attenuated9
Haemophilus7
  • Haemophilus influenzae type b (Hib) - The vaccine protects against a bacteria that causes dangerous brain, lung, and windpipe infections. (webmd.com)
  • 1985 - The first vaccine against Haemophilus influenzae is licensed. (aacn.org)
  • An example is the development of polysaccharide-protein conjugate vaccines against Haemophilus influenzae type b. (nature.com)
  • Guidance for use of Haemophilus influenzae type b (Hib) vaccine in persons aged 5 years and older in the catch-up schedule has been condensed. (cdc.gov)
  • The Hib vaccine helps prevent Haemophilus influenza type B, which can lead to meningitis, pneumonia and a severe throat infection. (tenethealth.com)
  • While in most instances governments pay for the 'traditional' vaccines (BCG, Polio, DTP, Measles), most of the funding for new vaccines (Hepatitis B, Haemophilus Influenzae B, pneumococcal, rotavirus etc) in the poorer countries is provided by the international community through the GAVI Alliance, with recipient governments paying a small part. (givewell.org)
  • Other vaccines that combine DTP and/or Haemophilus influenzae type b and/or hepatitis B with IPV appear feasible but require further investigation. (who.int)
HepB2
  • The hepatitis B (HepB) vaccine is the only shot given to newborns before hospital discharge. (tenethealth.com)
  • He was due for his third and final doses of TDaP, Hib and IPV (pentavalent), HepB, PCV and rotavirus vaccines - only there was no rotavirus vaccine in stock. (defeatdd.org)
Tetanus5
  • In 2017, WHO revised its DTPCV booster recommendations, shifting the first booster dose of tetanus to the second year of life to align with the recommendation for the first booster dose of pertussis. (medscape.com)
  • and diphtheria, tetanus, and acellular pertussis vaccine. (cdc.gov)
  • or tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine. (aafp.org)
  • A booster vaccine called Td is given to prevent tetanus and diphtheria at age 11 or older and then every 10 years throughout life. (tenethealth.com)
  • GAVI has also provided some support for traditional vaccines, including supporting immunization campaigns and outbreak response for measles (see below), providing one-time grants to the Global Polio Eradication Initiative and the Maternal and Neonatal Tetanus Elimination Initiative, and purchasing pentavalent vaccines, which include the DTP vaccine, a traditional vaccine. (givewell.org)
Influenza vaccine3
  • Thimerosal is currently used only in multidose vials of influenza vaccine, and exposure through vaccines is not associated with adverse neurologic outcomes. (aafp.org)
  • 1918 - "Spanish flu" kills one in 67 U.S. soldiers and sparks development of the influenza vaccine. (aacn.org)
  • and Flucelvax, the first cell-culture derived influenza vaccine approved in the U.S., designed to protect adults 18 years and older against seasonal flu. (genengnews.com)
Diseases12
  • In spite of this unprecedented achievement, about 1.5 million children continue to die from vaccine- preventable diseases, nearly 20% of the current annual figure of about 8 million deaths in children under five years. (who.int)
  • Identifying areas of need and responding with evidence-based interventions will allow continued progress in protecting young children against vaccine-preventable diseases. (cdc.gov)
  • Sustained high coverage with recommended vaccinations among children has kept many vaccine-preventable diseases at low levels in the United States ( 1 ). (cdc.gov)
  • The diseases that vaccines prevent are often more serious for babies and young children than they are for adults. (webmd.com)
  • Currently, over 20 diseases can be prevented with vaccines, and over a dozen more are being developed. (aacn.org)
  • However, in developed countries, the public's fear of vaccine-preventable diseases has waned, and awareness of potential adverse effects has increased, which is threatening vaccine acceptance. (nature.com)
  • In the ensuing years, vaccines for more than 20 infectious diseases have been developed, and in 1977, Jenner's original experiment was brought to full fruition when smallpox was eradicated worldwide 6 . (nature.com)
  • Routine use of these vaccines has nearly eliminated meningitis and other diseases caused by H. influenzae type b 6 . (nature.com)
  • Vaccines are unique among medical interventions in that they are given to healthy individuals to prevent diseases that often do not pose an immediate threat to the recipient. (nature.com)
  • Vaccines protect people of all ages from serious infectious diseases. (guthrie.org)
  • So are vaccines for such vexing diseases as AIDS, a big killer whose variety and rapid mutations pose hard problems for vaccine makers. (scienceblogs.com)
  • Vaccines are really important in stopping infectious diseases from spreading, and they help our community stay healthy and strong. (lacounty.gov)
UNICEF4
  • According to the CDC, UNICEF and WHO, vaccines prevent between 2 million and 4 million childhood deaths each year. (aacn.org)
  • Once prequalified, the vaccine could be purchased by UNICEF and the Pan American Health Organization as a vaccine offered to countries eligible for receiving subsidized vaccines from the GAVI Alliance. (path.org)
  • GSK is the largest supplier of vaccines to UNICEF which purchases vaccines on behalf of Gavi. (globalhealthprogress.org)
  • This video from UNICEF shows a side-by-side comparison of two mothers whose access to vaccines looks completely different. (defeatdd.org)
Booster8
  • Kids need their first dose at age 11 or 12 and a booster dose at age 16. (webmd.com)
  • Prime-boost vaccine regimens involve an initial dose that primes the immune system to develop disease-specific antibodies, followed by a booster dose at a later date that can strengthen and optimize the duration of the immune response. (jnj.com)
  • Pfizer to Ask US Regulators to Authorize COVID Vaccine Booster for 5-11 Age Group. (nvic.org)
  • The high CFR and high non-NT burden among men and older children indicate the need for TTCV booster doses across the life course to all individuals as well as improved coverage with the TTCV primary series. (cdc.gov)
  • Would a booster dose be advisable? (evidenciasenpediatria.es)
  • Your child should not receive a booster vaccine if he or she had a life threatening allergic reaction after the first shot. (everydayhealth.com)
  • When the child receives a booster dose, you will need to tell the doctor if the previous shot caused any side effects. (everydayhealth.com)
  • Different brands of this vaccine may not have the same dosing or booster schedule. (everydayhealth.com)
Varicella5
  • As new vaccines, such as varicella, pneumococcal conjugate, and rotavirus have been recommended by the Advisory Committee on Immunization Practices, the National Immunization Survey (NIS) has been able to provide important information on vaccine coverage among U.S. children aged 19-35 months and on progress toward meeting coverage targets. (cdc.gov)
  • Varicella (chickenpox) - Kids need two doses, spaced out about 4-5 years. (webmd.com)
  • The varicella vaccine is given to protect children against chickenpox. (tenethealth.com)
  • and varicella (≥1 dose). (medscape.com)
  • those with varicella disease or who received ≥2 doses of the vaccine). (medscape.com)
Polio vaccine4
  • 1952-1955 - The first effective polio vaccine is developed. (aacn.org)
  • The vaccine was well tolerated when administered with other childhood vaccines, including oral polio vaccine. (path.org)
  • No effect from the concurrent administration of oral polio vaccine on the immune response to rotavirus vaccine was observed. (gla.ac.uk)
  • Lower type 1 and type 3 polio antibody levels were found in children who received oral polio and rotavirus vaccines than those who received oral polio vaccine and placebo but differences between the two groups were not statistically significant. (gla.ac.uk)
Efficacy9
  • The medical journal The Lancet today published results from a phase 3 efficacy trial of ROTAVAC® , a new rotavirus vaccine developed in India. (path.org)
  • The vaccine's efficacy compares favorably with the efficacy of the currently licensed rotavirus vaccines in low-resource countries. (path.org)
  • Clinical trials have shown high efficacy against the most prevalent rotavirus strains. (pipelinereview.com)
  • But there is no substantial evidence of efficacy for ETEC and shigella vaccines, although several promising vaccine concepts are moving from the development and testing pipeline towards efficacy and Phase 3 trials. (biomedcentral.com)
  • Older generation injectable cholera vaccines have been abandoned since the 1970s owing to their limited efficacy and local side effects. (biomedcentral.com)
  • A pooled analysis of four efficacy studies, showed a 71.4% (95% CI: 20.1;91.1) efficacy against severe gastro-enteritis (Vesikari score ≥11) caused by rotavirus G2P[4] strain. (mims.com)
  • The vaccine efficacy against severe rotavirus gastro-enteritis during the first year of life was 61.2% (95% CI: 44.0;73.2). (mims.com)
  • The study was not powered to evaluate a difference in vaccine efficacy between the 2- and 3-dose regimens. (mims.com)
  • The protective vaccine efficacy observed against any and severe rotavirus gastro-enteritis is presented in Table 3. (mims.com)
20232
  • Four syringes that contained expired vaccine doses in Thanh Hoa in central Vietnam, May 9, 2023. (vnexpress.net)
  • By 10 a.m. the same day, some families reported that certain 6-in-1 vaccine shots had their expiration dates listed as March 2023. (vnexpress.net)
Severe12
  • Rotavirus can cause severe diarrhea, which can lead to dehydration . (kidshealth.org)
  • But each year an estimated two million children are hospitalized because rotavirus infection results in severe dehydration caused by diarrhea and vomiting. (sciencedaily.com)
  • In follow-up to a May 2013 announcement about the study's early results, the article includes more detailed data from the phase 3 study, which showed that ROTAVAC® significantly reduced severe rotavirus diarrhea by more than half-56 percent during the first year of life, with protection continuing into the second year of life. (path.org)
  • Before the introduction of rotavirus vaccine in the United States in 2006, rotavirus infection was the leading cause of severe gastroenteritis among U.S. children. (cdc.gov)
  • A severe allergic reaction which occurs suddenly, usually within 15 minutes, however anaphylaxis can occur within hours of vaccine administration. (health.gov.au)
  • Rotavirus vaccine is used to gain a shield and protect against rotavirus infections which cause severe diarrhea among young children as a part of the population. (marketresearchfuture.com)
  • The market symptoms of rotavirus infection are inclusive of severe diarrhea, vomiting, fever, and abdominal pain which can result in disease. (marketresearchfuture.com)
  • Rotavirus vaccine is known to be applied to gain prevention against rotavirus infections which can cause severe diarrhea that is more prevalent amongst young children. (marketresearchfuture.com)
  • The symptoms of rotavirus infection are inclusive of severe diarrhea, and other issues like vomiting, fever, and abdominal pain. (marketresearchfuture.com)
  • Rotavirus is the most common cause of severe dehydrating diarrhea in young children globally accounting for an estimated 527,000 (475 000-580 000) deaths each year, mostly in children under the age of two years [ 2 ]. (biomedcentral.com)
  • Rotavirus diarrhoea was more severe than diarrhoea due to all other causes and clinical rotavirus infection was associated with weight loss in the post-infection period. (gla.ac.uk)
  • In the case of a more severe illness with a fever or any type of infection, wait until the child gets better before receiving this vaccine. (everydayhealth.com)
Diarrhea11
Measles-contain1
  • MACV is administered to children aged 15-18 months, concomitantly with the second dose of measles-containing vaccine (MCV2). (bvsalud.org)
Infection10
  • Immunosuppressives may diminish therapeutic effects of vaccines and increase risk of adverse effects (increased risk of infection). (medscape.com)
  • The Salmonella typhi vaccine is recommended for travelers to countries with a high risk of this infection, persons with intimate exposure to a documented typhoid fever carrier, and workers with frequent exposure to this bacteria. (medscape.com)
  • The images could help scientists design a more effective vaccine against rotavirus, a lethal infection that kills more than 500,000 children worldwide each year. (sciencedaily.com)
  • Vaccines (eg, rotavirus) can help increase resistance to infection. (medscape.com)
  • Some young children (especially aged 1-3 years) are more prone to seizures when experiencing a high fever from any source (with an infection or after a vaccine). (health.gov.au)
  • The human rotavirus vaccine market has been one of the affected markets since the coronavirus infection has turned into a pandemic and is facing adversities ever since. (marketresearchfuture.com)
  • This thesis reports the results of these studies and places them in the context of current knowledge concerning the epidemiology and immunology of rotavirus infection. (gla.ac.uk)
  • A case-control study was conducted on 92 cases and 92 age and vaccine status matched controls to determine social and environmental risk factors for rotavirus infection. (gla.ac.uk)
  • This vaccine will not treat an active infection that has already developed in the body. (everydayhealth.com)
  • In one pre-vaccine year (2010-2011), the number of outpatient visits due to the rotavirus infection was 66. (who.int)
Immunity11
  • Virtually every child in the world becomes infected with rotaviruses before developing natural immunity. (sciencedaily.com)
  • Both natural and vaccine-induced immunity occur only after the immune system has "seen" the virus and generates neutralizing antibodies. (sciencedaily.com)
  • They require several doses to provide full immunity. (aacn.org)
  • They create a strong, lasting immunity and often require only one or two doses. (aacn.org)
  • Messenger RNA (mRNA) vaccines make proteins that trigger an immune response in the host, so the host can mount immunity against the pathogen. (aacn.org)
  • Advances in our understanding of the determinants of protective immunity and immunological memory, of the mechanisms by which adjuvants affect the quality and magnitude of immunological responses, and of microbial genomics, offer the promise for new and more effective vaccines in the near future. (nature.com)
  • Overview of Immunization Immunity can be achieved Actively by using antigens (eg, vaccines, toxoids) Passively by using antibodies (eg, immune globulins, antitoxins) A toxoid is a bacterial toxin that has been modified. (msdmanuals.com)
  • The factors contributing to the growth of the human rotavirus vaccine market include increased development alongside an increase in the number of people with weakened immunity. (marketresearchfuture.com)
  • A number of widely used vaccines use a multi-dose approach to create stronger and longer-lasting immunity, including some for polio, rotavirus and HPV. (jnj.com)
  • This vaccine works by exposing your child to a small dose of the virus, which causes the body to develop immunity to the disease. (everydayhealth.com)
  • New combination vaccines should induce similar or superior levels of neutralizing antibody in serum for individual protection against paralytic disease and mucosal immunity that effectively decreases viral replication in the intestine and pharynx for population protection against transmission of poliovirus. (who.int)
Hepatitis B vacci1
  • Guidance has been added for the hepatitis B vaccine schedule for children who did not receive a birth dose ( 2 ). (cdc.gov)
Children under 5 years2
Second dose4
  • Similarly, if your child had their first dose of MMR as a baby, but they are not yet old enough to have received their second dose, they are up to date and there is no need to have the second MMR dose earlier than scheduled. (wales.nhs.uk)
  • The second dose is six to 18 months later. (tenethealth.com)
  • 20 U/ml (by ELISA)) with serum anti-rotavirus IgA antibody titers ≥ 20U/ml one or two months after the second dose of vaccine or placebo ranges from 77.9% to 100% and from 0% to 17.1% respectively. (mims.com)
  • The second dose is required prior to entry to the twelfth grade. (govdelivery.com)
Prevention4
  • 2021 - A third-generation smallpox vaccine is approved for the prevention of Mpox (then known as monkeypox). (aacn.org)
  • Below is a recommended list of vaccines and timing for children from birth to 18 years, according to the Centers for Disease Control and Prevention (CDC). (guthrie.org)
  • Between June 1984 and June 1986 a variety of studies on rotavirus diarrhoea and its prevention were conducted in Bakau, a peri-urban Gambian community. (gla.ac.uk)
  • As wealthy countries spend much more on health care, and as poorer countries put new emphasis on disease prevention, many companies are jumping into vaccine innovation, including major pharmaceutical makers like Astra Zeneca, Novartis and Pfizer. (scienceblogs.com)
Strains4
  • Rotavirus strains detected at Queen Elisabeth Central Hospital during January 2013-December 2015. (cdc.gov)
  • This vaccine is updated from time to time to protect against the latest strains of the virus. (lacounty.gov)
  • History of Sabin attenuated poliovirus oral live vaccine strains. (who.int)
  • The ful data concerning the history of attenuated poliovirus strains developed by one of us (Sabin, 1965) for vaccine production do not appear in a single journal. (who.int)
Tdap1
  • Some vaccines such as the Tdap require boosters at certain intervals. (aacn.org)
Monovalent3
  • A Cochrane Database review evaluated the results of 43 trials with 190,551 participants comparing rotavirus vaccines, both the monovalent and pentavalent types (RV1 and RV5), with placebo. (medscape.com)
  • Currently, two oral vaccines, monovalent and pentavalent vaccines are available. (who.int)
  • Monovalent rotavirus vaccine is administered orally in a two-dose schedule while pentavalent Rotavirus vaccine is administered orally in a three-dose schedule. (who.int)
Polysaccharide1
  • Subunit, recombinant, polysaccharide and conjugate vaccines use pieces of the pathogen, such as its protein, sugar or capsid to create an immune response against the pathogen. (aacn.org)
Chickenpox1
  • The chickenpox vaccine was not widely used when I was a child, and I remember "chickenpox parties" in which my mom and her friends would gather us all together when one child got chickenpox. (aacn.org)
Antigens1
Immune12
  • Rotavirus vaccine can be administered together with other EPI vaccines with no interference with the immune response. (who.int)
  • These soldiers of the immune system seek out and attach to rotavirus particles, rendering them unable to infect cells. (sciencedaily.com)
  • A vaccine helps your immune system build the tools, called antibodies, it needs to fight viruses and bacteria that cause illnesses. (webmd.com)
  • The age when a vaccine works best in the immune system. (webmd.com)
  • Vaccines are an instruction manual for our immune system on how to fight certain pathogens. (aacn.org)
  • AVANT Immunotherapeutics, Inc. discovers and develops innovative vaccines and therapeutics that harness the human immune system to prevent and treat disease. (pipelinereview.com)
  • Background: Neutralizing antibodies in breast milk may adversely influence the immune response to live oral vaccines. (uib.no)
  • Vaccines work by taking weakened or killed versions of bacteria or viruses and then stimulating the immune system to create antibodies that will fight possible exposure in the future. (tenethealth.com)
  • Factors that affect the optimal response to a vaccine include the vaccine type and the recipient's age and immune status. (medscape.com)
  • In addition, naturally circulating enteroviruses may have interfered with the immune response to the rotavirus vaccine. (gla.ac.uk)
  • For up to 15 days after receiving rotavirus vaccine , the child should avoid coming into contact with anyone who has a weak immune system. (everydayhealth.com)
  • Vaccines actually train your immune system to be stronger. (lacounty.gov)
Childhood4
  • Vaccines are one of the most effective means of preventing childhood disease and death. (aacn.org)
  • The National Childhood Vaccine Injury Act requires that health-care providers provide parents or patients with copies of Vaccine Information Statements before administering each dose of the vaccines listed in the schedules. (cdc.gov)
  • Currently, only 85% of children worldwide, and 77% of children in Africa, receive the recommended set of childhood vaccines. (givewell.org)
  • Most vaccines don't have any mercury and thimerosal, a form of mercury, was removed from all childhood vaccines in 2001. (lacounty.gov)
Orally2
  • Rotavirus vaccines are given orally by putting drops in the infant's mouth. (msdmanuals.com)
  • RV5 is given orally in 3 doses, one dose at age 2 months, 4 months, and 6 months. (msdmanuals.com)
Antibody3
  • In the new experiments, Howard Hughes Medical Institute (HHMI) researchers have mapped the structure of an antiviral antibody clamped onto a protein called VP7 that stipples the surface of rotavirus. (sciencedaily.com)
  • Prevaccination rotavirus neutralising antibody levels were high. (gla.ac.uk)
  • Another possibility is that Gambian breast milk contains anti-rotavirus antibody or nonantibody factors which inhibited the vaccine response. (gla.ac.uk)
20205
  • The annual rate of new vaccine introductions declined precipitously when the COVID-19 pandemic started, from 48 in 2019 to 15 in 2020 before rising to 26 in 2021. (medscape.com)
  • 2020 - The first doses of the mRNA COVID-19 vaccine are administered. (aacn.org)
  • The expired doses were produced in April 2020. (vnexpress.net)
  • If we are to achieve the Healthy People 2020 goal of vaccinating 80% of the children in this country against rotavirus, we need to inject more time and attention into educating families about the importance of this vaccine and the minimal if any minor side effects of giving it to children. (aap.org)
  • For example, GlaxoSmithKline's (GSK) oral rotavirus vaccine in unit-dose BFS containers was designed in collaboration with global health organization PATH and used for the first time in February 2020 in an immunization program in Myanmar (1). (biopharminternational.com)
20224
  • an alternative single-dose schedule was recommended in 2022 for girls aged 9-14 years. (medscape.com)
  • The human rotavirus vaccine market revenue is likely to reach a final value worth Significant Value for the ongoing forecast period of 2022-2030. (marketresearchfuture.com)
  • . The Vaccine Reaction Aug. 7, 2022. (nvic.org)
  • Tran Anh Nam, director of the Nong Cong center, said the expired vaccine doses were among the 165 doses purchased from the Hanoi Pharmaceutical and Medical Equipment company on May 23, 2022. (vnexpress.net)
MRNA COVID-191
  • FDA should immediately release all information related to the incidence of myocarditis and other serious adverse events following mRNA COVID-19 vaccinations, whether that information has been provided to the agency by vaccine manufacturers or discovered through in-house analyses of additional data collected by federal officials. (nvic.org)
Human papillo3
  • The most common adverse effects of the human papillomavirus vaccine are transient and similar to those of other vaccines, including mild pain and bruising at the injection site, headache, lightheadedness, and syncope. (aafp.org)
  • Two doses of properly spaced human papillomavirus vaccine for all children. (govdelivery.com)
  • Multilevel Implementation Strategies for Adolescent Human Papillomavirus Vaccine Uptake: A Cluster Randomized Clinical Trial. (mayo.edu)
Child's6
  • Read the Vaccine Information Sheet(s) your child's doctor gave you to learn about side effects your child may experience. (cdc.gov)
  • Routine wellness visits that include vaccines are another important way to protect your child's health. (webmd.com)
  • You should discuss your child's health with your pediatrician to determine exact timing and number of doses. (guthrie.org)
  • No risk factors were found but there was an association between rotavirus cases and the presence of a dog in the child's compound. (gla.ac.uk)
  • Becoming infected with rotavirus is much more dangerous to your child's health than receiving this vaccine. (everydayhealth.com)
  • For oral delivery to young children, for example, the GSK rotavirus vaccine container was designed with a longer, narrow tube for the opening so that it would fit well inside the child's cheek. (biopharminternational.com)
Contraindications1
  • While vaccines are universally recommended, some children may have contraindications to particular vaccines. (who.int)
Serotypes1
  • Interference among the three attenuated poliovirus serotypes was minimized with a 'balanced- formulation' vaccine, and serologic responses after IPV were optimized by adjusting the antigenic content of each inactivated poliovirus serotype. (who.int)
Last dose2
  • The maximum age for administering the last dose of the vaccine is recommended to be at 32 weeks of age. (who.int)
  • On Tuesday, June 23rd, the author did go back, and her son got his last dose of the rotavirus vaccine. (defeatdd.org)
Adverse effects2
  • Because of this, parents are increasingly questioning the necessity of immunizing their children, especially because no vaccine is completely free of adverse effects or the risk of complications. (aafp.org)
  • Some parents express concern that physicians are not well educated on the adverse effects of vaccines or that physicians purposefully withhold information on adverse effects. (aafp.org)
Routine4
  • See which vaccines your child needs to stay on-track with routine vaccinations. (cdc.gov)
  • IA2030, endorsed by the World Health Assembly, includes a target to achieve 500 new and underutilized vaccine introductions in low-income and middle-income countries' routine immunization schedules by 2030. (medscape.com)
  • Year WHO recommended inclusion of vaccine in all national routine immunization programs. (medscape.com)
  • Routine vaccine delivery systems. (givewell.org)
20162
  • Vaccine introduction data for DTPCV4 was unavailable for 2016. (medscape.com)
  • Available at http://www.who.int/biologicals/vaccines/BS2185_OPV_Post_ECBS_DB_TZ_DBFinal12Feb2013.pdf, accessed February 2016. (who.int)
COVID-19 Vaccine3
  • The COVID-19 vaccine is an mRNA vaccine. (aacn.org)
  • FDA Removes Document On Moderna Vaccine Approval From Website After Conservative Media Asks Questions - With the removal by the FDA of a document providing the public with insight into the decision to approve Moderna's COVID-19 vaccine, NVIC's Barbara Loe Fisher stated the public has the right to review the evidence FDA is using to license new mRNA vaccines as safe and effective. (nvic.org)
  • While the CDC recommends the use of the Pfizer-BioNTech COVID-19 Vaccine for children age 12 and up, Virginia state law does not require COVID-19 vaccines for enrollment in public schools. (govdelivery.com)