Diseases gastric mucosa. Medical search. Frequent questions

Gastritis is a disease characterized by inflammation of the gastric mucosa. (koreamed.org)
Gastric MALToma symptoms may mimic those of peptic ulcer disease or gastritis. (medscape.com)
When this process is disrupted by conditions like atrophic gastritis, celiac disease, small bowel resection etc, B12 deficiency ensues. (wikidoc.org)
Chronic gastritis is a common condition that occurs when an inflammatory infiltrate is present in the gastric mucosa. (ueg.eu)
Although the inflammatory infiltrate itself may not cause a disease per se, in some cases gastritis will evolve into atrophic gastritis, ulcers or gastric cancer. (ueg.eu)
Studies have indicated that H. pylori detection is associated with a variety of gastrointestinal diseases including gastritis, duodenal and gastric ulcer, non-ulcer dyspepsia, gastric adenocarcinoma and lymphoma. (rapidtest.com)
The histological evaluation of the gastric mucosa is mandatory for diagnosing and classifying gastritis. (eur.nl)
The clinical importance of gastritis lays in the fact that it predisposes to more pronounced damage to the gastric mucosa, in particular peptic ulcer disease, and eventually atrophic gastritis, intestinal metaplasia and gastric malignancy, both adenocarcinoma and MALT lymphoma. (eur.nl)
This bacterial infection (usually acquired in childhood) initially affects only the antral mucosa causing superficial gastritis. (iiarjournals.org)
Results Fifteen of 21 (71 %) H. pylori -associated gastritis patients exhibited medium-to-large atrophic mucosa at the corpus lesser curvature. (thieme-connect.com)
Conclusions IEE findings of the gastric corpus differed between H. pylori -associated and autoimmune gastritis, suggesting different pathogenesis of the two diseases. (thieme-connect.com)
Discrimination of these two types of gastritis is important to understand the risk of different diseases that may develop in patients with atrophic gastritis. (thieme-connect.com)
Chronic gastritis is the major cause of human gastric cancer caused by the Gram-negative bacterium Helicobacter pylori . (nature.com)
investigated pathogenesis and immunological response caused by HomB protein in clinical patients and 190 H. pylori strain isolated from patients with peptic ulcer disease (PUD) or gastritis were evaluated for the clinical importance of homB . (nature.com)
5 It is the major cause of gastric carcinogenesis and other gastric diseases, such as, chronic gastritis, gastroduodenal ulcers, and gastric mucosa-associated lymphoid tissue lymphoma. (biocare.net)
There is insufficient evidence to support routine testing for and treatment of H. pylori in asymptomatic individuals with a family history of gastric cancer or patients with lymphocytic gastritis, hyperplastic gastric polyps, and hyperemesis gravidarum. (guidelinecentral.com)
A GRAM-NEGATIVE, microaerophilic curved bacillus found in gastric-biopsy specimens from patients with histologie gastritis was successfully cultured in Perth, Australia, in 1982 and was soon named Campylobacter pylori 1 (a name later changed to Helicobacterpylori). (elsevierpure.com)
Little attention had been paid to previous descriptions of spiral organisms in biopsy specimens of human gastric mucosa, 2 3 but it now appears that at the least the organism is responsible for most cases of gastritis not associated with another known primary cause (e.g., autoimmune gastritis or eosinophilic gastritis) and that it may also be a major factor in the pathogenesis of peptic ulcer disease. (elsevierpure.com)
6] Risk factors for gastric cancer include the presence of precursor conditions such as chronic atrophic gastritis and intestinal metaplasia, pernicious anemia, and gastric adenomatous polyps. (cdc.gov)

In the present work, effects in the gastric mucosa of mice treated with Pteridium aquilinum were evaluated, as well as molecular mechanisms underlying the synergistic role with Helicobacter pylori infection. (pasteur.fr)
Background/Aims: Little is known about the effect of Helicobacter pylori eradication on the recurrence of gastric hyperplastic polyps after endoscopic resection. (koreamed.org)
ABSTRACT In this study, endoscopy patients with and without chronic liver disease (CLD) were examined and tested for Helicobacter pylori infection by detecting the presence of serum and salivary anti-H. pylori antibody. (who.int)
Helicobacter and gastric MALT lymphoma. (medscape.com)
Helicobacter pylori is a spiral bacterium cultured from human gastric mucosa identified by Marshall in 1982. (rapidtest.com)
Helicobacter pylori is a Gram-negative bacterium that causes chronic inflammations in the stomach area and is involved in ulcers, which can develop into gastric malignancies. (nature.com)
Hom (Helicobacter outer membrane) family of OMPs in H. pylori consists of four members (HomA, B, C and D). In the H. pylori genome jhp 0870 open-reading frame (ORF) that codes for HomB outer membrane protein is associated with many stomach diseases and is a novel co-marker for peptic ulcer disease (PUD) 9 , 10 . (nature.com)
Helicobacter pylori is a spiral-shaped, gram-negative bacterium, which colonizes the gastric epithelium. (biocare.net)
Peterson, WL 1991, ' Helicobacter pylori and peptic ulcer disease ', New England Journal of Medicine , vol. 324, no. 15, pp. 1043-1048. (elsevierpure.com)
Peterson, Walter L. / Helicobacter pylori and peptic ulcer disease . (elsevierpure.com)
6-8] There is consistent evidence that Helicobacter pylori infection, also known as H. pylori infection, of the stomach is strongly associated with both the initiation and promotion of carcinoma of the gastric body and antrum and of gastric lymphoma. (cdc.gov)

A peptic ulcer is an open sore or raw area in the lining of the stomach (gastric) or the upper part of the small intestine (duodenal). (mountsinai.org)
About 10% to 15% of people infected with H pylori develop peptic ulcer disease. (mountsinai.org)
3 The take-home message is that it is never too late to eradicate H. pylori , 2 and eradication may represent a unique opportunity for primary prevention of gastric cancer and also of peptic ulcer disease. (ueg.eu)
Peptic Ulcer Disease (PUD) is a common cause of epigastric pain. (obgproject.com)
The Hom OMP family consists of four members, of which homB is the most studied, and evaluated for its prevalence in various peptic diseases. (nature.com)
All patients with active peptic ulcer disease (PUD), a past history of PUD (unless previous cure of H. pylori infection has been documented), low-grade gastric mucosa-associated lymphoid tissue (MALT) lymphoma, or a history of endoscopic resection of early gastric cancer (EGC) should be tested for H. pylori infection. (guidelinecentral.com)

Due to the unobvious early symptoms and the influence of some adverse factors such as tumor heterogeneity and low immunogenicity, patients with advanced gastric cancer (AGC) cannot benefit significantly from treatments such as radical surgical resection, radiotherapy, chemotherapy, and targeted therapy. (frontiersin.org)
The prognosis for early disease is excellent, with a 5-year survival rate between 85% and 90% as compared with 28%-40% in advanced gastric cancer. (medscape.com)
therefore, trastuzumab in combination with chemotherapy is a treatment option for patients with HER2-positive advanced gastric cancer. (medscape.com)
Overall, Wang believes that these results validate claudin 18 as a new predictive biomarker for advanced gastric cancer, although he noted that widespread implementation for this indication may be limited, as the assay to determine claudin 18 levels is not widely available. (medscape.com)

9-11] The International Agency for Research on Cancer classifies H. pylori infection as a cause of noncardia gastric carcinoma and gastric low-grade B-cell mucosa-associated lymphoid tissue or MALT lymphoma (i.e., a Group 1 human carcinogen). (cdc.gov)

The organism is present in 95-98% of patients with duodenal ulcer and 60-90% of patients with gastric ulcers. (rapidtest.com)
The large volume of literature reporting its effectiveness indicates that honey has therapeutic features that indicate it has potential for the treatment of periodontal disease, mouth ulcers and other problems of oral health. (mizar5.com)
Honey has a potent broad-spectrum antibacterial activity that rapidly clears infection from wounds when applied topically, which may make it suitable for "anti-infective" treatment of periodontal disease as well as for clearing infection in mouth ulcers and wounds from oral surgery. (mizar5.com)
and the large volume of literature appearing on the effectiveness of honey in treating infected wounds and skin ulcers describes features that indicate that honey has potential for the therapy of periodontal disease, mouth ulcers and other problems of oral health. (mizar5.com)
Patients and controls a possible cause of gastric ulcers seen in This was a case-control study of H. pylori patients with CLD [ 10,11 ]. (who.int)

An upper gastrointestinal endoscopy can be scheduled according to diverse indications and it is crucial for the detection of gastric cancer and its precursors. (ueg.eu)
Review the evidence on the benefits and harms of screening for gastric cancer using barium-meal photofluorography, gastric endoscopy, or serum pepsinogen in this expert-reviewed summary. (oncolink.org)
When upper endoscopy is undertaken in patients with dyspepsia, gastric biopsies should be taken to evaluate for H. pylori infection. (guidelinecentral.com)

In six cases, multiple sites in the gastrointestinal tract were involved, but in five cases this appeared to be secondary to massive mesenteric or retroperitoneal lymph node disease. (nih.gov)
A thorough understanding of the cutaneous/gastrointestinal (GI) relationship can alert the astute clinician to occult disease within the GI tract. (medscape.com)
The first methods developed and used by practitioners new to laparoscopy are collection of samples for diagnosis of gastrointestinal and accessory organ disease. (vin.com)
Pathophysiology is due to discontinuation of the inner lining of the gastrointestinal (GI) tract due to gastric acid secretion or pepsin causing an ulcer. (obgproject.com)
Polygonum hydropiper L is extensively used as a traditional Chinese herbal medicine for treating gastrointestinal diseases in China, the reports shows that it possess various pharmacological activities, especially antioxidant and anti-inflammatory properties. (uwi.edu)

Early disease is defined as adenocarcinoma limited to the gastric mucosa and submucosa regardless of whether regional lymph nodes are involved (T1NxMx). (medscape.com)
Highly aggressive gastric adenocarcinoma with multiple skin. (lww.com)
Although gastric adenocarcinoma is common in middle- and old-aged population, it is rare in young people. (lww.com)
We report the case of a 19-year young man with gastric adenocarcinoma who had multiple skin nodules over the trunk during presentation. (lww.com)
Fine-needle aspiration cytology of the nodule revealed it to be metastasis from gastric adenocarcinoma. (lww.com)
Gastric adenocarcinoma is one of the common causes of cancer death in the world. (lww.com)
SAN FRANCISCO ― An experimental monoclonal antibody combined with chemotherapy could offer a new standard of care for patients with claudin-18.2+ (CLDN18.2+) / HER2− advanced gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma, say researchers in reporting a phase 3 trial. (medscape.com)
First-line therapy for HER2− mG/GEJ adenocarcinoma generally consists of chemotherapy and immunotherapy, but among patients with advanced disease, the prognosis continues to be poor, and therapeutic options are limited. (medscape.com)

Genetic errors of the human caspase recruitment domain-B-cell lymphoma 10-mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (CBM) complex: Molecular, immunologic, and clinical heterogeneity. (medscape.com)
Rheumatoid Factor and Disease Activity Are Independent Predictors of Lymphoma in Primary Sjögren's Syndrome. (medscape.com)
Mucosa-associated lymphoid tissue lymphoma of the stomach: long term outcome after local treatment. (medscape.com)

Congratulations - you have completed Diseases of the Esophagus- Part 2 . (medquizzes.net)

We therefore set out to study gastric mucosa of patients with HD, looking for abnormalities of mucosal cells using immunohistochemistry. (cardiff.ac.uk)
Free radicals and oxidative stress play a central role in the generation and development of acute gastric mucosal lesions (AGML). (uwi.edu)
The extract could decrease distinctly the acute gastric mucosal damage index compared to the model group. (uwi.edu)

Genetic factors include a family history of gastric cancer, Li Fraumeni syndrome, and Type A blood type. (cdc.gov)

More vitamin B12 is released from its food matrix by the activity of hydrochloric acid and gastric protease in the stomach, where it then binds to haptocorrin [ 1 ]. (nih.gov)
In the stomach, B12 is uncoupled from its carrier protein due to the presence of gastric acid, which is why vitamin B12 deficiency is so commonly seen among those on chronic antacid medication. (wikidoc.org)
Once in the stomach, it is then bound to gastric R binder, a glycoprotein secreted by the salivary glands till it reaches the duodenum. (wikidoc.org)
For stomach (gastric) cancer, there is no standard or routine screening test for the general U.S. population. (oncolink.org)
The ulcer extends into the muscularis propria layer of the gastric epithelium and usually occurs in the stomach or duodenum. (obgproject.com)
Overview Note: Separate PDQ summaries on Stomach (Gastric) Cancer Screening, Gastric Cancer Treatment, and Levels of Evidence for Cancer Screening and Prevention Studies are also available. (cdc.gov)
14] Interventions for Reduction of Stomach (Gastric) Cancer Risk Smoking cessation Based on solid evidence, smoking is associated with an increased risk of stomach cancer. (cdc.gov)
Interventions With Inadequate Evidence as to Whether They Reduce the Risk of Stomach (Gastric) Cancer Diet Based on fair evidence, excessive salt intake and deficient dietary consumption of fresh fruits and vegetables are associated with an increased risk of gastric cancer. (cdc.gov)

Endoscopic submucosal dissection (ESD) is recommended for early GC which is limited to the mucosa and without lymph node metastasis, and gastrectomy with D2 lymphadenectomy is recommended for AGC ( 3 ). (frontiersin.org)
Patients with recurrence mainly present with distant metastasis, but localized recurrence is seen in 20%-40% of cases and involves the "gastric bed," the lymph nodes and/or the anastomosis, or the duodenal stump. (medscape.com)
Tumor size, histology, depth of invasion, and lymph node metastasis are the most significant prognosis factors in gastric cancer. (medscape.com)
Cutaneous metastasis may be the first presentation of internal malignancies even with a short history of disease in young patients. (lww.com)

However, it is not clear how HomB contributes to ulcer or gastric cancer, and the exact molecular mechanism is not been explored yet. (nature.com)
12,13] Compared with the general population, people with duodenal ulcer disease may have a lower risk of gastric cancer. (cdc.gov)

Patients with typical symptoms of gastroesophageal reflux disease (GERD) who do not have a history of PUD need not be tested for H. pylori infection. (guidelinecentral.com)

In autoimmune disease, the antibodies attack most of the gastric mucosa, but the antrum is spared. (wikidoc.org)

Gastric cancer (GC) is a common malignant tumor originating from gastric mucosa epithelial cells, and its onset is relatively insidious. (frontiersin.org)

More than 27,000 Americans are diagnosed with gastric cancer annually [8] . (mystateline.com)
In 2023, it is estimated that 26,500 Americans will be diagnosed with gastric cancer and 11,130 will die of it. (oncolink.org)
Two-thirds of people diagnosed with gastric cancer are older than 66 years. (oncolink.org)

HP is the causal factor for several clinically important diseases in gastric and duodenal mucosa ( 7 - 11 ), and, in 1994, the IARC expert group classified HP infection as a group-I carcinogen for humans ( 12 ). (iiarjournals.org)

sub>In addition, oral administration of absolute ethanol to mice significantly produced extensive hemorrhagic lesions of gastric mucosa, whereas animals pretreated with extract or ranitidine significantly reduced the formation of gastric lesions compared to control group. (uwi.edu)

To understand how the intestinal mucosa and regulation of incretin hormones are affected in patients subjected to gastric bypass surgery, an operation that often cures type 2 diabetes. (lu.se)

3 There is also evidence that after endoscopic therapy for early gastric cancer, H. pylori eradication reduces the risk of metachronous cancers. (ueg.eu)
the possibility that early gastric cancer might be present should always be kept in mind. (ueg.eu)

The validity of these measures was compared with Campylobacter-like organism analysis (gold standard) performed on patients requiring gastric biopsy. (who.int)

Yet, the expression pattern of vWF in human gastric cancer (GC) tissues and its relation to clinicopathological features of these cases remains unknown. (biomedcentral.com)

Prognosis appeared to correlate best with the stage of the disease rather than the histologic type. (nih.gov)
This prospective cohort study aims to investigate the incidence, related factors and prognosis of IgG4-related disease (IgG4-RD) with malignancies in the Chinese cohort. (nature.com)
The overall prognosis of gastric cancer is generally poor due to late presentation and diagnosis. (medscape.com)
One reason may be that claudin 18 positivity may be associated with a better prognosis for patients with diffuse gastric cancer, he explained. (medscape.com)
Oesophageal and gastric (OG) cancer are global health problems with poor prognosis. (cancercentrum.se)

As one of the most lethal malignant diseases, a strong correlation exists between GC and aberrant hemostasis. (biomedcentral.com)

Centers for Disease Control and Prevention. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)

In gastric mucosa from HD subjects, compared to control subject biopsies, a reduced expression of gastrin (a marker of G cells) was found. (cardiff.ac.uk)

Based on fair evidence, screening with barium-meal photofluorography or serum pepsinogen would not result in a decrease in mortality from gastric cancer in areas with relatively low incidence of the disease, such as the United States. (oncolink.org)
Accuracy of screening for gastric cancer using serum pepsinogen concentrations. (oncolink.org)
ins>and decreased the level of MDA in the serum and gastric tissues. (uwi.edu)
Chronic liver disease (CLD) patients, in- serum ELISA, rapid blood tests and sali- cluding those with viral hepatitis, autoim- vary ELISA, can be used in patients where mune hepatic disease and schistosomiasis, invasive procedures are contraindicated and have an impact on dental practice. (who.int)

Hamzaoui N, Pringault E. Interaction of microorganisms, epithelium, and lymphoid cells of the mucosa-associated lymphoid tissue. (medscape.com)

Although the etiological role of microorganisms in the pathogenesis of this disease is clear, the host's immune-inflammatory response can lead to protective and/or destructive effects on periodontal tissues 1 . (bvsalud.org)
Innumerous biological systems have been suggested as alternatives to modulate the host's immune-inflammatory response involved in periodontal disease 2 . (bvsalud.org)
Studies have demonstrated that, in the form of alcoholic extracts, decoctions, and infusions, C. verbenacea exhibits important anti-rheumatic, anti-inflammatory, analgesic, and healing properties which are related to a protective effect on the gastric mucosa, as well as very low toxicity when orally or topically administered 12-17 . (bvsalud.org)
Taking into account the extensive presence of C. verbenacea in Brazilian folk medicine, and considering the anti-inflammatory activity previously reported 12-17 our group was prompted to assess the impact of C. verbenacea in modulating periodontal disease progression. (bvsalud.org)

The etiology of pernicious anemia can be due to autoimmune causes or genetic disease. (wikidoc.org)

As most patients who have dyspepsia do not have a serious disease their symptoms can be managed conservatively, which avoids unnecessary and over treatment. (ueg.eu)
The majority of these complaints are due to functional dyspepsia or gastro-esophageal reflux disease (GERD), while a small minority are classified as organic in origin ( 4 , 6 ). (iiarjournals.org)

Chronic liver disease (CLD) patients, including those with viral hepatitis, autoimmune hepatic disease and schistosomiasis, have an impact on dental practice. (who.int)
This is because patients with chronic liver disease may ultimately develop serious liver dysfunction and this poses problems in performing non-invasive and invasive dental treatment procedures. (who.int)
There with chronic liver disease may ultimately are several studies on the residence of the develop serious liver dysfunction and this bacteria in the mouth and the possibility poses problems in performing non-invasive that dental plaque could be a source of re- and invasive dental treatment procedures. (who.int)
This activity has been planned and implemented through the joint providership of Medscape, LLC and Preventing Chronic Disease . (cdc.gov)

Gastric cancer (GC) is a leading contributor to global cancer incidence and mortality. (frontiersin.org)
Several trials have shown a reduction in the incidence of gastric cancer after eradication of H. pylori . (ueg.eu)
19] Only two studies assessed gastric cancer incidence as the primary study outcome, and two different studies were double blinded. (cdc.gov)
it was shown that short-term treatment with amoxicillin and omeprazole reduced the incidence of gastric cancer by 39% during a period of 15 years following randomization, with similar but not statistically significant reductions for gastric cancer mortality. (cdc.gov)

Magnitude of Effect: A systematic review and meta-analysis showed a 60% increase in gastric cancer in male smokers and a 20% increase in gastric cancer in female smokers compared with nonsmokers. (cdc.gov)

Gastric cancer treatment depends on tumor type, stage, and general health of the patient. (medscape.com)
Most of the undifferentiated GC tumor tissues at late disease stage exhibited strong VEGF and VEGFR2 protein staining, which co-localized with the vWF protein staining pattern. (biomedcentral.com)
Zolbetuximab is a monoclonal antibody that targets the cell surface molecule CLDN18.2, which is expressed in normal gastric mucosa cells and is retained in mG/GEJ tumor cells. (medscape.com)

H. Pylori infection eradication Based on solid evidence, H. pylori infection is associated with an increased risk of gastric cancer. (cdc.gov)

By contrast, the 'test and scope' strategy directs patients to undergo gastroscopy to evaluate H.-pylori-related diseases, namely for older patients or those with alarm symptoms. (ueg.eu)
Multiple studies have also demonstrated that removal of the organism by antimicrobial therapy is correlated with the resolution of symptoms and cure of diseases. (rapidtest.com)
Also, partial presentations (an absence of some of the following signs/symptoms) do not necessarily imply less severe disease. (cdc.gov)
Dyspeptic symptoms are among the most common gastric complaints ( 1 ), experienced by 25-40% of the people during their lifetime ( 1 , 2 ). (iiarjournals.org)

Patients with MALTomas often have a history of an associated autoimmune disease. (medscape.com)

The biological effects of exposure to this plant within the gastric carcinogenesis process are not fully understood. (pasteur.fr)
The gene transcription alterations and the induced glycophenotypic changes observed in the gastric mucosa contribute for the understanding of the molecular mechanisms underlying the role of Pteridium aquilinum in the gastric carcinogenesis process. (pasteur.fr)

Treatment continued until disease progression or discontinuation criteria were met. (medscape.com)

Thus, we evaluated the recurrence rate of gastric hyperplastic. (koreamed.org)

Gastric cancer is one of the most common cancers in Korea and the world. (koreamed.org)

Five were Mediterranean-type lymphomas associated with plasma cell infiltration of the adjacent mucosa, and only two cases of primary Hodgkin's disease were encountered. (nih.gov)

In order to investigate possible histological differences related to gastric acid production, we evaluated the cell density of acid producing parietal cells, as well as gastrin producing cells (the endocrine cell controlling parietal cell function). (cardiff.ac.uk)
Background/Aims: Tegoprazan, a novel potassium-competitive acid blocker, has shown rapid action and gastric acid inhibition. (koreamed.org)

HomB and HomA are the most studied OMPs from H. pylori as they play a crucial role in adherence, hyper biofilm formation, antibiotic resistance and are also associated with severe gastric malignancies. (nature.com)

Epidemiological studies have shown an association between bracken fern exposure and gastric cancer development in humans. (pasteur.fr)

By identifying type 2 diabetes-induced alterations we foresee that we will understand both the causes of the disease and the body's own defense mechanisms that try to counteract disease development. (lu.se)
We aim to identify type 2 diabetes-induced, cell type-specific alterations in islet and intestinal cells that explain why the disease develops. (lu.se)

Anatomy29

Organisms12

Diseases30

Chemicals and Drugs47

Analytical, Diagnostic and Therapeutic Techniques and Equipment14

Phenomena and Processes4

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Humanities1

Gastritis19

Helicobacter11

Peptic6

Advanced gastric cancer4

MALT1

Ulcers5

Endoscopy3

Gastrointestinal5

Adenocarcinoma8

Lymphoma3

Esophagus1

Mucosal3

Family history of gastric cancer1

Stomach8

Metastasis4

Ulcer2

Gastroesophageal1

Antrum1

Epithelial cells1

Diagnosed with gastric cancer3

Duodenal1

Lesions1

Intestinal Mucosa1

Early gastric cancer2

Biopsy1

Human gastric cancer1

Prognosis5

Malignant1

Centers for Diseas2

Biopsies1

Serum4

Epithelium1

Inflammatory4

Pernicious anemia1

Dyspepsia2

Chronic4

Incidence4

Magnitude of Effect1

Tumor3

Pylori infection1

Symptoms4

Autoimmune1

Carcinogenesis2

Progression1

Hyperplastic1

Cancers1

Lymphomas1

Acid2

Malignancies1

Humans1

Alterations2