• symptoms
  • Extra material from chromosome 13 disrupts the course of normal development, causing the characteristic signs and symptoms of trisomy 13. (wikipedia.org)
  • Since some these symptoms are life-threatening, many infants born with this disorder will die within the first days to weeks of life and only 5 to 10 percent will live to celebrate their first birthday. (brighthub.com)
  • Symptoms of the disorder are comparable to those of trisomy 9p. (wikipedia.org)
  • The severity of the symptoms is largely determined by the size of the isochromosome, the specific regions of chromosome 9p that are duplicated, as well as the number and type of tissues that are affected in the mosaic form. (wikipedia.org)
  • This provides evidence that it is the number of RAI1 copies present that affects the symptoms of PTLS and SMS. (wikipedia.org)
  • developmental
  • Typical characteristics of an individual born with trisomy 18 are heart defects, kidney problems, rocker bottom feet, the intestinal tract outside of the stomach (omphalocele), an umbilical hernia, small head (microcephaly), pocket of fluid on the brain and severe developmental delays. (brighthub.com)