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  • dopamine
  • The loop has also been divided into limbic, associative, oculomotor, and motor circuits to explain the role of dopamine in the basal ganglia on motivational states. (wikipedia.org)
  • History of either rheumatic fever or chorea is suspected: the suggestion is that estrogens and progesterone may sensitize dopamine receptors (presumably at a striatal level) and induce chorea in individuals who are vulnerable to this complication by virtue of preexisting pathology in the basal ganglia. (wikipedia.org)
  • It is one of the four major dopamine pathways in the brain, and is particularly involved in the production of movement, as part of a system called the basal ganglia motor loop. (wikipedia.org)
  • The substantia nigra is the source of the striatal input of the neurotransmitter dopamine, which plays an important role in basal ganglia function. (wikipedia.org)
  • antibodies
  • A patient developed this chorea with no definite evidence of previous Sydenham's chorea or recent streptoccocal infections, but had anti-basal ganglia antibodies, suggesting immunological basis for the pathophysiology of this chorea. (wikipedia.org)
  • The proposed link between infection and these disorders is that an initial autoimmune reaction to a GABHS infection produces antibodies that interfere with basal ganglia function, causing symptom exacerbations. (wikipedia.org)
  • olfactory
  • Many consider the retina and the optic nerve (2nd cranial nerve), as well as the olfactory nerves (1st) and olfactory epithelium as parts of the CNS, synapsing directly on brain tissue without intermediate ganglia. (wikipedia.org)
  • place
  • The "behavior switching" that takes place within the basal ganglia is influenced by signals from many parts of the brain, including the prefrontal cortex, which plays a key role in executive functions. (wikipedia.org)
  • loop
  • The loop was originally proposed as a part of a model of the basal ganglia called the parallel processing model, which has been criticized and modified into another model called the center surround model. (wikipedia.org)
  • studies
  • However, the timing of basal ganglia activity and limb moment, as well as lesion studies do not support this hypothesis Two models have been proposed to explain how actions are selected in the basal ganglia. (wikipedia.org)
  • several
  • Popular theories implicate the basal ganglia primarily in action selection - in helping to decide which of several possible behaviors to execute at any given time. (wikipedia.org)