• Robinson KA , Baughman W , Rothrock G , Barrett NL , Pass M , Lexau C , Epidemiology of invasive Streptococcus pneumoniae infections in the United States, 1995-1998: opportunities for prevention in the conjugate vaccine era. (cdc.gov)
  • Greene CM , Kyaw MH , Ray SM , Schaffner W , Lynfield R , Barrett NL , Preventability of invasive pneumococcal disease and assessment of current polysaccharide vaccine recommendations for adults: United States, 2001-2003. (cdc.gov)
  • Black S , Shinefield H , Fireman B , Lewis E , Ray P , Hansen JR , Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. (cdc.gov)
  • Policy statement: recommendations for the prevention of pneumococcal infections, including the use of pneumococcal conjugate caccine (Prevnar), pneumococcal polysaccharide vaccine, and antibiotic prophylaxis. (cdc.gov)
  • Updated recommendations on the use of pneumococcal conjugate vaccine in a setting of vaccine shortage-Advisory Committee on Immunization Practices. (cdc.gov)
  • Updated recommendations on the use of pneumococcal conjugate vaccine: suspension of recommendation for third and fourth dose. (cdc.gov)
  • Whitney CG , Pilishvili T , Farley MM , Schaffner W , Craig AS , Lynfield R , Effectiveness of seven-valent pneumococcal conjugate vaccine against invasive pneumococcal disease: a matched case-control study. (cdc.gov)
  • Pneumococcal polysaccharide vaccine (PPSV23) mococcal vaccine called PCV13, are recommended can prevent pneumococcal disease . (cdc.gov)
  • Pneumococcal bacteria the vaccine before they turned 65. (cdc.gov)
  • This report updates the last recommendations by the Advisory Committee on Immunization Practices (ACIP) concerning pneumococcal polysaccharide vaccine (MMWR 1989;38:64-8,73-6). (cdc.gov)
  • This report contains updated information regarding a) antimicrobial resistance among pneumococci, b) vaccine effectiveness and cost-effectiveness, c) indications for vaccination, d) guidelines for revaccination, e) strategies for improving delivery of vaccine, and f) development of pneumococcal conjugate vaccine. (cdc.gov)
  • The focus of this report is the prevention of invasive pneumococcal disease (i.e., bacteremia, meningitis, or infection of other normally sterile sites) through the use of pneumococcal polysaccharide vaccine. (cdc.gov)
  • This vaccine protects against invasive bacteremic disease, although existing data suggest that it is less effective in protecting against other types of pneumococcal infections. (cdc.gov)
  • Pneumococcal conjugate vaccines are relatively new type of vaccine that has been shown to be highly effective at preventing disease and in stopping people from acquiring the bacteria in their noses and throats. (cdc.gov)
  • The vaccine used in Israel and the one we use in the United States protects against 13 different serotypes, and these cause most disease, but there are more than 90 serotypes all together. (cdc.gov)
  • The manuscript we are discussing here talks about how surveillance for pneumococcal infections in Israel found that the new vaccine program was preventing a lot of disease, but they also detected an increase in one of the strains that the vaccine doesn't cover-- serotype 12F. (cdc.gov)
  • The authors of this report were able to look at how the amount of invasive disease changed after a new pneumococcal conjugate vaccine program began in Israel. (cdc.gov)
  • The authors found that rates of pneumococcal disease did drop after the new vaccine program began. (cdc.gov)
  • Overall, disease rates dropped by about a third, and rates among the youngest kids, the target age group for the vaccine, dropped by about 50 percent. (cdc.gov)
  • While overall the vaccine program benefits were great, the investigators did detect a small but significant increase in disease caused by nonvaccine serotypes, especially serotype 12F. (cdc.gov)
  • Before 2021, ACIP recommended 23-valent pneumococcal polysaccharide vaccine (PPSV23) alone (up to 2 doses), or both a single dose of 13-valent pneumococcal conjugate vaccine (PCV13) in combination with 1-3 doses of PPSV23 in series (PCV13 followed by PPSV23), for use in U.S. adults depending on age and underlying risk for pneumococcal disease. (cdc.gov)
  • In addition, ACIP recommends use of either a single dose of PCV20 or ≥1 dose of PPSV23 for adults who have started their pneumococcal vaccine series with PCV13 but have not received all recommended PPSV23 doses. (cdc.gov)
  • During 2018-2019, approximately 60%-75% of all IPD in adults was caused by the 24 pneumococcal serotypes that were included in the formulations of commercially available polysaccharide conjugate vaccine (PCV) or pneumococcal polysaccharide vaccine (PPSV) vaccines (i.e. (cdc.gov)
  • The pneumococcal conjugate vaccine protects against 13 forms of pneumococcal bacterial infection. (chicagotribune.com)
  • A different vaccine, PPSV23 (brand name Pneumovax), protects against 23 types of the bacteria and is intended for all adults 65 years or older and children two years or older at higher risk of pneumococcal bacterial infection. (chicagotribune.com)
  • A meningitis vaccine is only recommended for children 2 months to 10 years old identified as having an increased risk of meningitis infection. (chicagotribune.com)
  • KENILWORTH, N.J.--(BUSINESS WIRE)-- Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended the approval of VAXNEUVANCE™ (Pneumococcal 15-valent Conjugate Vaccine) for active immunization for the prevention of invasive disease and pneumonia caused by Streptococcus pneumoniae in individuals 18 years of age and older. (merck.com)
  • VAXNEUVANCE is indicated in the U.S. for active immunization of adults 18 years of age and older for the prevention of invasive disease caused by the S. pneumoniae serotypes contained in the vaccine. (merck.com)
  • This combined, single jab vaccine contains your child's fourth dose of protection against haemophilus influenzae type b (received in the 6-in-1 vaccine at 8, 12 and 16 weeks old), and first dose to protect against meningitis C. Both infections are serious and can cause meningitis and blood poisoning (septicaemia), which can occasionally prove fatal. (netmums.com)
  • The Hib/MenC vaccine does not contain any live organisms and is therefore very safe for your baby, with no risk of them catching the diseases it protects against. (netmums.com)
  • The MenB vaccine protects against a potential meningococcal infection caused by meningococcal group B bacteria. (netmums.com)
  • Get a pneumococcal vaccine if you are aged 65 years or older. (drugs.com)
  • The pneumococcal conjugate vaccine (PCV13) and the pneumococcal polysaccharide vaccine (PPSV23) protect against pneumococcal infections. (kidshealth.org)
  • This vaccine may also be recommended after the age of 2 for children with certain health conditions (e.g., asthma, diabetes or another chronic disease). (uniprix.com)
  • Immunization prevents most childhood diseases, but there are some for which a vaccine doesn't exist. (uniprix.com)
  • Areas of medical therapeutics applicable to this work include pneumococcal vaccine design, intervention in gram-positive sepsis/meningitis, new antibiotic development strategies, and interruption of the spread of genetic elements responsible for antibiotic resistance. (stjude.org)
  • This replaced PCV 7 (Prevenar 7) the pneumococcal conjugate vaccine introduced into the routine childhood immunisation programme in September 2008. (hse.ie)
  • Pneumococcal conjugate vaccines reduce the rates of nasopharyngeal colonisation by vaccine serotypes, thus decreasing the potential for transmission from vaccinated to unvaccinated persons. (hse.ie)
  • The 23-valent pneumococcal polysaccharide vaccine (PPV23) has been recommended to risk-groups and adults aged ≥65 years since 1996. (biomedcentral.com)
  • The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in the childhood immunization program in July 2006, and was replaced by the 13-valent vaccine (PCV13) in 2011. (biomedcentral.com)
  • Children should get three doses of the pneumococcal conjugate vaccine when they are two, four and 12 months old. (hnhu.org)
  • Pneumococcal vaccine (Prevnara) is given by injection. (hnhu.org)
  • Who should NOT get the pneumococcal vaccine? (hnhu.org)
  • Persons who have had an allergic reaction to a previous pneumococcal vaccine. (hnhu.org)
  • The best way to prevent the infection is with a vaccine. (aultcare.com)
  • The pneumococcal vaccine is a shot that helps protect against some of the many types of pneumococcal bacteria. (aultcare.com)
  • This vaccine protects against 13 types of pneumococcal bacteria that commonly cause severe illness in children. (aultcare.com)
  • Pneumococcal polysaccharide vaccine (PPSV23). (aultcare.com)
  • This vaccine protects against 23 types of pneumococcal bacteria. (aultcare.com)
  • Strains of the pneumococcal bacteria (germs) are beginning to show increasing resistance to antibiotics emphasizing the importance of vaccine protection against pneumococcal disease. (ihs.gov)
  • A simple vaccine can minimize your chances to develop certain diseases such as shingles and pneumococcal infections. (uniprix.com)
  • Who Needs the Pneumococcal Vaccine? (total-health-care.com)
  • The pneumococcal vaccine is a vital preventive measure that can protect individuals from these potentially life-threatening diseases. (total-health-care.com)
  • In this article, we will explore who needs the pneumococcal vaccine and why it is crucial for certain populations. (total-health-care.com)
  • The pneumococcal vaccine plays a critical role in protecting individuals, particularly those who are more susceptible to pneumococcal diseases. (total-health-care.com)
  • By receiving the pneumococcal vaccine, these vulnerable populations can significantly reduce their risk of developing pneumonia. (total-health-care.com)
  • The pneumococcal vaccine helps prevent pneumonia by providing immunity against the most common strains of pneumococcus. (total-health-care.com)
  • The pneumococcal vaccine is especially important for infants and young children, as they are more susceptible to severe forms of pneumonia. (total-health-care.com)
  • The pneumococcal vaccine can provide them with an added layer of protection against pneumococcal infections and potentially life-threatening complications. (total-health-care.com)
  • The pneumococcal vaccine helps protect individuals from pneumococcal meningitis by stimulating the immune system to produce antibodies against the bacterium. (total-health-care.com)
  • By ensuring that infants receive the recommended doses of the pneumococcal vaccine, parents can significantly reduce the risk of their child developing this life-threatening infection. (total-health-care.com)
  • The pneumococcal vaccine helps prevent bloodstream infections by strengthening the immune system's ability to recognize and fight off the pneumococcus bacterium. (total-health-care.com)
  • By receiving the pneumococcal vaccine, these individuals can protect themselves from the potential complications of bloodstream infections and improve their overall health outcomes. (total-health-care.com)
  • Vaccine errors threaten to undermine the protection immunizations provide and often leave patients inadequately protected against serious diseases such as hepatitis A and B, pertussis, diphtheria, cervical cancer, and many others. (ismp.org)
  • Pfizer Inc., a U.S.-based multinational pharmaceutical corporation, recently revealed (September 2019) that it has made headways in phase II study on its 20-valent pneumococcal conjugate vaccine. (medgadget.com)
  • The company is developing its pneumococcal vaccine for treating invasive diseases and otitis media in healthy infant populations. (medgadget.com)
  • The candidate, the company found similar safety profile, as its Prevnar 13, a 13-valent pneumococcal conjugate vaccine. (medgadget.com)
  • A case in point is Merck developing 15-valent pneumococcal conjugate vaccine candidate, V114. (medgadget.com)
  • Particularly, progress made in development of vaccines for the development of invasive pneumococcal diseases has also reinforced lucrative avenues to vaccine manufacturers. (medgadget.com)
  • Pneumococcal polysaccharide vaccine is the only currently available preventive measure. (nationalacademies.org)
  • HONG KONG SAR - Media OutReach - 10 September 2023 - Recent findings from a comprehensive survey conducted in Hong Kong have revealed an alarming lack of awareness about the pneumococcal vaccine, leaving more than half of the city's middle-aged and elderly population unprotected against this potentially deadly infection. (yahoo.com)
  • CDC recommends all adults 19 through 64 years old with asthma get the pneumococcal polysaccharide vaccine. (infectioncontroltoday.com)
  • CDC's National Institute for Occupational Safety and Health (NIOSH) researchers found that adults with work-related asthma were more likely to have reported receiving a pneumococcal vaccine than adults with non-work-related asthma - 54 percent compared with 35 percent, respectively. (infectioncontroltoday.com)
  • Among adults with work-related asthma, pneumococcal vaccine coverage was lowest among Hispanics (36 percent), those without health insurance (39 percent), and adults ages 18 to 44 years (42 percent). (infectioncontroltoday.com)
  • People with work-related asthma are particularly vulnerable to pneumococcal pneumonia," said NIOSH director John Howard, MD. "Vaccination is the best way to prevent pneumococcal disease, including pneumonia, and CDC recommends that all adults with asthma, whether work-related or not, get the pneumococcal polysaccharide vaccine. (infectioncontroltoday.com)
  • To increase the number of adults with asthma who are vaccinated against pneumococcal disease, we recommend that healthcare providers verify if their patients who have asthma have received a pneumococcal vaccine and offer the vaccine to those not vaccinated. (infectioncontroltoday.com)
  • Children previously vaccinated with any pneumococcal vaccine or participants in previous studies with the VCN7-T vaccine candidate. (who.int)
  • it is now included in the 13-, 15-, and 20-valent pneumococcal conjugate vaccines. (msdmanuals.com)
  • Additional infection-causing serotypes have been included in the updated 15- and 20-valent pneumococcal conjugate vaccines. (msdmanuals.com)
  • First let me tell you a little about pneumococcal conjugate vaccines and pneumococcal disease. (cdc.gov)
  • Pneumococcal conjugate vaccines are now used in infant vaccination programs in most countries around the world. (cdc.gov)
  • Pneumococcal conjugate vaccines are very specific for preventing certain strains. (cdc.gov)
  • Vaccines are one of the most important ways to prevent children from getting some life-threatening diseases. (who.int)
  • Getting pneumococcal vaccines as recommended reduces your chance of contracting and dying from pneumococcal disease. (nfid.org)
  • Two types of pneumococcal vaccines (conjugate and polysaccharide) are available in the US. (nfid.org)
  • This report compiles and summarizes all published recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) for use of pneumococcal vaccines in adults aged ≥19 years in the United States. (cdc.gov)
  • In 2021, two new pneumococcal conjugate vaccines (PCVs), a 15-valent and a 20-valent PCV (PCV15 and PCV20), were licensed for use in U.S. adults aged ≥18 years by the Food and Drug Administration. (cdc.gov)
  • Current pneumococcal vaccines use the pneumococcal capsular polysaccharides as antigens to generate serotype-specific antibodies, which facilitate serotype-specific clearance of pneumococci through opsonophagocytosis ( 4 ). (cdc.gov)
  • For more than 100 years, Merck has contributed to the discovery and development of novel medicines and vaccines to combat infectious diseases. (merck.com)
  • For over 130 years, Merck, known as MSD outside of the United States and Canada, has been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases in pursuit of our mission to save and improve lives. (merck.com)
  • Vaccines help prevent against certain diseases caused by bacteria or viruses. (drugs.com)
  • These vaccines prevent infections in children who get them, and help stop the infections from spreading to others. (kidshealth.org)
  • These vaccines are very effective at preventing severe disease, hospitalization, and even death. (kidshealth.org)
  • The pneumococcal vaccines contain only a small piece of the germ and so cannot cause pneumococcal disease. (kidshealth.org)
  • Children receive a number of vaccines starting at a young age to protect them against common childhood diseases. (uniprix.com)
  • Which pneumococcal vaccines are recommended in Ireland? (hse.ie)
  • Vaccines are crucial for long-term and sometimes lifelong protection against preventable diseases. (uniprix.com)
  • Unconjugated as well as conjugated pneumococcal polysaccharide vaccines have been used with success for reducing the rate of pneumococcal infections, especially in adults and children. (medgadget.com)
  • Over the past few years, several pharmaceutical and biopharmaceuticals have enrolled themselves in evaluating candidates of developing pneumococcal conjugate vaccines. (medgadget.com)
  • The high risk of mortality of invasive pneumococcal diseases has spurred research pertaining to this patient cohort, thereby unlocking new prospects in the pneumonia vaccines market. (medgadget.com)
  • This aside, increasing trend of antibiotic resistance has spurred research in pneumococcal vaccines that can cover against wide range of pneumococci antigens. (medgadget.com)
  • However, some aspects of the relationship between celiac disease (CD) and vaccines are still unclear. (mdpi.com)
  • As the next generation of pneumococcal vaccines with broader serotype coverage becomes accessible in Hong Kong, international vaccination guidelines, including those from the United States Centers for Disease Control and Prevention (CDC), have been updated to encompass the latest immunization recommendations. (yahoo.com)
  • Travelers 60 years and older should also get vaccines to protect against shingles and pneumococcal diseases, which cause infections in the lungs, blood, brain, and ears. (educationupdate.com)
  • Pneumococcal vaccines help protect against some of the more than 90 types of pneumococcal bacteria. (infectioncontroltoday.com)
  • yet, the number of people who plan on getting the vaccines for each of the infections remains low, according to the NFID announcement today. (infectioncontroltoday.com)
  • Most vaccines that are part of the Swedish child vaccination programme are given as combination vaccines, i.e. vaccines against several diseases are given in the same shot in order to minimize the number of injections. (folkhalsomyndigheten.se)
  • Talk to your healthcare professional about pneumococcal vaccination. (nfid.org)
  • The following diseases and their associated vaccination information can serve as an introductory guide for parents and adults seeking information on hearing loss and certain diseases. (chicagotribune.com)
  • The booster is highly effective and rates of the infections in the UK are now at their lowest ever, as a result of vaccination. (netmums.com)
  • Vaccination isn't mandatory but is strongly recommended by health care professionals to help children avoid diseases that can be very serious and even fatal. (uniprix.com)
  • Prevention of disease through vaccination is now more important than ever. (hse.ie)
  • Coverage by 7-valent pneumococcal conjugate vaccination (PCV7) increased since 2002, while little variation occurred in other potentially associated risk factors. (bmj.com)
  • Vaccination is the most effective way to prevent pneumococcal meningitis and its devastating consequences. (total-health-care.com)
  • Vaccination is particularly important for infants, as they are at a higher risk of developing pneumococcal meningitis. (total-health-care.com)
  • By reducing the risk of pneumococcal bacteremia, vaccination can significantly lower the chances of developing sepsis and its life-threatening consequences. (total-health-care.com)
  • The Centers for Disease Control and Prevention (CDC) provides recommendations regarding pneumococcal vaccination for different age groups and high-risk individuals. (total-health-care.com)
  • While none of the reported errors caused immediate harm to a patient, absent or improper vaccination may have detrimental effects on individual and public health, leading to disease outbreaks, loss of herd immunity that may propagate an epidemic, costly overvaccination and re-vaccination, and consumer skepticism or refusal of vaccination. (ismp.org)
  • Despite the established effectiveness of vaccination as a preventative measure against pneumococcal disease, the city's current vaccination rate is unsatisfactory. (yahoo.com)
  • Although the majority of people know that vaccination is an effective way to prevent pneumococcal infection, about half of the respondents have not been vaccinated. (yahoo.com)
  • On the hand, about half of the people do not know where to get the pneumococcal vaccination, and they are unaware that individuals aged 65 or above are eligible to receive subsided or even free government vaccination services. (yahoo.com)
  • The Advisory Committee on Immunization Practices recommends a pneumococcal polysaccharide vaccination for all adults 19 through 64 years old with asthma. (infectioncontroltoday.com)
  • Our study found that the vaccination coverage for pneumococcal disease among adults who have ever worked and have asthma falls short of achieving the coverage public health experts recommend," said Katelynn Dodd, MPH, lead author and an epidemiologist in the Respiratory Health Division, NIOSH. (infectioncontroltoday.com)
  • Vaccination is the safest, most effective way to protect yourself from getting pneumococcal disease. (infectioncontroltoday.com)
  • Our aim was to evaluate the immunogenicity of pneumococcal and influenza vaccination in patients with IBD receiving different treatment. (ecco-ibd.eu)
  • We searched four databases for studies evaluating seroprotection and seroconversion rates after influenza or pneumococcal vaccination in IBD. (ecco-ibd.eu)
  • Second moment: hospital surveillance, for the entire pediatric population in the Cienfuegos province, of invasive pneumococcal diseases (IPD), pneumococcal pneumonia and acute otitis media (AOM) from the year after the vaccination campaign ended. (who.int)
  • In Sweden, children are offered protection against eleven diseases through the national vaccination programme for children. (folkhalsomyndigheten.se)
  • In 2022, a vaccination programme against pneumococcal infections for risk groups started. (folkhalsomyndigheten.se)
  • The vaccination programmes are governed by the Communicable Diseases Act and regulations issued by the Public Health Agency of Sweden. (folkhalsomyndigheten.se)
  • Starting in 2022, persons with certain underlying diseases will be offered vaccination against invasive pneumococcal infections within a national vaccination programme. (folkhalsomyndigheten.se)
  • Acute infections are treated with appropriate antibiotics and prevented also with vaccination (meningococcal, pneumococcal, and haemophilus). (lu.se)
  • Pneumococcal disease refers to any illness caused by pneumococcal bacteria. (cdc.gov)
  • PPSV23 protects against 23 types of bacteria that cause pneumococcal disease. (cdc.gov)
  • Severe pneumococcal infections result from dissemination of bacteria to the bloodstream and the central nervous system. (cdc.gov)
  • We used whole-transcriptome shotgun sequencing (RNA-seq) to compare the S. pneumoniae transcriptome in biofilms, bacteria dispersed from biofilms after exposure to IAV, febrile-range temperature, or ATP, and planktonic cells grown at 37°C. Compared with biofilm bacteria, actively dispersed S. pneumoniae, which were more virulent in invasive disease, upregulated genes involved in carbohydrate metabolism. (lu.se)
  • Oral and respiratory tract infections caused by bacteria such as Streptococcus pneumoniae and Klebsiella pneumoniae pose a particular threat because of the rise of antibiotic-resistant strains, with vulnerable patient populations at high risk of infection [ 2 , 3 ]. (springer.com)
  • More than half of middle ear infections are the result of pneumococcus bacteria, while severe forms of the disease can cause permanent hearing loss. (chicagotribune.com)
  • Meningitis is a potentially life-threatening infection of the brain and spinal cord caused by several different types of bacteria. (wmich.edu)
  • and increased risks for pneumonia infections related to pneumococcal bacteria when a person has celiac disease. (medicalnewstoday.com)
  • The global prevalence of pneumococcal disease, an infection caused by bacteria called Streptococcus pneumoniae , is evolving. (merck.com)
  • Pneumococcal disease is an infection caused by pneumococcal bacteria. (drugs.com)
  • The bacteria that cause these infections spread through person-to-person contact. (kidshealth.org)
  • PCV13 protects against 13 types of pneumococcal bacteria, which cause the most common pneumococcal (new-muh-KOK-uhl) infections in kids. (kidshealth.org)
  • One type of bacteria that can cause an infection is called Streptococcus pneumonia (or pneumococcus). (hnhu.org)
  • Four out of 10 healthy people have pneumococcal bacteria in their mouth, nose and throat without becoming ill. (hnhu.org)
  • When these bacteria enter the body they can cause pneumococcal pneumonia, which is an infection of the lungs. (hnhu.org)
  • These bacteria can attack the blood cells and cause a serious disease called bacteraemia. (hnhu.org)
  • Pneumoncoccal bacteria can also cause milder forms of pneumonia, sinus infections, and middle ear infections (otitis media) particularly in children. (hnhu.org)
  • Bacteremia (bloodstream infection) - Bacteremia is an illness caused when bacteria get into the blood. (hnhu.org)
  • Children who get pneumonia from the pneumococcal bacteria will have a fever and cough that may bring up thick mucous. (hnhu.org)
  • Many different bacteria can cause ear infections, including pneumococcus. (hnhu.org)
  • Pneumococcal infection is caused by the pneumococcus bacteria. (aultcare.com)
  • It is estimated that 400,000 to 5000,000 cases of pneumonia due to pneumococcal bacteria occur yearly in the USA with about a 5 percent to 10 percent fatality rate. (ihs.gov)
  • Persons 65 years of age and older who have bacteremia (bacteria in the blood) with a pneumococcal infection have a much higher risk of death. (ihs.gov)
  • At the present time there are 83 known pneumococcal bacteria strains. (ihs.gov)
  • The bacteria Streptococcus pneumoniae is responsible for pneumococcal infections causing otitis media, bacteremia, pneumonia, and meningitis. (medgadget.com)
  • However, it is also a cause of significant disease, being a leading cause of pneumonia, bacterial meningitis, and sepsis. (wikipedia.org)
  • Pneumococcal pneumonia represents 15%-50% of all episodes of community-acquired pneumonia, 30-50% of all cases of acute otitis media, and a significant proportion of bloodstream infections and bacterial meningitis. (wikipedia.org)
  • Each year in the United States, pneumococcal disease accounts for an estimated 3,000 cases of meningitis, 50,000 cases of bacteremia, 500,000 cases of pneumonia, and 7 million cases of otitis media (1-4). (cdc.gov)
  • The main diseases pneumococcus causes are mild infections, like ear and sinus infections, but pneumococcus can also cause severe illnesses like pneumonia and meningitis. (cdc.gov)
  • In the US, pneumococcal pneumonia, meningitis, and bloodstream infections (sepsis) kill tens of thousands each year, including thousands of adults age 65 years and older. (nfid.org)
  • Pneumococcal meningitis can be deadly. (nfid.org)
  • People who survive pneumococcal meningitis can suffer from devastating health problems like hearing loss, seizures, blindness, and paralysis. (nfid.org)
  • and meningitis (infection of the coverings of the brain and spinal cord), as well as non-invasive pneumonia (when pneumococcal disease is confined to the lungs). (merck.com)
  • A meningococcal infection can be very serious, causing meningitis and sepsis which can lead to severe brain damage, amputations and in some cases, death. (netmums.com)
  • Pneumococcal infections can lead to serious conditions including pneumonia, septicaemia , and meningitis . (netmums.com)
  • The infection may cause pneumonia, meningitis, or an ear infection. (drugs.com)
  • They can lead to serious infections like pneumonia , blood infections, and bacterial meningitis . (kidshealth.org)
  • Another 65 young children develop pneumococcal meningitis. (hnhu.org)
  • Meningitis (brain infection) - Meningitis is a serious disease of the covering of the brain and spinal cord. (hnhu.org)
  • This includes pneumonia, infection in the blood, and meningitis (infection of the tissues covering the brain and spinal cord). (aultcare.com)
  • In young children, pneumococcal infection often causes ear infections, which can lead to hearing loss, or rarely more serious complications, such as meningitis. (aultcare.com)
  • Pneumococcal infection is a leading cause of death worldwide and a major cause of pneumonia, meningitis and other Invasive (blood borne) diseases. (ihs.gov)
  • Protection Against Meningitis: Pneumococcal meningitis is a severe infection that affects the membranes surrounding the brain and spinal cord. (total-health-care.com)
  • Pneumococcal meningitis is a specific type of meningitis caused by the pneumococcus bacterium. (total-health-care.com)
  • 26 , 32 Although pneumococcal pneumonia does not result in permanent lung damage, complications from bacteremia and meningitis are common and can damage other organ systems. (nationalacademies.org)
  • Additionally, few people know that pneumococcus can also cause severe diseases such as meningitis and septicemia. (yahoo.com)
  • Cumulative incidence of disease cases (ENI, pneumonia and bacterial meningitis and Acute Otitis Media). (who.int)
  • Damage to the respiratory epithelium by chronic bronchitis or common respiratory viral infections, notably influenza, may predispose to pneumococcal invasion. (msdmanuals.com)
  • There is an association between pneumococcal pneumonia and influenza. (wikipedia.org)
  • Damage to the lining of the airways (respiratory epithelium) and upper respiratory system caused by influenza may facilitate pneumococcal entry and infection. (wikipedia.org)
  • During the spring of 2009, a novel influenza A (H1N1) virus of swine origin caused human infection and acute respiratory illness in Mexico. (who.int)
  • However, influenza A virus (IAV) infection releases virulent pneumococci from biofilms in vitro and in vivo. (lu.se)
  • Specifically, the Celiac Disease Center at Columbia University Medical Center report increased risks for worse outcomes with influenza infection. (medicalnewstoday.com)
  • Pneumonia related to influenza and pneumococcal infection is one of the most common infection-related complication in IBD. (ecco-ibd.eu)
  • The Infectious Diseases Society of America. (cdc.gov)
  • This website is designed to provide education to the public and healthcare professionals about infectious diseases across the lifespan. (nfid.org)
  • To learn more about Merck's infectious diseases pipeline, visit www.merck.com . (merck.com)
  • Today, Merck continues to be at the forefront of research to prevent and treat diseases that threaten people and animals - including cancer, infectious diseases such as HIV and Ebola, and emerging animal diseases - as we aspire to be the premier research-intensive biopharmaceutical company in the world. (merck.com)
  • Community-acquired pneumonia (CAP) is one of the most common infectious diseases and an important cause of mortality and morbidity worldwide. (medscape.com)
  • T here appears to be a direct relationship between increasing age and susceptibility to infections, although the documentation is weak for many specific infectious diseases. (nationalacademies.org)
  • 18 Undoubtedly, there are other infectious diseases that present risks for the elderly, but limited data preclude their identification at this time. (nationalacademies.org)
  • All the talks from the 9th Annual Edinburgh Infectious Diseases Symposium are now available to watch again. (ed.ac.uk)
  • The Ker Memorial Lecture is given annually by an eminent infectious disease researcher, and the The Memorial Prize is awarded each year for the best PhD thesis submitted to the University of Edinburgh in infectious diseases. (ed.ac.uk)
  • Both prizes are made possible by the generous gift of Miss Aileen Ker (pronounced 'car') in memory of her father and grandfather, Drs Frank and Claude Ker, who were influential infectious diseases clinicians, practising in Edinburgh during the first half of the 20th century. (ed.ac.uk)
  • Dr. Claude Buchanan Ker (1867-1925) spent his professional medical career in Edinburgh, working ceaselessly to improving the treatment of infectious diseases. (ed.ac.uk)
  • After PCV7 licensure, pneumococcal infection rates in children aged 5+ with sickle cell disease significantly decreased. (medindia.net)
  • The decrease in this age group can largely be attributed to a 98% decline in Invasive pneumococcal disease (IPD) due to serotypes covered by PCV7 between 2008 and 2016. (hse.ie)
  • citation needed] People with a compromised immune system, such as those living with HIV, are also at higher risk of pneumococcal disease. (wikipedia.org)
  • A decline of 50% in notifications of disease caused by the additional serotypes in PCV13 was also observed. (hse.ie)
  • With the inclusion of PCV13 in the National Immunization Program, continued monitoring of the prevailing serotypes of S. pneumoniae isolates in the Philippines is needed to guide disease and AMR control measures. (who.int)
  • Occasionally, if a person catches a virus or their health is off in some other way, pneumococcus can grow and spread and cause disease. (cdc.gov)
  • Invasive disease is a set of illnesses in which pneumococcus is grown from a specimen of blood or spinal fluid collected from a person who is ill. (cdc.gov)
  • Pneumococcus can colonize the upper respiratory tract, most commonly in young children, and is transmitted to others through contact with respiratory droplets from a person with pneumococcal colonization in the upper respiratory tract ( 1 ). (cdc.gov)
  • In adults, pneumococcal pneumonia is the most common type of pneumococcal disease, and pneumococcus is the most common bacterial cause of pneumonia that results in hospitalization ( 3 ). (cdc.gov)
  • The current study explores the toxin pneumolysin, which is produced by the pneumococcus and facilitates its disease-inducing effects. (scilifelab.se)
  • The vaccinations that are offered to all children protect against eleven diseases: rotavirus infection, diphtheria, tetanus, whooping cough, polio, infections caused by Haemophilus influenzae type b, measles, mumps, rubella, serious diseases caused by pneumococcus and human papillomavirus (HPV). (folkhalsomyndigheten.se)
  • 90 different pneumococcal serotypes have been identified based on their reaction with type-specific antisera. (msdmanuals.com)
  • Serotype 3 strains, which are more heavily encapsulated and tend to form more mucoid colonies than other serotypes, are common causes of invasive pneumococcal disease in adults. (msdmanuals.com)
  • These serotypes cause about 90% of invasive infections in children and 60% in adults. (msdmanuals.com)
  • The authors did this by analyzing information from case reports over time and by doing tests on the particular pneumococci causing these infections to see what serotypes they were. (cdc.gov)
  • At least 100 pneumococcal serotypes were documented as of 2020 ( 5 - 7 ). (cdc.gov)
  • To this end, they are including most common serotypes for preventing invasive pneumococcal diseases in paediatrics. (medgadget.com)
  • 2 Invasive pneumococcal in the Africa-Eastern Mediterranean region, whereas disease (IPD), defined as infection of normally sterile serotypes 1 and 14 were prevalent in Europe and Latin sites of the body with S. pneumoniae , most frequently America. (who.int)
  • Data are lacking on the prevailing pneumococcal axone and levofloxacin was done fol owing the method serotypes in the Philippines, including their resistance to described by the Clinical and Laboratory Standard Insti- specific antimicrobials. (who.int)
  • Although antibiotics are considered to be effective in the treatment of pneumococcal diseases, deaths and complications often occur despite the prompt use of effective antibiotics. (nationalacademies.org)
  • and c) upper respiratory tract infections, including otitis media and sinusitis. (cdc.gov)
  • It can also cause a wide variety of other infections including sinusitis, osteomyelitis, bronchitis and otitis media. (hse.ie)
  • Otitis media (middle ear infection) - When a person has a middle ear infection, the eardrum turns red, and the space behind it fills with fluid or pus. (hnhu.org)
  • Older adults, even those without other disease, tend to have a poor prognosis with pneumococcal infections. (msdmanuals.com)
  • All adults 65 years or older , Anyone 2 years or older with certain medical conditions that can lead to an increased risk for pneumococcal disease . (cdc.gov)
  • It's important to prevent pneumococcal disease in adults. (nfid.org)
  • An estimated 150,000 US adults are hospitalized with pneumococcal pneumonia each year. (nfid.org)
  • While healthy adults can suffer from pneumococcal disease, patient populations particularly vulnerable to infection include older adults such as those 65 years of age and older, people with HIV, and those with certain chronic health conditions. (merck.com)
  • Children younger than 2 years old, adults over 65, and people with some medical conditions are at high risk for serious pneumococcal infections. (kidshealth.org)
  • This report summarizes surveillance findings from NYCDOH's data for 1995, which indicate that the highest case rates were among children aged less than 4 years and that, among adults aged 20-44 years with PNSP infections, 71.4% also were infected with human immunodeficiency virus (HIV). (cdc.gov)
  • impetigo is a common bacterial infection of children's skin but is rarer in adults, and acne is a common infection of the skin of adolescents but is uncommon in childhood or in older adults. (britannica.com)
  • Mr. Chow Chun-man, Vice President of Hong Kong Respiratory Nursing College, concurred, noting that older adults are particularly susceptible to severe complications from pneumococcal disease. (yahoo.com)
  • Adults with asthma are at increased risk for pneumococcal disease, yet according to a new Centers for Disease Control and Prevention (CDC) study published today in the American Journal of Preventive Medicine , just 54 percent of adults with work-related asthma-asthma triggered by an exposure at work-have been vaccinated against the infection. (infectioncontroltoday.com)
  • Adults with asthma who get pneumococcal pneumonia are at risk for additional complications including asthma exacerbation and invasive pneumococcal disease. (infectioncontroltoday.com)
  • Invasive pneumococcal disease (IPD) and sepsis are responsible for substantial morbidity and mortality worldwide with about 2 million deaths each year [ 4 ]. (biomedcentral.com)
  • Diphtheria is a severe bacterial infection that causes a thick covering in the back of your mouth and throat. (drugs.com)
  • Epidemiological studies suggest that inhalation of toxins increases the risk of airway bacterial infection. (ersjournals.com)
  • In particular, the absence of a functional spleen, through congenital asplenia, surgical removal of the spleen, or sickle-cell disease predisposes one to a more severe course of infection (overwhelming post-splenectomy infection) and prevention measures are indicated. (wikipedia.org)
  • At-risk populations include individuals with diabetes, asthma, chronic obstructive pulmonary disease, human immunodeficiency virus (HIV), sickle cell disease, and cardiovascular diseases. (medgadget.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • Dr. Vik Kapil and I come to you from the Centers for Disease Control and Prevention, Agency for Toxic Substances and Disease Registry in Atlanta, Georgia. (cdc.gov)
  • Announcer] This program is presented by the Centers for Disease Control and Prevention. (cdc.gov)
  • Statistics from the US Centers for Disease Control and Prevention (CDC) suggest that about 49% of smokers develop chronic bronchitis and 24% develop emphysema / COPD . (medicinenet.com)
  • bacterium, which is a severe infection in the blood. (wmich.edu)
  • COVID-19 is a highly contagious disease that can cause severe and fatal acute respiratory symptoms. (medicalnewstoday.com)
  • Tetanus is a severe infection that may cause painful muscle spasms and lockjaw. (drugs.com)
  • Diseases that can cause severe liver damage can lead to ascites. (limamemorial.org)
  • Pneumonia is a respiratory infection that can lead to severe complications, such as respiratory failure and even death. (total-health-care.com)
  • 1. General public's knowledge of pneumococcal infection is limited, leading to oversight of the severe consequences it can bring. (yahoo.com)
  • The host factors driving those processes are not well defined, in part due to a lack of animal models that reproduce the transition from asymptomatic colonization to severe clinical disease. (lu.se)
  • Importantly, this model reproduces the susceptibility of aging, because compared to young mice, old mice display more severe clinical illness and succumb to disease more frequently. (lu.se)
  • PPSV23): What You Need to Know disponibles en español y en muchos otros idiomas. (cdc.gov)
  • People 65 years or older should get a dose of PPSV23 many types of illnesses, including pneumonia, which even if they have already gotten one or more doses of is an infection of the lungs. (cdc.gov)
  • Certain infections are important risk factors for the elderly because the illnesses they cause reduced quality of life during the infection and are at times fatal. (nationalacademies.org)
  • The costs of pneumococcal diseases are great because the elderly require hospitalization and the illnesses often cause complications. (nationalacademies.org)
  • With pandemic prevention measures relaxing, we're seeing a resurgence of serious illnesses linked to pneumococcal infections back to pre-epidemic levels. (yahoo.com)
  • citation needed] The risk of pneumococcal infection is much increased in persons with impaired IgG synthesis, impaired phagocytosis, or defective clearance of pneumococci. (wikipedia.org)
  • Our data suggest that disease is caused by pneumococci that are primed to move to tissue sites with altered nutrient availability and to protect themselves from the nasopharyngeal microflora and host immune response. (lu.se)
  • ISPPD is a biennial international symposium, which is the leading event for those interested in pneumococci and pneumococcal diseases, bringing together professionals in the field to raise global awareness and improve standards of diagnosis, prevention and treatment. (pharmiweb.com)
  • Since oxidative stress in airway cells increases platelet-activating factor receptor (PAFR) expression, and PAFR is co-opted by pneumococci to adhere to host cells, we hypothesised that E-cigarette vapour increases pneumococcal adhesion to airway cells. (ersjournals.com)
  • This paper describes a novel mouse model that recreates the transition of pneumococci from asymptomatic carriage to disease upon viral infection. (lu.se)
  • In this model, mice are first intranasally inoculated with biofilm-grown pneumococci to establish asymptomatic carriage, followed by IAV infection of both the nasopharynx and lungs. (lu.se)
  • Clinical signs and symptoms and physical examination findings alone cannot distinguish S pneumoniae disease from infections caused by other pathogens. (medscape.com)
  • S pneumoniae can cause a wide variety of clinical symptoms owing to its ability to cause disease by either direct extension from the nasopharynx into surrounding anatomic structures or vascular invasion with hematogenous spread. (medscape.com)
  • These virulence factors contribute to some of the clinical manifestations during infection with S. pneumoniae. (wikipedia.org)
  • These data help explain pneumococcal virulence after IAV infection and have important implications for studies of S. pneumoniae pathogenesis. (lu.se)
  • By separating carriage and disease into distinct steps and providing the opportunity to analyze the genetic variants of both the pathogen and the host, this S. pneumoniae/IAV co-infection model permits the detailed examination of the interactions of an important pathobiont with the host at different phases of disease progression. (lu.se)
  • Preventing pneumococcal disease among infants and young children: recommendations of the Advisory Committee on Immunization Practices (ACIP). (cdc.gov)
  • The Canadian Paediatric Society and the National Advisory Committee on Immunization strongly recommend routine immunization of infants and young children against pneumococcal disease. (hnhu.org)
  • It has pneumococcal surface proteins that inhibit complement-mediated opsonization, and it secretes IgA1 protease that will destroy secretory IgA produced by the body and mediates its attachment to respiratory mucosa. (wikipedia.org)
  • Since invasive pneumococcal strains adhere to, and translocate across, respiratory tract epithelial cells, adhesion is a prerequisite for establishing pneumococcal disease [ 4 ]. (ersjournals.com)
  • The phenomenon of natural immunity can be illustrated equally well with examples from the respiratory, intestinal, or genital tracts, where large surface areas are exposed to potentially infective agents and yet infection does not occur. (britannica.com)
  • These infections are highly contagious and may lead to serious, even life-threatening complications. (wmich.edu)
  • Currently, there is no research to indicate if those with celiac disease are at higher risk for developing COVID-19 or its complications. (medicalnewstoday.com)
  • It works by stimulating the immune system to produce antibodies against the bacterium, reducing the risk of infection and its associated complications. (total-health-care.com)
  • When you follow the immunization schedule to protect your child and watch out for symptoms of other common infections, you generally don't need to worry about childhood diseases. (uniprix.com)
  • Pneumococcal bloodstream infections can be deadly. (nfid.org)
  • In Canada, about 700 children under age five develop serious pneumococcal bacteraemia each year. (hnhu.org)
  • Each year in Canada, about 15 children under age five die from serious pneumococcal disease. (hnhu.org)
  • However, the NCA also state that those with celiac disease (especially active celiac disease, where a person experiences routine celiac disease symptoms) are more susceptible to infections. (medicalnewstoday.com)
  • This model can also serve as an important tool for identifying potential therapeutic targets against secondary pneumococcal pneumonia in susceptible hosts. (lu.se)
  • In addition, they did special DNA fingerprinting of the pneumococcal serotype 12F strains to see if the strains were related to each other genetically or to other serotype 12F strains around the globe. (cdc.gov)
  • And serotype12F is now the most common serotype causing disease in Israel. (cdc.gov)
  • GBS isolates from patients with invasive diseases during 2006 -2015 were investigated for capsular serotype, multilocus sequence type (ST), antimicrobial susceptibility, and resistance genes. (medworm.com)
  • The childhood PCV protects against 13 strains of the pneumococcal bacterium, providing excellent immunity for children. (netmums.com)
  • Most pneumococcal disease is due to a portion of these strains. (ihs.gov)
  • Are You at Risk for Pneumococcal Disease? (nfid.org)
  • Babies whose mothers become infected during pregnancy may be born with hearing loss, and children who contract it directly are at greater risk of ear infections that could result in hearing damage. (chicagotribune.com)
  • Abnormal cholesterol levels increase your risk for heart disease and stroke. (drugs.com)
  • Who is most at risk of pneumococcal disease? (hse.ie)
  • Older age and higher severity of disease were important risk factors for death in IPD. (biomedcentral.com)
  • 65 year age groups and in the older population, chronic comorbid disease is a risk factor for acquiring IPD [ 2 ]. (biomedcentral.com)
  • This is because the flu may increase your risk of getting pneumococcal disease. (aultcare.com)
  • Populations at high risk are the elderly, alcoholics, and individuals with immune disorders, certain blood diseases, and certain kidney disorders. (ihs.gov)
  • By scheduling your annual wellness visit with one of our Catholic Health primary care providers, we will address all your health concerns and establish clear health care goals to decrease your risk of developing many diseases. (issuu.com)
  • The environment of an elderly individual can also influence his or her exposure to infections, with long-term care facilities 28 and hospitals 47 bringing greater risk than living at home. (nationalacademies.org)
  • Pneumococcal disease has long been recognized as an important risk factor for the elderly. (nationalacademies.org)
  • The elderly, particularly those grappling with chronic diseases, are at a significant risk. (yahoo.com)
  • Patients with inflammatory bowel disease (IBD) have a high risk for infection. (ecco-ibd.eu)
  • S. lugdunensis , a coagulase-negative species, can cause invasive disease with virulence similar to that of S. aureus . (merckmanuals.com)
  • Pneumococcal disease can lead to significant morbidity and mortality, particularly amongst the very young, the very old, those with impaired immunity and those with anatomic or functional asplenia. (hse.ie)
  • Compte tenu du nombre croissant d'infections et de décès par le virus de la grippe pandémique (H1N1) 2009 confirmés en laboratoire dans la Région OMS de la Méditerranée orientale, le Bureau régional a convoqué une réunion consultative d'experts impliqués dans la prise en charge clinique de patients infectés par ce virus. (who.int)
  • A diet that emphasizes healthy foods rather than individual nutrients may help patients with chronic kidney disease live longer. (medindia.net)
  • During the 6 months preceding illness onset, 43 (34.4%) patients with invasive disease had been hospitalized, and 54 (43.2%) had received antibiotic therapy. (cdc.gov)
  • We carried out a prospective observational study of patients with IPD in Nord Trøndelag county in Norway from 1993 to 2011 to study the clinical variables and disease outcome. (biomedcentral.com)
  • Host factors such as diabetes, liver disease and COPD are associated with increased case fatality rate among immunocompetent patients. (biomedcentral.com)
  • However, important determinants of poor outcome of the disease remain to be identified to improve the management and treatment of IPD patients. (biomedcentral.com)
  • Many elderly patients hospitalized due to pneumococcal infections require intensive care and mechanical ventilation, with many suffering from significant sequelae, including reduced lung function, even after discharge,' he remarked. (yahoo.com)
  • Patients have frequent infections (pneumococcal pneumonia) and chronic inflammatory disease, including pulmonary fibrosis. (lu.se)
  • Further reductions in morbidity and mortality from pneumococcal diseases require that preventive measures be used. (nationalacademies.org)
  • This study suggests that E-cigarette vapour has the potential to increase susceptibility to pneumococcal infection. (ersjournals.com)
  • Advanced age enhances host susceptibility to secondary pneumococcal pneumonia and is associated with worsened disease outcomes. (lu.se)
  • Pneumonia occurs if the organisms are inhaled into the lungs and not cleared (again, viral infection, or smoking-induced ciliary paralysis might be contributing factors). (wikipedia.org)
  • Pneumonia (lung infection) - Pneumonia causes the lungs to fill with fluid. (hnhu.org)
  • Nasopharyngeal colonization occurs in biofilms and precedes infection. (lu.se)
  • Nicotine-containing E-cigarette vapour increased mouse nasal PAFR expression, and nasopharyngeal pneumococcal colonisation. (ersjournals.com)