• optic
  • Failure of the cells of the posterior portion of the optic vesicles to express growth hormone affects the differentiation of other cells of the eye. (wikipedia.org)
  • The choroid, especially lateral to the optic disc, is hypoplastic (underdeveloped). (wikipedia.org)
  • The most common sign of CEA is the presence of an area of undeveloped choroid (appearing as a pale spot) lateral to the optic disc. (wikipedia.org)
  • Optic neuritis , or swelling of the optic disk, is considered a very serious condition that could be life threatening, and as such, great care must be taken to help your dog to maintain proper health. (petmd.com)
  • Diagnosis
  • Because these signs are vague and can be mistaken for other conditions, it's easy to miss this disease as a diagnosis until it reaches more advanced stages. (canna-pet.com)
  • Molecular genetic testing can aid in the diagnosis of the affected individual, which would determine if there are any abnormalities in the FGF3 gene (11q13) or the FADD gene (11q13.3). (wikipedia.org)
  • citation needed] Studies by Cohen show that up to 25% of all low back pain is sacroiliac joint in origin and that the diagnosis of sacroiliac joint disease is frequently overlooked by physicians. (wikipedia.org)
  • dog's
  • The degree of these abnormalities varies between individual dogs, and even between the same dog's eyes. (wikipedia.org)
  • The test can determine whether a dog is affected, a carrier, or clear, and is therefore a useful tool in determining a particular dog's suitability for breeding. (wikipedia.org)
  • Although working Border Collie handlers sometimes have superstitions about the appearance of their dogs (handlers may avoid mostly white dogs due to the unfounded idea that sheep will not respect a white or almost all white dog), in general a dog's appearance is considered by the American Border Collie Association to be irrelevant. (wikipedia.org)
  • Exophthalmos, enophthalmos, and strabismus are all diseases which cause the dog's eyeball to be abnormally positioned. (petmd.com)
  • coloboma
  • A coloboma may be small and have very little effect on vision, or it can be a larger hole that takes away too much of the eye structure and leads to partial or full blindness, or to retinal detachment. (petmd.com)
  • Otodental syndrome, also known as otodental dysplasia, is an exceptionally rare disease that is distinguished by a specific phenotype known as globodontia, that in rare cases can be associated with eye coloboma and high frequency hearing loss. (wikipedia.org)
  • secondary
  • More severe symptoms include: Globodontia - an abnormal condition that can occur in both primary and secondary tooth development, in which the molars and canines are greatly enlarged. (wikipedia.org)
  • Symptoms
  • Up to 80 percent of dogs infected will have symptoms, but the mortality rate is only 5 to 8 percent. (wikipedia.org)
  • Symptoms and treatment for kidney disease vary depending the specifics of the case, but oftentimes, a diet change can help. (petmd.com)
  • While a veterinarian can determine through genetic analysis whether your dog has this defect, there may be no symptoms, until the onset of blindness signals you to the problem. (petmd.com)
  • If your horse has developed moon blindness, he will exhibit symptoms characteristic of the disease. (wagwalking.com)
  • Other possible, less severe, symptoms involve: Absent premolars - individuals suffering from otodental syndrome will typically lack the ability to develop premolars due to its genetic related affects. (wikipedia.org)
  • tissue
  • However, since this is an immune-mediated disease, the horse's cells may continue fighting and attacking the tissue of the eye and between flare-ups. (wagwalking.com)
  • Collies
  • Approximately 70 to 97 percent of rough and smooth collies in the United States and Great Britain are affected, and approximately 68 percent of rough collies in Sweden are affected. (petmd.com)
  • abnormality
  • The parents may not be affected by the mutation, and may therefore not have been diagnosed with the abnormality, but offspring can be affected, especially when both parents carry the mutation. (petmd.com)
  • Neurodegenerative disorders are diseases associated with an abnormality in the metabolic pathway that leads to early death of the neuron. (cynologist.com)
  • Since the choroid layer does not develop normally from the start, the primary abnormality can be diagnosed at a very young age. (collie-online.com)
  • inflammatory
  • In dogs, this condition is almost always caused by an allergic reaction to something in the environment, which in turn causes an inflammatory response in the upper airways. (canna-pet.com)
  • commonly
  • While black and white is the most commonly seen colour pattern of the Border Collie, the breed appears in just about any colour and pattern known to occur in dogs. (wikipedia.org)
  • Vaccination of dogs for rabies is commonly required by law. (wikipedia.org)
  • It most commonly occurs in dogs in close confinement such as kennels. (wikipedia.org)
  • The disease in dogs can affect the lungs and skin, but more commonly the eye and central nervous system. (wikipedia.org)
  • As such, vestibular signs are commonly encountered in affected animals. (cynologist.com)
  • Although now not commonly encountered, a deficiency of thiamine (Vitamin B1) can cause a progressive encephalopathy in both dogs and cats. (cynologist.com)
  • often
  • They are often cited as the most intelligent of all domestic dogs. (wikipedia.org)
  • As this is a bilaterally symmetrical disease, the vestibular signs often present as wide excursions of the head and neck with poor to absent physiological nystagmus. (cynologist.com)
  • It's thought of as a puppy disease, and often clears up on its own. (canna-pet.com)
  • breeds
  • The condition is most frequently seen in the Lhasa apso, Shih Tzu, Pekingese, poodle, and Chinese pug dog breeds and infrequently in the Persian cat. (cynologist.com)
  • intense
  • Allergies can cause intense itching and discomfort, which means dogs will dig and chew sometimes till they bleed. (canna-pet.com)
  • normally
  • Atopy is an allergic skin condition in dogs caused by exposure to normally innocuous substances in the environment such as house dust mite, pollen from trees, flowers or grasses and mould spores that are absorbed through the skin or inhaled. (allcreaturesvetbroome.com.au)
  • puppy
  • This can be done when your dog is still a puppy, ans is recommended. (petmd.com)
  • genetic
  • The American Academy of Veterinary Dermatology recommends neutering or spaying all dogs that develop generalized demodectic mange because there is a genetic link. (canna-pet.com)
  • infection
  • There is an increased risk of infection associated with amount of time spent outdoors, a larger roaming space accessed by the dog, and increasing age. (wikipedia.org)
  • veterinarian
  • When treating your dog or cat at home without consulting a veterinarian, you could be putting your beloved pet's health in jeopardy. (petmd.com)
  • disorders
  • An individual may be predisposed to the development of FBS due to systemic disorders such as diabetes, autoimmune disease and peripheral blood vessels (vascular) disease. (wikipedia.org)
  • Genomics
  • NEIBank is a unified resource for understanding what is known about gene expression in the eye, providing tools for identifying cDNA clones for functional studies, and examining the genomics of human eye disease. (molvis.org)
  • area
  • According to a study performed in the Tucson and Phoenix area, 28% of dogs will test positive for exposure to the fungus by two years of age, but only 6% of the dogs will be ill with clinical disease. (wikipedia.org)
  • adrenal
  • It can be due to an imbalance of the pituitary or adrenal gland, or it can occur when a dog has too much cortisol resulting from other conditions. (canna-pet.com)