• Genome
  • We propose that chromocenter and satellite DNA serve a fundamental role in encapsulating the full complement of the genome within a single nucleus, the universal characteristic of eukaryotic cells. (elifesciences.org)
  • The double FISH analysis of two repetitive DNAs (a satellite DNA and ribosomal DNA) in 12 natural populations of the grasshopper Eyprepocnemis plorans collected at the south (Granada and Málaga provinces) and south-east (Albacete and Murcia provinces) of the Iberian Peninsula has shown their widespread presence throughout the whole genome as well as extensive variation among populations. (springer.com)
  • 1998) Repetitive DNA sequences in the common vole: cloning, characterization andch romosome localization of two novel complex repeats MS3 and MS4 from the genome of the East European vole Microtus rossiaemeridionalis. (springer.com)
  • Early in her career Frommer investigated the molecular biology of "satellite DNAs" in the human genome. (wikipedia.org)
  • A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA. (wikipedia.org)
  • Although Group VII viruses such as hepatitis B contain a DNA genome, they are not considered DNA viruses according to the Baltimore classification, but rather reverse transcribing viruses because they replicate through an RNA intermediate. (wikipedia.org)
  • A group known as the pleolipoviruses, although having a similar genome organisation, differ in having either single or double stranded DNA genomes. (wikipedia.org)
  • The symbiotic relationship between a satellite and a helper virus to catalyze the replication of a satellite viral genome is also dependent on the host to provide components like replicases to carry out replication. (wikipedia.org)
  • The emergence of Satellite RNA is said to have come from either the genome of the host or its co-infecting agents, and any vectors leading to transmission. (wikipedia.org)
  • Some research suggest that MSIs are short tandem DNA repeat sequences of one to six base pairs throughout the genome, while other research suggests that the range may be two to five. (wikipedia.org)
  • Microsatellites make up approximately three percent of the human genome, or more than one million fragments of DNA. (wikipedia.org)
  • The genome is a single circular single strand DNA molecule. (wikipedia.org)
  • Singh founded various institutes and laboratories in India, including the Centre for DNA Fingerprinting and Diagnostics in 1995, Laboratory for the Conservation of Endangered Species (LaCONES) in 1998, and Genome Foundation in 2004, aiming to diagnose and treat genetic disorders affecting the Indian population, in particular the under-privileged people residing in rural India. (wikipedia.org)
  • DNAs
  • Satellite DNAs are heterogeneous and no general function has been attributed to this DNA class. (scielo.br)
  • Moreover, satellite DNAs are involved in the maintenance of functional centromeres in mammals (Willard, 1990) and might also be related to the late replication of centromeres (Csink and Henikoff, 1998). (scielo.br)
  • No obvious satellite DNAs were resolved using the CsCl or Ag-Cs 2 SO 4 density gradient conditions described herein. (springer.com)
  • DNAs from several highly (≥ hundredfold increased resistance) antifolate-resistant sublines of DC-3F, characterized by a large homogeneously staining region (HSR) in the chromosome complement, were examined with both techniques and compared to the parental, antifolate-sensitive cell line DNA. (springer.com)
  • Molecular
  • Before his term as Vice Chancellor of Banaras Hindu University, he also served as director of the Centre for Cellular and Molecular Biology (CCMB) from May 1998 to July 2009 and Officer on Special Duty (OSD) of Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India in 1995-1999. (wikipedia.org)
  • viral
  • In 1986, the first hammerhead ribozymes were found in some RNA plant pathogens like viroids and viral satellites. (wikipedia.org)
  • Satellite viral particles should not be confused with satellite DNA. (wikipedia.org)
  • A satellite virus important to human health that demonstrates the need for co-infection to replicate and infect within a host is Hepatitis D. Hepatitis D (HDV) was discovered in 1977 by an Mario Rizzetto and is unique from Hepatitis A, B, and C because it requires viral particles from Hepatitis B to replicate and infect liver cells. (wikipedia.org)
  • Hepatitis Delta Virus is found all over the globe but most Prevalent in Africa, the Middle East and Southern Italy Satellite viruses- satellites are classified as sub viral agents in that they require the help for co-infection therefore they do not have their own taxonomic classification. (wikipedia.org)
  • HACs allow for delivery of more DNA (including promoters and copy-number variation) than is possible with viral vectors. (wikipedia.org)
  • PROTEIN
  • A kinetic study of DNA and basic protein metabolism during spermatogenesis in the sand crab, Emerita analoga. (springer.com)
  • It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. (genecards.org)
  • Satellite viruses, which are most commonly associated with plants, but are also found in mammals, arthropods, and bacteria, have the components to make their own protein shell to enclose their genetic material, but rely on a helper virus to replicate. (wikipedia.org)
  • Scientists discovered that the first satellite had the components to make its own protein shell. (wikipedia.org)
  • proteins
  • Specifically, DNA polymerase slips, creating a temporary insertion-deletion loop, which is usually recognized by MMR proteins. (wikipedia.org)
  • Many of these proteins are conserved between eukaryotic species, including a specialized histone H3 variant (called CENP-A or CenH3) which helps the kinetochore associate with DNA. (wikipedia.org)
  • The deepest layer in the kinetochore is the inner plate, which is organized on a chromatin structure containing nucleosomes presenting a specialized histone (named CENP-A, which substitutes histone H3 in this region), auxiliary proteins (= helper proteins) and DNA. (wikipedia.org)
  • microsatellite
  • On southern blots hybridized to a satellite III probe, relative intensities of Hinf1 fragments correlated with the taurine-zebu composition in hybrid animals as deduced from AFLP genotyping of the same animals and previous data on microsatellite allele frequencies. (cgiar.org)
  • molecules
  • In addition, all isolates were found to be associated with DNAβ molecules. (deepdyve.com)
  • these molecules had an ORF βC1, an adenine-rich region, and a satellite conserved region. (deepdyve.com)
  • In 1998 Frommer realised that it should be possible to amplify the products of a DNA deamination reaction and distinguish methylated and unmethylated molecules by dideoxy-sequencing. (wikipedia.org)
  • The PCR products of bisulphite reactions could be sequenced directly to measure the extent of methylation at any CpG site in a population of DNA molecules. (wikipedia.org)
  • Moreover
  • Moreover, DNA conformational features can be linked to both similarities and distinctions in platinum drug adduct formation between the naked and nucleosomal DNA states. (rcsb.org)
  • loci
  • Some researchers believe that the oxidative stress on specific loci results in DNA polymerase pausing at those sites, creating an environment for DNA slippage to occur. (wikipedia.org)
  • viruses
  • DNA viruses belong to either Group I or Group II of the Baltimore classification system for viruses. (wikipedia.org)
  • Notable diseases like smallpox, herpes, and the chickenpox are caused by such DNA viruses. (wikipedia.org)
  • A fourth order-Megavirales-for the nucleocytoplasmic large DNA viruses has been proposed. (wikipedia.org)
  • A recently proposed clade is the Megavirales which includes the nucleocytoplasmic large DNA viruses. (wikipedia.org)
  • However, the usage of this term remains controversial due to the lack of fundamental differences between virophages and classical satellite viruses. (wikipedia.org)
  • Virophages or satellite viruses? (wikipedia.org)
  • These viruses were earlier known as DNA 1 components. (wikipedia.org)
  • vitro
  • Genotoxic effects of ethyl methanesulfonate and X-rays at different stages of rat spermatogenesis, studied by inhibition of DNA synthesis and induction of DNA repair in vitro. (springer.com)
  • fingerprint
  • Although the length of these microsatellites is highly variable from person to person and contributes to the individual DNA "fingerprint", each individual has microsatellites of a set length. (wikipedia.org)
  • Drosophila
  • We characterized sequences of a novel SSS139 Rsa I satellite DNA family in Drosophila gouveai and Drosophila seriema , two members of the Drosophila buzzatii cluster ( D. repleta group). (scielo.br)
  • interphase
  • Defective chromocenter formation leads to micronuclei formation due to budding from the interphase nucleus, DNA damage and cell death. (elifesciences.org)
  • species
  • Junk DNA' therefore appears to participate in fundamental cellular processes across species, a result that opens up several new lines of research. (elifesciences.org)
  • 2001) Chromosomal location andev olution of a satellite DNA family in sevensturge on species. (springer.com)
  • Three satellite DNA families were identified in three species of burying beetles, Nicrophorus orbicollis, N. marginatus, and N. americanus. (umd.edu)
  • density gradient
  • The density gradient profiles and electrophoretic patterns of restriction endonuclease digests were identical among all the cell lines examined and were indistinguishable from those of the parental DC-3F DNA. (springer.com)
  • variation
  • We describe satellite DNA variation that detects hybridization of Bos indicus (Zebu or indicine cattle) and Bos taurus (taurine cattle) in African cattle populations. (cgiar.org)
  • RNAs
  • Named for the resemblance of early secondary structure diagrams to a hammerhead shark, hammerhead ribozymes RNAs were originally discovered in two classes of plant virus-like RNAs: satellite RNAs and viroids. (wikipedia.org)
  • chromatin
  • These findings illuminate DNA structure-dependent reactivity and provide a novel framework for understanding metal-double helix interactions, which should facilitate the development of improved chromatin-targeting medicinal agents. (rcsb.org)