• Myoclonus is a brief, involuntary, irregular (lacking rhythm) twitching of a muscle, a joint, or a group of muscles, different from clonus, which is rhythmic or regular. (wikipedia.org)
  • For instance, some opioids have been shown to cause myoclonus , which causes regular hiccups, increased likelihood of sensitivity to external stimuli such as noise and involuntary body spasms. (herbalsuite.com)
  • and a sarcoidosis-like syndrome with mediastinal lymph nodes and central nervous system (CNS) involvement (ie, dementia, sensory and motor deficits, ophthalmoplegia, myoclonus, stroke and hypothalamic damage with dysautonomia, emotional impairment, endocrinopathy). (medscape.com)
  • Cortical reflex myoclonus is thought to be a type of epilepsy that originates in the cerebral cortex - the outer layer, or "gray matter", of the brain, responsible for much of the information processing that takes place in the brain. (wikipedia.org)
  • Essential myoclonus occurs in the absence of epilepsy or other apparent abnormalities in the brain or nerves. (wikipedia.org)
  • Some scientists speculate that some forms of essential myoclonus may be a type of epilepsy with no known cause. (wikipedia.org)
  • Progressive myoclonus epilepsy (PME) is a group of diseases characterized by myoclonus, epileptic seizures, tonic-clonic seizures, and other serious symptoms such as trouble walking or speaking. (wikipedia.org)
  • A disorder characterized by the onset of myoclonus in adolescence, a marked increase in the incidence of absence seizures (see EPILEPSY, ABSENCE), and generalized major motor seizures (see EPILEPSY, TONIC-CLONIC). (lookformedical.com)
  • Lafora disease is characterized by myoclonus, epileptic seizures, and dementia (progressive loss of memory and other intellectual functions). (wikipedia.org)
  • A second group of PME diseases belonging to the class of cerebral storage diseases usually involves myoclonus, visual problems, dementia, and dystonia (sustained muscle contractions that cause twisting movements or abnormal postures). (wikipedia.org)
  • Due to their tendency to alter the brain's chemical composition, drugs may result in distorted coordination and cognitive function. (herbalsuite.com)
  • These myoclonic twitches, jerks, or seizures are usually caused by sudden muscle contractions (positive myoclonus) or brief lapses of contraction (negative myoclonus). (wikipedia.org)
  • Essential myoclonus tends to be stable without increasing in severity over time. (wikipedia.org)
  • The grand burqa cannot distort as the essential truth-finding tool it is if witnesses can lie with topography. (angelfire.com)
  • These substances also distort the element of time, which causes users to forget about dietary structure. (herbalsuite.com)
  • Cortical reflex myoclonus is thought to be a type of epilepsy that originates in the cerebral cortex - the outer layer, or "gray matter", of the brain, responsible for much of the information processing that takes place in the brain. (wikipedia.org)
  • Cortical reflex myoclonus can be intensified when patients attempt to move in a certain way or perceive a particular sensation. (wikipedia.org)
  • The substantial reduction in SICI suggests that both ULD and LBD patients have impaired inhibitory interneuron pools which are involved in the generation of cortical reflex myoclonus, whereas the inhibition found in LBD patients at ISI 6 and 10 ms, as well the reduced inhibition found at long intervals, suggest a more complex circuitry dysfunction possibly involving both excitatory and inhibitory systems. (nih.gov)
  • Some individuals develop dystonia (sustained muscle contractions that cause twisting of the body and limbs, repetitive movements, and distorted postures) or symptoms similar to those of Parkinson's disease, such as slowness of movement and muscle stiffness (rigidity). (nih.gov)
  • Dystonia is combined with another movement disorder (e.g., myoclonus, parkinsonism) (see Table 3 ). (nih.gov)
  • Objective tinnitus associated with essential palatal myoclonus: report in a child. (gdrvertige.com)
  • Myoclonus is a brief, involuntary, irregular (lacking rhythm) twitching of a muscle, a joint, or a group of muscles, different from clonus, which is rhythmic or regular. (wikipedia.org)
  • In this type of myoclonus, jerks usually involve only a few muscles in one part of the body, but jerks involving many muscles may occur. (wikipedia.org)
  • Additional symptoms may include peripheral neuropathy, tremor, muscle wasting (atrophy), and brief, unplanned twitching of a muscle or group of muscles (myoclonus). (nih.gov)
  • Progressive myoclonus epilepsy (PME) is a group of diseases characterized by myoclonus, epileptic seizures, tonic-clonic seizures, and other serious symptoms such as trouble walking or speaking. (wikipedia.org)
  • Myoclonus has different clinical and neurophysiological features in patients with Unverricht-Lundborg (ULD) and Lafora body disease (LBD), probably because of a different cortical hyperexcitability profile. (nih.gov)
  • Distorted own body representations in patients with dizziness and during caloric vestibular stimulation. (gdrvertige.com)
  • Rarely, people with CLN3 disease develop a distorted view of reality (psychosis) or false perceptions (hallucinations). (nih.gov)