• Repeated use of cocaine can also lead to cocaine use disorder, also called addiction. (medlineplus.gov)
  • A separate category was included for hard-drug users not known to use crack cocaine to have a group with comparable levels of social deprivation, addiction related problems, and difficulty in accessing health services. (cdc.gov)
  • A growing number of children and young adults are seeking help for cocaine addiction, a report by a leading drugs charity has claimed. (bbc.co.uk)
  • Though a dampened response to drug images might appear helpful in those struggling with addiction, the impaired response to other emotional stimuli among recent cocaine users could indicate a general difficulty in sustaining motivated attention," said Rita Goldstein, director of Brookhaven's Neuropsychoimaging Group. (sciencedaily.com)
  • Sleep deprivation may pave the way to cocaine addiction. (sciencedaily.com)
  • But it's unclear how sleep deprivation contributes to cocaine addiction. (sciencedaily.com)
  • The newest treatment for cocaine addiction may come from a drug that's already being used to battle high blood pressure and is showing some experimental benefits in treating post-traumatic stress disorder (PTSD) as well. (time.com)
  • What this means for humans being treated for cocaine addiction is that while a history of abusing the drug might forever remain fresh in memory, the pleasant associations - the thrill of the score, the anticipation of the high, the first rush of the drug - would be dulled. (time.com)
  • Unlike opioid addiction or alcoholism, both of which can be at least partly battled with medications, cocaine addiction still must be treated entirely with non-pharmacological weapons. (time.com)
  • The second part discusses the social aspects of the addiction to cocaine. (bvsalud.org)
  • TSA screeners say they found about 3 pounds of cocaine hidden in raw meat in a passenger's luggage at Mineta San Jose International Airport. (cnn.com)
  • A 24-year-old man was arrested at Mineta San Jose International Airport in California after airport security officials discovered about 3 pounds of cocaine smuggled inside raw meat in his checked luggage, according to the Transportation Security Administration. (cnn.com)
  • NOGALES, Ariz. - Federal authorities say a Mexican man tried to smuggle more than 7 pounds of cocaine into Arizona by hiding it in his wheelchair's seat cushion. (foxnews.com)
  • As seen in the above evidence photo, agents subsequently discovered about five pounds of cocaine duct taped to Gomez's legs. (thesmokinggun.com)
  • According to the 2019 National Survey on Drug Use and Health, among adolescents aged 12 to 17 years, the percentage who were past year cocaine users decreased from 2.1% (508,000 adolescents) in 2002 to 0.4% (97,000 adolescents) in 2019. (medscape.com)
  • Among the same age group, the percentage with a past year cocaine use disorder declined from 0.4% (105,000 adolescents) in 2002 to less than 0.1% (5,000 adolescents) in 2019. (medscape.com)
  • Globally, in 2019, cocaine was used by an estimated 20 million people (0.4% of adults aged 15 to 64 years). (wikipedia.org)
  • 15, 2019 Scientists have revealed neuronal mechanisms underlying the formation and retrieval of cocaine use-associated memories. (sciencedaily.com)
  • Jan. 16, 2019 A study finds a surprising response to cocaine in a novel strain of mutant mice -- they failed to show hyperactivity seen in normal mice when given cocaine and didn't run around. (sciencedaily.com)
  • The United Kingdom had the highest prevalence of cocaine use among adults in Europe in 2019 at almost three percent of adults using during the year. (statista.com)
  • Trends in the prevalence of marijuana, cocaine , and other illegal drug use national YRBS: 1991-2019. (msdmanuals.com)
  • [ 4 ] However, accidental ingestion of cocaine, passive inhalation of crack cocaine smoke, and transmission through breast milk have been reported as means of cocaine exposure in infants. (medscape.com)
  • Several pulmonary complications are associated with the inhalation of crack cocaine (e.g., intensive cough, hemoptysis, shortness of breath, chest pain, acute bilateral pulmonary infiltrates, thermal airway injury, pneumothorax and noncardiogenic pulmonary edema, production of carbonaceous sputum, and exacerbation of asthma) ( 9 ). (cdc.gov)
  • We used univariate analyses to compare the characteristics of crack cocaine users, other hard-drug users (predominantly heroin users but excluding those who used only alcohol and marijuana), and those not known to use drugs. (cdc.gov)
  • Of course, the joke is funnier if you know its true punch line: Two decades later, my father really did become a drug addict, hooked on nothing so mild as marijuana, but on cocaine. (nymag.com)
  • I've had a mild interest in cocaine ever since my interest in drugs spawned (about the time I began to use marijuana), but I had never seen it or been offered it. (erowid.org)
  • T he usual assumption is that sales of cocaine, marijuana, and heroinwould be carefully regulated if made legal. (prospect.org)
  • I've had people tell me that it's much easier for them to go and get a gram of cocaine now than it is to get a gram of marijuana,' said Const. (cbc.ca)
  • Some countries, such as the Netherlands, make the distinction between soft and hard drugs (e.g. alcohol and marijuana vs cocaine). (bvsalud.org)
  • The drug use section (variable name prefix DUQ) includes questions on lifetime and current use of marijuana, cocaine and the intravenous use of illicit drugs. (cdc.gov)
  • Lason W. Neurochemical and pharmacological aspects of cocaine-induced seizures. (medscape.com)
  • Police in St. John's say cocaine seizures have become larger and more frequent. (cbc.ca)
  • Winbery S, Blaho K, Logan B, Geraci S. Multiple cocaine-induced seizures and corresponding cocaine and metabolite concentrations. (medscape.com)
  • Cocaine is a very addictive drug that is made from leaves of the coca plant found in South America. (medlineplus.gov)
  • In early 1986, the 42-year-old Massachusetts Democrat stood almost alone in the U.S. Senate demanding answers about the emerging evidence that CIA-backed Contras were filling their coffers by collaborating with drug traffickers then flooding U.S. borders with cocaine from South America. (salon.com)
  • Within the last ten years, frontier forests of Central America have become a strategic distribution center for drug traffickers transporting cocaine from South America into the United States. (uidaho.edu)
  • Another form of the drug is crack cocaine. (medlineplus.gov)
  • Crack cocaine has been heated to make it into a rock crystal. (medlineplus.gov)
  • Crack cocaine is smoked. (medlineplus.gov)
  • The high potency and relatively cheap cost of crack cocaine created another US cocaine epidemic. (medscape.com)
  • By the late 1970s, modifications in cocaine processing led to the development of freebase and crack cocaine. (medscape.com)
  • Crack cocaine is formed when the aqueous hydrochloride salt is mixed with baking soda and then heated. (medscape.com)
  • We hypothesize that crack cocaine is independently associated with smear-positive tuberculosis (TB). (cdc.gov)
  • In a case-control study of TB in London, 19 (86%) of 22 crack cocaine users with pulmonary TB were smear positive compared with 302 (36%) of 833 non-drug users. (cdc.gov)
  • The United Kingdom has seen a substantial increase in the prevalence of drug use in the past decade, particularly crack cocaine use ( 2 ). (cdc.gov)
  • Numbers of crack cocaine users assessed while in police custody in London increased 3-fold from 1993 through 2003 ( 3 ). (cdc.gov)
  • Evidence to directly link risk for TB with crack cocaine use is lacking, although an association with tuberculin positivity has been shown. (cdc.gov)
  • Chest radiograph of a tuberculosis patient addicted to crack cocaine. (cdc.gov)
  • Habitually smoking crack cocaine causes pulmonary damage (crack lung) ( Figure ). (cdc.gov)
  • We hypothesize that crack cocaine use increases the risk for smear-positive pulmonary TB and that a component of this risk relates to lung damage caused by crack cocaine inhalation. (cdc.gov)
  • To test the hypothesis that smear positivity at diagnosis was associated with crack cocaine use, we used a multivariate model with backwards elimination to exclude variables that did not make a significant contribution to the model. (cdc.gov)
  • TB patients who used crack cocaine were predominantly 20-49 years of age. (cdc.gov)
  • Crack cocaine users and other drug users were significantly more likely than non-drug users to have been born in the United Kingdom, of white or black Caribbean ethnic origin, homeless, alcohol abusers, or have a history of imprisonment. (cdc.gov)
  • It can also then be turned into free base form (typically crack cocaine), in which it can be heated until sublimated and then the vapours can be inhaled. (wikipedia.org)
  • A Staffordshire Bull Terrier that mauled its owner to death after being filmed by the BBC had eaten crack cocaine, an inquest has heard. (yahoo.com)
  • There are three types of cocaine: coke, crack and freebase. (talktofrank.com)
  • Cocaine powder has a bitter 'chemical' taste and smell, while crack cocaine can smell like burnt plastic or rubber. (talktofrank.com)
  • Powdered coke and crack can be prepared to make a solution for injecting, which is much more dangerous than snorting or smoking cocaine. (talktofrank.com)
  • When snorted, cocaine can take from around 5 to 30 minutes to kick in, whereas the effects of smoking crack are almost instant. (talktofrank.com)
  • Harzke AJ, Williams ML, Bowen AM. Binge Use of Crack Cocaine and Sexual Risk Behaviors Among African-American, HIV-Positive Users. (medscape.com)
  • Levamisole poisoning is more likely to affect women, and more likely to occur when the cocaine was smoked in crack form. (nymag.com)
  • Gold MS. Cocaine (and crack): clinical aspects. (medscape.com)
  • Availability of highly biologically active forms, such as crack cocaine , has worsened the problem of cocaine dependence. (msdmanuals.com)
  • The resultant precipitate (crack cocaine ) is volatilized by heating (it is not burned) and inhaled. (msdmanuals.com)
  • Have you ever used cocaine, including crack or freebase, or other street drugs? (cdc.gov)
  • In the past 12 months, how many days have you used cocaine, including crack or freebase, or other street drugs? (cdc.gov)
  • Some people use cocaine along with other drugs or alcohol. (medlineplus.gov)
  • New York (MedscapeWire) Jun 29 - Scientists have found that cocaine abuse coupled with use of alcohol leads to more impulsive decision-making and to poorer performance on tests of learning and memory than does use of either cocaine or alcohol alone. (medscape.com)
  • Jean Lud Cadet, MD, of NIDA's Intramural Research Program in Baltimore, Maryland, and Karen Bolla, PhD, of Johns Hopkins Medical Institutions in Baltimore, studied the interactive effects of cocaine and alcohol in 56 adult cocaine abusers. (medscape.com)
  • All participants abstained from both cocaine and alcohol during the 4-week study. (medscape.com)
  • The results of this study support the view that cocaine abuse can have a major negative impact on the brain and these effects are compounded by the concurrent use of alcohol," explained Dr. Cadet. (medscape.com)
  • Children and adolescents rarely experiment with an illicit drug such as cocaine prior to trying alcohol and cigarettes. (medscape.com)
  • The risk of overdose increases if you mix cocaine with other drugs or alcohol. (talktofrank.com)
  • The L.A. County Medical Examiner's Office just released its findings -- and according to the document, obtained by TMZ, the autopsy and toxicology found a deadly combo of alcohol, cocaine and fentanyl. (tmz.com)
  • She also had toxic levels of cocaine and alcohol in her system. (tmz.com)
  • He accepted that to some extent his actions were caused by his use of alcohol and cocaine. (itv.com)
  • So far, most cases of serious illness have been identified in the San Francisco area, where 90 percent of cocaine users tested were found to have the drug in their system, but there's plenty of reason to think it's everywhere. (nymag.com)
  • In 2020, 25 percent of cocaine users in Europe were using the drug daily, while 37 percent took cocaine between two and six days in a week. (statista.com)
  • FEBRUARY 16--Presidential contender Donald Trump, who has vowed to stanch the flow of narcotics and criminals entering the U.S. from Mexico, once wrote to a judge urging leniency for a friend who was convicted of distributing kilos of cocaine that had been smuggled into the country from Colombia, court records show. (thesmokinggun.com)
  • Cocaine is a stimulant that can make people feel like they have more energy and are extra alert. (medlineplus.gov)
  • Cocaine (from French: cocaïne, from Spanish: coca, ultimately from Quechua: kúka) is a tropane alkaloid that acts as a central nervous system (CNS) stimulant. (wikipedia.org)
  • Cocaine is a sympathomimetic drug with central nervous system stimulant and euphoriant properties. (msdmanuals.com)
  • If someone who is dependent on cocaine stops using it, they will have withdrawal symptoms. (medlineplus.gov)
  • Addicts who abstain from cocaine may experience craving and drug withdrawal symptoms, with depression, decreased libido, decreased ability to feel pleasure, and fatigue being most common. (wikipedia.org)
  • And curiously, one study found that people given propranolol while undergoing cocaine withdrawal had better verbal recall, suggesting that the drug indeed affects memory only selectively. (time.com)
  • Withdrawal manifests primarily as depression, difficulty concentrating, and somnolence ( cocaine washout syndrome). (msdmanuals.com)
  • Tolerance to cocaine occurs, and withdrawal from heavy use is characterized by somnolence, difficulty concentrating, increased appetite, and depression. (msdmanuals.com)
  • Overdose deaths involving cocaine and psychostimulants continue to increase. (cdc.gov)
  • From 2016 to 2017, death rates involving cocaine and psychostimulants increased across age groups, racial/ethnic groups, county urbanization levels, and multiple states. (cdc.gov)
  • Death rates involving cocaine and psychostimulants, with and without opioids, have increased. (cdc.gov)
  • Drug overdose deaths involving cocaine, psychostimulants with abuse potential (psychostimulants), or both substances combined increased 42.4% from 12,122 in 2015 to 17,258 in 2016. (cdc.gov)
  • CDC analyzed 2016-2017 changes in age-adjusted death rates involving cocaine and psychostimulants by demographic characteristics, urbanization levels, U.S. Census region, 34 states, and the District of Columbia (DC). (cdc.gov)
  • Provisional data from 2018 indicate that deaths involving cocaine and psychostimulants are continuing to increase. (cdc.gov)
  • Increased surveillance and evidence-based multisectoral prevention and response strategies are needed to address deaths involving cocaine and psychostimulants and opioids. (cdc.gov)
  • In 2021, the U.S. age-adjusted drug overdose death rate involving cocaine was 7.3 deaths per 100,000 standard population. (cdc.gov)
  • Drug overdose deaths involving cocaine were identified using International Classification of Diseases, Tenth Revision underlying cause-of-death codes X40-X44, X60-X64, X85, and Y10-Y14 with a multiple cause-of-death code T40.5. (cdc.gov)
  • This increased neural response to cocaine-associated images among cocaine users is what we expected," Dunning said. (sciencedaily.com)
  • It suggests that cocaine stimuli are similar to other emotional stimuli in increasing motivated attention among cocaine users. (sciencedaily.com)
  • Cocaine abuse can cause paranoia, although that reaction appears to be infrequent among cocaine users as a whole. (tsn.ca)
  • In addition to his 1986 plea to federal cocaine distribution and income tax charges, Weichselbaum's rap sheet included prior convictions for grand theft auto and the embezzlement of more than $130,000 from a Brooklyn manufacturing firm where he worked for a decade. (thesmokinggun.com)
  • One of the big news stories today was the indictment of Rudy Giuliani's now-former South Carolina campaign chairman Thomas Ravenel, the state's now-suspended Treasurer, on federal cocaine distribution charges. (stopthedrugwar.org)
  • People snort cocaine powder through the nose or rub it into their gums. (medlineplus.gov)
  • If you snort a gram of cocaine, you are destroying 4m square of rainforest and that rainforest is not just Colombian-it belongs to all of us who live on this planet, so we should all be worried about it. (motherjones.com)
  • Most people snort cocaine - they crush it into a fine powder, divide it into lines and snort it through the nose. (talktofrank.com)
  • During 2015-2016, age-adjusted cocaine-involved and psychostimulant-involved death rates increased by 52.4% and 33.3%, respectively. (cdc.gov)
  • From 2015 to 2016, cocaine-involved and psychostimulant-involved death rates increased 52.4% and 33.3%, respectively ( 1 ). (cdc.gov)
  • Age-adjusted death rates †† were examined for the period 2016- 2017 for cocaine and psychostimulants. (cdc.gov)
  • Can a person overdose on cocaine? (medlineplus.gov)
  • It's possible to overdose on cocaine. (medlineplus.gov)
  • In 2017, opioids were involved in 72.7% and 50.4% of cocaine-involved and psychostimulant-involved overdoses, respectively, and the data suggest that increases in cocaine-involved overdose deaths from 2012 to 2017 were driven primarily by synthetic opioids. (cdc.gov)
  • Although some absorption and systemic effects may occur, the use of cocaine as a topical anesthetic and vasoconstrictor is generally safe, rarely causing cardiovascular toxicity, glaucoma, and pupil dilation. (wikipedia.org)
  • After an introduction the reader will be guided towards medical aspects of addictive disorders, where history, toxicity, manifestations of toxicity and the mechanisms of action of cocaine are explained. (bvsalud.org)
  • Darke S, Kaye S, Duflou J. Comparative cardiac pathology among deaths due to cocaine toxicity, opioid toxicity and non-drug-related causes. (medscape.com)
  • Fatal excited delirium following cocaine use: epidemiologic findings provide new evidence for mechanisms of cocaine toxicity. (medscape.com)
  • Elaborate levels of cocaine production, smuggling, and distribution have challenged efforts to diminish supply. (medscape.com)
  • However, those who had consumed cocaine that also contained a high level of levamisole showed even greater impairment in their executive functions than those who consumed cocaine with lower levels of levamisole, even though the amount of cocaine they had taken was the same. (eurekalert.org)
  • The level of violence that's out there, the level of drug usage that's out there, the level of needle usage that's out there, the amount of cocaine that people are putting up their nose, OxyContin they are putting in their arms - the crimes that they are committing to get the money to be able to buy these drugs - it would blow your mind,' Hogan said in an interview. (cbc.ca)
  • Several years ago there was a report that cocaine had been found in one of the ships that belonged to James Chao's company. (wral.com)
  • Some report that cocaine use can also cause irritability and anxiety in users, especially at the end of a period of intoxication. (tsn.ca)
  • A family history of substance abuse may be a risk factor for early cocaine use and for rapid dependence on cocaine. (medscape.com)
  • Pharmacotherapeutics directed at deficiencies associated with cocaine dependence: focus on dopamine, norepinephrine and glutamate. (medscape.com)
  • Snorting cocaine can damage your nose, especially if it's not been chopped very finely. (talktofrank.com)
  • Cocaine can be detected in a urine test for up to 3 days after snorting it. (talktofrank.com)
  • Over time, snorting cocaine damages the cartilage in your nose that separates your nostrils. (talktofrank.com)
  • Injecting cocaine also puts a person at higher risk of getting diseases such as HIV and hepatitis C . (medlineplus.gov)
  • Injecting cocaine can damage veins and cause ulcers and gangrene. (talktofrank.com)
  • Cocaine is only one type of illegal drug that can be injected in the body through many ways (e.g. smoking, sniffing and injecting). (bvsalud.org)
  • The 43-year-old pleaded guilty to charges she sold cocaine at her home and on Water Street in Augusta. (sunjournal.com)
  • People who regularly take cocaine cut with the animal anti-worming agent levamisole demonstrate impaired cognitive performance and a thinned prefrontal cortex. (eurekalert.org)
  • This is the most common way to take cocaine. (talktofrank.com)
  • 1 Little use was made of it in Europe, however, until 1883, when a German army physician, Dr. Theodor Aschenbrandt, secured a supply of pure cocaine from the pharmaceutical firm of Merck and issued it to Bavarian soldiers during their autumn maneuvers. (druglibrary.org)
  • Based on this, they examined the cognitive performance of those who had taken cocaine with a high levamisole content (more than 25% proportional to the cocaine) and those who had taken cocaine with a low levamisole content (less than 25%), and compared the results with a control group who had not taken cocaine. (eurekalert.org)
  • They become very excited and agitated, it is highly more likely that this attack happened because this dog had taken cocaine. (yahoo.com)
  • Synthetic opioids appear to be the primary driver of cocaine-involved death rate increases, and recent data point to increasing synthetic opioid involvement in psychostimulant-involved deaths. (cdc.gov)
  • Use of cocaine increases the overall risk of death, and intravenous use potentially increases the risk of trauma and infectious diseases such as blood infections and HIV through the use of shared paraphernalia for use. (wikipedia.org)
  • CDC also examined trends in age-adjusted cocaine-involved and psychostimulant-involved death rates from 2003 to 2017 overall, as well as with and without co-involvement of opioids. (cdc.gov)
  • In 2017, the Global Burden of Disease study found that cocaine use caused around 7,300 deaths annually. (wikipedia.org)
  • Cocaine is the second-most commonly consumed illegal substance worldwide after cannabis. (eurekalert.org)
  • Upon asking what she was going to have at her party, she informed me that a keg would be purchased, and that a limited amount of cannabis and cocaine would be available for 'a select few. (erowid.org)
  • The police found cannabis and cocaine, electronic scales and other items used in the trafficking of dangerous drugs during the raids, as well as fake euro notes and a 0.25 caliber, unlicenced weapon. (timesofmalta.com)
  • The 29-year-old is to be charged with trafficking and possession of cocaine, heroin, and cannabis, grievously injuring third persons, and being in possession of a firearm without a police licence. (timesofmalta.com)
  • Around 10 years ago, however, a new adulterant made an appearance which is now widely spread in street cocaine in Europe and North America: The animal anti-worming agent levamisole. (eurekalert.org)
  • It's not fully understood why levamisole is added to cocaine, but it is assumed that it may increase or prolong the effects of cocaine. (eurekalert.org)
  • In order to estimate the consumption of cocaine and the amount of levamisole content, the scientists analyzed hair samples of their study participants. (eurekalert.org)
  • In a second, independent study, the researchers used magnetic resonance imaging (MRI) to find out whether there was also a difference in the brain anatomy of people who consumed cocaine containing a higher or lower proportion of levamisole. (eurekalert.org)
  • The same effect was seen in this study: People who consumed cocaine with a high levamisole content clearly displayed a thinner prefrontal cortex - the area of the brain associated with executive functions. (eurekalert.org)
  • For research leader Boris Quednow, the functional and structural changes observed in the brain clearly indicate that levamisole could have a toxic effect on the brain for cocaine users. (eurekalert.org)
  • We can assume from our findings that it is not just cocaine that changes the brain, but that the adulterant levamisole has an additional harmful effect. (eurekalert.org)
  • The sorts of cognitive impairment often exhibited by cocaine users may therefore be exacerbated by levamisole. (eurekalert.org)
  • Such programs mean users can have their drugs tested for purity and therefore avoid taking cocaine that has very high levels of levamisole," says Quednow. (eurekalert.org)
  • Cutaneous vasculopathy and neutropenia associated with levamisole-adulterated cocaine. (medscape.com)
  • Complications associated with use of levamisole-contaminated cocaine: an emerging public health challenge. (medscape.com)
  • Agranulocytosis after consumption of cocaine adulterated with levamisole. (medscape.com)
  • Observations regarding levamisole in the cocaine supply. (medscape.com)
  • The chief active ingredient in coca leaves, the alkaloid cocaine, was isolated in pure form in 1844. (druglibrary.org)
  • Cocaine , an alkaloid present in the leaves of the coca plant, enhances norepinephrine , dopamine , and serotonin activity in the central and peripheral nervous systems by blocking the reuptake of biogenic amines. (msdmanuals.com)
  • Recreational and fashionable use brought increasing reports of cocaine-related morbidities and several fatalities. (medscape.com)
  • Since 1961, the Single Convention on Narcotic Drugs has required countries to make recreational use of cocaine a crime. (wikipedia.org)
  • Fehr said his discussions with players are confidential and noted that players would have to agree to alter their collective bargaining agreement with the NHL before the league could begin testing all urine samples for cocaine or other recreational drugs. (tsn.ca)
  • Most cocaine users are episodic recreational users. (msdmanuals.com)
  • In our opinion the dogs behaviour was as a result of the intoxication of cocaine. (yahoo.com)
  • Are casual users of cocaine really responsible for pervasive environmental destruction? (motherjones.com)
  • While it's true that in the last five years , production of cocaine in Bolivia , Colombia, and Peru has increased almost 20 percent, the truth is that the destruction of the rainforest is not due to increased demand from wealthy British cocaine users. (motherjones.com)
  • As expected, the cocaine users showed lower performance than non-users in all areas - attention, working memory, long-term memory, and executive functions. (eurekalert.org)
  • Scientists have conducted the most comprehensive study to date of how cocaine users respond to drug-related and other emotional stimuli, making use of comparisons with a matched control group and exploring the effects of recent cocaine use and abstinence. (sciencedaily.com)
  • Scientists at the U.S. Department of Energy's Brookhaven National Laboratory and Stony Brook University (SBU) have conducted the most comprehensive study to date of how cocaine users respond to drug-related and other emotional stimuli, making use of comparisons with a matched control group and exploring the effects of recent cocaine use and abstinence. (sciencedaily.com)
  • Using measures of brain activity over time, the scientists found that images depicting cocaine use immediately captured motivated attention among both active and abstinent cocaine users -- similar to the way other pleasant and unpleasant emotional images captured their attention compared with less evocative neutral scenes. (sciencedaily.com)
  • But while abstinent cocaine users generally retained this heightened attentive engagement, those who had used cocaine within the past three days quickly lost their sensitivity, first to pleasant and then to drug-related and unpleasant evocative images -- all within a mere 2000 milliseconds. (sciencedaily.com)
  • But in the next time interval, only the cocaine-addicted individuals (both those who were abstinent and recent users) showed a heightened response to drug-related images, continuing to respond as they did to other pleasant and unpleasant evocative images, while healthy control subjects maintained elevated responses only to the pleasant and unpleasant images. (sciencedaily.com)
  • In the final time interval, 1000-2000 milliseconds, the scientists found that healthy controls remained responsive to pleasant and unpleasant images, while abstinent cocaine users continued to respond to pleasant and drug-related images at a heightened level. (sciencedaily.com)
  • This latest time interval reflects sustained processing and encoding of information," Goldstein said, "so our findings may indicate an impaired ability for sustained processing of all emotional stimuli -- pleasant, unpleasant, and drug-related -- among the recent cocaine users. (sciencedaily.com)
  • This difficulty in sustaining motivated attention to emotional stimuli could potentially predispose cocaine users to compulsive drug use as a compensatory mechanism for their blunted response, she said. (sciencedaily.com)
  • A report came out today that could (and probably should) affect the New Year's Eve "skiing" plans of many a Craigslister this year: It seems that most of the cocaine in this country is now stepped on with a deworming drug meant for horses and other animals that is causing catastrophic illness in some users. (nymag.com)
  • Cardiac arrest in cocaine users. (medscape.com)
  • Because cocaine is such a short-acting drug, heavy users may inject it or smoke it repeatedly every 10 to 15 minutes. (msdmanuals.com)
  • Learn about the dangerous and addictive traits of the drug cocaine. (icra.org)
  • In this article an elaboration will be made on the etiology, mechanisms of action and treatment of cocaine addictive disorder by unraveling its impacts on society and the human body. (bvsalud.org)
  • The drug cocaine will be used as a role model for explaining addictive disorders. (bvsalud.org)
  • Amin M, Gabelman G, Karpel J, Buttrick P. Acute myocardial infarction and chest pain syndromes after cocaine use. (medscape.com)
  • McCord J, Jneid H, Hollander JE, de Lemos JA, Cercek B, Hsue P. Management of cocaine-associated chest pain and myocardial infarction: a scientific statement from the American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology. (medscape.com)
  • Qureshi AI, Suri MF, Guterman LR, Hopkins LN. Cocaine use and the likelihood of nonfatal myocardial infarction and stroke: data from the Third National Health and Nutrition Examination Survey. (medscape.com)
  • The US Customs and Border Protection found the cocaine worth $1.8 million aboard a fishing boat near Miami River. (ybw.com)
  • The captain and first officer of an ocean going tug boat are now starting lengthy prison sentences after being found guilty of trafficking £512 million worth of cocaine. (ybw.com)
  • Officials say that during the secondary inspection, they found the cocaine in five packages within the seat cushion. (foxnews.com)
  • What are the treatments for cocaine use disorder? (medlineplus.gov)
  • The treatments for cocaine use disorder are different types of behavioral therapies. (medlineplus.gov)
  • The relation between cocaine and Anti-Social Personality Disorder are unraveled followed by issues such as priming, stress and relapse. (bvsalud.org)
  • As is common practice, TSA notified the San Jose Police Department (Airport Division) of the discovery, who responded and took possession of the cocaine," Feinstein said. (cnn.com)
  • Prospective multicenter evaluation of cocaine-associated chest pain. (medscape.com)
  • Cocaine Associated Chest Pain (COCHPA) Study Group. (medscape.com)
  • Chest pain associated with cocaine: an assessment of prevalence in suburban and urban emergency departments. (medscape.com)
  • CBP officials say the cocaine has an estimated street value of more than $65,000. (foxnews.com)
  • Cocaine has trumped other drugs in the city's growing illicit trade, RCMP and Royal Newfoundland Constabulary investigators told CBC News. (cbc.ca)
  • Parry, Robert, FOOLING AMERICA, New York, William Morrow and Company, 1992 Several sections discuss Contra cocaine smuggling in this book which describes how Washington insiders twist the truth and manufacture the Conventional Wisdom. (whale.to)
  • Karen Grigsby Bates reviews The Cocaine Chronicles , an anthology of short stories about the impact of cocaine on America. (npr.org)
  • Nicholas Carmichael, an expert in veterinary toxicology, told the hearing that samples of cocaine and morphine had been discovered in Major's urine. (yahoo.com)
  • In addition to taking cocaine himself, Freud offered some to his friend and associate, Dr. Ernst von Fleischl-Marxow, who was suffering from an exceedingly painful disease of the nervous system (which was later to prove fatal), and who was addicted to morphine. (druglibrary.org)
  • What are the short-term effects of cocaine? (medlineplus.gov)
  • Other long-term effects of cocaine use may include malnutrition and movement disorders , including Parkinson's disease . (medlineplus.gov)
  • Cocaine also blocks the serotonin transporter and norepinephrine transporter, inhibiting reuptake of serotonin and norepinephrine from the synaptic cleft into the pre-synaptic axon terminal and increasing activation of serotonin receptors and norepinephrine receptors in the post-synaptic neuron, contributing to the mental and physical effects of cocaine exposure. (wikipedia.org)
  • A team of researchers from the Psychiatric Hospital and the Institute of Forensic Medicine of the University of Zurich have now researched the extent to which the common cutting agent impairs the cognitive performance and alters the brain structure of people who consume it, thereby increasing the well-described negative effects of cocaine on the brain. (eurekalert.org)
  • Experts think cocaine-makers are using the drug as their go-to filler now because it has been shown to increase the effects of cocaine in animal studies (a theory which evokes the curious and fascinating concept of drug lords subscribing to medical journals). (nymag.com)
  • More to the point, Freud described in detail the effects of small doses of cocaine on his own depression. (druglibrary.org)
  • The mechanisms by which cocaine effects the body will be discussed in detail in the medical section of this article, first however, emphasis will be made upon the history of cocaine. (bvsalud.org)
  • Cocaine gives the individual a big burst of energy called euphoria, what can be the reason why it is so popular amongst certain groups. (bvsalud.org)
  • The anecdotal evidence shows the cheaper cocaine is being sold for 30 a gram, while "luxury" costs 50. (bbc.co.uk)
  • Zinc reduces the detection of cocaine, methamphetamine, and THC by ELISA urine testing. (medscape.com)
  • One-third of the 2,400 player urine samples collected each year are screened more closely for drugs of abuse, such as cocaine. (tsn.ca)