AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceNamed GroupsHealth CareGeographicals
Severe Acute Respiratory SyndromeSARS VirusCoronavirusSpike Glycoprotein, CoronavirusPorcine Reproductive and Respiratory SyndromeCoronavirus InfectionsPorcine respiratory and reproductive syndrome virusCoronavirus 229E, HumanNucleocapsid ProteinsCommunicable Diseases, EmergingViverridaeVero CellsViral Envelope ProteinsCercopithecus aethiopsSyndromeAntibodies, ViralCoronavirus OC43, HumanViral VaccinesMembrane GlycoproteinsDisease OutbreaksCoronaviridae InfectionsMiddle EastQuarantineHong KongVirus InternalizationPeptidyl-Dipeptidase AViral ProteinsMolecular Sequence DataMurine hepatitis virusReceptors, VirusCoronaviridaeInfectious Disease Transmission, Patient-to-ProfessionalViral Nonstructural ProteinsRNA ReplicaseVirus ReplicationNeutralization TestsCell LineViral Matrix ProteinsPatient IsolationAmino Acid SequenceRNA, ViralCoronavirus, BovineNucleocapsidSwineChiropteraArterivirusPorcine Respiratory CoronavirusCysteine EndopeptidasesPolyproteinsZoonosesCoronavirus, FelineInfection ControlCinanserinLungProtein Structure, TertiaryGenome, ViralOpen Reading FramesSingaporeVirus AttachmentEpitope MappingSaudi ArabiaCoronavirus NL63, HumanAntibodies, NeutralizingAntiviral AgentsTravelRespiratory Tract InfectionsCamelsContact TracingReverse Transcriptase Polymerase Chain ReactionAntigens, ViralVirosomesChinaPneumonia, ViralTransmissible gastroenteritis virusCarboxypeptidasesViral Structural ProteinsChronology as TopicTaiwanBase SequenceEnzyme-Linked Immunosorbent AssayCoronavirus, CanineDisease ReservoirsMice, Inbred BALB CInfectious bronchitis virusPhylogenyModels, MolecularPersonnel, HospitalArterivirus InfectionsSensitivity and SpecificitySwine DiseasesDipeptidyl Peptidase 4Cytopathogenic Effect, ViralProtein BindingRaccoon DogsArteriviridaeDisease Transmission, InfectiousRecombinant ProteinsInterferon Regulatory Factor-3MutationCrystallography, X-Ray
Pandemic2020SARS-CoV2019-nCoVDistressCenters for DiseasOutbreaksWorld Health OrganPathogenDropletsNovel coronavirus identifiedAbstractPneumoniaViralInfectionsCase of coronavirusInfluenzaEbolaMild COVID-19WuhanSeveritySymptomsIllness causedMiddle EastCovid-19Humans229EHttpsHighly infectiousAntibody21st centuryEpidemicIllnessesMortality2002VirusMutationEmerging InfectioEmergenceClinicalPathogensZikaRapidlyEpidemiologyLaboratoriesCoughAcronymVaccinesHumanDeadlyDetectionInfectious Diseases of PoveInflammatoryThreatFever
Pandemic45
  • The coronavirus disease 2019 (COVID-19) pandemic has created a global health- and economic crisis. (lu.se)
  • Since the appearance of severe acute respiratory coronavirus 2 (SARS-CoV-2) and the coronavirus disease 2019 (COVID-19) pandemic, a growing body of evidence has suggested that weather factors, particularly tem. (biomedcentral.com)
  • As an animal-origin pathogen, coronavirus can cross species barrier and cause pandemic in humans. (biomedcentral.com)
  • Considering the widespread of coronavirus disease 2019 (COVID-19) pandemic in the world, it is important to understand the spatiotemporal development of the pandemic. (biomedcentral.com)
  • Coronavirus disease 2019 (COVID-19) is a new viral disease that has caused a pandemic in the world. (biomedcentral.com)
  • The ongoing pandemic of the coronavirus disease 2019 has spread rapidly to all countries of the world. (biomedcentral.com)
  • On 11 March 2020, the World Health Organization (WHO) described the coronavirus disease 2019 (COVID-19) situation as a pandemic. (biomedcentral.com)
  • The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) and the Omicron variant presents a formidable challenge for control and preve. (biomedcentral.com)
  • COVID-19 pandemic continues, clarifying signatures in clinical characters and antibody responses between severe and non-severe COVID-19 cases would benefit the prognosis and treatment. (biomedcentral.com)
  • The ongoing coronavirus disease 2019 (COVID-19) pandemic has put a strain on health systems globally. (biomedcentral.com)
  • Early severity estimates of coronavirus disease 2019 (COVID-19) are critically needed to assess the potential impact of the ongoing pandemic in different demographic groups. (biomedcentral.com)
  • Recently, severe acute respiratory syndrome (SARS) coronavirus (CoV) 2 (SARS‑CoV‑2)‑causing CoV disease 2019 (COVID‑19) emerged in China and has become a global pandemic. (spandidos-publications.com)
  • During the Middle of December 2019, a virus-induced pneumonia emerged in Wuhan, China, which ultimately resulted in the current global pandemic ( 1 ). (spandidos-publications.com)
  • In late 2019, a new coronavirus-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-was discovered in Wuhan, China, and the World Health Organization later declared coronavirus disease 2019 (COVID-19) a pandemic. (springer.com)
  • By 11 March 2020, the World Health Organization (WHO) declared coronavirus disease 2019 (COVID-19) a pandemic and a public health emergency of international concern [ 2 ]. (springer.com)
  • The Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) pandemic has emerged as the largest global health threat to humanity in this century. (europa.eu)
  • The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic of novel corona virus disease (COVID-19). (medrxiv.org)
  • The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is the most serious health threat of this century. (europa.eu)
  • Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which was identified in late 2019 as the etiological agent of coronavirus disease 2019 (COVID-19), caused an unprecedented pandemic and global health crisis [ 1 ]. (nature.com)
  • The 2019-2020 Novel Coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2) Pandemic: A Joint American College of Academic International Medicine-World Academic Council of Emergency Medicine Multidisciplinary COVID-19 Working Group Consensus Paper. (jefferson.edu)
  • As of this article's publication date, COVID-19 has spread to approximately 200 countries and territories, with over 4.3 million infections and more than 290,000 deaths as it has escalated into a global pandemic. (jefferson.edu)
  • SC2), was first discovered in man in 2019 and declared a global pandemic by the World Health Organization on March 11, 2020. (elifesciences.org)
  • 4). Covid-19 pandemic and lack of Western altruism for the global South, including Indigenous Australians. (countercurrents.org)
  • The spread of the virus in an essentially non-immune global population was unprecedented in recent history, and by March 11, 2020, the World Health Organization had declared the outbreak of COVID-19 infection a worldwide pandemic [ 2 ]. (degruyter.com)
  • As with many newly-described diseases, especially infections, the early published literature (and we are only 8 months into this pandemic) tends to emphasize worse-case outcomes, which are more easily identified. (degruyter.com)
  • The aim of the present study was to evaluate the anxiety and depression status of lung cancer patients during the coronavirus disease 2019 (COVID‑19) pandemic and the effects of psychological counseling online. (spandidos-publications.com)
  • In the early days of the pandemic when information on COVID-19 infection was lacking, all COVID-19 positive patients were admitted into acute hospitals for. (annals.edu.sg)
  • The coronavirus disease 2019 (COVID-19) pandemic has resulted in much morbidity and mortality around the world. (annals.edu.sg)
  • The outbreak of the COVID-19 virus in 2019 had rapidly developed into a global pandemic, causing more than 6.8 million deaths and impacting the. (annals.edu.sg)
  • p class=\'abstract\'>There is a large global unmet need for the development of countermeasures to combat hundreds of viruses known to cause human disease and for the establishment of a therapeutic portfolio for future pandemic preparedness. (stanford.edu)
  • A novel coronavirus, severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2 ), causing coronavirus disease 2019 (COVID-19), entered the human population and rapidly spread around the world in the early months of 2020, causing a global pandemic. (canada.ca)
  • Coronavirus (severe acute respiratory syndrome coronavirus 2) outbreak is a public health emergency and a global pandemic. (bmj.com)
  • The global pandemic caused by severe acute respiratory syndrome coronavirus 2 has led to a significant loss of life, as well as severe disruptions to economies and social activities worldwide. (frontiersin.org)
  • The 2019-20 coronavirus pandemic resulted in some arbitrary assumptions. (barrypopik.com)
  • The technology-driven world of the 21st century is currently confronted with a major threat to humankind, represented by the coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome, coronavirus-2 (SARS-CoV-2). (unboundmedicine.com)
  • This virus, now named SARSCoV-2 due to its similarity to the severe acute respiratory syndrome coronavirus (SARS-CoV), is the cause of the current pandemic with considerable global morbidity and mortality. (health.mil)
  • Coronavirus disease 2019 (COVID-19), which is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was declared by the World Health Organization (WHO) as a global pandemic on March 11, 2020. (iasp-pain.org)
  • The emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/Coronavirus Disease 2019 (COVID-19) pandemic in the human population in November 2019 has spotlighted the importance of diagnostic testing as a (foundational) bedrock to understand how infections occur and spread. (plos.org)
  • This special issue Importantly, APSED III builds on the foundations of the highlights significant achievements across the Western earlier versions to address emerging disease threats and Pacific Region in global pandemic preparedness and public health emergencies ( Fig. 1 ). (who.int)
  • The World Health Organization (WHO) Western Pa- tious diseases, events and public health emergencies, cific Region is a hotspot for significant emerging infectious including the next influenza pandemic ( Fig. 2 ). (who.int)
  • At the end of this year's World Health Organization (WHO) list of pathogens that could cause a worldwide pandemic is a mysterious addition: "Disease X. (medscape.com)
  • Cite this: WHO Adds 'Disease X' to List of Potential Pandemic Killers - Medscape - Mar 12, 2018. (medscape.com)
  • By January 2020, severe acute respiratory syndrome coronavirus-2 has spread internationally to a pandemic that mainly targets the respiratory system. (bvsalud.org)
  • The relevant infectious disease has been identified as coronavirus disease-2019 (COVID-19) by World Health Organization and declared as a global pandemic. (bvsalud.org)
  • The level and variability of transmission during this first year of pandemic suggest that the disease in the State of Paraná was never under control. (bvsalud.org)
202014
  • Laboratory readiness and response for novel coronavirus (2019-nCoV) in expert laboratories in 30 EU/EEA countries, January 2020. (cdc.gov)
  • Since December 2019, there had been a series of unexplained cases of pneumonia reported in Wuhan, China, and on 12 January 2020, the World Health Organization (WHO) named this new virus as the 2019 novel coronavirus (2019-nCoV) (3). (who.int)
  • The novel coronavirus, named "SARS-CoV-2", was identified on 7 January 2020 by Chinese scientists. (biomedcentral.com)
  • On January 30, 2020, the WHO declared the COVID-19 outbreak a global health emergency. (medscape.com)
  • [ 5 , 6 ] On February 11, 2020, the Coronavirus Study Group of the International Committee on Taxonomy of Viruses issued a statement announcing an official designation for the novel virus: severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). (medscape.com)
  • In early January 2020, the specific virus was isolated and later identified as a novel coronavirus by sequencing ( 3 ). (spandidos-publications.com)
  • According to the World Health Organisation Situation Report of March 28th 2020, 571,659 patients were diagnosed with Coronavirus Disease 2019 (COVID-19) and 26,493 deaths were reported globally. (europa.eu)
  • The 2019-2020 Novel Coronavirus (Severe Acute Respiratory Syndrome Cor" by Stanislaw P. Stawicki, Rebecca Jeanmonod et al. (jefferson.edu)
  • This article is the authors' final published version in Journal of Global Infectious Diseases, Volume 12, Issue 2, May 2020, Pages 47-93. (jefferson.edu)
  • The disease caused by SC2 was initially noted to manifest as a pneumonia ( Lake, 2020 ). (elifesciences.org)
  • Global avoidable mortality since 1950" (2007) and "US-imposed, post-9-11 Muslim Holocaust and Muslim Genocide" (in press, 2020). (countercurrents.org)
  • The U.S. Secretary of Health and Human Services declared a public health emergency in the U.S. on 31 Jan. 2020 in response to the spread of coronavirus disease 2019 (COVID-19). (health.mil)
  • These efforts were facilitated by guidance from the Food and Drug Administration (FDA) on February 29, 2020, "Policy for Coronavirus Disease-2019 Tests During the Public Health Emergency" [ 2 ], and an Executive Order (March 12, 2020) from California State Governor Gavin Newsom modifying certain California-specific regulatory personnel requirements [ 3 ]. (plos.org)
  • In Libya, National Center for Disease Control reported the first case of coronavirus disease-2019 on 24th March, 2020. (bvsalud.org)
SARS-CoV42
  • Coronavirus disease 2019 (COVID-19) is an illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). (medscape.com)
  • Severe acute respiratory syndrome (SARS) is a respiratory disease caused by a virus called SARS-associated coronavirus (SARS-CoV). (cdc.gov)
  • SARS-CoV is thought to be transmitted most readily by respiratory droplets (droplet spread) produced when an infected person coughs or sneezes. (cdc.gov)
  • SARS-CoV-2 is a coronavirus belongs to the β-coronavirus cluster, it is the third zoonotic coronavirus disease after SARS and the Middle East respiratory syndrome (MERS) (4). (who.int)
  • Severe Acute Respiratory Syndrome (SARS) was a global disease outbreak in 2003 that was caused by a coronavirus called SARS-associated coronavirus (SARS-CoV). (cdc.gov)
  • Monocyte-derived macrophages (MDM) drive the inflammatory response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and they are a major source of eicosanoids in airway inflammation. (nature.com)
  • Here we report that MDM from SARS-CoV-2-infected individuals with mild disease show an inflammatory transcriptional and metabolic imprint that lasts for at least 5 months after SARS-CoV-2 infection. (nature.com)
  • Severe COVID-19 is associated with profound changes in the myeloid compartment, including expansion of dysfunctional, pro-inflammatory monocytes during the first weeks after SARS-CoV-2 infection 6 , 7 . (nature.com)
  • Serum and airway prostanoid- and LT levels are increased in severe COVID-19 10 , 11 , suggesting a role for eicosanoids in the immune response to SARS-CoV-2 infection. (nature.com)
  • By studying transcriptome- and lipid mediator profiles in MDM of convalescent SARS-CoV-2-infected individuals with previous mild disease, we show that inflammatory gene expression and eicosanoid profiles as well as altered responsiveness to inflammatory cues are maintained at 3-5 months post infection as well as throughout macrophage differentiation. (nature.com)
  • however potential immune aberrations in the majority of SARS-CoV-2-infected patients, affected by mild disease, have remained obscure. (nature.com)
  • Detection of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19 by serological methods is important to diagnose a current or resolved infection. (lu.se)
  • SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is the etiological agent responsible for the global COVID-19 (coronavirus disease 2019) outbreak. (rcsb.org)
  • However, the origins and global transmission pattern of SARS-CoV-2 remain lar. (biomedcentral.com)
  • Illness caused by SARS-CoV-2 was termed COVID-19 by the WHO, the acronym derived from "coronavirus disease 2019. (medscape.com)
  • The peak viral load of SARS‑CoV‑2 is estimated to occur ~10 days following fever onset, causing patients in the acute stage to be the primary infection source. (spandidos-publications.com)
  • The virus was first officially named the 2019 novel coronavirus (nCoV) by the World Health Organization (WHO) and subsequently termed 'severe acute respiratory syndrome CoV 2 (SARS-CoV-2)' by The International Committee on Nomenclature of Viruses. (spandidos-publications.com)
  • Collectively, all the associated diseases caused by SARS-CoV-2 are termed Coronavirus Disease of 2019 (COVID-19). (spandidos-publications.com)
  • As an accurate profile of the virus is urgently required, the present article screened the available literature on SARS-CoV-2 and other members of the coronavirus family to perform a literature review. (spandidos-publications.com)
  • There is currently a global outbreak of respiratory disease caused by a novel coronavirus that has been named "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2). (fda.gov)
  • Primarily, this virus was known as Severe Acute Respiratory Syndrome Coronavirus-2 (Sars-Cov-2), which initially came out in Wuhan city of China. (hindawi.com)
  • The authors concluded that men and women had a similar incidence of the diseases, but that men with COVID-19 or SARS-CoV-1 infection were at higher risk of worse outcomes and death, independent of age [ 6 ]. (springer.com)
  • Die Pandemie des Schweren akuten Atemwegssyndroms durch Coronavirus 2 (SARS-CoV-2) ist die ernsthafteste Gesundheitsbedrohung dieses Jahrhunderts. (europa.eu)
  • To achieve this, a collection of repurposed drugs, focused libraries and small molecule libraries will be screened against SARS-CoV-2, other emerging SARS-CoV-2 clades and related coronavirus genera in phenotypic or target-based assays. (europa.eu)
  • These findings suggest that a high infection rate by SARS-CoV-2 may lead to exaggerated cytokine responses, which may contribute to tissue damage and severe disease. (nature.com)
  • The pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel Betacoronavirus , was subsequently isolated as the causative agent. (jefferson.edu)
  • Pregnant women may be at risk for more severe manifestations and sequelae of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). (degruyter.com)
  • Coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first described in China in December 2019 [ 1 ]. (degruyter.com)
  • Patients with lung cancer are more likely to develop severe adverse conditions following infection with SARS-CoV-2 due to low immunity and the presence of lung lesions. (spandidos-publications.com)
  • Are higher antibody levels against seasonal human coronaviruses associated with a more robust humoral immune response after SARS-CoV-2 vaccination? (frontiersin.org)
  • The SARS-CoV-2 belongs to the coronavirus family, which also includes common endemic coronaviruses (HCoVs). (frontiersin.org)
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a betacoronavirus in the sarbecovirus family, has caused significant global morbidity and mortality. (frontiersin.org)
  • Vaccines have been introduced which generate robust immune responses against SARS-CoV-2 and also provide effective protection particularly against the development of severe disease ( 1 , 2 ). (frontiersin.org)
  • A vaccine (or vaccines) against SARS-CoV-2 would help develop community immunity against the virus and thus prevent the spread and recurrence of the disease at the population level. (canada.ca)
  • We aimed to evaluate the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and adverse pregnancy outcomes. (cmaj.ca)
  • We searched for eligible studies in MEDLINE, Embase, ClinicalTrials.gov , medRxiv and Cochrane databases up to Jan. 29, 2021, using Medical Subject Headings terms and keywords for "severe acute respiratory syndrome coronavirus 2 OR SARS-CoV-2 OR coronavirus disease 2019 OR COVID-19" AND "pregnancy. (cmaj.ca)
  • SARS-CoV-2 spreads much faster than its two ancestors, SARS-CoV and Middle East respiratory syndrome-CoV (MERS-CoV), but has low fatality rates. (unboundmedicine.com)
  • Women and children are less susceptible to SARS-CoV-2 infection, while the elderly and people with comorbidities are more prone to serious clinical outcomes, which may be associated with acute respiratory distress syndrome (ARDS) and cytokine storm. (unboundmedicine.com)
  • 1-5 Genomic analysis revealed that SARS-CoV-2 is phylogenetically related to severe acute respiratory syndrome-like (SARS-like) bat viruses, suggesting that bats could be the possible primary reservoir. (health.mil)
  • This review offers an overview of the various types of coronaviruses (CoVs), their targeted hosts and cellular receptors, a timeline of their emergence, and the roles of key elements of the immune system in fighting pathogen attacks, while focusing on SARS-CoV-2 and its genomic structure and pathogenesis. (iasp-pain.org)
  • Introduction: Hospitalised patients with coronavirus disease 2019 (COVID-19) as a result of SARS-CoV-2 infection have a high mortality rate and frequently require noninvasive respiratory support or invasive ventilation. (bvsalud.org)
  • Severe acute respiratory syndrome (SARS) is a serious, potentially life-threatening viral infection caused by a previously unrecognized virus from the Coronaviridae family, the SARS-associated coronavirus (SARS-CoV). (medscape.com)
2019-nCoV7
  • Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. (cdc.gov)
  • The 2019 Novel Coronavirus, termed "2019-nCoV" for short, is a type of coronavirus responsible for causing respiratory distress in the infected. (appleinsider.com)
  • SARS, MERS, and now 2019-nCoV are global outbreaks. (appleinsider.com)
  • Many of the deaths in the 2019-nCoV outbreak have been those who already had pre-existing conditions that would have made fighting the virus much more difficult, including diabetes, high blood pressure, and heart disease. (appleinsider.com)
  • Experts are not sure how the virus spreads from person to person, 2019-nCoV is thought to spread like most other respiratory illnesses - from contact with saliva and mucus. (appleinsider.com)
  • formerly called 2019-nCoV), which was first identified amid an outbreak of respiratory illness cases in Wuhan City, Hubei Province, China. (medscape.com)
  • In addition, they per- virus as the 2019 novel coronavirus (2019-nCoV) ( 3 ). (who.int)
Distress4
  • The virus primarily infects the respiratory tract, resulting in pneumonia, acute respiratory distress syndrome (ARDS) and other fatal complications, including acute kidney injury, coagulation dysfunction and shock, according to a published report ( 4 ). (spandidos-publications.com)
  • In most critical cases, symptoms can escalate into acute respiratory distress syndrome accompanied by a runaway inflammatory cytokine response and multiorgan failure. (jefferson.edu)
  • Coronavirus disease of 2019 (COVID-19) infection will progress to acute respiratory distress syndrome in approximately 15-30% of hospitalized patients ( 1 ). (frontiersin.org)
  • These symptoms vary from person to person, ranging from mild to hypoxia with acute respiratory distress syndrome (ARDS) and sometimes death. (iasp-pain.org)
Centers for Diseas7
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • Whereas children comprise slightly over 22% of the US population, 17.2% of all cases of COVID-19 reported to the Centers for Disease Control and Prevention (CDC) were among children (as of January 11, 2023). (medscape.com)
  • According to the Centers for Disease Control and Prevention (CDC), a virucide is "An agent that kills viruses to make them noninfective. (wikipedia.org)
  • The U.S. Centers for Disease Control and Prevention administers a regulatory framework for disinfectants and sterilants. (wikipedia.org)
  • Announcer] This program is presented by the Centers for Disease Control and Prevention. (cdc.gov)
  • Canada, more specifically Toronto, Ontario (yellow), is the fifth-ranked area, although community transmission of SARS now appears to be contained, according to the US Centers for Disease Control and Prevention. (medscape.com)
Outbreaks7
  • Scientists find out COVID-19 to be one of the crucial outbreaks that attack the respiratory system [ 1 ]. (hindawi.com)
  • The regulations outline the minimum requirements for functional public health system that allows countries to quickly detect and respond to disease outbreaks in their communities. (cdc.gov)
  • But a pattern in which outbreaks are driven by relatively few cases holds across several diseases, including HIV, tuberculosis and typhoid, according to researchers who study disease patterns. (ijpr.org)
  • Furthermore, it is impossible to predict the characteristics of these viruses, the severity of the diseases they might induce and the scope of the outbreaks they can cause. (canada.ca)
  • In recent years, the collection of genomic sequences of the coronavirus that causes Severe Acute Respiratory syndrome (SARS) and various strains of the influenza A virus have become an vital part of fighting outbreaks of these infectious diseases. (scienceblog.com)
  • Accurate diagnostic testing is at the center of controlling infectious disease outbreaks. (plos.org)
  • Thus, broad testing capability is necessary to quell resurgence of outbreaks and reopen the global economy. (plos.org)
World Health Organ1
  • the WHO (World Health Organization) warned that if control measures are not implemented in time, then the outbreak of the coronavirus can spread more rapidly [ 2 ]. (hindawi.com)
Pathogen3
  • If the movement of a pathogen is related to bird flyways, and those routes are shifting because of something like climate change, we can predict where the disease might logically emerge next. (scienceblog.com)
  • The initial jump of a pathogen into humans has become increasingly important to understand because of growing human-animal contact and global travel. (scienceblog.com)
  • Disease X represents the knowledge that a serious international epidemic could be caused by a pathogen currently unknown to cause human disease," the WHO explains on its website. (medscape.com)
Droplets1
  • The virus is mainly transmitted via respiratory droplets and human contact of contact with contaminated surfaces ( 4 , 5 ). (spandidos-publications.com)
Novel coronavirus identified1
Abstract1
  • Abstract Since 2019, the coronavirus disease-19 (COVID-19) has been spreading rapidly worldwide, posing an unignorable threat to the global economy and human health. (techscience.com)
Pneumonia4
  • This work was supported by grants from the National Natural Science Fund for Distinguished Young Scholars (No. 31825011 to L.Y.) and the Chongqing Special Research Project for Novel Coronavirus Pneumonia Prevention and Control (No. cstc2020jscx-2 to L.Y. (medrxiv.org)
  • The symptoms of COVID-19 include cough, fever, diarrhea, shortness of breath and severe pneumonia ( 6 , 7 ). (spandidos-publications.com)
  • A novel (new) coronavirus was identified as the cause of a cluster of pneumonia cases in Wuhan, a city in the Hubei province of China, in Dec. 2019. (health.mil)
  • Coronaviruses are enveloped RNA viruses that cause respiratory illnesses of varying severity from the common cold to fatal pneumonia. (msdmanuals.com)
Viral8
  • Emerging viral infections are among the major global public health concerns. (hindawi.com)
  • This review article aims to review the ethnobotanical knowledge of medicinal plants traditionally used to treat different viral diseases by the Ethiopian people and suggests those plants as candidates to fight COVID-19. (hindawi.com)
  • Viral diseases are responsible for the global morbidity and mortality of human beings [ 1 ]. (hindawi.com)
  • However, no specific medications and drugs are known to treat this viral disease. (hindawi.com)
  • The CDC advised that nonpharmaceutical interventions (NPIs) are the most important response strategy for delaying viral spread and reducing disease impact. (medscape.com)
  • Evaluation of SC2 strains demonstrated impressive genetic variability, and many of these viral variants are now defined as variants of concern (VOC) that cause enhanced transmissibility, decreased susceptibility to antibody neutralization or therapeutics, and/or the ability to induce severe disease. (elifesciences.org)
  • In the past few decades, there has been rapid spread of numerous severe viral infections, including human immunodeficiency virus (HIV), influenza A, severe acute respiratory syndrome (SARS), Ebola and Zika. (canada.ca)
  • Common Cold The common cold is an acute, usually afebrile, self-limited viral infection causing upper respiratory symptoms, such as rhinorrhea, cough, and sore throat. (msdmanuals.com)
Infections5
  • Mathematical models are quite helpful in investigating the behavior of viruses, diseases, or infections and help out to conclude under what circumstances the outbreaking virus can be eradicated or continued in citizens and are often useful in estimating the duration of an outbreak. (hindawi.com)
  • In diseases driven by super-spreading, a rule of thumb is the " 20/80 rule " - around 20% of individuals are responsible for at least 80% of the infections, though the actual numbers vary by disease, Metcalf says. (ijpr.org)
  • Lead researcher Sarah Warnes said: 'Transmission of infectious diseases via contaminated surfaces is far more important than was originally thought, and this includes viruses that cause respiratory infections. (cityam.com)
  • disease events, including human infections with avian influenza viruses. (who.int)
  • These coronaviruses that cause severe respiratory infections are zoonotic pathogens, which begin in infected animals and are transmitted from animals to people. (msdmanuals.com)
Case of coronavirus1
Influenza4
  • A voluntary network of laboratories that submit test data to the CDC will provide valuable information as another early indicator of spread, along with other respiratory diseases (eg, influenza, RSV). (medscape.com)
  • There is also a list of four diseases that always need to be reported to WHO: severe acute respiratory syndrome or SARS, smallpox, new influenza viruses, and wild-type polio. (cdc.gov)
  • ICAR-National Institute of High Security Animal Diseases, OIE Reference Laboratory for Avian Influenza, Bhopal, Madhya Pradesh 462 022, India. (unboundmedicine.com)
  • For more than a decade, the Asia Pacific Strategy influenza viruses have occurred every 10-40 years, with for Emerging Diseases and Public Health Emergencies each of the pandemics in 1957, 1968 and 1977 taking (APSED III) and its earlier versions in 2005 and 2010 the lives of roughly one million people. (who.int)
Ebola3
  • The world's scientific community is focused on how to improve detection and responses to emerging diseases such as Zika virus and Ebola. (medicaldaily.com)
  • These days, we seem to see more "new" diseases, such as Zika, Ebola and SARS. (medicaldaily.com)
  • A popular healer treated Ebola patients from an outbreak in neighboring Guinea, contracted the disease and died. (ijpr.org)
Mild COVID-192
  • Early and strong interferon type I (IFN-I) responses are usually associated with mild COVID-19 disease, whereas persistent or unregulated proinflammatory cytokine responses are associated with severe disease outcomes. (nature.com)
  • Compared with mild COVID-19, severe COVID-19 was strongly associated with preeclampsia (OR 4.16, 95% CI 1.55 to 11.15), preterm birth (OR 4.29, 95% CI 2.41 to 7.63), gestational diabetes (OR 1.99, 95% CI 1.09 to 3.64) and low birth weight (OR 1.89, 95% CI 1.14 to 3.12). (cmaj.ca)
Wuhan3
  • The city of Wuhan, China has begun enforcing strict rules aimed at minimizing the spread of the new disease, which has claimed 80 lives before January 27 according to the Chinese government. (appleinsider.com)
  • What started as a cluster of patients with a mysterious respiratory illness in Wuhan, China, in December 2019, was later determined to be coronavirus disease 2019 (COVID-19). (jefferson.edu)
  • 3. Specimen collection and shipment in Wuhan, China (See: Surveillance case definitions for Rapid collection and testing of appropriate specimens from human infection with novel coronavirus, Interim guidance). (who.int)
Severity2
  • In this regard, mathematical and data-driven modelling studies may help provide evidence and insights into the transmission, severity, and particularity of the disease, which could readily inform decision-making in combating the disease. (biomedcentral.com)
  • The wide spectrum of clinical symptoms, disease severity in high risk individuals, transmission efficiency and high mortality, raises an immediate need for vaccines or therapeutics. (europa.eu)
Symptoms4
  • All airline personnel, especially those who have been exposed to a person who might have SARS, should be aware of the symptoms of the disease . (cdc.gov)
  • Those who have the disease are contagious for a few days before they show symptoms, and those who become infected may not show symptoms until 14 days after exposure. (appleinsider.com)
  • Long-term symptoms of COVID-19 are common after severe disease 2 , but may also affect 15-20% of individuals with previous mild disease 3 . (nature.com)
  • The case fatality rate of COVID-19 is debated but appears to be lower than Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS), with an estimated 5% of those experiencing symptoms requiring hospitalisation. (bvsalud.org)
Illness caused1
Middle East4
Covid-1922
  • Dosage regimens are available for those requiring hospitalization, or are not hospitalized and have mild-to-moderate COVID-19 and are at high risk for progression to severe COVID-19. (medscape.com)
  • Our study provides a comprehensive validation of the rapid COVID-19 IgM/IgG serology test, and mapped antibody detection patterns in association with disease progress and hospitalization. (lu.se)
  • The disease caused by the virus has been named "Coronavirus Disease 2019" (COVID-19). (fda.gov)
  • Methylene Blue works by producing a hydrogen peroxide burst within the blood to kill the Coronavirus (COVID-19) on contact. (fda.gov)
  • At present, emergence of deadly respiratory virus COVID-19 throughout 209 countries of the world is a major global concern. (hindawi.com)
  • One of the main reasons behind the outspread of COVID-19 is due to the transmission of germs through respiratory globules among humans, and this virus is considered to be the vector transmission. (hindawi.com)
  • Researchers are adopting different tactics to investigate the growing behavior of the coronavirus and carrying out their studies to find out the ways to bring COVID-19 to an end. (hindawi.com)
  • We extracted reports on COVID-19-specific treatments from the global ADR database, VigiBase, using an algorithm developed to identify reports that listed COVID-19 as the indication. (springer.com)
  • Review of a global database of suspected ADR reports revealed sex differences in the reporting patterns for drugs used in the treatment of COVID-19. (springer.com)
  • Sex differences in the reporting of adverse drug reactions (ADRs) for COVID-19-related drugs were observed in a global ADR database. (springer.com)
  • As there were initially no authorized treatments for COVID-19, any drug used in the treatment of the disease could be considered off-label use. (springer.com)
  • In fact, in patients suffering from severe COVID-19, massive infiltration of proinflammatory immune cells, including activated macrophages, was detected in infected lung tissue. (nature.com)
  • My Submission largely took the form of succinct summaries of a series of Covid-19-related articles I had published (6 in Countercurrents, 1 in Global Research and 1 with Professor Richard Hil in the respected Australian intellectual journal Arena). (countercurrents.org)
  • Despite the limitations of the data set, this report suggested that pregnant patients should be counseled on theoretically higher risks associated with disease, while they should continue following general recommendations for infection control for the prevention of COVID-19 [ 29 ]. (degruyter.com)
  • With the increase in the number of confirmed COVID-19 diagnoses, the difficulty of diagnosis due to the lack of global healthcare resources becomes increasingly apparent. (techscience.com)
  • During the present coronavirus disease (COVID-19) crisis, telemedicine has been recommended to screen suspected patients to limit risk of exposure and maximise medical staff protection. (bmj.com)
  • The impact of coronavirus disease 2019 (COVID-19) on maternal and newborn health is unclear. (cmaj.ca)
  • The rare and severe adverse effects associated with coronavirus disease of 2019 (COVID-19) vaccination have been under-appreciated, resulting in many instances of inappropriate management. (frontiersin.org)
  • We describe the case of an elderly woman who developed anti-neutrophil cytoplasmic antibody-associated vasculitis with pulmonary renal syndrome approximately 3 weeks after the first dose of COVID-19 mRNA vaccination (Moderna). (frontiersin.org)
  • The early examination of urinalysis and renal function may be crucial for identifying glomerulonephritis and acute renal failure in susceptible patients after COVID-19 vaccination. (frontiersin.org)
  • An increasing number of studies has also supported a possible link between COVID-19 vaccination and the rapid development of de novo or relapsed glomerular diseases, such as anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV). (frontiersin.org)
  • By late 2019, China notified a new disease rising, and with the agent's identification, it was called COVID-19. (bvsalud.org)
Humans4
  • Like most coronaviruses, it's thought that the virus mutated from a strain that only infected animals, to one capable of infecting humans. (appleinsider.com)
  • Humans have been "acquiring" infectious diseases from animals (zoonotic diseases) since we first started hunting wild game on the African savannahs. (medicaldaily.com)
  • Early on, we didn't know that the illness was caused by a coronavirus or that it had likely jumped from animals to humans. (cdc.gov)
  • Only 7 coronaviruses are known to cause disease in humans. (msdmanuals.com)
229E2
  • When they placed coronavirus 229E on a surface containing copper, they found that the virus was destroyed within minutes, and the implications of this are huge - the majority of man-made surfaces, such as glass and rubber, allow coronavirus to survive for many days on end without any human contact. (cityam.com)
  • Coronaviruses 229E, OC43, NL63, and HKU1 cause about 15 to 30% of cases of the common cold. (msdmanuals.com)
Https1
  • 2. Serum for serological testing, acute sample and (https://www.gisaid.org/) and can inform the development of convalescent sample (this is additional to specific diagnostic tests for this emergent coronavirus. (who.int)
Highly infectious1
  • Caused by a highly infectious coronavirus , it was a global shock which demonstrated how quickly diseases can spread around the world. (medicaldaily.com)
Antibody2
  • Gross hematuria, heavy proteinuria, acute renal failure (serum creatinine up to 6.5 mg/dL), and hemoptysis coupled with a marked increase in serum anti-myeloperoxidase-O antibody were observed. (frontiersin.org)
  • The panel makes a conditional recommendation for interleukin (IL)-6 receptor antagonist monoclonal antibody treatment and high-flow nasal oxygen or continuous positive airway pressure in patients with hypoxaemic respiratory failure. (bvsalud.org)
21st century1
Epidemic2
  • CDC laboratories sequenced the genome for the coronavirus believed to be responsible for the global epidemic of severe acute respiratory syndrome ( SARS ). (cdc.gov)
  • Each year, the WHO identifies diseases for which there are no or insufficient countermeasures and that pose a public health risk because of their potential for causing an epidemic. (medscape.com)
Illnesses1
  • As with most respiratory illnesses, those at greatest risk are children under three and adults over 65. (appleinsider.com)
Mortality4
  • While the majority of individuals suffer from mild respiratory disease, some patients develop life-threatening inflammatory multiorgan disease that is associated with high morbidity and mortality rates. (nature.com)
  • I have written extensively (in books, chapters of books, print journals and electronic journals) about avoidable mass mortality associated with famine, disease, war and occupation, notably in 2 further large books "Body Count. (countercurrents.org)
  • In addition, lung cancer has the characteristics of a high mortality rate and thus, regular reviewing of the disease and treatment updates are required. (spandidos-publications.com)
  • Congenital heart diseases (CHDs) are the most common major congenital anomaly at up to 28%1 and are responsible for 5.7% of all infant mortality.2. (annals.edu.sg)
20026
  • SARS was recognized as a global threat in March 2003, after first appearing in Southern China in November 2002. (cdc.gov)
  • An example of this is the outbreak of severe acute respiratory syndrome or SARS that started in China in 2002. (cdc.gov)
  • was identified in 2003 as the cause of an outbreak of severe acute respiratory syndrome (SARS) that began in China near the end of 2002. (msdmanuals.com)
  • Since the 2002-2003 outbreak of SARS, which initially began in the Guangdong province of southern China but eventually involved more than 8000 persons worldwide (see the image below), global efforts have virtually eradicated SARS as a threat. (medscape.com)
  • World map of severe acute respiratory syndrome (SARS) distribution from the 2002-2003 outbreak infection. (medscape.com)
  • Since the 2002-2003 outbreak of SARS, which apparently began in southern China but eventually involved more than 8000 persons worldwide (see the image below), global efforts have virtually eradicated SARS as a threat. (medscape.com)
Virus11
  • Zika virus is the latest emerging disease to hit the news. (medicaldaily.com)
  • Infection with this virus can cause illness, ranging from common cold to more severely, respiratory diseases, like SARS and MERS. (biomedcentral.com)
  • The themes covered in this series include but are not limited to epidemiological survey and data management, transmission mechanism and modeling, virus biology and sequencing analysis, disease treatment and control measures, etc. (biomedcentral.com)
  • In the first few days of its emergence, this disease was simply identified as a virus-related respiratory disease. (spandidos-publications.com)
  • Therefore, knowledge on the molecular characteristics and host immunity in reaction to the virus would aid physicians to further understand the disease, manage patients and implement the occupational precautions. (spandidos-publications.com)
  • That's significantly more than the current global death toll from the virus itself. (dailymail.co.uk)
  • Until now, almost 13 vaccinations against this disease exist and scientists are still devoting their attentions to produce a strong vaccination against this virus. (hindawi.com)
  • In general, global population was susceptible to this virus. (spandidos-publications.com)
  • It is a disease caused by severe acute respiratory syndrome coronavirus 2, a single-stranded RNA virus of the genus Betacoronavirus. (techscience.com)
  • In addition, many of these viruses represent zoonoses (zoonotic diseases), increasing the risk of introducing a virus with completely new immunogenic properties into the human population. (canada.ca)
  • Attempts to culture the virus with a characteristic crown morphology: a coronavirus. (who.int)
Mutation1
  • Possible sources of such a disease include a mutation of a known disease, a disease arising through a human-animal interaction, or an act of terror. (medscape.com)
Emerging Infectio1
  • Our conversation is based on her study about Public Health Events and International Health Regulations, which appears in CDC's journal, Emerging Infectious Diseases. (cdc.gov)
Emergence2
  • This application integrates genetic sequences of pathogens with geographic information so that researchers can track the spread of a disease among different hosts and follow the emergence of key mutations across time and space. (scienceblog.com)
  • We aim for our tools to inform decisions about potential global hotspots for the emergence of diseases from animals and areas of drug resistance. (scienceblog.com)
Clinical2
  • Numerous drugs have been repurposed and investigated for therapeutic effectiveness in the disease, including those from "Solidarity," an international clinical trial (azithromycin, chloroquine, hydroxychloroquine, the fixed combination lopinavir/ritonavir, and remdesivir). (springer.com)
  • However, the cellular and molecular events that account for the multiple waves of disease and the impressive clinical and pathological heterogeneity that have been seen have not been defined. (elifesciences.org)
Pathogens2
  • Pathogens can now be easily tracked in time and space as they evolve, an advance that could revolutionize both public health and inform national security in the fight against infectious diseases. (scienceblog.com)
  • Another recent use of genetics, geography, and the phylogenetic trees that map the evolutionary relationships among different strains of pathogens is to predict hotspots of disease reemergence. (scienceblog.com)
Zika1
  • The human disease caused by Zika had remained largely invisible since its first identification in 1954. (medicaldaily.com)
Rapidly3
  • In order to rapidly share scientific evidence and experiences acquired in studies regarding above strategies within the international communities, Infectious Diseases of Poverty has launched this series. (biomedcentral.com)
  • Antimicrobial copper" could soon become a common term in the medical world - researchers from the University of Southampton have discovered that the metal can rapidly inactivate certain viruses, stopping them from spreading and causing disease. (cityam.com)
  • Human coronavirus, which also has ancestral links with bat-like viruses responsible for Sars and Mers, was found to be permanently and rapidly deactivated upon contact with copper. (cityam.com)
Epidemiology1
  • 4 Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. (nih.gov)
Laboratories2
  • For case definition see: WHO Surveillance case definitions to laboratories and stakeholders involved in laboratory for human infection with novel coronavirus. (who.int)
  • laboratories that can perform pan coronavirus detection and A single negative test result, particularly if this is from an directed sequencing. (who.int)
Cough2
  • Known preventive measures such as respiratory hygiene, cough etiquette (covering the nose and mouth when coughing), wearing a mask, frequent hand washing, cleaning and disinfection of surfaces, social distancing, avoiding social gatherings and handshaking, and refraining from touching the face, go simultaneously with the initiative. (who.int)
  • Known preventive measures such as respiratory for ventilation, while also providing them with educa- hygiene, cough etiquette (covering the nose and mouth tional materials, and establishing fixed washing units for when coughing), wearing a mask, frequent hand soap, water and sanitizer in taxis. (who.int)
Acronym1
Vaccines3
  • To date, no prophylactic vaccines or approved therapeutic agents are available for preventing and treating this highly transmittable disease. (medrxiv.org)
  • Conventional vaccines-live attenuated or inactivated-have proved to be beneficial against a number of infectious diseases in the past. (canada.ca)
  • These include the suboptimal coverage of key antigens, the promising progress made in introducing new vaccines, and the progress made against disease elimination and eradication targets. (who.int)
Human2
  • Serological studies have documented evidence of antibodies to other human endemic coronaviruses (HCoV's), which include leading causes of the "common cold" ( 8 ). (frontiersin.org)
  • Our expertise is now being applied to a new, practical set of research questions, the spread of disease and human health. (scienceblog.com)
Deadly1
Detection2
  • The focus is on early detection and reporting to allow for a public health response before international spread occurs, or at least to minimize the global impact of an outbreak. (cdc.gov)
  • Modifiable with information on whether upper or lower disease control activities, and to work with reference respiratory material is better for coronavirus detection. (who.int)
Infectious Diseases of Pove1
Inflammatory1
  • This may to a certain degree explain why this type of CoV triggers severe inflammatory responses and immune damage and its associated complications. (spandidos-publications.com)
Threat2
  • Current state-of-science, mitigation strategies, possible therapies, ethical considerations for healthcare workers and policymakers, as well as lessons learned for this evolving global threat and the eventual return to a "new normal" are discussed in this article. (jefferson.edu)
  • With more than 30 million children under five years of age suffering from vaccine-preventable diseases (VPDs) every year in Africa, VPDs remain a major threat. (who.int)
Fever1