AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceNamed GroupsHealth CareGeographicals
Cardiovascular DiseasesDiabetes MellitusDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Age FactorsRisk FactorsDiabetes ComplicationsDiabetes Mellitus, ExperimentalBlood GlucoseBiological MarkersCohort StudiesHypertensionDiabetes, GestationalHemoglobin A, GlycosylatedProspective StudiesObesityHypoglycemic AgentsAtherosclerosisPrevalenceInsulinFollow-Up StudiesRisk AssessmentCross-Sectional StudiesBlood PressureBody Mass IndexMetabolic Syndrome XIncidenceUnited StatesTime FactorsDisease Models, AnimalInflammationInsulin ResistanceLipidsSex FactorsDyslipidemiasProportional Hazards ModelsC-Reactive ProteinCase-Control StudiesLife StyleHyperglycemiaCholesterolDiabetes InsipidusDiabetic NephropathiesDisease ProgressionSmokingDietRiskTreatment OutcomeCoronary DiseaseCholesterol, HDLCholesterol, LDLPredictive Value of TestsKidney Failure, ChronicTriglyceridesGenetic Predisposition to DiseaseGlucose Tolerance TestAlbuminuriaOxidative StressEndothelium, VascularCause of DeathAgingChronic DiseaseVascular DiseasesLongitudinal StudiesHyperlipidemiasStrokeComorbidityCalcinosisReference ValuesPrediabetic StateQuestionnairesMultivariate AnalysisJapanRegression AnalysisMice, Inbred NODHomocysteinePrimary PreventionArteriosclerosisIslets of LangerhansRetrospective StudiesKidney DiseasesHypolipidemic AgentsOdds RatioMyocardial InfarctionFastingGenotypeCoronary Artery DiseaseSeverity of Illness IndexGlucose IntoleranceHypercholesterolemiaExerciseDiabetic RetinopathySex DistributionLogistic ModelsAntihypertensive AgentsPrognosisHydroxymethylglutaryl-CoA Reductase InhibitorsPhenotypeCardiovascular SystemAntioxidants
ObesityHypertensionCoronaryIncidenceStrokeChronic respiratory diseasesRespiratoryMellitusManaging cardiovascular riskCancersAtherosclerosisOutcomesEpidemiologyAdultsPrimary Prevention of Cardiovascular DiseasePrevention and control of noncommunicable diseasesInflammationDisordersCause of mortalityCohortsMetabolismGeneticMetabolicAdverse cardiovascular eventsDevelopment of cardiovascularPrevalentMorbidity and mortaTypeIncreasesPeripheralOverall cardiovascularGlucoseMiddle-agedPatients2019Life expectancyIndividuals aged 30LipoproteinAffectsGestational diabetesNephropathyAcuteDiabeticOnsetNoncommunicablePaediatric diabetesDegenerativePhysiologicalPrematureInflammatoryInfectious diseasesInterventionYearsMortality riskHeart disease
Obesity24
  • The aims are to reduce the risk of morbidity and mortality due to noncommunicable diseases, lessen the negative psychosocial effects of obesity both in childhood and adulthood and reduce the risk of the next generation developing obesity. (who.int)
  • Among the noncommunicable disease risk factors, obesity is particularly concerning and has the potential to negate many of the health benefits that have contributed to increased life expectancy. (who.int)
  • The development of type II diabetes (T2D) is strongly associated with obesity and both are well-established risk factors for cardiovascular disease. (nih.gov)
  • Multivariate analysis statistical analyses were conducted by using Epi Info for showed that diabetes and class III obesity were associated Windows version 3.5.1 (Centers for Disease Control and with death. (cdc.gov)
  • In the final rule, we added paragraphs to the prefaces of the musculoskeletal, respiratory, and cardiovascular body system listings that provide guidance about the potential effects obesity has in causing or contributing to impairments in those body systems. (ssa.gov)
  • They also instruct adjudicators to consider the effects of obesity not only under the listings but also when assessing a claim at other steps of the sequential evaluation process, including when assessing an individual's residual functional capacity. (ssa.gov)
  • Obesity is a complex, chronic disease characterized by excessive accumulation of body fat. (ssa.gov)
  • Obesity is generally the result of a combination of factors (e.g., genetic, environmental, and behavioral). (ssa.gov)
  • Description Inflammation, a complex process, involving numerous mediators of cellular and plasma origins, is considered to be a critical factor in many human diseases and conditions, including obesity, cardiovascular diseases, diabetes, aging, and cancers. (rutgers.edu)
  • The most common chronic conditions among seniors include type II diabetes, heart disease, obesity and cancer. (atoncenter.com)
  • 5 The aetiological risk factors leading to the onset of CVD are well recognised and include hyperlipidaemia, hypertension, diabetes, obesity, smoking and lack of physical activity. (uk.com)
  • health outcomes including cardiovascular disease, obesity, diabetes, depression, and anxiety, as well as safety issues related to drowsy driving and injuries. (cdc.gov)
  • Cardiovascular disease has been elevated to this position by a combination of factors that include urbanization and its attendant effects, such as obesity, a sedentary lifestyle, changes in dietary habits, and smoking. (revespcardiol.org)
  • Cardiovascular (CV) risk factors such as hypercholesterolemia, hyperglycaemia, obesity, hypertension, smoking, and aging promote vascular inflammation and endothelial activation [ 7 - 9 ]. (hindawi.com)
  • Alongside other factors, the trend has led to an increase in both obesity and chronic diseases. (spiritualityhealth.com)
  • It was evidenced the importance of research in the investigation of better ways to obtain the public health of a given community, bringing discussion of themes that involve aspects of human growth and development such as nutritional aspects, sexuality, motor development, covering situations and diseases as obesity, cerebral palsy, dyslexia and violence. (bvsalud.org)
  • Obesity is the most prevalent nutritional disease in public health in children and adolescents in the United States, with approximately 21-24% of children being overweight and another 16-18% being obese, and the prevalence is higher among specific ethnic groups. (bvsalud.org)
  • These studies are of great importance at the national level, since obesity in Brazil is already of great importance in the Public Health of Children and Adolescents and presents severe complications, that mainly include type 2 diabetes, hypertension, hyperlipidemia, bone maturation and accelerated growth, ovarian hyperandrogenism, cholecystitis, pancreatitis and pseudo-brain tumor. (bvsalud.org)
  • Obesity: Being significantly overweight can raise the risk of developing diabetes and high blood pressure, two major risk factors for developing kidney disease. (keystone.health)
  • As we grow older, our bodies undergo an ageing process, which affects many risk factors for heart attack, such as hypertension, high cholesterol, obesity and diabetes. (veritascare.co.uk)
  • Consuming foods and beverages high in added sugars during childhood is linked to the development of risk factors for heart disease , including an increased risk of obesity and elevated blood pressure. (harvard.edu)
  • The recommendations are based on a review of available evidence examining the cardiovascular health impacts of added sugars on children, including effects on blood pressure, lipids, insulin resistance and diabetes, nonalcoholic fatty liver disease, and obesity. (harvard.edu)
  • Particularly of interest is in cardiovascular diseases and their risk factors, such as type 2 diabetes and obesity, psychological outcomes and the aging process. (lu.se)
  • Persons in all age groups should be encouraged to engage in regular physical activity to maintain functional capacity and protect against conditions such as obesity and against disease processes such as coronary heart disease and adult-onset diabetes. (cdc.gov)
Hypertension7
Coronary26
Incidence11
  • Although significant reductions have occurred in the incidence of cardiovascular disease (CVD) since the mid-1970s, this is still the primary cause of morbidity and mortality in many countries [1,2]. (who.int)
  • Racist and discriminatory federal, state, and local housing policies significantly contribute to disparities in cardiovascular disease incidence and mortality for individuals that self-identify as Black or African American. (frontiersin.org)
  • 1-5 At the same time, the Japanese enjoy far lower incidence of most chronic, age-related diseases than Western populations. (lifeextension.com)
  • Studies have reported that there has been an increase of 2 - 5% suicide or homicide were associated with non-HDL cholesterol in the annual incidence of type 1 diabetes (T1D) worldwide. (who.int)
  • The worldwide incidence of type 2 diabetes (T2D) in children and for cardiovascular disease in adults. (who.int)
  • The shear incidence of both diseases in any given population means there will be overlap - this likely explains why many people with psoriasis also develop CVD at some point in their lives. (cardiometabolichealth.org)
  • Atherosclerosis and hair greying occur through similar biological pathways and the incidence of both increases with age," said Dr Samuel. (sunstar.com.ph)
  • Gestational diabetes mellitus (GDM) is a common complication of pregnancy, with a rising incidence, affecting around 1 in 6 births globally, with prevalence varying across different regions and populations [ 1 ]. (biomedcentral.com)
  • The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. (oatext.com)
  • Participants were then followed for 24years after completion of the trial, during which we compared the incidence and hazard ratios for CVD and microvascular disease in each group and estimated the differences in their median time to onset from parametric Weibull distribution models. (cdc.gov)
  • After completion of the trial, among those with diabetes, IGT and NGT, the 24year cumulative incidence of CVD was 64.5%, 48.5% and 45.1%, respectively, and 36.8%, 21.7% and 16.5% for microvascular diseases. (cdc.gov)
Stroke12
  • ROS species are considered as important causative factors in the development of certain diseases such as diabetes, stroke, arteriosclerosis, cancer and cardiovascular diseases, in addition to the aging process. (intechopen.com)
  • P = .031), smaller chamber volumes, and lower stroke volume, but higher contractility.ConclusionsThe results of this study support a causal role of low birth weight in cardiovascular disease, even after accounting for the influence of the intrauterine environment. (imperial.ac.uk)
  • Clinical outcomes included 30-day major adverse cardiovascular events (MACE: which included death, MI, and stroke), in-hospital complications, and long-term all-cause mortality. (springer.com)
  • Myocardial infarction, end-stage renal disease and stroke may be induced due to complications of DM [1]. (escardio.org)
  • Non-Hispanic black adults are at least 50% more likely to die of heart disease or stroke prematurely (i.e., before age 75 years) than their non-Hispanic white counterparts ( 5 ). (cdc.gov)
  • Increased danger of cardiovascular illness, heart attack, and stroke are associated with untreated high cholesterol. (tutorialspoint.com)
  • A stroke, sometimes referred to as a cerebrovascular accident or cerebrovascular disease, can occur when there is an issue with the vessels circulating blood in the brain. (columbia.edu)
  • Part of stroke awareness is also knowing about risk factors and prevention methods. (columbia.edu)
  • It's wise for those with cardiovascular or stroke risk factors to speak with their health care provider about preventative options, as there are many effective interventions that can mitigate risk. (columbia.edu)
  • For example, studies have found that quitting smoking decreases the risk of ischemic stroke over time, with excess tobacco-related risk in middle-aged women disappearing two to four years after quitting. (columbia.edu)
  • Cardiovascular Disease: A history of heart disease or stroke can increase the risk of kidney disease. (keystone.health)
  • Early diagnosis and treatment of heart disease can help prevent serious complications such as heart attack or stroke. (veritascare.co.uk)
Chronic respiratory diseases2
  • This review describes, analyzes and compares the effects of different types of diets in reducing the onset of typical Western countries non-communicable diseases (NCDs) (cardiovascular diseases, tumors, chronic respiratory diseases, diabetes, etc.), thus increasing the average lifespan. (iospress.com)
  • By 2020, cardiovascular diseases, cancers, chronic respiratory diseases and diabetes will be among the main causes of morbidity and mortality in Africa. (who.int)
Respiratory3
  • Common co-morbidities are: diabetes, venous insufficiency or peripheral arterial disease, respiratory and cardiovascular disorders, malignancies and autoimmune disorders. (wikipedia.org)
  • Cardiovascular diseases (CVDs) account for most NCDs deaths (17.7 million people annually), followed by cancers (8.8 million), respiratory diseases (3.9 million) and diabetes (1.6 million) [ 1 ]. (iospress.com)
  • With cardiovascular diseases, diabetes, chronic respiratory disorders and cancer rising across the board in all industrialized countries, now is the time to hone in on preventive strategies. (naturalnews.com)
Mellitus9
Managing cardiovascular risk1
  • Is cholesterol the forgotten biomarker in managing cardiovascular risk in children with type 1 diabetes? (uk.com)
Cancers1
Atherosclerosis6
  • Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress and endothelial dysfunction. (hindawi.com)
  • Oxidation of low-density lipoprotein (LDL) cholesterol is one of the key factors for the development of atherosclerosis. (hindawi.com)
  • Inflammation and immunity are key factors for the development and complications of atherosclerosis, and therefore, the whole atherosclerotic process is a target for diagnosis and treatment. (hindawi.com)
  • Therefore, with the aim to summarize the current knowledge on the initiation of the atherosclerotic process, in this paper, we review the early markers of atherosclerosis and we address the main therapeutic targets for preventing atheroma formation at its very initial stages focusing on inflammation, oxidative stress, endothelial dysfunction, and the interaction between platelets and endothelium. (hindawi.com)
  • Some heart diseases, such as atherosclerosis, develop over a long time without causing visible symptoms. (veritascare.co.uk)
  • Claudication, which is defined as reproducible ischemic muscle pain, is one of the most common manifestations of peripheral arterial occlusive disease (PAOD) caused by atherosclerosis. (medscape.com)
Outcomes3
  • Some postulate that the chronic stress documented to occur in some communities near hazardous waste sites could possibly lead to an array of biopsychosocial effects, including physical health effects from chronic stress (possible health outcomes affected by stress include cardiovascular, gastrointestinal disorders, and skin), increases in the prevalence of certain psychological disorders, and social disruption. (cdc.gov)
  • The use of PD-L1 as a biomarker for the detection and monitoring of BCa has the potential to significantly improve patient outcomes by allowing for earlier detection and more effective management of the disease. (bvsalud.org)
  • Further research into the utility of eHealth in cardiovascular follow-up after complicated pregnancies should include longer-term follow-up and core cardiovascular outcomes. (biomedcentral.com)
Epidemiology1
  • We were, in fact, both surprised and disappointed that there were no improvements in cardiovascular and retinopathy disease rates, particularly because other complications improved so dramatically, said Trevor Orchard, M.D., professor of epidemiology, medicine and pediatrics at GSPH and principal investigator of the EDC. (webwire.com)
Adults13
  • The aim of this study was to determine the predictors of diet and lifestyle-related CVD risk factors (total cholesterol, LDL, HDL, triglycerides, blood glucose and systolic and diastolic blood pressure) in adults residing in an urban district of Tehran. (who.int)
  • b) latent autoimmune diabetes of adults (LADA), usually occurring in men over 40 years of age, in whom a progressive autoimmune process destroys the beta cells of pancreas, which is similar to type 1 DM. (escardio.org)
  • The National Institute of Clinical Excellence (NICE) guidelines 1 recommend considering statin treatment for the primary prevention of cardiovascular disease in all adults with type 1 diabetes, and offering statin treatment to adults with type 1 diabetes who are older than 40 years of age or who have had diabetes for more than 10 years. (uk.com)
  • Dyslipidaemia is often overlooked and inadequately treated in young people with diabetes, even though CVD remains a significant cause of mortality in adults with diabetes. (uk.com)
  • To provide updated and more detailed information about which occupation groups have the highest prevalences of short sleep duration, CDC analyzed data from currently employed adults surveyed for the 2013 and 2014 Behavioral Risk Factor Surveillance System (BRFSS) in 29 states. (cdc.gov)
  • Ali et al, reported that although there have been improvements in risk factor control and adherence to preventative practices, almost half of U.S. adults with diabetes did not meet the recommended goals for diabetes care from 1999-2010. (nih.gov)
  • Consuming higher levels of omega-3 polyunsaturated fatty acids (PUFAs) is associated with larger hippocampal volumes and better abstract reasoning in healthy middle-aged adults, new research shows. (medscape.com)
  • Although clinically relevant lesions become evident in middle-aged adults, it has been demonstrated that fat accumulation (known as fatty streaks) begins in early childhood [ 5 ]. (hindawi.com)
  • A wealth of scientifically validated research studies now highlight the importance of eliminating fructose in all its forms from the diets of both adults and children alike to dramatically reduce risk of diabetes and heart disease. (ironmagazine.com)
  • This study assesses changes in the prevalence and distribution of noncommunicable diseases (NCDs) and related risk factors among Brazilian adults from the 2013 and 2019 Brazilian National Health Surveys (PNS). (scielosp.org)
  • There leading cause of death in adults, accounting were 8071 individuals aged 30 years who for approximately one-third of all deaths in completed the baseline survey and whose people over the age of 35 years [ 3 ]. (who.int)
  • AIMS/HYPOTHESIS: We aimed to determine associations of regression to normal glucose tolerance (NGT), maintaining impaired glucose tolerance (IGT) or progression to diabetes with subsequent risks of CVD and microvascular disease among Chinese adults with IGT. (cdc.gov)
  • In the MOS cohort (Paper II), we found that adults born with low birth weight (LBW) but who attained a higher body mass index (BMI) at age 20 (mismatch) had significantly higher systolic and diastolic blood pressure (BP) compared to those born with LBW but continued to have low BMI at age 20. (lu.se)
Primary Prevention of Cardiovascular Disease1
Prevention and control of noncommunicable diseases1
  • The Sustainable Development Goals, set by the United Nations in 2015, identify prevention and control of noncommunicable diseases as core priorities. (who.int)
Inflammation5
  • Here, we review these societal and structural factors and then link them with biological processes such as telomere shortening, allostatic load, oxidative stress, and tissue inflammation. (frontiersin.org)
  • We propose that racial residential segregation and discrimination increases tissue inflammation and cytokine production, resulting in dysregulated immune signaling, which promotes plaque formation and cardiovascular disease. (frontiersin.org)
  • Changes in sleep and alterations in circadian timing over the lifespan impact a wide variety of physiological systems, including those that play an important role modulating weight, metabolism, inflammation, and cardiovascular functioning. (concordia.ca)
  • Different aspects of this relationship, such as genetic, environmental, and social risk factors, as well as pathogenic and pharmacological connections have been explored.One particularly compelling hypothesis is that systemic inflammation present in both psoriasis and CVD either leads to, or exacerbates, each disease. (cardiometabolichealth.org)
  • Besides the importance of this process, oxidation of LDL is not the sole initiator of inflammation, as the imbalance between oxidants and antioxidants is also important for the process of atherogenesis. (hindawi.com)
Disorders6
  • These disorders are called comorbidities and may interfere with circulatory and metabolic body functions, levels of various physiological assessment components (sugar, albumin, etc.), and induce other factors that negatively affect the healing. (wikipedia.org)
  • Free radicals have been associated with pathogenesis of various disorders like cancer, diabetes, cardiovascular diseases, autoimmune diseases, neurodegenerative disorders and are implicated in aging. (nutrimedical.com)
  • Among the factors leading to pathological processes, microbes, viruses, gene dysregulation and immune system disorders have been described. (mdpi.com)
  • The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. (nih.gov)
  • Circadian rhythms are important during each lifestage for the regulation of processes that may influence the development of these disorders. (concordia.ca)
  • Consumption of fructose is higher in children and adolescents, placing them at increased risk for heart disease and metabolic disorders such as diabetes. (ironmagazine.com)
Cause of mortality1
  • Cardiovascular diseases (CVD) are the leading cause of mortality in the Western population [ 1 ]. (hindawi.com)
Cohorts2
  • On the other hand, there were no differences across cohorts for rates of cardiovascular disease events and cardiac intervention procedures. (webwire.com)
  • The overall aim of the thesis was to elucidate the influence of early life factors, such as birth weight and gestational age, on adult organ traits and disease risk, based on a systematic review and meta-analysis, and data from three population-based cohorts, including Malmö Offspring Study (MOS) cohort, LifeGene Study cohort, and Malmö Birth Data cohort. (lu.se)
Metabolism3
  • But with age and some chronic medical conditions, the attacking microRNA numbers dwindle, reducing our ability to respond to viruses, says Dr. Carlos M. Isales, co-director of the MCG Center for Healthy Aging and chief of the MCG Division of Endocrinology, Diabetes, and Metabolism. (scitechdaily.com)
  • Finally, it will describe the impact of different dietary restrictions in modulating the genetic pathways that regulate metabolism and aging. (iospress.com)
  • One of the study authors, Dr. Norman Pollock noted "Fructose itself is metabolized differently than other sugars and has some byproducts that are believed to be bad for us… there's something in the syrup processing that plays a role in the bad byproducts of metabolism. (ironmagazine.com)
Genetic7
  • Genetic, environmental, behavioral and dietary factors influence the pathways that regulate aging and life expectancy, thus rendering longevity a very complex phenomenon. (iospress.com)
  • At present, it is not clear what lifestyle or genetic factors influence a person's biological age. (scienceblog.com)
  • Other factors can be diseases, genetic predisposition and psychological and social factors. (umhospital.org)
  • However, the influences on intake, the influences on expenditure, the metabolic processes in between, and the overall genetic controls are complex and not well understood. (ssa.gov)
  • This variation is thought to be related to various degrees of genetic and environmental factors. (cardiometabolichealth.org)
  • Further research is needed, in coordination with dermatologists, to learn more about the causative genetic and possible avoidable environmental factors that determine hair whitening," she added. (sunstar.com.ph)
  • Polycystic Kidney Disease: A genetic disorder characterized by the growth of numerous cysts in the kidneys, potentially impairing kidney function. (keystone.health)
Metabolic3
  • The achievement, at a global level, of a "healthy aging phenotype" defined as "the condition of being alive, while having highly preserved functioning metabolic, hormonal and neuroendocrine control systems at the organ, tissue and molecular levels" [ 10 ], is the most ambitious objective that modern science should achieve. (iospress.com)
  • Metabolic syndrome (MetS) is characterized by a constellation of interacting risk factors including impaired glucose tolerance (IGT), atherogenic dyslipidemia, elevated blood pressure, and visceral adiposity. (nature.com)
  • Creatinine is produced by creatine and creatine phosphate as a result of muscle metabolic processes. (cdc.gov)
Adverse cardiovascular events1
  • Methotrexate, for instance, is one of the oldest systemic treatment agents and was thought to have new promises in reducing vascular diseases in patients with psoriasis, but the CIRT trial showed that low-dose methotrexate did not reduce adverse cardiovascular events in patients with established CVD. (cardiometabolichealth.org)
Development of cardiovascular1
  • Knowing that vascular dysfunction is an early event in the development of cardiovascular disease in obese diabetic (OB-T2D) patients, The investigators set their long-term goal to define molecular mechanisms of vascular dysfunction and corrective strategies that target these mechanisms such as physical activity and weight loss. (nih.gov)
Prevalent3
  • Diabetes is equally prevalent in both men and women, with those aged from 75 to 79 years of age having the highest rates of the disease [3]. (escardio.org)
  • In addition to other possible confounders, researchers adjusted for vascular risk factors, such as systolic blood pressure, antihypertensive medication, smoking, diabetes, total cholesterol to high density lipoprotein ratio, body mass index, lipid-lowering medication use, and prevalent cardiovascular disease. (medscape.com)
  • To provide insight into the possible reasons for the presumed immune sufficiency to coronavirus disease 2019 (COVID-19) in Africa, this review critically examines literature published from 2020 onwards on the dynamics of COVID-19 infection and immunity and how other prevalent infectious diseases in Africa might have influenced the outcome of COVID-19. (bvsalud.org)
Morbidity and morta1
  • Among the individuals aged 60 and over, NCDs account for more than 87% of the disease burden, with an higher age-related occurrence of chronic diseases, disabilities, morbidity and mortality [ 4-7 ]. (iospress.com)
Type16
  • In men, a more than 94 centimetres waist circumference carries an increased possibility of cardiovascular diseases and type 2 diabetes. (umhospital.org)
  • While type 2 DM did not influence the in-hospital mortality hazard, we showed that the presence of DM among patients with ACS referred to CABG, is a powerful risk factor for long-term mortality, especially when insulin was included in the diabetic treatment strategy. (springer.com)
  • DM develops due to either a lack of insulin production (type 1 DM), as a result of destroyed beta cells of pancreas due to an autoimmune reaction, or resistance to insulin (type 2 DM), where insulin is being produced at least in the early stages of disease because beta cells are still present, but tissues do not respond to insulin [1]. (escardio.org)
  • Another type of diabetes that is similar to type 2 DM, but developing at a younger age, is called maturity onset DM (MODY) [1]. (escardio.org)
  • Wendy Frost, Advanced Dietitian in Paediatrics, reports on an audit amongst children with type 1 diabetes carried out with the aim of identifying those who are potentially more at risk of cardiovascular disease. (uk.com)
  • Children and young people with type 1 diabetes (T1D) are faced with an increased risk of developing cardiovascular disease (CVD). (uk.com)
  • The NICE guidelines for Management of Children and Young People with Diabetes 2015 do not include cholesterol screening for children with type 1 diabetes. (uk.com)
  • 4 assessed the cholesterol screening of children with type 1 diabetes by sending an online survey to 280 children's diabetes professionals. (uk.com)
  • The EDC is an ongoing investigation to document long-term complications of type 1 diabetes among juveniles and adolescents who were patients at Children s Hospital of Pittsburgh between 1950 and 1980. (webwire.com)
  • Doctors have long considered type 1 diabetes a small blood vessel problem, so they have traditionally not focused on the potential large blood vessel complications, such as cardiovascular disease. (webwire.com)
  • Indeed, although focusing primarily on blood-glucose control has significantly decreased early death in type 1 diabetics, the data from this study suggests these individuals remain significantly burdened with other serious chronic diseases. (webwire.com)
  • Ms. Pambianco added that many of the guidelines currently used for managing type 1 diabetes are derived from what we know about people with type 2 diabetes. (webwire.com)
  • Individuals with type 2 diabetes have decreased thermoregulatory responses compared with healthy counterparts, characterized by decreased SkBF and sweating. (intechopen.com)
  • However, appropriate nutritional intervention, implementation, and ultimate compliance with the plan remain some of the most vexing problems in diabetes management for three major reasons: First, there are some differences in the dietary structure to consider, depending on the type of diabetes and medication the PWD is taking. (nih.gov)
  • Women who have had GDM in their pregnancy have an increased risk of type 2 diabetes and cardiovascular disease later in life compared to those with normoglycemic pregnancies [ 3 ]. (biomedcentral.com)
  • Trending Clinical Topic: Intermittent Fasting New findings about intermittent fasting as an intervention for nonalcoholic fatty liver disease, type 2 diabetes, and gastroesophageal reflux disease led to this week's top trending clinical topic. (medscape.com)
Increases2
Peripheral4
  • Its use is supported by a series of randomized and controlled trials assessing diseases that affect the peripheral nerve, neuromuscular junction, and skeletal muscle. (nursingcenter.com)
  • Peripheral artery disease - a condition in which blood vessels in the legs, arms or other parts of the body become narrowed or blocked. (veritascare.co.uk)
  • This is the most common area for peripheral vascular disease. (medscape.com)
  • The US FDA has approved the first drug-coated balloon (DCB) for the treatment of peripheral arterial vascular disease, the Lutonix 035 Drug Coated Balloon Percutaneous Transluminal Angioplasty Catheter (Lutonix DCB). (medscape.com)
Overall cardiovascular1
  • No studies were identified that examined follow-up regarding long-term overall cardiovascular risk after gestational diabetes. (biomedcentral.com)
Glucose8
  • It has been shown that elevated serum levels of low-density lipoprotein (LDL) cholesterol, total cholesterol and triglycerides, low levels of high-density lipoprotein (HDL) cholesterol and abnormal blood glucose levels are the dominant risk factors for CVD [4,5]. (who.int)
  • Our data show that focusing solely on blood-glucose control is only postponing, not preventing, some of the more significant complications of this disease. (webwire.com)
  • Conducted on 945 people between 55 and 80 years of age in Spain's autonomous Valencian Community, the study showed that when fish was included in the diet, participants had lower glucose concentrations in their body and a smaller risk of developing diabetes. (spiritualityhealth.com)
  • The study detailed an analysis of 559 adolescents, aged 14 to 18 and detailed cardiovascular risk factors including high blood pressure, fasting glucose, insulin resistance and blood inflammatory factors. (ironmagazine.com)
  • Many processed food and drink manufacturers use liberal quantities of pure high fructose corn syrup extract that is metabolized through a different pathway as compared to glucose or table sugar. (ironmagazine.com)
  • Basic research should examine the effects of exercise on degenerative processes, such as cardiovascular disease, glucose and lipid impairment, osteoporosis and osteoarthritis, psychosocial dysfunction, and immune dysfunction. (cdc.gov)
  • Variables independently associated with CHD were female sex, age, systolic blood pressure, 2-hour postprandial glucose, body mass index, waist-to-hip ratio and LDL/HDL cholesterol ratio. (who.int)
  • It pulse rate, ECG and anthropometrical seems likely that changing lifestyles such as measures and laboratory measurements for high consumption of processed foods rich lipid and glucose profiles. (who.int)
Middle-aged2
  • Presbyopia is the main reason so many middle-aged folks start wearing reading glasses. (warbyparker.com)
  • With the current generation of antiretroviral therapies (ARTs) offering patients a life expectancy roughly in line with that of the general population, HIV is well on its way to becoming an epidemic of the middle-aged and elderly. (natap.org)
Patients24
  • The most important and striking feature of COVID-19 is the increased case fatality rate in aged individuals," the investigators write, with the CDC reporting that nearly half of the patients requiring hospitalization are age 65 and older, and these more senior individuals account for about 80% of the deaths. (scitechdaily.com)
  • 2009, we obtained data for 157 hospitalized patients with confi rmed cases of this disease. (cdc.gov)
  • total of 44,544 pandemic infl uenza cases were confi rmed Diabetes was the most frequent underlying medical and 2,051 deaths were reported in Brazil, corresponding condition (21%) in obese case-patients. (cdc.gov)
  • Thirty-four to notifi cation and death rates of 23.3 cases and 1.1 deaths (49%) of 70 case-patients who did not have risk factors per 100,000 population. (cdc.gov)
  • To identify risk factors for Taking medication was reported by 107 (68%) death caused by pandemic (H1N1) 2009, we analyzed data case-patients, but none received oseltamivir before for patients hospitalized with confi rmed pandemic (H1N1) hospitalization. (cdc.gov)
  • Diabetic patients are at an increased risk of cardiovascular events and cardiovascular mortality. (escardio.org)
  • Despite the young age of these patients, serious cardiovascular events do occur. (escardio.org)
  • The study group consisted of all the over-12-year-old patients in the local hospital children and young people's diabetes clinic. (uk.com)
  • To determine the prevalence of dyslipidaemia and HT in paediatric diabetic patients seen at Tygerberg Hospital (TBH) and establish whether either is associated with body mass index (BMI), glycosylated haemoglobin (HbA1c) or duration of diabetes. (who.int)
  • A retrospective study of 154 diabetic patients, aged 1 - 19 years, seen at TBH between 2007 and 2017, was undertaken. (who.int)
  • Dyslipidaemia was diagnosed in 62.6% (n=82/131) of adolescents with poorly controlled diabetes (p=0.04) and in 71.7% (95% CI 59.0 - 81.7) of patients 16 years of age (p=0.005). (who.int)
  • Because most acute cardiovascular events are associated with thrombosis, intensive antiplatelet therapy offers a major clinical benefit to diabetic patients. (aging-us.com)
  • However, our study suggests that doctors and their patients need to pay more attention to factors that affect the larger blood vessels, such as lipids and blood pressure, explained Georgia Pambianco, M.S., M.P.H., lead study author, who has been a member of the EDC research staff from its inception. (webwire.com)
  • Increased microalbuminuria is a sign of renal disease and may be predictive of nephropathy risk in patients with insulin-dependent diabetes. (cdc.gov)
  • and the majority of deaths in patients with psoriasis being attributed to cardiovascular or cerebrovascular events. (cardiometabolichealth.org)
  • The established pharmacotherapy used to treat psoriasis has a dual effect on patients' cardiovascular risk profile. (cardiometabolichealth.org)
  • A 2015 modelling study concluded that by 2030, three-quarters of Dutch patients infected with HIV will be aged 50 years and over. (natap.org)
  • this is especially noticeable in those who started treatment late in the disease course, which really means the vast majority of patients around the world", explains Peter Hunt (University of California, San Francisco, CA, USA). (natap.org)
  • The investigators in the Dutch study predict that by 2030, 84% of people with HIV will have at least one non-communicable disease, 29% will have at least three co-morbidities, and more than half will be prescribed medications alongside their ART, with a fifth of patients expected to receive at least three other medications. (natap.org)
  • There is also substantial evidence that statins (prescription medications that lower cholesterol in the blood) and lowered blood pressure under the care of a health care provider can substantially reduce the risk of cardiovascular events in patients with diabetes. (columbia.edu)
  • A larger study including men and women is required to confirm the association between hair greying and cardiovascular disease in patients without other known cardiovascular risk factors. (sunstar.com.ph)
  • However, lowering LDL levels is a common clinical practice to reduce oxidation and the risk of major events in patients with cardiovascular diseases (CVD). (hindawi.com)
  • These conditions occur for patients with severe disease but also for patients who had mild or even asymptomatic acute infection. (cdc.gov)
  • The patients can be medically complex, and a variety of processes may be occurring. (cdc.gov)
20191
  • Este trabajo evalúa los cambios en la prevalencia y distribución de las enfermedades no transmisibles (ENT) y factores de riesgo relacionados entre adultos brasileños en las Encuestas Nacionales de Salud (PNS) de 2013 y 2019 , basadas en la hipótesis de que las condiciones económicas en deterioro durante este período conducirían a ENTs entre los grupos de población menos favorecidos. (scielosp.org)
Life expectancy4
  • Brian Martin and his colleagues from the Institute of Social and Preventive Medicine (ISPM) at the University of Zurich looked into the combined and individual effects of four factors on life expectancy. (naturalnews.com)
  • The effect of each individual factor on life expectancy is relatively high," stated Eva Martin-Diener. (naturalnews.com)
  • Eating red meat, on the other hand, was linked to higher cardiovascular risk, higher blood pressure, diabetes, and a moderate decrease in life expectancy, mainly due to cancer or heart disease. (spiritualityhealth.com)
  • 1. Ageing is a normal process and longer life expectancy is a positive outcome of a country's socioeconomic development. (who.int)
Individuals aged 301
  • BACKGROUND: Non-communicable diseases (NCDs) pose a substantial global health challenge, resulting in an annual death toll of over 15 million individuals aged 30 to 69. (bvsalud.org)
Lipoprotein1
  • 12] Screening should commence at 2 years trial, small very low-density lipoprotein (VLDL), small high- of age if there is a family history of hypercholesterolaemia, early density lipoprotein (HDL), medium low-density lipoprotein (LDL) cardiovascular disease or if the family history is unknown. (who.int)
Affects4
  • Yes-research suggests that presbyopia affects almost everyone as they age and is "nearly universal" in people over 65 . (warbyparker.com)
  • For people with diabetes, drinking affects blood sugar levels. (atoncenter.com)
  • Psoriasis is the number one cutaneous disease, affecting an estimated 8 million people in the U.S. This chronic inflammatory multisystemic skin condition primarily affects skin and joints, and is characterized by scaly skin lesions in the form of patches, plaques or pustules with episodes of relapse and remission. (cardiometabolichealth.org)
  • Evidence for a shared pathophysiology in psoriasis and CVD raises the question of whether the cutaneous disease or its treatment is the factor that affects cardiovascular risk. (cardiometabolichealth.org)
Gestational diabetes2
  • Our aim was to systematically review the existing literature on cardiovascular follow-up after gestational diabetes, the utility of eHealth technology for this purpose, and to identify research gaps. (biomedcentral.com)
  • This scoping review of the existing literature revealed neither an established systematic cardiovascular follow-up strategy for women after gestational diabetes nor evidence that eHealth technologies are superior to conventional follow-up. (biomedcentral.com)
Nephropathy1
  • This includes those who have established nephropathy, or other cardiovascular risk factors. (uk.com)
Acute4
  • ACSIS is managed by the Working Group on Acute Cardiovascular Care of the Israel Heart Society, in participation with the Israeli Center for Cardiovascular Research. (springer.com)
  • Controlling these factors reduces the risk of acute vascular complications and death from CVD [ 1 , 7 ]. (hindawi.com)
  • Kidney disease can be either chronic or acute. (keystone.health)
  • Acute kidney disease is often temporary and can be caused by a sudden injury or trauma, while chronic kidney disease (CKD) develops over time and is usually permanent. (keystone.health)
Diabetic2
  • Poor glycaemic control, dyslipidaemia and HT are common in diabetic children, putting them at risk of cardiovascular complications in adulthood. (who.int)
  • Normal ApoE −/− and diabetic mice were allocated to four groups (n = 15): normal diet, normal diet plus rutin, diabetic, and diabetes plus rutin. (aging-us.com)
Onset4
  • These studies showed that Black/African Americans had earlier onset of disease, a more aggressive disease course, and worse survival compared to non-Latino Whites ( 6 ). (frontiersin.org)
  • This childhood-onset group is at a higher risk for cardiovascular disease even at early middle age. (webwire.com)
  • Compared with those who developed diabetes during the trial, the median time to onset of diabetes was delayed by 14.86years (95% CI 12.49, 17.25) in the NGT and 9.87years (95% CI 8.12, 11.68) in the IGT groups. (cdc.gov)
  • This may ultimately predispose the individual to the later onset of some diseases in adulthood, a process known as Developmental Origins of Health and Disease (DOHaD). (lu.se)
Noncommunicable1
  • In accordance with the latest report of the World Health Organization (WHO), deaths from noncommunicable diseases account for almost 74% and they are mainly attributed to CVD [ 10 ]. (hindawi.com)
Paediatric diabetes3
  • The National Paediatric Diabetes Audit (NPDA, 2020-2021), however, lists annual cholesterol measurement in children over 12 as one of the seven core care processes. (uk.com)
  • Data was collected from hospital records and analysed for HbA1c, BMI percentile and lipids for children over 12 years of age in our paediatric diabetes clinic. (uk.com)
  • In the Paediatric Diabetes Unit at Tygerberg Hospital (TBH) correlated, while HDL particle size was negatively correlated, the practice has been to monitor fasting lipid profiles annual y in to HbA1c levels. (who.int)
Degenerative1
  • Research should determine the role of physical exercise in maintaining functional capacity and preventing degenerative disease, especially in perimenopausal and postmenopausal women, by increasing or maintaining muscular strength and endurance, cardiorespiratory function, agility, coordination, and flexibility. (cdc.gov)
Physiological2
  • Thermoregulatory function is associated with individual somatotype, fitness level, normal aging, and physiological status and diseases. (intechopen.com)
  • Circadian misalignment is the consequence of desynchronization, or alterations in the timing and rhythm of the physiological cycles, that in turn, superimpose incompatible biochemical processes. (concordia.ca)
Premature2
  • In this address, the AHA declared structural racism a key cause of premature death from cardiovascular disease ( 3 ) and called for change through strategic goals and increased focus on health equity ( 3 ). (frontiersin.org)
  • Chronic kidney disease (CKD) is a serious condition associated with premature mortality, decreased quality of life, and increased health-care expenditures. (cdc.gov)
Inflammatory4
  • Taken together, the results suggest that inotilone has potential to be developed into an effective chemopreventive agent for the treatment of a variety of inflammatory diseases, especially the prevention and treatment of epithelial skin cancer. (rutgers.edu)
  • The evidence supporting this theory shows other disease states and risk factors, and an array of complex immune and non-immune inflammatory mediators present a plausible link. (cardiometabolichealth.org)
  • Pharmacotherapy also presents a potential association, especially with the advent of biological agents which directly act on inflammatory factors shared by the two diseases. (cardiometabolichealth.org)
  • The atherosclerotic process is accelerated by a myriad of factors, such as the release of inflammatory chemokines and cytokines, the generation of reactive oxygen species (ROS), growth factors, and the proliferation of vascular smooth muscle cells. (hindawi.com)
Infectious diseases3
  • The group has previously worked on a variety of tropical and emerging infectious diseases including Dengue, Zika, and SARS-CoV-2. (a-star.edu.sg)
  • Laboratory and animal studies further reveal that fucoidans prevent certain infectious diseases, and block cancer cells from spreading and trigger their early death. (lifeextension.com)
  • The high burden of infectious diseases and the extensive vaccination campaigns previously conducted in Africa could have induced specific and non-specific protective immunity to infectious pathogens in Africans. (bvsalud.org)
Intervention3
  • Determining the risk factors could provide data that would be useful in the development of an intervention programme to reduce CVD. (who.int)
  • This randomized-controlled pilot study will examine the implementation of a cardiovascular health intervention on postpartum mothers and infants. (nih.gov)
  • For each topic, we discuss the potential of stress as a risk factor and possible intervention strategies that could reduce the effects of stress. (cdc.gov)
Years24
  • A multistage stratified cluster random sampling technique was used to select 15 000 people aged 3 to 69 years from district 13 in the east of Tehran for the study. (who.int)
  • According to the report "An Aging World: 2015" the 8.5% of the world's population is more than 65 years old and, if this growing trend continues, by 2050 almost the 17% of the global population will be aged over 60 [ 2 ]. (iospress.com)
  • Between ages 40 and 75 years as part of a routine cardiovascular health check, or if you are already thought to be at risk of cardiovascular disease for another reason, or if you are starting on or taking lipid-modifying treatments (e.g. statins). (labtestsonline.org.uk)
  • Young children Those less than 5 years of age. (who.int)
  • 1 Convention on the rights of the child, Treaty Series, 1577:3(1989): PART I, Article 1 defines a child as every human being below the age of eighteen years unless, under the law applicable to the child, majority is attained earlier. (who.int)
  • The World Health Organization (WHO) defines adolescents as those between 10 and 19 years of age. (who.int)
  • The majority of adolescents are, therefore, included in the age-based definition of "child", adopted by the Convention on the Rights of the Child, as a person under the age of 18 years. (who.int)
  • To determine the mechanism of monocyte priming in humans, the study team will conduct a complete feeding trial in normal weight and metabolically healthy human subjects (20-45 years of age) using a western diet (WD), characterized as being high-saturated fat, high-fructose, and high-calorie for 8 weeks. (nih.gov)
  • 18 years of age) and information from Betine P. M. Iser, Priscilleyne O. Reis, medical chart review. (cdc.gov)
  • In 2021, the global prevalence of DM in people from 20 to 79 years of age was estimated to be 10.5% (536.6 million), and in 2045, it is expected to rise to 12.2% (783.2 million). (escardio.org)
  • The latest recommendations suggest that screening for dyslipidaemia is recommended soon after diagnosis (when glycaemia is stabilised) in all young people with T1D from age 11 years. (uk.com)
  • In this diabetes for 2 - 5 years. (who.int)
  • Examined participants aged 6 years and older. (cdc.gov)
  • The age range studied (16-90 year olds) was inclusive, and the years studied were from 1977 to 1993. (naturalnews.com)
  • On the other hand, for those between 65 and 75 years of age, these same daily choices had a much more detrimental effect on mortality risk. (naturalnews.com)
  • About 2% of the world population has some form of psoriatic disease, most presenting before 30 years old. (cardiometabolichealth.org)
  • 58% of those aged 55 years and older lived on or below the poverty line, double the rate for the general population. (natap.org)
  • UNAIDS estimates that 7·5 million people over the age of 50 years are now living with HIV. (natap.org)
  • The ages of participants ranged from 24 to 83 years (mean age, 46 years), and 53% were women. (medscape.com)
  • Researchers in Spain report that the consumption of foods from the healthy Mediterranean diet - olive oil, fresh vegetables, and fish, for example - has declined in recent years as consumers reach for more red meat and heavily processed baked goods. (spiritualityhealth.com)
  • The mean [SD] age at baseline for all participants was 52.5 [11.8] years. (naturalmedicinejournal.com)
  • In Africa, it is estimated that the number of people aged 60 years or over (called older people or the elderly) will increase from 46 million in 2015 to 147 million by 2050. (who.int)
  • In Africa, it is estimated that the number of people aged 60 years or over (called older people or the elderly) will increase from 46 million in 2015 to 147 million by 2050.1 Member States are yet to prioritize healthy ageing in their national health and development agenda and address it through a comprehensive multisectoral approach because programming for healthy ageing still remains a major challenge for the Region. (who.int)
  • Standard supine ECG data were collected for 5984 men and women aged 30 years and coded by Minnesota criteria. (who.int)
Mortality risk1
Heart disease7