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UrgencyBladderIdiopathic detrusor overactivityLeakageOveractivityUrodynamicContractionsNocturiaAnti-incontinenceEtiologyUrethralStressNeurologicMicturitionMorbidityCommonlyDiagnosisNocturnalUrinationAbnormalCognitiveIntermittentUrine lossPatientsFunctionalWeaknessStimulationEvaluationWomenDurationUnpredictableTreatmentSeverityLossOrgasmLowerStudyPressureCombinationExperiencePainImprovement
Urgency4
  • As a result of dependence upon higher brain centers, certain lesions or diseases of the brain (eg, stroke, cancer, dementia) can result in a loss of voluntary control of the normal micturition reflex as well as symptoms such as urinary urgency. (medscape.com)
  • The etiology of the urinary urgency that causes urge incontinence has not yet been fully elucidated, although some peripheral nerves, as well as the central nervous system, may be involved in muscle hypersensitivity and the reduced effectiveness of smooth muscle relaxation ( 3 ). (spandidos-publications.com)
  • The typical clinical presentation includes urgency and/or urge incontinence, frequency and nocturia, with urgency being the commonest symptom. (sgh.com.sg)
  • Urgency incontinence , also known as overactive bladder, is involuntary urination or a very strong desire or urgency to urinate. (healthybladderclub.com)
Bladder24
  • The normal function of the urinary bladder is to store and expel urine in a coordinated, controlled fashion. (medscape.com)
  • [ 1 ] Neurogenic bladder is a term applied to urinary bladder malfunction due to neurologic dysfunction emanating from internal or external trauma, disease, or injury. (medscape.com)
  • Symptoms of neurogenic bladder range from detrusor underactivity to overactivity, depending on the site of neurologic insult. (medscape.com)
  • The urinary sphincter also may be affected, resulting in sphincter underactivity or overactivity and loss of sphincter coordination with bladder function. (medscape.com)
  • The pons is responsible for coordinating the activities of the urinary sphincters and the bladder. (medscape.com)
  • When the bladder becomes full, the stretch receptors of the detrusor muscle send a signal to the pons, which in turn notifies the brain. (medscape.com)
  • The results from the selected RCTs failed to demonstrate any statistically significant improvements in urinary incontinence, although acupuncture or acupressure did exhibit favorable effects on overactive bladder symptoms and quality of life, in comparison with other conventional therapies. (spandidos-publications.com)
  • Stress incontinence occurs when the bladder pressure exceeds urethral resistance as a result of an increased abdominal pressure, for example due to sneezing or coughing ( 2 ). (spandidos-publications.com)
  • Acupuncture was initially described as a successful treatment for certain overactive bladder symptoms in the 1980s ( 4 , 5 ), and, since then, a number of clinical trials on incontinence have been carried out ( 6 - 8 ). (spandidos-publications.com)
  • Therefore, the coordination of the autonomic and somatic nerves to the bladder and urethra is important not only in micturition, but also in incontinence. (spandidos-publications.com)
  • Urinary incontinence is loss of bladder Bladder A musculomembranous sac along the urinary tract. (lecturio.com)
  • Damage due to surgery or trauma near/on the bladder Bladder A musculomembranous sac along the urinary tract. (lecturio.com)
  • The overactive bladder is defined as a bladder storage / filling disorder, where involuntary bladder contractions occur, causing patient's symptoms. (sgh.com.sg)
  • In general, drugs improve detrusor instability by inhibiting the contractile activity of the bladder. (sgh.com.sg)
  • Medications that relax the bladder can be helpful for relieving symptoms of overactive bladder and reducing episodes of urge incontinence. (healthybladderclub.com)
  • In a normal bladder capacity of 400 to 500 mL, a rise in detrusor pressure of 15 cm H 2 O or less is considered to be normal.Decreased bladder compliance is diagnosed when pressure rise at normal capacity exceeds 15 cm H 2 O . Detrusor instability is a urodynamic diagnosis. (healthybladderclub.com)
  • Some common complications resulting from overactive bladder may include: Disruptive quality of life Diminished sexual activity Reduced social interaction Depression Dehydration Fatigue Lower productivity Urinary tract infections Skin irritation and infections Bladder stones Falls and fractures in elderly. (healthybladderclub.com)
  • An overactive bladder is when there is a sudden urge to urinate that may be difficult to control and can happen even though the bladder is not full. (healthybladderclub.com)
  • Stress incontinence is a weakness of the bladder or sphincter muscles. (healthybladderclub.com)
  • Overflow incontinence , also known as after-dribble, is a consequence of not emptying the bladder properly. (healthybladderclub.com)
  • Summary Objective:, The primary goal of overactive bladder (OAB) treatment is to reduce symptoms and improve health-related quality of life (HRQoL). (academicconcepts.net)
  • Three patient-reported outcome (PRO) measures assessed symptom improvement and treatment satisfaction: the Patient Perception of Bladder Condition (PPBC) scale, a Visual Analogue Scale (VAS), the Overactive Bladder Questionnaire (OAB-q). (academicconcepts.net)
  • This study identified and compared clinical guidelines on three urological conditions (interstitial cystitis/bladder pain syndrome (IC/BPS), overactive bladder, and stress urinary incontinence) affecting adult women. (bvsalud.org)
  • Neurogenic bladder can cause overflow incontinence. (benwhite.com)
Idiopathic detrusor overactivity2
  • In 90% of women with OAB, no recognizable cause can be found - Idiopathic detrusor overactivity. (sgh.com.sg)
  • Objective, To evaluate the long-term clinical outcome in women with idiopathic detrusor overactivity (IDO) and to identify significant prognostic factors. (academicconcepts.net)
Leakage4
  • Stress incontinence is defined as an involuntary leakage when the abdominal pressure increases, whereas urge incontinence occurs as a result of uncontrolled abnormal detrusor contractions that exceed the urethral pressure ( 2 ). (spandidos-publications.com)
  • Urinary incontinence (UI) is the involuntary leakage of urine. (lecturio.com)
  • 62.5% reported urinary leakage for 5-9 years. (bvsalud.org)
  • There were several allusions to physical and psychological damages caused by urinary incontinence: 33.5% to psychosocial interactions, 23.3% to sex life, 41.9% reported depression and social isolation, 27.9% sleep disorders and 76.7% embarrassment due to urine leakage. (bvsalud.org)
Overactivity1
  • but in the presence of neurological diseases, it is known as neurogenic detrusor overactivity. (sgh.com.sg)
Urodynamic2
  • Urodynamic study revealing detrusor instability in a 75-year-old man with urge incontinence. (medscape.com)
  • Urge incontinence at presentation was associated with treatment failure (P= 0.001) as was nocturia (P= 0.04), but urodynamic variables were not associated with outcome. (academicconcepts.net)
Contractions1
  • Note the presence of multiple uninhibited detrusor contractions (phasic contractions) that is generating 40- to 75-cm H2O pressure during the filling cystometrogram (CMG). (medscape.com)
Nocturia1
Anti-incontinence1
  • Abstract Objective To critically evaluate sling outcomes and revisit the realistic goals of anti-incontinence surgery. (academicconcepts.net)
Etiology1
Urethral4
  • The PMC coordinates the urethral sphincter relaxation and detrusor contraction to facilitate urination. (medscape.com)
  • This voiding reflex causes the urethral sphincters to open while facilitating the detrusor to contract and expel the urine. (medscape.com)
  • Results from a recent pilot study by Kuismanen et al suggested that urethral injection of a combination of patient-derived adipose stem cells (ASCs) and collagen can improve the symptoms of stress urinary incontinence in women, possibly providing a nonsurgical alternative to sling procedures for this condition. (medscape.com)
  • It stimulates the pelvic floor and urethral muscles, and inhibits detrusor muscle contractility. (sgh.com.sg)
Stress4
  • All five women in the study, each of whom received ASCs and collagen for stress urinary incontinence, demonstrated subjective improvement. (medscape.com)
  • EMG is usually not performed in cases of stress urinary incontinence or cases in which a central nervous system (CNS) lesion is producing the incontinence. (medscape.com)
  • Stress and urge incontinence are the two most common types of urinary incontinence, and mixed incontinence, which is a combination of the two, is also prevalent. (spandidos-publications.com)
  • This is opposed to stress incontinence, the other most common type, which is worsened by abdominal pressure/coughing/laughing/etc and can be caused by pelvic floor prolapse secondary to multiple childbirths etc. (benwhite.com)
Neurologic2
  • F - TTP always seems like too many disparate symptoms but just remember the pentad: thrombocytopenia, microangiopathic hemolytic anemia, neurologic symptoms, renal failure, and fever. (benwhite.com)
  • 12250 ='Vertigo - dizziness' 12300 ='Weakness (neurologic)' 12350 ='Disorders of speech, speech disturbance' 12351 ='Stuttering, stammering' 12352 ='Slurring' 12400 ='Other symptoms referable to the nervo. (cdc.gov)
Micturition1
  • It causes a 20% or more reduction of frequency of micturition and a 45% reduction in incontinence episodes. (sgh.com.sg)
Morbidity1
Commonly1
  • A - This patient has urge incontinence, which is commonly caused by detrusor instability (and can be treated with anticholinergics like oxybutynin). (benwhite.com)
Diagnosis1
  • Once urinary tract infection has been excluded, it is possible to establish a working diagnosis based on the patient's description of symptoms. (sgh.com.sg)
Nocturnal5
  • Nocturnal (nighttime) incontinence (that is, enuresis) is usually not diagnosed until age 7. (msdmanuals.com)
  • Both nocturnal and diurnal incontinence are symptoms-not diagnoses-and necessitate consideration of an underlying cause. (msdmanuals.com)
  • About 0.5% of adults continue to have nocturnal wetting episodes. (msdmanuals.com)
  • The less common is the symptom of bed wetting (nocturnal enuresis). (sgh.com.sg)
  • It is helpful in patients with troublesome nocturnal urinary symptoms. (sgh.com.sg)
Urination1
Abnormal1
  • 11651 ='Nailbiting' 11652 ='Thumbsucking' 12000 ='Abnormal involuntary movements' 12050 ='Convulsions' 12070 ='Symptoms of head, NEC' 12100 ='Headache, pain in head' 12150 ='Memory, disturbances of' 12200 ='Disturbances of sensation' 12201 ='Loss of feeling (anesthesia)' 12202 ='Increased sensation (hyperesthesia)' 12203 ='Abnormal sensation (paresthesia)' 12204 ='Other disturbances of sense, includin. (cdc.gov)
Cognitive1
  • Idiopathic normal pressure hydrocephalus (INPH) is a syndrome of ventriculomegaly, gait impairment, cognitive decline and incontinence that occurs in an elderly population prone to many types of comorbidities. (biomedcentral.com)
Intermittent1
Urine loss1
Patients3
  • Patients with urinary incontinence should undergo a basic evaluation that includes a history, physical examination, and urinalysis. (medscape.com)
  • Urge incontinence was reported by 24.4% to 33.3% of patients. (academicconcepts.net)
  • Methods:, VESIcare Open-Label Trial was a 12-week, open-label, flexible-dosing study in patients with OAB symptoms for , 3 months. (academicconcepts.net)
Functional1
  • Functional incontinence happens when you know you need to urinate, but due to mental or physical reasons, such as dementia or impaired mobility, cannot make it to the bathroom in time. (healthybladderclub.com)
Weakness1
  • VALUE RFVF 10050 ='Chills' 10100 ='Fever' 10120 ='Other symptoms of body temperature' 10121 ='Feeling cold' 10122 ='Feeling hot' 10123 ='Feeling hot and cold' 10150 ='Tiredness, exhaustion' 10200 ='General weakness' 10250 ='General ill feeling' 10300 ='Fainting (syncope)' 10350 ='Symptoms of fluid abnormalities' 10351 ='Edema' 10352 ='Excessive sweating, perspiration' 10353 ='Excessive thirst' 10400 ='Weight gain' 10450 ='Weight loss' 10451 ='Recent weight loss' 10452 ='Underweight' 10460 ='Symptoms of face, not elsewhere class. (cdc.gov)
Stimulation2
  • The detrusor muscle is relaxed by sympathetic stimulation that originates from the lumbar spinal cord T11-L2 region, and contracted by parasympathetic stimulation from the sacral spinal cord S2-4 region. (spandidos-publications.com)
  • Many animal studies involving electrical stimulation of nerves of the lower urinary tract use stimulation amplitudes that exceed those used clinically (â ¼1Tm). (bvsalud.org)
Evaluation1
  • An initial evaluation should include an assessment of the patient's symptoms, detailed physical examination and urinalysis. (sgh.com.sg)
Women7
Duration1
  • Median follow up was 8 years (6,9), and the duration of symptoms was 13 years (9,18). (academicconcepts.net)
Unpredictable2
  • You could be sitting, walking, eating, or doing absolutely nothing when that sudden urge strikes an unpredictable problem that can lead to a fair bit of anxiety and nervousness in your daily life. (healthybladderclub.com)
  • Individual response is unpredictable, although the presence of urge incontinence is associated with a significantly worse prognosis. (academicconcepts.net)
Treatment3
Severity2
  • Frequency Volume Chart - A chart of the timing and volume of output to indicate the severity of the problem. (sgh.com.sg)
  • Disease symptoms fluctuated in severity and QoL were worse in nonresponders to therapy (P (academicconcepts.net)
Loss2
Orgasm1
  • 11602 ='Homosexuality, concerns with' 11603 ='Impotence' 11604 ='Premature ejaculation' 11605 ='Masturbation excessive, concerns about' 11606 ='Orgasm, problem with' 11650 ='Oth symptoms/problems relat to psycho. (cdc.gov)
Lower1
  • The standardization of terminology of lower urinary tract function in children and adolescents: Updated report from the standardization committee of the International Children's Continence Society. (msdmanuals.com)
Study1
Pressure1
  • 10500 ='Chest pain and related symptoms' 10501 ='Chest pain' 10502 ='Chest discomfort, pressure, tightness' 10503 ='Burning sensation in the chest' 10550 ='Pain, specified site not referable to. (cdc.gov)
Combination1
  • Any one or a combination of these symptoms can occur. (sgh.com.sg)
Experience1
  • Emotions, experienced in higher brain centers, may exert downstream effects on the PMC, which is why some people can experience incontinence with excitment or fear. (medscape.com)
Pain1
  • 10551 ='Rib pain' 10552 ='Side pain, flank pain' 10553 ='Groin pain' 10554 ='Facial pain' 10600 ='Pain and related symptoms, generalize. (cdc.gov)
Improvement1
  • Main outcome measure, Subjective assessment of overall improvement on a 4-point scale followed by scoring of short forms of the urogenital distress inventory and incontinence impact questionnaire. (academicconcepts.net)