• conjugate vaccine
  • In subjects 11 to 18 years of age, lower levels for antibodies to pertactin were observed when BOOSTRIX was administered concomitantly with meningococcal conjugate vaccine (serogroups A, C, Y, and W-135) as compared with BOOSTRIX administered first. (nih.gov)
  • All Hib vaccines that are currently used are conjugate vaccine. (wikipedia.org)
  • Prior to introduction of the conjugate vaccine, Hib was a leading cause of childhood meningitis, pneumonia, and epiglottitis in the United States, causing an estimated 20,000 cases a year in the early 1980s, mostly in children under 5 years old. (wikipedia.org)
  • Since optimal contact between B cells and T cells is required (via MHC II) to maximize antibody production, it is reasoned that the conjugate vaccine allows B cells to properly recruit T cells, this is in contrast to the polysaccharide form in which it is speculated that B cells do not interact optimally with T cells leading to the TI interaction. (wikipedia.org)
  • Due to routine use of the Hib conjugate vaccine in the U.S. since 1990, the incidence of invasive Hib disease has decreased to 1.3/100,000 in children. (wikipedia.org)
  • doses
  • A survey conducted by eight different state health departments of 583 physicians indicated approximately one-third had had difficulties in obtaining DTP vaccine, and approximately one-half were following the current recommendations to defer the DTP doses for 18-month-old and 4- to 6-year-old children. (cdc.gov)
  • Practitioners should not administer partial doses of DTP vaccine in an effort to make the vaccine go further, since the degree of protection afforded by such partial doses is not certain. (cdc.gov)
  • It is important for practitioners to establish recall systems to ensure that children whose doses are deferred are recalled for the DTP vaccine they need once supplies become available. (cdc.gov)
  • Adjusted analysis of the antibody responses indicated that after three doses mean titers among preterm infants to each vaccine component were comparable to those of full term infants. (biomedsearch.com)
  • Tetanus toxoid should be given to infants from 6 to 8 weeks old, in three doses with 4 to 8 week intervals. (wikipedia.org)
  • Oral polio vaccines cause about three cases of vaccine-associated paralytic poliomyelitis per million doses given. (wikipedia.org)
  • In 2001 it produced ca. 110 million doses of vaccines and 300 thousand vials of hyperimmune sera. (wikipedia.org)
  • infections
  • The live attenuated BCG vaccine developed against tuberculosis has been shown to have strong beneficial effects on the ability to combat non-tuberculosis infections. (wikipedia.org)
  • However, Hib remains a major cause of lower respiratory tract infections in infants and children in developing countries where the vaccine is not widely used. (wikipedia.org)
  • Unencapsulated H. influenzae strains are unaffected by the Hib vaccine and cause ear infections (otitis media), eye infections (conjunctivitis), and sinusitis in children, and are associated with pneumonia. (wikipedia.org)
  • The World Health Organization (WHO) reports that licensed vaccines are currently available for twenty-five different preventable infections. (wikipedia.org)
  • injection
  • The adsorbed diphtheria, tetanus and acellular pertussis components are combined with aluminum phosphate (as adjuvant), 2-phenoxyethanol (not as a preservative) and water for injection. (rxlist.com)
  • The most common reactions are mild fever, loss of appetite, transient redness, swelling, or pain at the site of injection, occurring in 5-30% of vaccine recipients. (wikipedia.org)
  • Between 10 and 50% of people given the whole-cell vaccines develop redness at the injection site or fever. (wikipedia.org)
  • The pertussis component of the original DPT vaccine accounted for most of the minor local and systemic side effects in many vaccinated infants (such as mild fever or soreness at the injection site). (wikipedia.org)
  • Between 10 and 50% of people given the whole-cell vaccines develop redness, swelling, soreness or tenderness at the injection site and/or fever, less than 1% experience febrile seizures or long periods of crying, and less than 1 out of every 1,000 to 2,000 people vaccinated have a hypotonic-hyporesponsive episode. (wikipedia.org)
  • pathogen
  • Vaccines can be prophylactic (example: to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic (e.g., vaccines against cancer are being investigated). (wikipedia.org)
  • childhood
  • In the early 1980s, the organization joined with the American Academy of Pediatrics to draft the original legislation for the National Childhood Vaccine Injury Act of 1986, which created a federal vaccine injury compensation program, mandated that doctors give parents vaccine benefit and risk information, and required the recording and reporting of vaccine injuries and deaths (see Vaccine Adverse Event Reporting System). (wikipedia.org)
  • In the latter 20th century, vaccinations helped to reduce the incidence of childhood pertussis in the United States. (wikipedia.org)
  • BOOSTRIX
  • Syncope (fainting) can occur in association with administration of injectable vaccines, including BOOSTRIX. (nih.gov)
  • In subjects 19 to 64 years of age, lower levels for antibodies to FHA and pertactin were observed when BOOSTRIX was administered concomitantly with an inactivated influenza vaccine as compared with BOOSTRIX alone. (nih.gov)
  • Do not mix BOOSTRIX with any other vaccine in the same syringe or vial. (nih.gov)
  • Humans
  • In June 2011, the third phase test of dengue vaccine involving 800 humans with ages of 2 and 14 years old have been held in 5 community health centre around Jakarta and will be conducted also in Bandung, West Java and Denpasar, Bali with 800 and 400 participants, respectively. (wikipedia.org)
  • The first test was performed on a limited number of soldiers and the second phase was conducted on a small number of children and if within the next 5 years the vaccine is found to be safe for humans, government will apply the dengue vaccine to public. (wikipedia.org)
  • previous vaccine
  • If you have had a brain problem like coma, lowered level of awareness, or seizures from an unknown cause within 7 days of a previous vaccine that has pertussis. (drugs.com)
  • Your child should not receive this vaccine if he or she has a neurologic disorder or disease affecting the brain (or if this was a reaction to a previous vaccine). (cigna.com)
  • antibodies
  • some individuals are "non-responders" to certain vaccines, meaning that they do not generate antibodies even after being vaccinated correctly. (wikipedia.org)
  • routine
  • Diphtheria-tetanus vaccine should not be substituted in the routine DTP vaccine schedule for 18-month-old and 4- to 6-year-old children. (cdc.gov)
  • The occurrence of tetanus in the United States has decreased markedly because of the routine use of tetanus toxoid. (cdc.gov)
  • citation needed] After routine use of the vaccine in the United States from 1980 to 1990, the rate of invasive Hib disease decreased from 40-100 per 100,000 children down to fewer than 1 per 100,000. (wikipedia.org)
  • The World Health Organization and Center for Disease Control and Prevention recommend all children be vaccinated for pertussis and that it be included in routine vaccinations. (wikipedia.org)
  • outbreaks
  • citation needed] however, both suggest that shorter intervals may be appropriate in some circumstances, such as for protection in pertussis outbreaks. (wikipedia.org)