• DMF differentiation demonstrated a higher OPKA titer at time 1 which suffered thereafter while ATRA or VitD3-differentiated cells steadily increased. (biobender.com)
  • Pearson evaluation between your phenotypic adjustments and OPKA titers shows that CD11c may be a good differentiation marker for HL-60 cells for make use of in pneumococcal OPKA. (biobender.com)
  • In today's study we looked into the relationship between phenotypic and useful changes that take place during differentiation of HL-60 cells with DMF ATRA and VitD3 as time passes. (biobender.com)
  • This data will be useful in optimizing the differentiation process of HL-60 cells for make use of in OPKA to serotype 19F (ATCC) was expanded in Todd-Hewitt broth (Difco Detroit MI USA) with 0.5% yeast extract to the log phase aliquoted in 15% glycerol and frozen at -70℃ for further use. (biobender.com)
  • HL-60 Colec10 cells before and day 1 2 3 4 or 5 5 of differentiation by DMF ATRA or VitD3 were used for OPKA. (biobender.com)
  • We used primary acute myeloid leukemia (AML) samples and human AML cell lines to investigate the regulatory mechanisms of autophagy and its role in AML differentiation. (hindawi.com)
  • Vitamin D3-induced monocytic differentiation resulted in an increased carboxypeptidase M expression in all three cell lines. (uni-regensburg.de)
  • Stem and progenitor cell populations are often heterogeneous, which may reflect stem cell subsets that express subtly different properties, including different propensities for lineage selection upon differentiation, yet remain able to interconvert. (lu.se)
  • A key challenge is to understand how state, but must also afford flexibility in cell-fate choice to permit the different cell-fate options confronting stem and progenitor cell-type diversification and differentiation in response to cells are selected and coordinated such that adoption of a given intrinsic cues or extrinsic signals. (lu.se)
  • Evidence the fate of stem cells has broad ramifications for biomedical suggests that during development or differentiation, cells make science from elucidating the causes of cancer to the use of very precise transitions between apparently stable ``network stem cells in regenerative medicine. (lu.se)
  • Calcitriol elicits anti-tumor effects mainly through the induction of cancer cell apoptosis, cell cycle arrest, differentiation, angiogenesis and the inhibition of cell invasiveness by a number of mechanisms. (jcancer.org)
  • The broad spectrum anti-tumor effects of calcitriol and analogs are mostly based on inhibition of cancer cell proliferation and invasiveness, induction of differentiation and apoptosis, and promotion of angiogenesis. (jcancer.org)
  • Cell culture transfection and differentiation The human promyelocytic leukaemia cell line HL-60 (American Type Culture Collection) was cultured in DMEM 20 (v/v) fetal bovine serum and 10 units/ml penicillin-streptomycin at 37°C under 5% CO2. (conferencedequebec.org)
  • During the differentiation process, the cells were treated with the program chain "pathogene Ai" of the BICOM® optima mobile bioresonance device on three consecutive days in an external mini-incubator at 37 °C for 180 min each. (bioresonance.org)
  • Chemoattractant exposure increases cell volume and potentiates neutrophil migration, but the causal link between these processes is not known. (elifesciences.org)
  • Preventing cell spreading by depolymerizing the actin cytoskeleton with Latrunculin B abrogates this initial volume loss in neutrophil-like differentiated HL-60 (dHL-60) cells ( fig. S1F ). (elifesciences.org)
  • We performed high resolution time-lapse microscopy of mouse and human neutrophils (PMN) and differentiated HL60 neutrophil-like cells (dHL-60) labelled with fluorescent markers of the cytoskeleton and organelles and stimulated with ionomycin, lipopolysaccharides or C. albicans to induce NETosis. (mpg.de)
  • In our study, we have investigated the potential role of OAG in Ca(2)(+) influx-mediated NOX2 activity in neutrophil-like-differentiated HL-60 cells to further characterize second signals involved in the regulation of NOX2. (uni.lu)
  • We now show that HGE bacteria, and the HGE-44 protein, induce IL-8 secretion in a promyelocytic (HL-60) cell line that has been differentiated along the neutrophil lineage with retinoic acid and in neutrophils. (neuroprobe.com)
  • Furthermore, the culture supernatants of the BET-1A cells stimulated with aliquots of bacterial culture containing antimicrobial agents or complement similarly mediated neutrophil migration in vitro. (neuroprobe.com)
  • Through NHE1 inhibition in primary human neutrophils, we show that cell swelling is both necessary and sufficient for rapid migration following chemoattractant stimulation. (elifesciences.org)
  • Neutrophils are a powerful system to study the biophysical demands of cell motility, as they acutely initiate rapid migration following stimulation with chemoattractant. (elifesciences.org)
  • a single cell volume measurement technique, to primary human neutrophils. (elifesciences.org)
  • The cells were differentiated into neutrophils by GGA stimulation like retinoic acid stimulation. (elsevierpure.com)
  • In the case of cells stimulated with 2,3-diGGA, neutrophils were not detected, but the formation of lipid droplets was induced. (elsevierpure.com)
  • 2007 Nucleofected cells were then differentiated to mature neutrophils by suspension in medium containing 1.3% DMSO for 72 hours. (conferencedequebec.org)
  • Neutrophils were identified as Ly6Ghigh cells and by their characteristic high-side-scatter profile. (conferencedequebec.org)
  • Neutrophils are the most common type of granulocyte, a type of white blood cell, found in most mammals. (bioresonance.org)
  • Human promyelocytes (HL-60 cells) were differentiated to functional neutrophils over a period of 5 days by the addition of 1.5 vol% dimethyl sulfoxide to the culture medium. (bioresonance.org)
  • Finally, the basal cell metabolism and the generation of superoxide anion radicals with and without treatment of the functional neutrophils was examined. (bioresonance.org)
  • Treatment with the BICOM® mobile bioresonance device had no significant influence on mitotic activity or cell size of functional neutrophils. (bioresonance.org)
  • were used to establish a 3D organotypic in vitro model containing microtumor spheroids, macrophages, neutrophils, fibroblasts and endothelial cells, allowing for the analysis of tumor-stroma interactions in a controlled and modifiable environment. (ilexlife.com)
  • G-CSF also modulates multiple differentiated functions of human neutrophils, including enhanced oxidative metabolism in response to f- Met-Leu-Phe (f-MLP), increased antibody-dependent cell-mediated cytotoxicity (ADCC), and augmented arachidonic acid release in response to ionophore and chemotactic agents. (ashpublications.org)
  • These effects are all maximal at a concentration of 100 to 500 pmol/L. Using 125I-labeled recombinant human G-CSF, high affinity binding sites were identified on human neutrophils, the myeloid leukemia cell lines KG-1 and HL-60, and the small cell carcinoma cell lines, H128 and H69. (ashpublications.org)
  • The cell line is differentiated using all-trans retinoic acid (ATRA) to generate a cell population that resembles mature granulocytes. (ku.dk)
  • To prove the function of these miRNAs, HL-60, a human acute promyelocytic leukemia cell line, was differentiated by the treatment of alltrans retinoic acid (ATRA). (adacyte.com)
  • Stimulation of ATRA-treated HL-60 by some cytokines altered miRNA expressions. (adacyte.com)
  • ATRA-differentiated HL-60 cells show level of resistance to cytotoxic medicines and loss of life receptor-mediated cell loss of life, and have improved Lyn manifestation which is necessary for their success [64]C[67]. (phytid.org)
  • In addition, carboxypeptidase M expression could be detected in HL-60, U937, and THP-1 myeloid cell lines. (uni-regensburg.de)
  • The cell line HL-60 was established from the peripheral blood of a 35-year-old woman with acute myeloid leukemia (AML FAB M2) in 1976. (laboratorynotes.com)
  • 1979. Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia. (laboratorynotes.com)
  • In this report, we show that biosynthetic (recombinant) human G-CSF enhances colony formation by normal human bone marrow and the human myeloid leukemic cell lines, HL-60 and KG-1, as well as nonhematopoietic small cell lung cancer lines, H128 and H69. (ashpublications.org)
  • 2005 BM-PMN or differentiated HL-60 cells (1×105) had been placed on best wells of the chemotaxis dish with 3-μm skin pores (Receptor Systems Adderbury UK) and permitted to migrate towards recombinant murine MIP-2 (Peprotech) LTB4 and fMLP (Sigma-Aldrich) at concentrations as indicated for thirty minutes (or one hour for HL-60). (conferencedequebec.org)
  • infected cells in a chemotaxis chamber assay, and this movement can be blocked with antibodies to IL-8. (neuroprobe.com)
  • Morphine has been shown to negatively impact macrophage function by impairing the proliferation of macrophage progenitor cells, inhibiting cytokine secretion leading to decreased chemotaxis, hindering the ability of macrophages to directly phagocytize pathogens, and inhibiting nitric oxide production. (uspharmacist.com)
  • For OPKA ONO-4059 granulocytes differentiated from HL-60 have already been utilized as effector cells to reduce your time and effort of isolating refreshing granulocytes from individual peripheral bloodstream (12). (biobender.com)
  • Human granulocyte colony-stimulating factor (G-CSF) is a regulatory glycoprotein that stimulates the production of neutrophilic granulocytes from committed hematopoietic progenitor cells both in vitro and in vivo. (ashpublications.org)
  • Cells extend their membranes during morphogenesis and movement. (elifesciences.org)
  • beta, gamma-imino]triphosphate, p[NH]ppG, and the regulation of binding by the formyl-peptide-receptor agonist, fMet-Leu-Phe, were studied in membranes of differentiated HL-60 cells. (eurekamag.com)
  • CsH inhibited FMLP binding in HL-60 membranes with a Ki (inhibition constant) of 0.10 microM. (rspharmchem.com)
  • CsH inhibited activation by FMLP of high affinity GTPase (the enzymatic activity of alpha-subunits of heterotrimeric regulatory guanine nucleotide-binding proteins) in HL-60 membranes with a Ki of 0.79 microM. (rspharmchem.com)
  • Here we examined the molecular mechanism by which MWCNTs induce M1 polarization using in vitro assays and the murine macrophage cell line, J774A.1. (cdc.gov)
  • Static magnetic fields generated by a 0.5 T MRI unit affects in vitro expression of activation markers and interleukin release in human peripheral blood mononuclear cells (PBMC) [med. (emf-portal.org)
  • Moreover, in vitro differentiated macrophages show the highest specific activity yet described in any tissue. (uni-regensburg.de)
  • Furthermore, the sensitivity towards the yeasts C. albicans and S. cerevisiae is considerably better than obtained in other in vitro cell systems. (ku.dk)
  • were used in the development of a human immunocompetent Organ-on-Chip - a human cell-based in vitro model of the choroid layer of the eye integrating melanocytes and microvascular endothelial cells, covered by a layer of retinal pigmented epithelial cells. (ilexlife.com)
  • G-CSF receptor numbers ranged between 138 and 285 sites per cell with a kd of 77 to 140 pmol/L, consistent with the concentrations of G-CSF that elicit biologic responses in vitro. (ashpublications.org)
  • In this report, we examined the mode of nitrite reductase (PNR) release from a serum-sensitive strain of live P. aeruginosa cells during in vitro treatment with four different antimicrobial agents or human complement. (neuroprobe.com)
  • Moreover, the cell-free media from MWCNT-polarized macrophages induced the migration of neutrophilic cells (differentiated from HL-60). (cdc.gov)
  • When HL-60 was differentiated to neutrophilic cells, the HEstaining shows an increased cytoplasm to nucleus ratio, condensated chromatin, and nuclear segmentation. (adacyte.com)
  • Pulsed electromagnetic fields enhance the induction of cytokines by peripheral blood mononuclear cells challenged with phytohemagglutinin [med. (emf-portal.org)
  • Furthermore, the mixed inhibition of MEK and IKK led to decreased IL-6 mRNA appearance, synergistic lack of cell viability and elevated apoptosis. (phytid.org)
  • These outcomes demonstrate the electricity of 497839-62-0 IC50 MIB/MS as an instrument to recognize dysregulated kinases also to interrogate kinome dynamics as cells react to targeted Rabbit Polyclonal to ACVL1 kinase inhibition. (phytid.org)
  • Sleeping Elegance is far more susceptible to more than expression inhibition than piggyBac and Tol2, the cargo capacity of Sleeping Attractiveness is constrained, and contrary to Tol2 and piggyBac that Inhibitors,Modulators,Libraries are lively in all mamma lian cell kinds tested, Sleeping Elegance display cell form dependent exercise. (p450inhibitors.com)
  • The two monoclonal antibodies MAX.1 and MAX.11 recognize cell surface antigens that are almost undetectable on monocytes but highly expressed on differentiated macrophages. (uni-regensburg.de)
  • Long-term activation of protein kinase c causes chronic Na/H antiporter stimulation in cultured proximal tubule cells. (jci.org)
  • Following this spreading-mediated initial volume loss, the cells swelled significantly, reaching a median volume 15% larger than their resting volumes 20 minutes post-stimulation. (elifesciences.org)
  • On the other hand, when the cells were cultured in the presence of 0.1% FBS instead of 10% FBS, apoptotic cells were induced not only by GGA stimulation but also with 2,3-diGGA. (elsevierpure.com)
  • A mass spectrometry-based approach of IL27 ± calprotectin cell stimulation enlightened a calprotectin modulatory role in the expression of 28 proteins, mostly involved in the mechanism of leukocyte transmigration. (uni.lu)
  • details] [Growth behaviour of human leukemia cells] [med. (emf-portal.org)
  • The aim of this study was to test for the molecular and functional expression of the non-gastric H + /K + ATPase ATP12A/ATP1AL1 in unstimulated and butyrate-stimulated (1 and 10 mM) human myelomonocytic HL-60 cells, to unravel its potential role as putative apoptosis-counteracting ion transporter as well as to test for the effect of the H + /K + ATPase inhibitor SCH28080 in apoptosis. (karger.com)
  • In this paper we describe a new pyrogen assay using the human leukemia cell line HL-60. (ku.dk)
  • Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines. (hsanmartino.it)
  • We studied the effects of CsH in comparison with those of N-t- butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-leucyl-L- phenylalanine (BocPLPLP), a well known formyl peptide receptor antagonist, and of other Cs on activation of N6,2'-O-dibutyryl adenosine 3:5'-monophosphate-differentiated HL-60 cells and human erythroleukemia cells (HEL cells). (rspharmchem.com)
  • Bacterial killing of P. aeruginosa by antimicrobial agents induced PNR release and mediated IL-8 production in human bronchial epithelial (BET-1A) cells. (neuroprobe.com)
  • Accurate and reliable measures of CD4+ T-lymphocytes (CD4+ T-cells) are essential to the assessment of the immune system of human immunodeficiency virus (HIV)-infected persons (1-3). (cdc.gov)
  • While the involvement of actin polymerization in membrane protrusion is well-established, we have a more limited understanding of the role of transmembrane water flow in cell motility. (elifesciences.org)
  • In contrast to the extensive work characterizing the actin regulators that underlie cell motility, we have a relatively poor understanding of the molecular regulators of water influx during cell migration. (elifesciences.org)
  • For F-actin staining 3 BM-PMN cells were fixed for 30 minutes at room temperature in 4% paraformaldehyde (PFA) and permeabilised with 0.5% saponin for 15 minutes prior to Alexa-Fluor-647-phalloidin staining. (conferencedequebec.org)
  • Time-lapse videomicroscopy clearly differentiated these stable microtubule-driven and nocodazole-sensitive extensions from common dynamic actin-driven pseudopodia. (uni.lu)
  • Our data demonstrate that cell swelling complements cytoskeletal inputs for chemoattractant-induced potentiation of migration. (elifesciences.org)
  • This paper will be of interest to cell biologists and biophysicists working on cell migration. (elifesciences.org)
  • Moreover, the expression of EGFP-Syk Y323F interfered with proper cell polarization and it impaired efficient migration of dHL-60 cells. (uni-muenchen.de)
  • de-adhesion of uropods a mechanism that may be conserved in cell migration and invasion. (conferencedequebec.org)
  • As we now have been unable to create proliferating cultures of CTC for inhibitor and biochemical scientific studies, to additional investigate the purpose of the Hedgehog and ErbB pathways in AIPC we have now utilized the androgen independent prostate cancer cell line LNCaP C4 2B. (hdac-inhibitors.com)
  • This is the complete description of the cell line that you selected. (hsanmartino.it)
  • Cell line available for distribution. (hsanmartino.it)
  • After treatment with DMSO the cells differentiate along the granulocytic line (after 4 days in 1,25% DMSO, 72% of the cells become CD11b positive). (hsanmartino.it)
  • Calculation of your drug concentration creating the median impact of 50% development inhibi tion within the LNCaP C4 2B cell line in androgen absolutely free medium was performed through the dose response curves for each drug, and had been similar to these reported within the literature. (hdac-inhibitors.com)
  • Gene expression The affect of DADS therapy on cytokine induced metalloproteinase gene expression was assessed from the SW1353 cell line by TaqMan qRT PCR. (hdac-inhibitors.com)
  • Depending on the cell line, the cells were seeded as follows: 10 4 cells of A375 and SKMEL28, 2x10 4 cells of MNT1 and 1.5x10 4 cells of Me290 and SKMEL23. (ilexlife.com)
  • We explored whether LPL affects (a) lipoprotein transport across bovine aortic endothelial cells or (b) lipoprotein binding to subendothelial cell matrix (retention). (jci.org)
  • The protein-based communication between leukocytes and inflamed endothelial cells leading to diapedesis has been largely investigated and several key players such as IL6, TNFα, or the damage associated molecular pattern molecule (DAMP) calprotectin are now well identified. (uni.lu)
  • Therefore, we examined the inflammatory impact of IL27 on primary endothelial cells and the potentially modulatory effect of calprotectin on both transcriptome and proteome levels. (uni.lu)
  • Effects of short term exposure to 60 Hz electromagnetic fields on interleukin 1 and interleukin 6 production by peritoneal exudate cells [med. (emf-portal.org)
  • The effects depend on frequency, amplitude, and duration of exposure as well as on the characteristics of the targeted cell types. (frontiersin.org)
  • Noteworthy, in recent years the possibility to use EMF exposure to modulate immune cell responses has been proposed and debated ( 6 - 9 ). (frontiersin.org)
  • Exposure to RF-EMF for 60 minutes at 5 cm distance causes a significant reduction in the number of CD4+ T cells, IL-2, IL-10 and IL-17a expressing T cells. (ninamvseeno.org)
  • Chronic lymphoid leukaemia and hairy cell leukaemia due to chronic exposure to benzene: Report of three cases. (cdc.gov)
  • An essential role of syntaxin 3 protein for granule exocytosis and secretion of IL-1α, IL-1β, IL-12b, and CCL4 from differentiated HL-60 cells. (uni.lu)
  • Focal Epithelial Hyperplasia (FEH) or Heck's disease is a rare and benign condition characterized by cell proliferation in the squamous epithelium, which is manifested clinically as verrucous projections. (bvsalud.org)
  • After 30 min incubation at room temperature 40 μL of HL-60 suspension (4×105 per well) and 10 μL of baby rabbit complement (Accurate Chemical Westbury NY USA) were added to the well. (biobender.com)
  • Here, we describe a simple, step-by-step protocol for the swift isolation of mouse DRG, which can be enzymatically dissociated to produce fully differentiated primary neuronal cultures, or processed for downstream analyses, such as immunohistochemistry or RNA profiling. (biomedcentral.com)
  • Required for healthy neuronal functions and normal functions of rapidly growing cells. (medscape.com)
  • In M. Khatami (Ed.), Inflammation, Chronic Diseases and Cancer - Cell and Molecular Biology, Immunology and Clinical Bases (pp. 307-330). (uni.lu)
  • They play an essential part of the innate immune system and as inflammation-mediating cells. (bioresonance.org)
  • They play a two fold role as (i) phagocytes (= scavenger cells) by floating in the circulating blood and forming a cellular defense against invading microbial pathogens as an essential part of the innate immune system [1], and (ii) as inflammation-mediating cells after having entered the inflamed tissue. (bioresonance.org)
  • The cell- ations in these signals (see Table 1 for a glossary of terms). (lu.se)
  • According to the current view, damage-associated molecules released by infected or injured cells, or secreted by innate immune cells generate danger signals activating an immune response. (frontiersin.org)
  • In the present review, we describe and discuss the effects of extremely low frequency (ELF)-EMF and pulsed EMF on cell signals and factors relevant to the activation of danger signals and innate immunity cells. (frontiersin.org)
  • It is well known that the cells of our body emit and receive electromagnetic signals which allow an intra- and intercellular electromagnetic communication [13,14]. (bioresonance.org)
  • To examine the role of protein kinase C as a chronic regulator of proximal tubule Na/H antiporter activity, the effect of phorbol 12-myristate 13-acetate (PMA) on the Na/H antiporter was studied in cultured proximal tubule cells. (jci.org)
  • 13 Morphine has been shown to decrease IL-23 production in murine models, decreasing dendritic cell antimicrobial protein production. (uspharmacist.com)
  • Live cultures imaged by phase contrast microscopy c or fixed neurons imaged by confocal microscopy d can be used to assess various cellular phenotypes including morphology (e.g. cell soma area and axon length), electrophysiology, and protein localisation. (biomedcentral.com)
  • protein patterns of subjects with leish- Cell culture maniasis [17]. (who.int)
  • BACKGROUND: We have recently reported a novel mutation in the beta3 subunit of the platelet fibrinogen receptor (alpha(IIb)beta3D723H) identified in a patient with dominantly inherited macrothrombocytopenia, and we have shown that this mutation promotes a new phenotype in Chinese hamster ovary (CHO) cells, characterized by fibrinogen-dependent, microtubule-driven proplatelet-like cell extensions. (uni.lu)
  • Infected HL-60 cells also demonstrate upregulation of CXCR2, an IL-8 receptor, but not CXCR1. (neuroprobe.com)
  • These results demonstrate that HGE bacteria induce IL-8 production by host cells and, paradoxically, appear to exploit this chemokine to enhance infection. (neuroprobe.com)
  • To varying degrees, these fates also extend to the Such state stability is required in stem and progenitor cells to immediate progeny of stem cells, known as progenitor or support self-renewal and maintenance of the uncommitted transit-amplifying cells. (lu.se)
  • The median age was 29 years (range = 19-60 years). (cdc.gov)
  • Reduced dopamine levels in PC12 cells exposed to low frequency electromagnetic fields [med. (emf-portal.org)
  • Importantly, the growth of LNCaP C4 2B cells is just not impacted by withdrawal of androgens, confirming the androgen independence of these cells and these cells express androgen receptor and PSA. (hdac-inhibitors.com)
  • In addi tion, LNCaP C4 2B cells express a promiscuous kind in the androgen receptor, possessing the most AR frequent sub stitution, which can be repeatedly observed in prostate cancer selleck chemical tissue specimens of individuals with AIPC. (hdac-inhibitors.com)
  • We have recently reported that nitrite reductase, a bifunctional enzyme located in the periplasmic space of Pseudomonas aeruginosa , could induce interleukin-8 (IL-8) generation in a variety of respiratory cells, including bronchial epithelial cells (K. Oishi et al. (neuroprobe.com)
  • Differentiated HL-60 can be an effector cell trusted for the opsonophagocytic-killing assay (OPKA) to measure efficacy of pneumococcal vaccines. (biobender.com)
  • In a luminol enhanced chemilumimetric assay the responsiveness of differentiated HL-60 cells is tested towards Salmonella typhimurium, Bacillus subtilis, Saccharomyces cerevisiae, Candida albicans, lipopolysaccharide (LPS) and lipoteichoic acid (LTA). (ku.dk)
  • Overall these results indicate that the HL-60 cell assay possibly could be evolved to a supplementary assay for the known pyrogenic detection assays. (ku.dk)
  • The transfected cells had been subjected to a chromosomal transposition assay to deter mine their transposition action. (p450inhibitors.com)
  • MWCNTs, but not CB, induced the expression of CD68, a M1 cell surface marker, and the expression and activity of inducible nitric oxide synthase, a M1 intracellular marker, indicating M1 polarization. (cdc.gov)
  • Opioids have considerable effects on cellular function across many immune cell lineages, affecting both the innate and adaptive immune systems. (uspharmacist.com)
  • 11,12 Dendritic cells are essential to the innate immune system through their presentation of foreign antigens to T-cells. (uspharmacist.com)
  • For example, hyper-activation of Lyn or Hck continues to be connected with imatinib level 497839-62-0 IC50 of resistance in CML individuals and cell tradition versions [21]C[24], albeit the systems where these kinases donate to imatinib level of resistance isn't well understood. (phytid.org)
  • We have demonstrated that piggyBac and Tol2 show substantial transposition activity in quite a few cell lines. (p450inhibitors.com)
  • The nature of the stem cell substates and their relationship to commitment to differ- entiate and lineage selection can be elucidated in terms of a landscape picture in which stable states can be defined mathematically as attractors. (lu.se)
  • In terminally differentiated cell fate is coupled to appropriate regulation of the alternative cells, transcriptional networks must be stable and irreversible, pathways. (lu.se)
  • My lab studies the mechanism and regulation of immune checkpoints, using a combination of biophysical, cell biological and immunological approaches. (mpg.de)
  • Following chemoattractant-uncaging, the cells spread and transformed into a motile, amoeboid state with high persistence ( Fig. 1C ). (elifesciences.org)
  • Similarly, GATA-1 has been shown to induce lineage switching expression values even if, for simplicity, we assume only ``on'' of committed cells in hematopoiesis, first in cell lines (Kulessa and ``off'' states for each gene. (lu.se)
  • SPECIES) you will go to the corresponding index (e.g., index of species), while by clicking on a specific term (e.g., retinoblastoma) you will go to the list of corresponding cell lines (e.g., retionoblastoma cell lines). (hsanmartino.it)
  • See homonymous cell lines in other collections and catalogues. (hsanmartino.it)
  • Hall marks on the majority of prostate cancers in vivo and traits not shared with other established pros tate cancer cell lines which include PC3 and DU145. (hdac-inhibitors.com)
  • CloneSeq - Single-cell clonal 3D culture and analysis protocol. (ilexlife.com)
  • These pieces of evidence confirmed that PNR released in the aliquots of bacterial culture was responsible for IL-8 production in the BET-1A cells. (neuroprobe.com)
  • Are some particles more likely than others to infect a cell, become neutralized, or activate an immune response? (mpg.de)
  • By discussing the EMF modulating effects on cell functions, we envisage the use of EMF as a therapeutic agent to regulate immune responses associated with wound healing. (frontiersin.org)
  • The immune system is constituted by a very complex network of cells, tissues, and organs that through soluble factors and direct cell-to-cell contacts interact among themselves and with cells belonging to other (organ) systems. (frontiersin.org)
  • Perturbing agents, such as toxic compounds ( 1 ), ionizing radiation ( 2 ), and some pathogens ( 3 ) can compromise the integrity of the immune system as they damage immune cells and/or irreversibly alter some immune functions. (frontiersin.org)
  • 2 Previous studies have evaluated the opioid receptors on a wide array of immune cells. (uspharmacist.com)
  • 2008). Historically, this concept is highlighted by the experi- factors are key intrinsic regulators of these fate decisions and mental phenomenon of lineage reprogramming, for example, that fate choice involves modulating networks of transcription by the conversion of fibroblasts to muscles cells following trans- factors. (lu.se)
  • The Journal of Cell Biology. (wikipedia.org)
  • Understanding cell-fate decisions in stem cell populations is a major goal of modern biology. (lu.se)
  • In reality, gene somatic cells to a pluripotent cell state by a handful of transcrip- expression is graded, making the potential gene expression tion factors (Takahashi and Yamanaka, 2006). (lu.se)
  • These cells were initially isolated and characterised following growth in castrated athymic mice of androgen http://www.selleckchem.com/products/arq-197.html dependent LNCaP prostate cancer cells from your web site of bony metastasis. (hdac-inhibitors.com)
  • The measurement of CD4+ T-cell levels has been used to establish decision points for initiating Pneumocystis carinii pneumonia prophylaxis (12) and antiviral therapy (13) and to monitor the efficacy of treatment (14-16). (cdc.gov)
  • Experimental and observational studies also suggest that men who keep cell phones in their trouser pockets have significantly lower sperm counts and significantly impaired sperm motility and morphology, including mitochondrial DNA damage. (ninamvseeno.org)