Disease sputum. Medical search. Frequent questions

After 2 months of treatment, 71% of M. bovis and 65% of M. tuberculosis TB patients showed conversion of sputum cultures to negative. (cdc.gov)
Studies have demonstrated that sputum-culture conversion differs by M. tuberculosis phylogenetic lineage ( 14 , 15 ). (cdc.gov)
We evaluated differences in time from treatment initiation to sputum-culture conversion between patients with M. bovis TB and M. tuberculosis TB given standard first-line anti-TB treatment. (cdc.gov)
We analyzed data from the National Tuberculosis Surveillance System (NTSS) at the Centers for Disease Control and Prevention (Atlanta, GA, USA) and restricted analysis to cases reported during 2006-2013 to permit sufficient time for follow-up reporting of outcome data. (cdc.gov)
Pooling sputum specimens is one potential strategy for reducing the cost of using Xpert MTB/RIF, a rapid polymerase chain reaction (PCR)-based test, for the diagnosis of pulmonary tuberculosis. (biomedcentral.com)
We have confirmed that pooling of two sputum specimens for testing in a single cartridge is a valid method of reducing the number of cartridges required when using Xpert MTB to detect pulmonary tuberculosis. (biomedcentral.com)
Zishiri and colleagues have shown, in 20 acid-fast bacilli smear positive and 17 smear negative sputum specimens that were Mycobacterium tuberculosis (MTB) culture positive and Xpert MTB positive, that pooling up to five-fold (that is, each with four negative sputum samples collected from other individuals) was associated with acceptable sensitivity when implemented in a reference laboratory [ 7 ]. (biomedcentral.com)
In some screening settings, such as general community-wide screening, the prior probability of TB will be lower and likely concentration of M. tuberculosis in sputum specimens submitted for testing will be lower. (biomedcentral.com)
Hence, it is encouraging that we have shown, using sputum specimens spiked with a low concentration of M. tuberculosis and diluted from 2- to 12-fold that, despite an expected linear increase in cycle threshold with increasing dilution, the majority of diluted specimens were still Xpert MTB positive [ 9 ]. (biomedcentral.com)
citation needed] Microbiological sputum samples are used to look for infections, such as Moraxella catarrhalis, Mycobacterium tuberculosis, Streptococcus pneumoniae, and Haemophilus influenzae. (wikipedia.org)
Direct sputum smear microscopy is the mainstay of TB diagnosis in most low and middle income countries, and is highly specific for Mycobacterium tuberculosis in such settings. (biomedcentral.com)
A recent study reported encouraging performance of ligand-coated magnetic beads in combination with FM, in detection of M. tuberculosis in a panel of frozen sputum samples, with good correlation reported between magnetic bead concentration and centrifugation [ 7 ]. (biomedcentral.com)
A positive culture may identify disease-producing organisms that may help diagnose bronchitis, tuberculosis, a lung abscess, or pneumonia. (mountsinai.org)
Tuberculosis (TB) is a potentially fatal contagious disease that can affect almost any part of the body but is mainly an infection of the lungs. (encyclopedia.com)
Tuberculosis properly refers only to disease caused by Mycobacterium tuberculosis (for which humans are the main reservoir). (merckmanuals.com)
If tuberculosis is suspected, an acid-fast stain should be performed immediately, and the sputum cultured on special media, which are incubated for at least 6 weeks. (medscape.com)
International Union against Tuberculosis and Lung Disease. (who.int)
Technical guide : sputum examination for tuberculosis by direct microscopy in low income countries. (who.int)
76.3% were pulmonary tuberculosis and 36.9% were sputum smear-positive cases. (who.int)
Earlier and improved tuberculosis (TB) case detection - including smear-negative disease, often associated with HIV co-infection - as well as expanded capacity to diagnose multidrug-resistant tuberculosis (MDR-TB) are global priorities for TB control. (bvsalud.org)
Xpert MTB/RIF detects M. tuberculosis as well as rifampicin resistance-conferring mutations directly from sputum, in an assay providing results within two hours. (bvsalud.org)
Results from analytical studies showed that the Xpert MTB/RIF assay has analytic sensitivity of five genome copies of purified DNA, and 131 cfu/ml of M. tuberculosis spiked into sputum. (bvsalud.org)

Although cough and sputum production may impact patients' well being and functioning in COPD and chronic bronchitis, there is no validated instrument for cough and sputum symptoms and their impact on patients' daily activities. (nih.gov)
These data indicate that the CASA-Q may be a useful measure of cough and sputum production, and their impact in patients with COPD and/or chronic bronchitis. (nih.gov)
1 2 It is heterogeneous, but many patients experience progressive airflow obstruction, exacerbations and/or persistent symptoms of dyspnoea, cough and sputum production. (bmj.com)
CT thorax scan of a 77-year-old woman who presented with chronic cough and sputum production, without a history of underlying preexisting lung disease. (medscape.com)
A study of long-COVID patients in Japan links severe infection to persistent cough and sputum production. (umn.edu)

Chronic obstructive pulmonary disease (COPD) is characterized by significant chronic inflammation in the pulmonary compartment as well as in the circulation. (nih.gov)
This study aimed to elucidate the relationship between local and systemic inflammation in smoking-induced COPD by assessing levels of soluble (s) tumor necrosis factor (TNF) receptors, TNF-alpha, and interleukin-8 (IL-8) in induced sputum and in plasma. (nih.gov)
Sputum induction was performed in 18 subjects with COPD (FEV(1) 56% predicted) and 17 healthy smokers (FEV(1) 99% predicted). (nih.gov)
Patients with COPD showed significantly higher percentages of neutrophils and levels of sTNF-R55 and IL-8 in sputum as compared with control subjects, whereas sputum sTNF-R75 levels tended to be higher in COPD. (nih.gov)
When comparing sTNF receptors in sputum and plasma, no direct correlations were found despite elevation of circulating sTNF-R75 levels in patients with COPD. (nih.gov)
In addition, sputum sTNF receptors were inversely related to the FEV(1) in patients with COPD, whereas circulating sTNF receptors were not, suggesting different regulation of inflammation in the pulmonary and systemic compartment. (nih.gov)
When subjects were divided according to their current smoking status, levels of sTNF-R55, sTNF-R75, and IL-8 in sputum were significantly elevated in ex-smoking versus currently smoking patients with COPD, suggesting ongoing inflammation in airways and circulation of patients with COPD after smoking cessation. (nih.gov)
To fill that gap, we developed and validated a specific, multilingual Cough and Sputum Assessment Questionnaire (CASA-Q) that evaluates clinical symptoms and their impact on patients with COPD or chronic bronchitis. (nih.gov)
Introduction Oscillating positive expiratory pressure (OPEP) devices are intended to facilitate sputum clearance in chronic obstructive pulmonary disease (COPD), but there is uncertainty as to their place in treatment pathways. (bmj.com)
Does the use of oscillating positive expiratory pressure (OPEP) devices impact health-related quality of life and symptoms, exacerbations, lung function parameters and exercise capacity, compared with usual care or alternative sputum clearance techniques in people with chronic obstructive pulmonary disease (COPD)? (bmj.com)
Productive cough due to mucus hypersecretion is a common feature in people with chronic obstructive pulmonary disease (COPD). (bmj.com)
The contribution of the microbiome to chronic obstructive pulmonary disease (COPD) pathobiology and the potential for microbiome-based clinical biomarkers in COPD are still in the early phases of investigation. (bmj.com)
Sputum is an easily obtainable sample and has provided a wealth of information on COPD pathobiology, and thus has been a preferred sample type for microbiome studies. (bmj.com)
Although the sputum microbiome likely reflects the respiratory microbiome only in part, there is increasing evidence that microbial community structure and diversity are associated with disease severity and clinical outcomes, both in stable COPD and during the exacerbations. (bmj.com)
This review provides an overview of the basic principles of high-throughput microbiome sequencing techniques, current literature on sputum microbiome profiling in COPD, and a discussion of the associated limitations and future perspectives. (bmj.com)
Chronic obstructive pulmonary disease (COPD) is a highly prevalent respiratory disease and the leading cause of morbidity and mortality worldwide. (bmj.com)
Llame al 866.731.COPD (2673) y presione 9 para hablar en español con un paciente o cuidador. (copdfoundation.org)
The forced expiratory volume in 1 sec (FEV1) is the most established outcome measure in chronic obstructive pulmonary disease (COPD). (ox.ac.uk)
Little is known about the repeatability of these measures or the safety of sputum induction in COPD. (ox.ac.uk)
We have assessed the safety of sputum induction in 61 subjects with moderate and severe COPD who participated in a placebo-controlled cross-over study The within-subject repeatability of sputum markers of airway inflammation, health status using the chronic respiratory disease questionnaire (CRQ) and symptom visual analogue scores (VAS) were estimated from the data obtained from before and after 2 weeks of treatment with placebo. (ox.ac.uk)
In conclusion, sputum induction is safe and the cell and fluid phase mediators repeatable in the investigation of airway inflammation in patients with COPD. (ox.ac.uk)
In this study we looked at smokers with and without chronic obstructive pulmonary disease (COPD) patients in order to evaluate the incidence of 4977 base pair (bp) mtDNA (mtDNA(4977)) deletion and mtDNA copy number in sputum cells and in peripheral blood leukocytes (PBLs) in relation to mitochondrial function and oxidative stress status. (medipol.edu.tr)
Levels of cellular oxidative stress were significantly higher in the sputum cells of subjects with COPD than in the smoker group. (medipol.edu.tr)
Our studies may suggest that the accumulation of mtDNA(4977) in the sputum cells of smokers with COPD does not seem to have an important impact on mitochondrial dysfunction in relation to ATP production and Delta Psi m when compared to those of healthy smokers. (medipol.edu.tr)
It is estimated about 16 million adults in the United States have COPD , and it is the sixth leading cause of death in the U.S. according to the Centers for Disease Control (CDC). (medicinenet.com)
Infectious diseases that destroy lung tissue in patients with hyperactive airways or asthma also may contribute to COPD. (medicinenet.com)
What other diseases or conditions contribute to COPD? (medicinenet.com)
Chronic Obstructive Pulmonary Disease (COPD) is a group of lung diseases, including emphysema and chronic bronchitis. (bidmc.org)
Our COPD and Emphysema Clinic provides the latest treatment options for patients with advanced chronic obstructive pulmonary disease (COPD). (bidmc.org)
We offer a comprehensive physical therapy program for people with COPD and other lung diseases whose daily activities are limited because of shortness of breath. (bidmc.org)
The Standards for the Diagnosis and Treatment of Patients with COPD document 2004 updates the position papers on chronic obstructive pulmonary disease (COPD) published by the American Thoracic Society (ATS) and the European Respiratory Society (ERS) in 1995 1 , 2 . (ersjournals.com)
5) Both the ATS and the ERS acknowledge the recent dissemination of the Global Initiative of Obstructive Lung Disease (GOLD) 3 as a major worldwide contribution to the battle against COPD. (ersjournals.com)
The main goals of the updated document are to improve the quality of care provided to patients with COPD and to develop the project using a disease-oriented approach. (ersjournals.com)
and promote the concept that COPD is a treatable disease. (ersjournals.com)
COPD, a chronic inflammatory lung disease that causes obstructed airflow from the lungs, includes chronic bronchitis and emphysema. (mayoclinic.org)
At least 16 million Americans have chronic obstructive pulmonary disease (COPD) , and many more may not know they're living with it. (bestcare.org)
COPD is a progressive disease, and it will inevitably cause irreversible damage. (bestcare.org)
In fact, the Centers for Disease Control and Prevention (CDC) lists COPD as an underlying medical condition that puts you at a higher risk for severe illness if you have COVID-19. (bestcare.org)
People with COPD are at higher risk for serious issues from certain vaccine-preventable diseases. (bestcare.org)
It helps detect pulmonary obstruction, caused by conditions such as chronic obstructive pulmonary disease (commonly termed COPD) or asthma. (aidsmap.com)
In patients with known chronic obstructive pulmonary disease (COPD), exacerbations occur an average of 1.3 times per year. (aafp.org)
Antibiotics should be used in patients with moderate or severe COPD exacerbations, especially if there is increased sputum purulence or the need for hospitalization. (aafp.org)
The choice of antibiotic in patients with COPD should be guided by symptoms (e.g., presence of purulent sputum), recent antibiotic use, and local microbial resistance patterns. (aafp.org)
4 , 5 In addition to the hallmark symptoms of a COPD exacerbation (cough, dyspnea, and increased sputum), systemic inflammation also causes extrapulmonary symptoms ( Table 2 ). (aafp.org)
You might also have bronchiectasis, emphysema, chronic bronchitis, or chronic obstructive pulmonary disease (COPD) to name a few. (asthma.org.au)
COPD Cause: Why are non-smokers at the risk of chronic obstructive pulmonary disease? (indiatimes.com)
Chronic Obstructive Pulmonary Disease (COPD) is a group of chronic inflammatory lung diseases that leads to obstructed airflow from the lungs making it difficult to breathe. (indiatimes.com)
Overexposure to these pollutants can exacerbate symptoms of patients with pre-existing respiratory illnesses like asthma, and even make way for newer cases of respiratory diseases including COPD. (indiatimes.com)
All the above confirms that COPD is no longer just a smoker's disease, but a silent threat that looms over the general population as well. (indiatimes.com)
Your doctor will perform a physical exam to rule out other possible conditions, such as a respiratory infection or chronic obstructive pulmonary disease (COPD). (mayoclinic.org)
Definition: COPD is a progressive disease that makes it hard to breathe. (bartleby.com)
Chronic obstructive pulmonary disease (COPD) is in the top five principal cause of death in the U.S. The disease is an abnormal inflammatory reaction in the lungs with limited airflow. (bartleby.com)
These NCDs include cardiovascular diseases (e.g. hypertension, heart attack and stroke), diabetes, chronic respiratory disease (e.g. chronic obstructed pulmonary disease or COPD,) and cancer. (who.int)
COPD cough in the long run and sputum production but symptoms don't respond and COV=D? (who.int)

You will produce a sputum sample from your lungs by coughing up mucus from deep inside your lungs. (medlineplus.gov)
Sputum is mucus that is coughed up from the lower airways (the trachea and bronchi). (wikipedia.org)
Sputum, or phlegm, is a mixture of saliva and mucus that you've coughed up. (healthline.com)
Symptoms include difficulty breathing, cough, mucus (sputum) production and wheezing. (aidsmap.com)
Mucus hypersecretion with abnormal mucus consistency and reduced mucociliary clearance occurs in respiratory diseases like cystic fibrosis (CF), respiratory distress syndrome (RDS) of the newborn, chronic obstructive pulmonary disease, asthma and also in heavy smokers. (karger.com)
In the airways, the disease causes difficulties in breathing and coughing up mucus. (karger.com)
This test looks for certain white blood cells (eosinophils) in the mixture of saliva and mucus (sputum) you discharge during coughing. (mayoclinic.org)

The mean CASA-Q cough symptom and sputum symptom domain scores indicated responsiveness towards both worse and improved symptoms, whereas the impact domains scored already in the upper third of the scale range, indicating the need for further improvement of its properties. (nih.gov)
Differences in the CASA-Q domain scores by smoking status (current vs. former smokers) were highest for cough symptoms and lowest for sputum impact. (nih.gov)
Symptoms and Management of Coronavirus Disease 2019 (COVID-19) FAQ: What are the signs and symptoms of coronavirus disease 2019 (COVID-19)? (medscape.com)
What are the signs and symptoms of severe or critical coronavirus disease 2019 (COVID-19)? (medscape.com)
Patients with a mild clinical presentation may not initially require hospitalization, but clinical signs and symptoms may worsen, with progression to lower respiratory tract disease in the second week of illness. (medscape.com)
Patients with mild coronavirus disease 2019 (COVID-19) should be counseled regarding the signs and symptoms of complicated disease. (medscape.com)
However, changes in FEV1 in response to treatment are small in relation to the repeatability of the measurement and there is increasing interest in other measures including markers of lower airway inflammation in induced sputum, assessment of symptoms and health status using visual analogue scores, and questionnaires. (ox.ac.uk)
20% and at a further 13 visits the full sputum induction protocol was not completed due to development of symptoms. (ox.ac.uk)
The test may also be done if you have other signs and symptoms of respiratory disease or infection. (mountsinai.org)
For each disease the symptoms, prevention and transmission methods and treatment options are discussed so that IAFF members can protect themselves in the workplace. (iaff.org)
Visit your health care provider for a check-up if you have symptoms of TB disease or want to know if you have latent TB infection. (bccdc.ca)
Increased breathlessness, increased sputum volume and purulent sputum are the signs and symptoms of exacerbation. (bartleby.com)
NSCLC is often insidious, producing no symptoms until the disease is well advanced. (medscape.com)
[ 59 ] A controlled prospective study has shown that adjusting inhaled corticosteroid (ICS) treatment to control sputum eosinophilia-as opposed to controlling symptoms, short-acting beta-agonist (SABA) use, nocturnal awakenings, and pulmonary function-significantly reduced both the rate of asthma exacerbations and the cumulative dose of inhaled corticosteroids. (medscape.com)

Having green, yellow, or thickened phlegm (sputum) does not always indicate the presence of an infection. (wikipedia.org)
Also, if an infection is present, the color of the phlegm (sputum) does not determine whether a virus, a bacterium or another pathogen has caused it. (wikipedia.org)

We used a retrospective cohort study design and included culture-confirmed TB cases with complete genotyping results and pulmonary disease treated with a standard 4-drug regimen (i.e., isoniazid, rifampin, ethambutol, and pyrazinamide) at diagnosis ( 19 ). (cdc.gov)
Furthermore, microscopy is a multi-disease platform that can be used for diagnosis of a number of diseases of public health importance. (biomedcentral.com)
Because many laboratories do not possess the special assays necessary to identify NTM subspecies, this pilot program used a full-service mycobacteriology laboratory equipped with these assays at National Jewish Health in Denver to ensure accurate diagnosis and targeted treatment for NTM lung disease. (copdfoundation.org)
Specimen collection and handling for diagnosis of infectious diseases. (mountsinai.org)
Diagnosis is most often by sputum smear and culture and, when available, by nucleic acid amplification tests. (merckmanuals.com)
To get an accurate diagnosis and evaluate the disease severity early-on, visiting your doctor to request a spirometry test is the best course of action. (indiatimes.com)
At initial diagnosis, 20% of patients have localized disease, 25% of patients have regional metastasis, and 55% of patients have distant spread of disease. (medscape.com)

Cough suppressants can lead to airway obstructions or keep the sputum trapped in your lungs, prolonging or worsening an infection. (healthline.com)
A sputum sample is obtained by coughing deeply and expelling the material that comes from the lungs into a sterile cup. (mountsinai.org)
You will be asked to cough deeply and spit any substance that comes up from your lungs (sputum) into a special container. (mountsinai.org)
Chronic obstructive pulmonary disease is a slowly progressive obstruction of airflow into or out of the lungs . (medicinenet.com)
Beryllium where scarring prevents oxygen · cough, Disease (CBD) from moving freely from the lungs · shortness of to the blood. (cdc.gov)
TB Disease usually lives in people's lungs (pulmonary TB), but it can live anywhere in the body (extra pulmonary TB). (bccdc.ca)
A test used to diagnose or monitor lung disease, measuring how much air a person can force out of their lungs in one second. (aidsmap.com)

Sputum culture grew Mycobacterium avium complex. (medscape.com)
In the United States, Mycobacterium avium-intracellulare (MAI, or MAC) infection is considered a nonreportable infectious disease. (medscape.com)
Peptide nucleic acid-fluorescence in situ hybridization (PNA-FISH) assay for specific detection of mycobacterium immunogenum and DNA-FISH assay for analysis of pseudomonads in metalworking fluid s and sputum. (cdc.gov)
Here, we report for the first time a species-specific peptide nucleic acid-fluorescence in situ hybridization (PNA-FISH) method for Mycobacterium immunogenum, a non-tuberculous Mycobacterium species prevalent in MWF and implicated in occupational lung disease hypersensitivity pneumonitis and pseudo-outbreaks. (cdc.gov)
4,5 COVID-19 infection can also increase the CASE SERIES risk of progression to TB disease or reactivation of previous TB, either due to the immunosuppressive COVID-19 and Mycobacterium coinfection effects of COVID-19 or from treatment, such as the use of steroids. (who.int)

Sputum transcriptomics data from 120 subjects with severe asthma (SA) who were smokers (SAsm) or non-smokers (SAn), mild moderate asthmatics (MMA) or healthy controls (HC). (ersjournals.com)
Who is at risk for severe coronavirus disease 2019 (COVID-19)? (medscape.com)
Here, we investigated this possibility by characterizing the microbial composition in the sputum of 334 TB patients from Tanzania, and by assessing its association with three aspects of disease manifestations: sputum mycobacterial load, severe clinical findings, and chest x-ray (CXR) findings. (unibas.ch)
Objective To evaluate viral loads at different stages of disease progression in patients infected with the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first four months of the epidemic in Zhejiang province, China. (bmj.com)
Participants 96 consecutively admitted patients with laboratory confirmed SARS-CoV-2 infection: 22 with mild disease and 74 with severe disease. (bmj.com)
strongly recommended in severe or progressive disease. (who.int)
Introduction: A cluster of pneumonia cases of unknown origin was first reported in Wuhan China then the causa- tive pathogen was identified and named severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) and the associated disease was named coronavirus disease 2019 (COVID-19). (who.int)
COVID-19 with evidence of worsening of respiratory navirus 2 (SARS-CoV2) and the associated disease status and for patients with moderate to severe features was named coronavirus disease 2019 (COVID-19). (who.int)
a 42-year-old man with diabetes mellitus, chronic kidney disease and hypertension who had severe COVID-19 and needed urgent dialysis and supplemental oxygen. (who.int)

Various physical and chemical sputum processing methods have been identified which can improve the sensitivity of microscopy. (biomedcentral.com)
Fluorescence microscopy (FM) gives an average increase of 10% sensitivity over the ZN method, while retaining specificity [ 4 ], a finding which has had little relevance in disease endemic countries until the recent development of inexpensive fluorescence microscopes illuminated by light emitting diodes (LEDs). (biomedcentral.com)
They disperse primarily through coughing, singing, and other forced respiratory maneuvers by people who have active pulmonary or laryngeal TB and whose sputum contains a large number of organisms (about 10,000 organisms/mL, the limit of detection by fluorescent microscopy). (merckmanuals.com)
Quality assurance of sputum microscopy in DOTS programmes : regional guidelines in countries in the Western Pacific. (who.int)

And last, the detection of herpesviruses and anelloviruses in sputum microbial assemblage was linked to co-infection with HIV. (unibas.ch)
However, The development of TB may not only be determined by the primary agent of the disease but also governed by the interaction of local microbial communities and immunological factors [ 5 , 9 ]. (springer.com)

Red, jelly-like sputum - an indicator of possible pneumonia caused by Klebsiella. (wikipedia.org)
If part of a cluster of pneumonia (or there are other reasons to consider at higher risk for SARS-CoV disease), consider SARS-CoV testing in consultation with health department. (cdc.gov)
If clinicians have concerns about the possibility of SARS-CoV disease in a patient with a history of travel to other previously affected areas (e.g., while traveling abroad, had close contact with another person with pneumonia of unknown etiology or spent time in a hospital in which patients with acute respiratory disease were treated), they should contact the health department. (cdc.gov)

If coughing does not produce sputum, a breathing treatment may be given before the test to trigger sputum production. (medlineplus.gov)
This makes you cough more deeply and produce sputum. (mountsinai.org)

Specimen adequacy is assessed by the laboratory technologists by examining a Gram stain or cytology stain of the sputum. (wikipedia.org)
When a sputum specimen is plated out in microbiology, it is best to get the portion of the sample that almost looks like yellow pus onto the swab. (wikipedia.org)
Whitish gray sputum color against a white color background (such as a white sink surface) tends to indicate either a specimen from someone who is dehydrated, and/or from an older person, and/or a specimen with a mixed, modest number of eosinophils and maybe some acute inflammatory neutrophil cells (this last choice tends to suggest chronic allergic bronchitis). (wikipedia.org)
Once the patient was able to collect a quality sputum sample, they mailed their specimen directly to the laboratory at National Jewish Health using the pre-paid label included within their kit. (copdfoundation.org)

The disease can develop over a long period of time without causing shortness of breath. (bidmc.org)

Blood-tinged sputum can sometimes be a symptom of an underlying condition that you can't prevent. (healthline.com)
Physicians should consider antibiotics for patients with purulent sputum and for patients who have inadequate symptom relief with bronchodilators and corticosteroids. (aafp.org)

1) chronic bronchitis , 2) emphysema, and 3) infectious diseases of the lung. (medicinenet.com)
Chronic bronchitis and emphysema are thought to be variations of chronic obstructive pulmonary disease and are considered part of the progression of chronic obstructive pulmonary disease by many researchers. (medicinenet.com)
Chronic bronchitis is defined as a chronic cough that produces sputum for three or more months during two consecutive years. (medicinenet.com)
Chronic bronchitis can cause a cough that brings up colored sputum. (mayoclinic.org)

The best sputum samples contain very little saliva, as saliva contaminates the sample with oral bacteria. (wikipedia.org)
The client should be instructed to avoid adding saliva or nasopharyngeal secretions to the sputum sample. (medscape.com)

[ 1 ] Although the prevalence of MAI infection has increased following the epidemic of acquired immunodeficiency syndrome (AIDS), MAI infection remains a rare cause of skin disease. (medscape.com)
This coincidence concords with the fact that DMAI infection often occurs in association with HIV disease. (medscape.com)
A review of 8 cases of cutaneous MAI infection occurring secondary to disseminated disease found a median patient age of 22.2 years, with a range of 2-28 years. (medscape.com)
The fire department must establish procedures for the evaluation of work limitations for employees with an infectious disease who in the course of performing their duties demonstrate evidence of functional impairment or inability to adhere to standard infection control practices or who present an excessive risk of infection to patients or fire department members. (iaff.org)
Many elderly patients developed the infection some years ago when the disease was more widespread. (encyclopedia.com)
The main problem with TB Infection is that it can become TB Disease at any time. (bccdc.ca)
Most people with TB Infection will never develop TB Disease. (bccdc.ca)
A chest X-ray can help identify any structural abnormalities or diseases (such as infection) that can cause or aggravate breathing problems. (mayoclinic.org)

The issue of infectious (communicable) disease in the fire service has been well established as a very serious concern. (iaff.org)
In the U.S., 27 states have made infectious diseases a presumptive illness for fire fighters and emergency medical providers. (iaff.org)
This webpage offers basic information about common infectious diseases that can affect the health and safety of IAFF members and their family members. (iaff.org)
Infectious disease is an area of rapidly changing conditions. (iaff.org)
The issue of infectious (communicable) disease in the fire service continues to take on an urgent meaning with fire fighter's risks of contracting AIDS, hepatitis, pertussis and MRSA. (iaff.org)
This program is intended to support the provisions of the IAFF Executive Board policy on infectious diseases. (iaff.org)
The policy has been updated by the IAFF due to current concern regarding the risk of transmission of HIV, hepatitis C, and other infectious diseases to emergency response personnel. (iaff.org)
The fire department physician must evaluate fire fighter, EMT and paramedic job duties to determine job limitations, if any, in the event of an individual's contraction of an infectious disease. (iaff.org)
Infectious diseases of the lung may damage areas of the lung tissue and contribute to chronic obstructive pulmonary disease. (medicinenet.com)
The core services team provides cell culture, hematology, hemostasis, clinical chemistry, microbiology, and molecular virology support for infectious disease studies at the IRF-Frederick. (nih.gov)
Professor Paul Ananth Tambyah, Professor of Medicine at the National University of Singapore and Senior Consultant Infectious Diseases Physician at the National University Hospital, Singapore. (imperial.ac.uk)

A normal Gram stain of sputum contains polymorphonuclear leukocytes, alveolar macrophages, and a few squamous epithelial cells. (medscape.com)
The quality of sputum samples is determined by the minimum number of squamous epithelial cells and polymorphonuclear leukocytes per low power field. (medscape.com)

The Burden of Pulmonary Nontuberculous Mycobacterial Disease in the United States. (copdfoundation.org)
The mycobacterial PNA-FISH assay was successfully adapted to human sputum demonstrating its potential for clinical diagnostic applications in addition to industrial MWF monitoring, to assess MWF-associated exposures and pseudo-outbreaks. (cdc.gov)

A sputum Gram stain is a laboratory test used to detect bacteria in a sputum sample. (mountsinai.org)
If someone has TB bacteria in their body and their body can't fight it, then it becomes TB Disease. (bccdc.ca)
The active bacteria begin to multiply in the body and cause TB disease. (tn.gov)
Some people develop TB disease soon after becoming infected, before their immune system can fight the TB bacteria. (tn.gov)
The most common pathogens detected with a sputum culture are bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, and Klebsiella species . (medscape.com)

Exacerbations of chronic obstructive pulmonary disease contribute to the high mortality rate associated with the disease. (aafp.org)
An improvement in asthma control, a decrease in hospitalizations, and a decrease in exacerbations were noted in those patients in whom sputum-guided therapy was used. (medscape.com)

Less common symp- more than 10,000 cumulative cases in the past two toms include sputum production, headache, haemopty- decades with mortality rates of 10% for SARS-CoV sis, sore throat, chest pain, and diarrhea(2). (who.int)

For example, when DL CO is below 75% of the predicted value, it indicates a problem that may impair exercise and affect long-term survival from lung diseases and disorders. (aidsmap.com)

A voluntary network of laboratories that submit test data to the CDC will provide valuable information as another early indicator of spread, along with other respiratory diseases (eg, influenza, RSV). (medscape.com)
GLA can shape immune responses and interfere with the course of respiratory diseases. (frontiersin.org)
In this review, we aim to analyze how the lung and gut microbiota influence each other and may impact on respiratory diseases. (frontiersin.org)
Viruses are also known to be key players in numerous respiratory diseases and to interact with the human immune system, but technical issues still limit the amount of data regarding virobiota ( Mitchell and Glanville, 2018 ). (frontiersin.org)
While GLA mycobiota also influences chronic gut diseases such as IBD, we will not address this key role in the present review: we aimed at analyzing how lung and gut bacteriobiota and mycobiota influence each other, how they interact with the human immune system, and their role in respiratory diseases. (frontiersin.org)
There are several categories of human disease models to study respiratory diseases and drug development: cell lines, primary cells, 3D cell models, cell co-cultures, explants and in silico models [ 4 ]. (karger.com)

Sputum-culture conversion (i.e., conversion from positive to negative culture result) is considered the principal prognostic indicator for treatment response and is often used as a surrogate endpoint in early-phase randomized clinical trials ( 12 , 13 ). (cdc.gov)
Epidemiological, clinical, and laboratory characteristics and treatment and outcomes data were obtained through data collection forms from electronic medical records, and the relation between clinical data and disease severity was analysed. (bmj.com)

But if you're coughing up blood with little or no sputum, seek immediate medical attention. (healthline.com)
Coughing up sputum the whole night through? (themedguru.com)

Overview of Rickettsial and Related Infections Rickettsial diseases (rickettsioses) and related diseases (anaplasmosis, ehrlichiosis, Q fever, scrub typhus) are caused by a group of gram-negative, obligately intracellular coccobacilli. (msdmanuals.com)

Sputum eosinophils. (mayoclinic.org)

Sputum samples have been used to quantify the degree of airway inflammation in human diseases such as asthma. (wikipedia.org)

Disease severity and timing of imaging appear to impact the rates of normal baseline imaging. (who.int)

How is mild coronavirus disease 2019 (COVID-19) managed? (medscape.com)
Illness caused by SARS-CoV-2 was termed COVID-19 by the WHO, the acronym derived from "coronavirus disease 2019. (medscape.com)

The sputum color of patients with acute cough and no underlying chronic lung disease does not imply therapeutic consequences such as prescription of antibiotics. (wikipedia.org)

But methods may be available to help prevent some cases of blood-tinged sputum. (healthline.com)
Our goal was to try to close this gap by tackling common challenges that patients and physicians face with traditional sputum collection methods. (copdfoundation.org)

Patients referred for assessment for TB, whose initial sputum was Xpert MTB positive, were recruited and their sputum specimens were pooled for analysis with sputum specimens that were Xpert MTB negative. (biomedcentral.com)

If there is any blood in the sputum, this should also be on the swab. (wikipedia.org)
Pink sputum - it indicates sputum evenly mixed with blood from alveoli and/or small peripheral bronchi as is seen in potential pulmonary edema. (wikipedia.org)
What Causes Blood-Tinged Sputum, and How Is It Treated? (healthline.com)
Blood-tinged sputum is a relatively common occurrence and isn't typically cause for immediate concern. (healthline.com)
Sometimes sputum can have visible streaks of blood in it. (healthline.com)
Lower respiratory infections and inhaling a foreign object are the likely causes of blood-tinged sputum in children. (healthline.com)
Treating blood-tinged sputum will require treating the underlying condition that's causing it. (healthline.com)
We investigated whether this pathway was activated in the sputum and blood of patients from the U-BIOPRED cohort. (ersjournals.com)
See your doctor if you have a cough that lingers for weeks, especially one that brings up sputum or blood, disturbs your sleep, or affects school or work. (mayoclinic.org)
It can lead to weight loss, chronic cough, fatigue and blood-streaked sputum . (pasteur.fr)
Overall, sputum specimens are observed for mucopurulent strands, leukocytes, and blood and culture results. (medscape.com)
Culture of the sputum on blood agar frequently reveals characteristic colonies, and identification is made by various serologic or biochemical tests. (medscape.com)

Induced sputum and other outcome measures in chronic obstructive pulmonary disease: safety and repeatability. (ox.ac.uk)
The primary cause of chronic obstructive pulmonary disease is cigarette smoking or exposure to tobacco smoke. (medicinenet.com)
It is estimated that 90% of the risk of developing chronic obstructive pulmonary disease is related to smoking tobacco and secondhand smoke (tobacco smoke exhaled by a smoker and then breathed in by a non-smoker). (medicinenet.com)
People who smoke tobacco are at the highest risk of developing chronic obstructive pulmonary disease. (medicinenet.com)
In general, three other non-genetic problems related to lung tissue play a role in chronic obstructive pulmonary disease. (medicinenet.com)

If you still do not produce enough sputum, you might have a procedure called bronchoscopy . (mountsinai.org)

In medicine, sputum samples are usually used for a naked eye examination, microbiological investigation of respiratory infections and cytological investigations of respiratory systems. (wikipedia.org)
Currently, an estimated 180,000 people in the U.S. suffer from NTM lung disease with the number of infections increasing by around 8% each year 1 . (copdfoundation.org)

4 The American Thoracic Society (ATS) and European Respiratory Society (ERS) define an exacerbation as an acute change in a patient's baseline dyspnea, cough, or sputum that is beyond normal variability, and that is sufficient to warrant a change in therapy. (aafp.org)
Q fever is an acute or chronic disease caused by the rickettsial-like bacillus Coxiella burnetii . (msdmanuals.com)
Acute disease causes a febrile illness that often affects the respiratory system, although sometimes the liver is involved. (msdmanuals.com)
Unlike rickettsial diseases, acute Q fever does not cause a rash. (msdmanuals.com)

Some people with asthma have more than one lung disease. (asthma.org.au)
In assessing asthma control, the British Thoracic Society recommends using sputum eosinophilia determinations to guide therapy. (medscape.com)

Sputum induction was performed on 122 occasions and was successful resulting in a cytospin adequate to assess a differential cell count in 95% of inductions. (ox.ac.uk)

Time to sputum-culture conversion was defined as time between treatment start date and date of first consistently culture-negative sputum. (cdc.gov)
Patients with NSCLC require a complete staging workup to evaluate the extent of disease, because stage plays a major role in determining the choice of treatment. (medscape.com)
He tested coinfection, and one tested negative by sputum smear positive for COVID-19 and was transferred to the National during admission but was later confirmed by culture to Isolation Centre for treatment. (who.int)

Oral corticosteroids are likely beneficial, especially for patients with purulent sputum. (aafp.org)

Centers for Disease Control and Prevention. (cdc.gov)
DTBE) of the Centers for Disease Control and Prevention (CDC). (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
The US Centers for Disease Control and Prevention (CDC) surveillance data from Houston and Atlanta suggest an incidence of 1 case per 100,000 persons per year. (medscape.com)

That's all the more reason for everyone to take seriously diseases like COVID-19 and do all we can to protect ourselves and others by stopping the spread. (bestcare.org)
The rate increased in 2020 to 82/100 000 despite a consequence of disruptions to health-care services the disruption to health-care services caused by the due to the coronavirus disease (COVID-19) pandemic, COVID-19 pandemic. (who.int)

Purulent sputum is typically yellow or green. (wikipedia.org)

Similar disease occasionally results from the closely related mycobacteria, M. bovis , M. africanum , and M. microti . (merckmanuals.com)

Modifiable with information on whether upper or lower disease control activities, and to work with reference respiratory material is better for coronavirus detection. (who.int)
Measurement of the intracellular pH is particularly crucial for the detection of numerous diseases, such as carcinomas, that are characterised by a low intracellular pH. (bvsalud.org)
FIND) has partnered with Cepheid, Inc. (Sunnyvale, CA) and the University of Medicine and Dentistry of New Jersey (UMDNJ, Newark, NY) to develop a TB-specific automated, cartridge-based nucleic amplification assay (Xpert MTB/RIF) based on the GeneXpert multi-disease platform, currently unique in its simplification of molecular testing with fully integrated and automated sample preparation, amplification and detection required for real-time polymerase chain reaction. (bvsalud.org)

Anatomy2

Organisms2

Diseases15

Chemicals and Drugs5

Analytical, Diagnostic and Therapeutic Techniques and Equipment15

Psychiatry and Psychology1

Phenomena and Processes6

Disciplines and Occupations1

Information Science1

Health Care1

Tuberculosis22

Cough and sputum production5

COPD54

Mucus7

Symptoms14

Phlegm2

Diagnosis7

Lungs7

Mycobacterium5

Severe9

Microscopy4

Microbial2

Pneumonia3

Produce sputum2

Specimen4

Shortness1

Symptom2

Bronchitis4

Saliva2

Infection8

Infectious11

Squamous epithelial cells2

Mycobacterial2

Bacteria5

Exacerbations2

Chest1

Lung diseases1

Respiratory diseases6

Clinical2

Coughing2

Gram1

Eosinophils1

Airway inflammation1

Severity1

Coronavirus disease 20192

Patients with acute1

Methods2

Assessment1

Blood12

Pulmonary disease5

Bronchoscopy1

Infections2

Acute4

Asthma2

Induction1

Treatment3

Corticosteroids1

Centers for Diseas4

COVID2

Purulent1

Mycobacteria1

Detection3