• Joslin Diabet
  • Another study at Joslin Diabetes Center in Boston is following people who have had Type 1 for over 50 years , to find out what keeps them complication-free, or close to it. (diabetesselfmanagement.com)
  • The study, conducted by the Joslin Diabetes Center on people who have lived with type 1 diabetes for more than 50 years, presents a strong case for the existence of a protective mechanism in some individuals that allows them to live relatively free of the problems typically associated with long-term duration of diabetes. (healthcanal.com)
  • If we can identify what constitutes this protective mechanism, we have the potential to induce such protections in others living with diabetes," said lead researcher George King, Chief Scientific Officer of the Joslin Diabetes Center and Professor of Medicine at Harvard Medical School. (healthcanal.com)
  • obesity
  • Most people with Type 2 diabetes suffer from the Insulin Resistance Syndrome (IRS), which can include insulin resistance, high blood sugar, abdominal obesity, high blood pressure and cholesterol problems. (diabetesnet.com)
  • Type 1 usually strikes children and young adults, compared to type 2 diabetes which is associated with older age, obesity and family history. (uofmhealth.org)
  • Other health problems compound the chronic complications of diabetes such as smoking, obesity, high blood pressure, elevated cholesterol levels, and lack of regular exercise which are accessible to management as they are modifiable. (wikipedia.org)
  • type
  • DKA may happen to anyone with diabetes, though it is rare in people with type 2. (diabetesdaily.com)
  • Type 1 diabetes is complicated-and if you don't manage it properly, there are complications, both short-term and long-term. (endocrineweb.com)
  • Diabetic ketoacidosis (sometimes abbreviated to DKA) is sometimes the first indication that a person has type 1 diabetes, and can be a serious complication of lack of insulin. (endocrineweb.com)
  • By tightly controlling your blood glucose level (or your child's blood glucose level), you can avoid long-term complications of type 1 diabetes. (endocrineweb.com)
  • Measurable kidney damage is found in 43 percent of Type 1 diabetics who have had their disease longer than five years and in 25 percent of those with Type 2 diabetes for 12 years. (diabetesnet.com)
  • Pambianco said that guidelines for managing type 1 diabetes are often derived from what is known about treating type 2 disease. (redorbit.com)
  • If you have type 2 diabetes , make an appointment as soon as you're diagnosed. (webmd.com)
  • If you have type 2 diabetes and don't take care of yourself, a minor scratch could turn into a serious infection. (webmd.com)
  • Type 2 diabetes slows your body's ability to fight infection. (webmd.com)
  • Diabetes UK conducted the survey with over 2,500 adults affected by Type 2 diabetes. (diabetes.org.uk)
  • These results illustrate the everyday challenge facing those living with Type 2 diabetes," said Dr Marc Evans, Consultant Diabetologist in Cardiff. (diabetes.org.uk)
  • Type 2 diabetes is treated with lifestyle changes such as a healthier diet, weight loss where appropriate, and increased physical activity. (diabetes.org.uk)
  • And what about the 10% to 15% of people with Type 1 who never seem to get severe complications, without practicing intensive control? (diabetesselfmanagement.com)
  • On the Web site TuDiabetes, a reader with Type 1 asked, "I [have had diabetes for over 38 years] with no complications. (diabetesselfmanagement.com)
  • Foot wounds are the most common type of wound complication. (emaxhealth.com)
  • To date, no attempt has been made to systemically understand the energy metabolism abnormalities in these tissues in type 1 diabetes, or to link these abnormalities to complications progressions," says study principal investigator and kidney specialist Frank C. Brosius III, M.D., chief of the U-M Department of Nephrology . (uofmhealth.org)
  • Researchers will focus on type 1 diabetes, the less common but unpreventable form of diabetes. (uofmhealth.org)
  • In type 1 diabetes, the body's immune system destroys the pancreatic beta cells responsible for making insulin, a hormone the body needs to convert food into energy. (uofmhealth.org)
  • It's important to note that most of the people in this study developed type 1 diabetes before strict glycemic control was even possible or used as the standard of medical care, the researchers write. (healthcanal.com)
  • Kuwaiti researchers say that periodontal disease severity is associated with both diabetes duration and the presence of diabetes complications in people with type 1. (diabeteshealth.com)
  • Twenty-nine patients with type 1 of less than five years duration were compared with 43 patients with greater than five years of diabetes duration. (diabeteshealth.com)
  • They both had type 2 diabetes and my days spent alone with them exposed me to their misunderstanding of how their diabetes really affected them. (diabeteshealth.com)
  • A decade later I married a type 1 person living with diabetes and experienced the full court of the diabetes spectrum with my type 2 family members and type 1 husband of almost 20 years. (diabeteshealth.com)
  • My grandmothers, the type 2 have struggled with their diabetes as long as I could remember. (diabeteshealth.com)
  • My former Type 1 husband was a role model in how to manage your diabetes, while my intelligent family members were role models on how an invisible disease can be misunderstood, devastating the quality of their life while leaving heart broken family members behind. (diabeteshealth.com)
  • When people experience stress, they oftentimes do things that are not ideal for effective glucose management," says Mark Heyman, Ph.D., a clinical psychologist in San Diego who specializes in diabetes and also has type 1 diabetes. (diabeticlivingonline.com)
  • Type 1 diabetes has an enormous impact on the quality of life for the ~140,000 people in Australia with this disease. (garvan.org.au)
  • In Australia type 1 diabetes is increasing at an annual rate of ~3%, a trend also seen worldwide. (garvan.org.au)
  • There is no cure for type 1 diabetes. (garvan.org.au)
  • At Garvan, Associate Professor Shane T. Grey and his team are studying the genes that contribute to type 1 diabetes at the functional level. (garvan.org.au)
  • This may also lead to new prognostic markers and drug targets to treat type 1 diabetes. (garvan.org.au)
  • This lets A/Prof Grey's team fill a significant scientific gap: to be the first in the world to look at key genes and mutations that lead to complications in type 1 diabetes. (garvan.org.au)
  • Why we use genomics for studying type 1 diabetes . (garvan.org.au)
  • Non-modifiable risk factors of diabetic complications are type of diabetes, age of onset, and genetic factors, both protective and predisposing have been found. (wikipedia.org)
  • However, (non-modifiable) risk factors such as age at diabetes onset, type of diabetes, gender and genetics play a role. (wikipedia.org)
  • Ketoacidosis is much more common in type 1 diabetes than type 2. (wikipedia.org)
  • Lethargy may ultimately progress to a coma, though this is more common in type 2 diabetes than type 1. (wikipedia.org)
  • It is more accurate to note that iatrogenic hypoglycemia is typically the result of the interplay of absolute (or relative) insulin excess and compromised glucose counterregulation in type 1 and advanced type 2 diabetes. (wikipedia.org)
  • A study in the United Kingdom known as the United Kingdom Prospective Diabetes Study (UKPDS), released in 1999, found similar results for people with type 2 diabetes. (wikipedia.org)
  • A total of 1,441 volunteers with type 1 diabetes were recruited from 29 medical centers in the United States and Canada between 1983 and 1989, and were followed up until 1993. (wikipedia.org)
  • Patients with type 2 diabetes were excluded from the study, as were those who had been diagnosed less than one year ago or more than 15 years before. (wikipedia.org)
  • DCCT
  • The DCCT provided quantifiable justification to healthcare providers that the additional expenses associated with intensive glycemic control and close monitoring of diabetes are cost effective. (wikipedia.org)
  • patients
  • In fact, patients who were diagnosed with diabetes in the 1950s had a fivefold higher mortality rate than their peers who were diagnosed in the 1970s. (redorbit.com)
  • Can we identify patients at risk for developing complications? (diabetesjournals.org)
  • Asai called the use of topical simvastatin a "simple strategy that may have significant therapeutic potential for enhancing wound healing in patients with impaired microcirculation, such as that in diabetes. (emaxhealth.com)
  • Diabetic peripheral neuropathy is one of the most common complications of diabetes and occurs over time in approximately 60 percent of all patients with diabetes. (uofmhealth.org)
  • Our goal is to make this obsolete - to find ways so that patients can retain kidney function, integrity of nerves and keep their vision - in spite of diabetes. (uofmhealth.org)
  • For patients with [greater than] five years diabetes duration, periodontal disease severity was also greater in patients with one or more diabetes complications, as assessed by the number of missing teeth. (diabeteshealth.com)
  • Adults with diabetes are two to four times more likely to have heart disease than nondiabetic people, and at least 65% of these patients will die from their heart disease. (sharecare.com)
  • severe
  • What's most interesting, Vinik points out, is that sRAGE (the circulating soluble receptor for AGEs) is deficient in those who have the most severe complications, and is present at high levels in those with the most longevity. (healthcanal.com)
  • Overall, complications are far less common and less severe in people with well-controlled blood sugar levels. (wikipedia.org)
  • clinical
  • Find the latest treatment for an existing complication in these Clinical Trials . (diabetesnet.com)
  • Diabetes Care , published by the American Diabetes Association, is the leading peer-reviewed journal of clinical research into one of the nation's leading causes of death by disease. (healthcanal.com)
  • In this video, Ronald Tamler, MD, clinical director of the Mount Sinai Diabetes Center, discusses the connection between the two diseases. (sharecare.com)
  • treatment
  • Fundamentally new approaches are needed to understand the metabolic abnormalities that lead to diabetic complications and develop effective treatment or prevention strategies," says Gardner, one of a nine-member research team on diabetes-related eye disease that was recruited to join Kellogg in 2010. (uofmhealth.org)
  • Prompt, proper treatment usually results in full recovery, though death can result from inadequate or delayed treatment, or from complications (e.g., brain edema). (wikipedia.org)
  • Changes were subsequently made in the eligibility criteria for the full-scale trial to exclude anyone with this very common short-term complication of diabetes treatment, which also raises questions about exactly how "random" the selection process really was. (wikipedia.org)
  • Aldose reductase inhibitor for treatment of diabetic complications. (wikipedia.org)
  • raises
  • Thus, this study suggests that not all AGEs are alike in their actions and raises the exciting possibility that some AGEs may be markers for protection against one or more diabetic complications. (healthcanal.com)
  • blood
  • The primary cause of complications is that higher levels of blood sugar cause your blood to become more acidic. (diabetesdaily.com)
  • Reducing fat and protein intake to the amount needed nutritionally, lowering elevated blood pressure, exercising , improving the diet in general, avoiding smoking, and controlling cholesterol levels have all shown benefits in reducing complications. (diabetesnet.com)
  • Washington University researchers say that blood vessel damage in diabetes may involve a deficiency of fatty acid synthase (FAS) an enzyme that helps protect blood vessel walls. (diabetesselfmanagement.com)
  • Diabetes is also associated with narrow arteries, which makes it more difficult for blood to reach a wound and facilitate healing. (emaxhealth.com)
  • In an accompanying editorial, Dr. Aaron Vinik, Director, Eastern Virginia Medical School Diabetes Research Center, writes that "the accumulation of AGEs may be one of the important factors in metabolic memory," a phenomenon in which an initial period of good glycemic, lipid and blood pressure control results in a prolonged period of health benefits that last beyond the period of control. (healthcanal.com)
  • Managing stress is the close cousin of managing diabetes because stress can have serious effects on your blood sugar. (diabeticlivingonline.com)