• Joslin Diabet
  • Another study at Joslin Diabetes Center in Boston is following people who have had Type 1 for over 50 years , to find out what keeps them complication-free, or close to it. (diabetesselfmanagement.com)
  • The study, conducted by the Joslin Diabetes Center on people who have lived with type 1 diabetes for more than 50 years, presents a strong case for the existence of a protective mechanism in some individuals that allows them to live relatively free of the problems typically associated with long-term duration of diabetes. (healthcanal.com)
  • If we can identify what constitutes this protective mechanism, we have the potential to induce such protections in others living with diabetes," said lead researcher George King, Chief Scientific Officer of the Joslin Diabetes Center and Professor of Medicine at Harvard Medical School. (healthcanal.com)
  • type
  • Before the discovery of insulin, this was the main cause of death for people with type 1 diabetes. (diabetesdaily.com)
  • DKA may happen to anyone with diabetes, though it is rare in people with type 2. (diabetesdaily.com)
  • Type 1 diabetes is complicated-and if you don't manage it properly, there are complications, both short-term and long-term. (endocrineweb.com)
  • Diabetic ketoacidosis (sometimes abbreviated to DKA) is sometimes the first indication that a person has type 1 diabetes, and can be a serious complication of lack of insulin. (endocrineweb.com)
  • By tightly controlling your blood glucose level (or your child's blood glucose level), you can avoid long-term complications of type 1 diabetes. (endocrineweb.com)
  • Most people with Type 2 diabetes suffer from the Insulin Resistance Syndrome (IRS), which can include insulin resistance, high blood sugar, abdominal obesity, high blood pressure and cholesterol problems. (diabetesnet.com)
  • A large population-based study of 124,503 adults in the UK who have Type 2 diabetes found that those who got a flu vaccine had a 24 percent lower death rate than those who didn't get vaccinated. (mendosa.com)
  • Pambianco said that guidelines for managing type 1 diabetes are often derived from what is known about treating type 2 disease. (redorbit.com)
  • People with type 1 diabetes who are older than 10 should start these visits within 3 to 5 years of diagnosis. (webmd.com)
  • If you have type 2 diabetes , make an appointment as soon as you're diagnosed. (webmd.com)
  • If you have type 2 diabetes and don't take care of yourself, a minor scratch could turn into a serious infection. (webmd.com)
  • Type 2 diabetes slows your body's ability to fight infection. (webmd.com)
  • Diabetes UK conducted the survey with over 2,500 adults affected by Type 2 diabetes. (diabetes.org.uk)
  • These results illustrate the everyday challenge facing those living with Type 2 diabetes," said Dr Marc Evans, Consultant Diabetologist in Cardiff. (diabetes.org.uk)
  • Type 2 diabetes is treated with lifestyle changes such as a healthier diet, weight loss where appropriate, and increased physical activity. (diabetes.org.uk)
  • The purpose of the study was "to call attention to the issue of diabetes-related complications and bring about change in the way type 2 diabetes is managed in the U.S. (medpagetoday.com)
  • Estimated annual health care costs for a person with type 2 diabetes and related complications are $10,000, about $1,600 of which is out-of-pocket. (medpagetoday.com)
  • Diabetic foot problems affect 22.9%, and diabetic eye disease affects 18.9% of people with type 2 diabetes. (medpagetoday.com)
  • And what about the 10% to 15% of people with Type 1 who never seem to get severe complications, without practicing intensive control? (diabetesselfmanagement.com)
  • On the Web site TuDiabetes, a reader with Type 1 asked, "I [have had diabetes for over 38 years] with no complications. (diabetesselfmanagement.com)
  • Foot wounds are the most common type of wound complication. (emaxhealth.com)
  • Researchers will focus on type 1 diabetes, the less common but unpreventable form of diabetes. (uofmhealth.org)
  • In type 1 diabetes, the body's immune system destroys the pancreatic beta cells responsible for making insulin, a hormone the body needs to convert food into energy. (uofmhealth.org)
  • Type 1 usually strikes children and young adults, compared to type 2 diabetes which is associated with older age, obesity and family history. (uofmhealth.org)
  • The EDC study is a representative ( 11 ) prospective type 1 diabetes cohort, now entering its 18th year of follow-up. (diabetesjournals.org)
  • Kuwaiti researchers say that periodontal disease severity is associated with both diabetes duration and the presence of diabetes complications in people with type 1. (diabeteshealth.com)
  • Twenty-nine patients with type 1 of less than five years duration were compared with 43 patients with greater than five years of diabetes duration. (diabeteshealth.com)
  • They both had type 2 diabetes and my days spent alone with them exposed me to their misunderstanding of how their diabetes really affected them. (diabeteshealth.com)
  • A decade later I married a type 1 person living with diabetes and experienced the full court of the diabetes spectrum with my type 2 family members and type 1 husband of almost 20 years. (diabeteshealth.com)
  • My grandmothers, the type 2 have struggled with their diabetes as long as I could remember. (diabeteshealth.com)
  • My former Type 1 husband was a role model in how to manage your diabetes, while my intelligent family members were role models on how an invisible disease can be misunderstood, devastating the quality of their life while leaving heart broken family members behind. (diabeteshealth.com)
  • Non-modifiable risk factors of diabetic complications are type of diabetes, age of onset, and genetic factors, both protective and predisposing have been found. (wikipedia.org)
  • However, (non-modifiable) risk factors such as age at diabetes onset, type of diabetes, gender and genetics play a role. (wikipedia.org)
  • Ketoacidosis is much more common in type 1 diabetes than type 2. (wikipedia.org)
  • Lethargy may ultimately progress to a coma, though this is more common in type 2 diabetes than type 1. (wikipedia.org)
  • It is more accurate to note that iatrogenic hypoglycemia is typically the result of the interplay of absolute (or relative) insulin excess and compromised glucose counterregulation in type 1 and advanced type 2 diabetes. (wikipedia.org)
  • A study in the United Kingdom known as the United Kingdom Prospective Diabetes Study (UKPDS), released in 1999, found similar results for people with type 2 diabetes. (wikipedia.org)
  • A total of 1,441 volunteers with type 1 diabetes were recruited from 29 medical centers in the United States and Canada between 1983 and 1989, and were followed up until 1993. (wikipedia.org)
  • Patients with type 2 diabetes were excluded from the study, as were those who had been diagnosed less than one year ago or more than 15 years before. (wikipedia.org)
  • chronic
  • There remains a critical need to better understand the underlying disease mechanisms responsible for diabetes complications in order to develop new and improved therapeutic strategies for these chronic conditions. (diabetesjournals.org)
  • Other health problems compound the chronic complications of diabetes such as smoking, obesity, high blood pressure, elevated cholesterol levels, and lack of regular exercise which are accessible to management as they are modifiable. (wikipedia.org)
  • severe
  • What's most interesting, Vinik points out, is that sRAGE (the circulating soluble receptor for AGEs) is deficient in those who have the most severe complications, and is present at high levels in those with the most longevity. (healthcanal.com)
  • patients
  • In fact, patients who were diagnosed with diabetes in the 1950s had a fivefold higher mortality rate than their peers who were diagnosed in the 1970s. (redorbit.com)
  • Can we identify patients at risk for developing complications? (diabetesjournals.org)
  • Asai called the use of topical simvastatin a "simple strategy that may have significant therapeutic potential for enhancing wound healing in patients with impaired microcirculation, such as that in diabetes. (emaxhealth.com)
  • For patients with [greater than] five years diabetes duration, periodontal disease severity was also greater in patients with one or more diabetes complications, as assessed by the number of missing teeth. (diabeteshealth.com)
  • cholesterol
  • Reducing fat and protein intake to the amount needed nutritionally, lowering elevated blood pressure, exercising , improving the diet in general, avoiding smoking, and controlling cholesterol levels have all shown benefits in reducing complications. (diabetesnet.com)
  • As someone with diabetes, your level of cholesterol should be tested once a year. (diabetes.co.uk)
  • Inflammatory processes in the liver lead to elevated cholesterol levels in people with diabetes, thus promoting subsequent vascular diseases. (eurekalert.org)
  • treatment
  • Fundamentally new approaches are needed to understand the metabolic abnormalities that lead to diabetic complications and develop effective treatment or prevention strategies," says Gardner, one of a nine-member research team on diabetes-related eye disease that was recruited to join Kellogg in 2010. (uofmhealth.org)
  • Prompt, proper treatment usually results in full recovery, though death can result from inadequate or delayed treatment, or from complications (e.g., brain edema). (wikipedia.org)
  • Aldose reductase inhibitor for treatment of diabetic complications. (wikipedia.org)
  • blood
  • The primary cause of complications is that higher levels of blood sugar cause your blood to become more acidic. (diabetesdaily.com)
  • Washington University researchers say that blood vessel damage in diabetes may involve a deficiency of fatty acid synthase (FAS) an enzyme that helps protect blood vessel walls. (diabetesselfmanagement.com)
  • Diabetes is also associated with narrow arteries, which makes it more difficult for blood to reach a wound and facilitate healing. (emaxhealth.com)
  • In an accompanying editorial, Dr. Aaron Vinik, Director, Eastern Virginia Medical School Diabetes Research Center, writes that "the accumulation of AGEs may be one of the important factors in metabolic memory," a phenomenon in which an initial period of good glycemic, lipid and blood pressure control results in a prolonged period of health benefits that last beyond the period of control. (healthcanal.com)
  • found
  • A summary of the miRNAs relevant to diabetes complications is found in Table 1 . (diabetesjournals.org)
  • Now a new study has found that application of a topical statin drug speeds up wound healing in mice with diabetes. (emaxhealth.com)
  • The study also found that those with high plasma carboxyethyl-lysine and pentosidine, or advanced glycation end products (AGEs), were 7.2 times more likely to have some kind of complication than those who had low levels of this combination of AGEs. (healthcanal.com)
  • raises
  • Thus, this study suggests that not all AGEs are alike in their actions and raises the exciting possibility that some AGEs may be markers for protection against one or more diabetic complications. (healthcanal.com)