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  • vivo
  • Clark C, Werring D, Miller D (2000) Diffusion imaging of the spinal cord in vivo: estimation of the principal diffusion and application to multiple sclerosis. (springer.com)
  • Improved non-invasive magnetic resonance (MR) characterisation of in vivo models of focal ischaemic insults such as transient ischaemic attack (TIA) and perinatal arterial ischaemic stroke (AIS) may assist diagnosis, outcome prediction and treatment design. (springer.com)
  • fMRS is based on the same principles as in vivo magnetic resonance spectroscopy (MRS). However, while conventional MRS records a single spectrum of metabolites from a region of interest, a key interest of fMRS is to detect multiple spectra and study metabolite concentration dynamics during brain function. (wikipedia.org)
  • perfusion
  • In 1990, the MGH-NMR Center received the first clinical echo planar imaging (EPI) MRI instrument, capable of forming MRI images in 25 ms. The EPI method proved extremely powerful in the study of both perfusion and diffusion by allowing Kwong, and others, to evaluate dynamic changes in signal, such as the flow of blood labeled with injected magnetic contrast agents through the organ systems. (wikipedia.org)
  • tissue
  • In spite of a chronically reduced ADC, typically associated with ischaemia-induced energy failure, a 31 P MRS-detectable reduction in the phosphocreatine (PCr) to gamma adenosine triphosphate (γATP) ratio was not observed at any time point in either age group, suggesting dissociation of tissue water diffusion and metabolic changes within the ET-1-induced lesion. (springer.com)
  • van der Graaf M, Schipper RG, Oosterhof GO, Schalken JA, Verhofstad AA, Heerschap A. Proton MR spectroscopy of prostatic tissue focused on the detection of spermine, a possible biomarker of malignant behavior in prostate cancer. (springer.com)
  • Gradient
  • An NMR spectrometer typically consists of a spinning sample-holder inside a very strong magnet, a radio-frequency emitter and a receiver with a probe (an antenna assembly) that goes inside the magnet to surround the sample, optionally gradient coils for diffusion measurements and electronics to control the system. (wikipedia.org)
  • investigate
  • Most frequently, NMR spectroscopy is used by chemists and biochemists to investigate the properties of organic molecules, although it is applicable to any kind of sample that contains nuclei possessing spin. (wikipedia.org)
  • atoms
  • This type of spectroscopy determines the physical and chemical properties of atoms or the molecules in which they are contained. (wikipedia.org)
  • The presence or absence of imino proton resonances, or of coupling between 15N atoms across a hydrogen bond, indicates the presence or absence of basepairing. (wikipedia.org)
  • Mechanisms
  • Oh J, Henry RG, Genain C, Nelson SJ, Pelletier D (2004) Mechanisms of normal appearing injury related to pericallosal T1 lesions in multiple sclerosis using directional diffusion tensor and H-1 MRS imaging. (springer.com)
  • findings
  • MR spectroscopy using 2D-CSI (a multi voxel technique) of the corpus callosum, basal ganglia, lobar white matter and brainstem may reveal areas of injury and quantification of the metabolites from these areas may be used to correlate with imaging findings and clinical evaluation. (clinicaltrials.gov)
  • chemical
  • After chemical shift imaging (point-resolved spectroscopy, repetition time/echo time 1,500 ms/135 ms) of a supraventricular volume of interest of 8×8×2 cm 3 (64 voxels) MRS peak areas were matched to the results of DTI for the corresponding volume elements. (springer.com)
  • His association with scientific organizations include memberships in Indian Chemical Society, American Physical Society, American Association for the Advancement of Science, Magnetic Resonance Spectroscopy Association of India and the International Diffusion Research Association and the fellowship of Sigma Xi. (wikipedia.org)
  • field
  • Magnetic resonance imaging (MRI) is a diagnostic study that makes pictures of organs of the body using magnetic field and radio frequency pulses that can not be felt. (clinicaltrials.gov)
  • During the scan, the subject lies on a table in a narrow cylinder containing a magnetic field, wearing ear plugs to muffle loud noises that occur with electrical switching of the magnetic fields. (clinicaltrials.gov)
  • To balance the need for temporal resolution and sufficient SNR, fMRS requires a high magnetic field strength (1.5 T and above). (wikipedia.org)
  • Modern NMR spectrometers have a very strong, large and expensive liquid helium-cooled superconducting magnet, because resolution directly depends on magnetic field strength. (wikipedia.org)
  • When placed in a magnetic field, NMR active nuclei (such as 1H or 13C) absorb electromagnetic radiation at a frequency characteristic of the isotope. (wikipedia.org)
  • The resonant frequency, energy of the absorption, and the intensity of the signal are proportional to the strength of the magnetic field. (wikipedia.org)
  • It is common to refer to a 21 T magnet as a 900 MHz magnet, although different nuclei resonate at a different frequency at this field strength in proportion to their nuclear magnetic moments. (wikipedia.org)
  • known
  • It is useful for molecules of up to 100 nucleotides, and as of 2003, nearly half of all known RNA structures had been determined by NMR spectroscopy. (wikipedia.org)
  • Group
  • Multi-voxel spectroscopy provides information about group of voxels and data can be presented in 2D or 3D images, but it requires longer acquisition times and therefore temporal resolution is decreased. (wikipedia.org)
  • The Purcell group at Harvard University and the Bloch group at Stanford University independently developed NMR spectroscopy in the late 1940s and early 1950s. (wikipedia.org)
  • structures
  • The sequential walking methodology is not possible for non-double helical nucleic acid structures, nor for the Z-DNA form, making assignment of resonances more difficult. (wikipedia.org)
  • study
  • 1998) White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy. (springer.com)
  • Consistent with his joint appointment in the Massachusetts Eye and Ear Infirmary, he and his colleagues were able to demonstrate that MRI could be used to study diffusion and flow in the living eye. (wikipedia.org)
  • origin
  • It is a well established notion that animals can detect the Earth's magnetic field, while the biophysical origin of such magnetoreception is still elusive. (searxiv.org)
  • NYC SCA839882012-08-01T00:00:00Furniture download optimal transport theory for a Public SchoolThe Weeks Lerman889202013-01-01T00:00:00Furniture text of Office Furniture for three resonance origin of 12 stories for the Borough of Manhattan Community College. (kar-men.com)
  • allows
  • The formalism allows the calculation of the electric and magnetic fields inside and outside a spherical object and is generally used to calculate either how much light is scattered, the total optical cross section, or where it goes, the form factor. (wikipedia.org)