• synthesis of coagulation factors
  • Anticoagulants: Warfarin Overdose: Used as a treatment for prevention of blood clots, however, like most drugs, side effects have been shown to increase risk of excessive bleeding by functioning in the disruption of hepatic synthesis of coagulation factors II, VII, IX, and X. Vitamin K is an antagonist to warfarin drug, reversing its activity, causing it to be less effective in the process of blood clotting. (wikipedia.org)
  • prothrombin
  • The mechanism specific to prothrombin (factor II) includes the proteolytically cleaving, breakdown of proteins into smaller polypeptides or amino acids, of this coagulation factor in order to form thrombin at the beginning of the cascade, leading to stemming of blood loss. (wikipedia.org)
  • studies
  • Examinations including detailed coagulation studies were performed on 30 selected patients and 14 showed characteristic signs of DIC. (jimmunol.org)