• The molecular gene definition is more commonly used across biochemistry, molecular biology, and most of genetics - the gene that's described in terms of DNA sequence. (wikipedia.org)
  • Research studies on behavioral and social processes, interactions between biology, behavior and social processes, and/or methodology and measurement will be encouraged. (nih.gov)
  • As a consequence, zoology pulls on all the disciplines covered across the School of Biological Sciences, from cell and molecular biology, developmental biology, parasitology, animal behaviour, population biology and ecology - all underpinned by evolutionary thinking. (ed.ac.uk)
  • You will learn core laboratory techniques, and study modern biology subjects which span the breadth of the biological sciences subject areas. (ed.ac.uk)
  • Experimental Embryology is often referred to as a classical approach of developmental biology that has been to some extent replaced by the introduction of molecular biology and genetic techniques to the field. (mdpi.com)
  • Inspired by the combination of this approach with advanced techniques to uncover core principles of neural crest development by the laboratory of Roberto Mayor, we review key quantitative examples of experimental embryology from recent work in a broad range of developmental biology questions. (mdpi.com)
  • A new, Yale-developed synthetic biology technology allows for the tracking of previously unexplored genes and metabolic events in different organisms. (yale.edu)
  • However, Yale scientists have developed a new synthetic biology technology that acts as a sort of universal translator that can track previously unexplored genes and individual metabolic events in different organisms, they report in the April 1 online issue of the journal Cell. (yale.edu)
  • You can think of it as a universal genetic language, a sort of Rosetta Stone that can unlock the hidden genes and molecules of life," said Farren Isaacs, associate professor of molecular, cellular, and developmental biology and biomedical engineering in Yale's Faculty of Arts and Sciences and co-senior author of the paper. (yale.edu)
  • In order to study these interactions, the labs of Isaacs and co-senior author Jason Crawford, associate professor of chemistry and microbial pathogenesis and director of the Institute of Biomolecular Design and Discovery, used computational biology and DNA synthesis to create a single "synthetic genetic element," or SGE. (yale.edu)
  • Within developmental biology, we know humans grow to fit the environment that they're in, which contributes to normal human biological variation. (newindianexpress.com)
  • This course fulfills the requirement for students majoring in the biological sciences and satisfies the biology requirement for entrance into medical school. (princeton.edu)
  • Genotypes along with environmental and developmental factors determine what the phenotypes will be. (wikipedia.org)
  • Our findings demonstrate how the local environment directly affects disease risk phenotypes and that genetic variation, including less common variants, can modulate individual's response to environmental challenges. (nature.com)
  • While it is anticipated that assays should aim to characterize 100-250 genes, some phenotypes and assay formats may be more amenable to moderate scale screening against a subset (50-100) of the gene set. (nih.gov)
  • Environment chooses genes here and only certain phenotypes expressed. (the-mouse-trap.com)
  • Research at the Leibniz Institute of Plant Biochemistry (IPB) focuses on the chemical diversity, the biosynthesis, the biological roles, and the mechanisms of action of plant and fungal natural products, with an emphasis on specialized metabolites and signaling molecules. (leibniz-gemeinschaft.de)
  • Drawing from this founding population of individuals with largely French ancestry, we selected 1007 individuals to determine mechanisms by which genomes, the environment, and their interactions contribute to phenotypic variation. (nature.com)
  • The resulting phenotypic data will be integrated across modalities, levels of organization, and genes to create a harmonized, integrated knowledge base needed to substantively advance our understanding of basic gene function and, ultimately, make robust inferences into potential shared and unique disease mechanisms. (nih.gov)
  • His work has investigated the developmental pathways from abuse and neglect to psychopathology and also resilience. (psychologicalscience.org)
  • Air pollution impacts gene expression and pathways affecting cardio-metabolic and respiratory traits, when controlling for genetic ancestry. (nature.com)
  • The post holder will be required to acquire, process, and analyse metabolomic data from biological samples generated by the project team to identify relevant spectral features and metabolic pathways associated with infection, the gut microbiota, and developmental outcomes. (timeshighereducation.com)
  • Yet the hundreds of thousands of individual genetic pathways that make these structures possible and thus maintain life remain largely unexplored, in part because of the daunting complexity of variations of genetic and molecular interactions among species. (yale.edu)
  • However, less than 1% of all potential genetic pathways that affect these interactions between species have been explored. (yale.edu)
  • The study of these gene pathways has been hampered by the inability to grow microorganisms outside of their native environments and in laboratory conditions. (yale.edu)
  • Related but currently uncharacterized pathways are broadly distributed in diverse genomes, suggesting that much of the specialized nucleotide chemical and biological diversity still awaits discovery," Crawford said. (yale.edu)
  • Behavioral and social factors are important contributors to health and illness and frequently interact with biological factors to influence health outcomes. (nih.gov)
  • This research has shown that variation in a number of studied candidate genes, in interaction with child maltreatment, is associated with or predicts various psychopathological outcomes, including internalizing and externalizing problems. (psychologicalscience.org)
  • The Tumor Host Interactions program seeks to understand how the environment of tissues and cancers influences the development of cancers, the aggressiveness of these cancers, their responses to therapies, and outcomes for patients. (cancer.gov)
  • Some of the aspects contributing to denial and resistance to treatments can be automatic and unmotivated whilst others are consciously generated by patients who actively oppose to treatment, also on the basis of the biological vulnerability of altered reward and inhibition underlying these disorders [ 7 , 8 ]. (springer.com)
  • Hence new complex models that take into account the intertwined link between psychology and its biological underpinnings are necessary to better understand these disorders. (springer.com)
  • Figure 1 illustrates the EDs as developmental disorders and the vicious cycle that is elicited and maintained by the "ED identity", potentially a crucial issue in generating resistance. (springer.com)
  • Fetal alcohol spectrum disorders (FASD) due to maternal alcohol abuse results in a series of developmental abnormalities including cranial facial dysmorphology, ocular anomalies, congenital heart defects, microcephaly and intellectual disabilities. (biomedcentral.com)
  • The increased cases of neurodevelopmental disorders in children, together with their increased susceptibility to OP neurotoxicity cannot be explained by genetic factors alone but could be related to gene-environment interactions. (cdc.gov)
  • It may allow us to identify new kinds of language disorders and will clarify the relationships between language impairment and other developmental disorders. (brookes.ac.uk)
  • Studies show that developmental language disorders run in families - a brother or sister of someone who has already been diagnosed will have an increased risk of developing the disorder themselves. (brookes.ac.uk)
  • developmental language disorders are genetic and is therefore caused (at least in part) by the genes passed on from parents to children. (brookes.ac.uk)
  • The SSPsyGene Consortium aims to produce a systematic annotation of basic neurobiological function of genes associated with risk for neurodevelopmental and psychiatric disorders (NPDs). (nih.gov)
  • This effect is accompanied by epigenetic changes involving histone post-translational modifications at the mineralocorticoid receptor (MR) gene and decreased MR expression in the hippocampus. (nature.com)
  • These findings highlight the beneficial impact that early adverse experiences can have in adulthood, and the implication of epigenetic modes of gene regulation. (nature.com)
  • This is accompanied by epigenetic changes at the mineralocorticoid receptor (MR) gene and decreased MR expression, that can be mimicked in vivo by pharmacological blockade of MR. These findings highlight the potential adaptive benefit of adverse experiences in early life, and implicate a stress hormone receptor and its epigenetic regulation. (nature.com)
  • In this study, researchers found that neutral or awkward behaviour of mothers with their babies at 12 months correlated with an epigenetic change called methylation, or the addition of methane and carbon molecules, on a gene called NR3C1 when the children were 7 years old. (newindianexpress.com)
  • The range of warmth they displayed only varied slightly with the "coldest" behaviour classified as awkward or neutral, but this is exactly what the researchers hoped to test: that if even small differences in social interaction could be linked to an epigenetic change, the study said. (newindianexpress.com)
  • The enriched laboratory housing is thought to more closely resemble the natural habitat or at least provides an environment where natural behaviors can be expressed ( Wurbel, 2001 ). (frontiersin.org)
  • Prompted by earlier lines of research, studies have recently focused on several aspects including: neurobiological effects of attachment and primary relationships, complex gene-environment interaction, temperament and deficits in the development of the character, cognitive inflexibility, and those pseudo-positive meaning that patients attribute to their behaviors and symptoms. (springer.com)
  • Behaviors/social functioning: Social/situational explanations dependent on interactions with other people/cultural effects. (the-mouse-trap.com)
  • Other studies have compared obese and non-obese people for variation in genes that could influence behaviors (such as a drive to overeat, or a tendency to be sedentary) or metabolism (such as a diminished capacity to use dietary fats as fuel, or an increased tendency to store body fat). (cdc.gov)
  • The Mendelian gene is the classical gene of genetics and it refers to any heritable trait. (wikipedia.org)
  • More thorough discussions of this version of a gene can be found in the articles on Genetics and Gene-centered view of evolution. (wikipedia.org)
  • Every gene in the human body is encoded as deoxyribonucleic acid ("DNA"), and Myriad Genetics confronted the issue of whether a naturally occurring segment of DNA was eligible for patent. (nyu.edu)
  • Moreover, in Myriad Genetics , the Supreme Court found that an identical provision was inapplicable in a discussion on real and synthetic human genes, noting that the "Act does not even mention genes, much less isolated DNA. (nyu.edu)
  • Any explanation of the obesity epidemic has to consider both genetics and the environment. (cdc.gov)
  • Family health history reflects the effects of shared genetics and environment among close relatives. (cdc.gov)
  • We investigated the relationship of the microbiome with the neuroanatomy and cognitive function of 281 healthy children in a cross-sectional analysis and demonstrated that differences in gut microbial taxa and gene functions are associated with the size of brain regions and with overall cognitive function. (biorxiv.org)
  • Biological Psychiatry: Cognitive Neuroscience and Neuroimaging , 7 (11), 1103-1115. (kcl.ac.uk)
  • In the remainder of this module, we examine the answers that are emerging regarding these questions, as well as ways in which cognitive developmental research is being used to improve education. (nobaproject.com)
  • Recent advances have been made in the of host factors, polymorphisms, and candidate genes associated characterization of the immune response to low-molecular- with occupational asthma may improve our understanding of weight agents. (cdc.gov)
  • Our aim is to develop a comprehensive molecular understanding of the adaptive and developmental processes which plants evolved as a consequence of their dynamic interaction with the environment. (leibniz-gemeinschaft.de)
  • Working closely with other collaborators active in this field, we aim to identify specific genetic variants that cause this predisposition and to investigate the kinds of biological processes that they take part in. (brookes.ac.uk)
  • Our research impacts upon our understanding of the biological processes underlying speech and language development. (brookes.ac.uk)
  • The research will mainly focus on four biological processes including possible alterations of the epigenome, neuroendocrine system, inflammatome, and the gut microbiome. (plos.org)
  • Molecular and Cellular Oncology researchers work on providing insights into gene expression regulation and its deregulation in cancer, the cellular response to genomic insults, the molecular structure of cancer-relevant proteins, and new signaling transduction processes driving tumor growth. (cancer.gov)
  • The goal of the Developmental Therapeutics program is to reduce the cancer burden through the integration of the processes of discovery, development, and delivery of new anticancer agents. (cancer.gov)
  • Epigenetics are molecular processes independent of DNA that influence gene behaviour. (newindianexpress.com)
  • However, thinking also involves other mental processes that seem more basic and at which even toddlers are skilled-such as perceiving objects and events in the environment, acting skillfully on objects to obtain goals, and understanding and producing language. (nobaproject.com)
  • In contrast, Cicchetti's research has found that maltreatment often has a uniquely devastating developmental impact that ranges from the cellular to the neural to the behavioral level. (psychologicalscience.org)
  • In a further test of a novel theory that suggests autism is the consequence of abnormal cell communication, researchers at the University of California, San Diego School of Medicine report that an almost century-old drug approved for treating sleeping sickness also restores normal cellular signaling in a mouse model of autism, reversing symptoms of the neurological disorder in animals that were the human biological age equivalent of 30 years old. (technologynetworks.com)
  • anical interactions at the cellular level. (lu.se)
  • However, genes that produce repressor RNAs were proposed in the 1950s and by the 1960s, textbooks were using molecular gene definitions that included those that specified functional RNA molecules such as ribosomal RNA and tRNA (noncoding genes) as well as protein-coding genes. (wikipedia.org)
  • Therefore in this book I will consider genes as DNA sequences encoding information for functional products, be it proteins or RNA molecules. (wikipedia.org)
  • More than 60% of all drugs, including antibiotics and cancer treatments, are derived from natural products in the form of small molecules encoded by metabolic genes. (yale.edu)
  • Microorganisms that successfully join the rhizosphere community from bulk soil have access to more abundant and diverse molecules, producing a highly competitive and selective environment. (nih.gov)
  • Biological Sciences explores the study of living organisms, covering everything from the interactions of animals in their environment to how genes are expressed. (ed.ac.uk)
  • In most cases, it is likely that several genes combine to bring about a heightened risk of disorder. (brookes.ac.uk)
  • These studies have identified variants in several genes that may contribute to obesity by increasing hunger and food intake. (cdc.gov)
  • This chapter examines the consequences of genotype-by-social environment interactions (GSEIs) for the evolution of male sexual traits and, more generally, the operation of sexual selection. (bath.ac.uk)
  • In other words, according to the "thrifty genotype" hypothesis, the same genes that helped our ancestors survive occasional famines are now being challenged by environments in which food is plentiful year round. (cdc.gov)
  • and a focus on both the social and biological contexts of behavior. (nih.gov)
  • Describe a systems perspective and its relevance to developing knowledge of human behavior in the social environment. (academizzed.com)
  • By studying the intricate connections and interactions between people and the different systems in which they live, such as family systems, community systems, and societal systems, a systems viewpoint is a means of understanding human behavior. (academizzed.com)
  • The systems approach stresses the interconnection of systems and the reciprocal link between people and their environment, making it a useful foundation for comprehending human behavior in the social context. (academizzed.com)
  • Nervous System - The system that coordinates the interaction of the body with the world around it, integrating incoming sensory information, processing and sending information, and commanding the body to respond or move. (fi.edu)
  • We used an integrative approach to comprehensively assess the interactions between 1.6 million data points, encompassing a range of environmental exposures, health, and gene expression levels, coupled with whole-genome genetic variation. (nature.com)
  • We chose to use expression-curves rather than single, specific, time-point measurements to capture this biological variation. (cambridge.org)
  • There is evidence of a relationship between the quality of maternal-infant interaction and methylation of this gene though these are small effects in response to a relatively small variation in interaction," said Elizabeth Holdsworth, a Washington State University biological anthropologist and lead author of the study. (newindianexpress.com)
  • Nevertheless, the variation in how people respond to the same environment suggests that genes do play a role in the development of obesity. (cdc.gov)
  • During gene expression, the DNA is first copied into RNA. (wikipedia.org)
  • and (3) regulatory sequences control gene expression but are not part of the gene itself. (wikipedia.org)
  • The resulting changes in gene expression and phenotype are analyzed in interdisciplinary approaches at the genome, proteome and foremost at the metabolome level. (leibniz-gemeinschaft.de)
  • Maternal PON1 status (PON1 activity levels, the most important measurement, and functional Q192R phenotype) modulates the detrimental effects of exposure to the OP chlorpyrifos oxon on fetal brain gene expression and biomarkers of exposure. (cdc.gov)
  • Finally, we capture four expression quantitative trait loci that interact with the environment (air pollution). (nature.com)
  • After attributing a regional and/or continental ancestry to each individual using genome-wide polymorphism data, we are able to capture the effect of different environmental exposures on gene expression and health-related traits, while simultaneously controlling for genetic relatedness and migration. (nature.com)
  • Aberrant expression of DPPA2 and HIWI genes in colorectal cancer and their impacts on poor prognosis. (nih.gov)
  • Gene expression profiling of Leishmania (Leishmania). (cambridge.org)
  • Gene expression profiling is increasingly used in the field of infectious diseases for characterization of host, pathogen and the nature of their interaction. (cambridge.org)
  • The limitations and possibilities associated with expression profiling in intracellular amastigotes and promastigotes were assessed through a series of comparative experiments in which technical and biological parameters were scrutinized. (cambridge.org)
  • On the biological level, we demonstrate that gene expression levels fluctuate during in vitro development of both intracellular amastigotes and promastigotes. (cambridge.org)
  • However, these changes are superimposed in individuals with reduced brain volume, especially in the hippocampus, and other developmental abnormalities, such as reduced dendritic arborizations, decreased number of spines, spine atrophy, and abnormalities of spine orientation in pyramidal neurons. (medscape.com)
  • Some viruses have an RNA genome so the genes are made of RNA that may function directly without being copied into RNA. (wikipedia.org)
  • Further, in order to capture gene-by-environment interactions through eQTL analyses, we combine whole-transcriptome RNA-Sequencing profiles with whole-genome genotyping and extensive fine-scale environmental exposure data. (nature.com)
  • To maximize the potential disease relevance, genes with a genome-wide significant excess burden of loss-of-function mutations in NPDs such as intellectual disability/developmental delay, autism spectrum disorder, and schizophrenia are the focus. (nih.gov)
  • Nineteen types of so-called purinergic receptors are known to be stimulated by these extracellular nucleotides, and the receptors are known to control a broad range of biological characteristics with relevance to autism, such as impaired language and social skills. (technologynetworks.com)
  • These genes make up different DNA sequences called genotypes. (wikipedia.org)
  • We redesigned sequences of genes and their promoters that control their functions across diverse organisms," said Jaymin Patel, a Yale graduate student in the labs of Crawford and Isaacs and first author of the study. (yale.edu)
  • No matter how these animals fit into their environment, there is an underlying need to understand their behaviour, population dynamics, physiology, and the way they interact with other species and their environments. (ed.ac.uk)
  • Dynamics/ drives/motivations: Developmental explanations of how life course and needs/drives interact. (the-mouse-trap.com)
  • Genes and environmental factors interact. (technologynetworks.com)
  • Nurture refers to the environments, social as well as physical, that influence our development, everything from the womb in which we develop before birth to the homes in which we grow up, the schools we attend, and the many people with whom we interact. (nobaproject.com)
  • The study will research in detail how ELS converts into biological signals embedded simultaneously or sequentially in the brain, the cardiovascular and metabolic systems. (plos.org)
  • The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. (wikipedia.org)
  • Diagnostic clinical relevance of developmental pluripotency-associated 2 (DPPA2) in colorectal cancer. (nih.gov)
  • And the genes encoding these metabolites are often silenced, rendering the discovery of natural products very challenging. (yale.edu)
  • Metabolites were isolated based on biological activity and were characterized using tandem mass spectrometry, multidimensional nuclear magnetic resonance, and Mosher ester analysis, leading to the discovery of a new family of bacterial tetrahydropyridine alkaloids, koreenceine A to D (metabolites 1 to 4). (nih.gov)
  • We expand the known repertoire of antibiotics produced by Pseudomonas in the rhizosphere and demonstrate the role of the metabolites in interactions with other rhizosphere bacteria. (nih.gov)
  • The Scalable and Systematic Neurobiology of Psychiatric and Neurodevelopmental Disorder Risk Genes (SSPsyGene) Consortium: Assay and Data Generation Centers (RM1) (RFA-MH-24-145). (nih.gov)
  • While the long-term goal of the SSPsyGene Consortium is to build a comprehensively annotated resource describing the CNS function of all neurodevelopmental and psychiatric disorder risk genes, the current target for the initiative is 100-250 protein coding genes. (nih.gov)
  • A genetic screen in P. koreensis identified a previously uncharacterized biosynthetic gene cluster responsible for the inhibitory activity. (nih.gov)
  • While theoretical models are well defined, little is known of the G × E interactions in humans. (nature.com)
  • By identifying disruptions in the biological systems we can make better predictions about resulting effects for both natural organisms and humans on both short and long term scales. (lu.se)
  • OBJECTIVES: In this study, we utilize high-resolution metabolomics (HRM) to identify internal exposure and biological responses underlying PCB and multigenerational PBB exposure for participants enrolled in the Michigan PBB Registry. (bvsalud.org)
  • Like compounds from biological sources and low-molecular-weight nonoccupational asthma, occupational asthma is probably the chemicals cause occupational asthma after a latent period of result of multiple genetic, environmental, and behavioral exposure. (cdc.gov)
  • Our research interests are focused on various contaminants, including endocrine disrupters derived from plastics, and exposure effects from chemicals used in urban environments. (lu.se)
  • Genes - The smallest heritable unit of DNA, passed from parent to child. (fi.edu)
  • This definition includes genes that do not encode proteins (not all transcripts are messenger RNA). (wikipedia.org)
  • The main topic is addressed from multiple perspectives ranging from pathogenesis (including developmental and maintaining factors) to treatment. (springer.com)
  • It's wrong to think of genes and the environment as separate and independent factors. (technologynetworks.com)
  • By clarifying the roles of both host- (genetic) and virus- (environment) specific factors that contribute to the frequency and severity of viral LRTI, it may be possible to determine if severe LRTIs cause asthma, or if asthma susceptibility predisposes patients to severe LRTI in response to viral infection. (atsjournals.org)
  • Most obesity, however, probably results from complex interactions among multiple genes and environmental factors that remain poorly understood (multifactorial obesity). (cdc.gov)
  • Doing a better job of explaining obesity in terms of genes and environment factors could help encourage people who are trying to reach and maintain a healthy weight. (cdc.gov)
  • Ident- cult to deduce interaction rules from observations of the ified transcription factors for specific cell fates are, for entire system. (lu.se)
  • Exactly how behavioral inhibition and impulsivity are shaped by the environment, both early in life and throughout development, can be studied in preclinical models that allow precise control over the environment. (frontiersin.org)
  • We therefore set out to examine the effect of a complex environment during adolescence -whether primed by early life adversity or not- on behavioral inhibition and impulsivity in male rats. (frontiersin.org)
  • There are two types of molecular genes: protein-coding genes and non-coding genes. (wikipedia.org)
  • This product may be protein (as is the case in the majority of genes) or may be RNA (as is the case of genes that code for tRNA and rRNA). (wikipedia.org)
  • In a study conducted with Liz Handley, for example, Cicchetti found that a particular allele of the C-reactive protein (CRP) gene may be tied to lower serum levels of high-sensitivity CRP, an indicator of lower levels of stress and inflammation. (psychologicalscience.org)
  • The goal of this initiative is to fill a very specific knowledge gap area, which is that many protein-coding genes are now associated with NPD risk, but their basic neurobiology remains poorly understood. (nih.gov)
  • We offer 12 different biological sciences subject areas, including zoology. (ed.ac.uk)
  • However, if you are applying to our Biological Sciences programmes you should only select one programme within this subject area. (ed.ac.uk)
  • All Biological Sciences students study the same core courses in Year 1. (ed.ac.uk)
  • This gene encodes a receptor involved in the regulation of the HPA axis - the interaction between the body's hypothalamus, pituitary and adrenal glands. (newindianexpress.com)
  • or (3) incorporating b-BSSR into other biological, clinical, or translational research. (nih.gov)
  • From ∼ 1000 individuals of a founder population in Quebec, we reveal a substantial impact of the environment on the transcriptome and clinical endophenotypes, overpowering that of genetic ancestry. (nature.com)
  • On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations. (cdc.gov)
  • There are many different ways to use the term "gene" based on different aspects of their inheritance, selection, biological function, or molecular structure but most of these definitions fall into two categories, the Mendelian gene or the molecular gene. (wikipedia.org)
  • Although there is strong evidence for the role of a genetic component in language disorder, we do not know which genes contribute to this disorder or how the inheritance of language problems work. (brookes.ac.uk)
  • Uncovering the interaction between genomes and the environment is a principal challenge of modern genomics and preventive medicine. (nature.com)
  • this is particularly a delicate task for intracellular amastigotes and for specific 'sensory' genes. (cambridge.org)
  • multicellular interactions, including intracellular and Addresses intercellular biochemical signaling. (lu.se)
  • Lastly, we present a complex systems framework for the multifactorial interactions that often lead to long-term sequelae, citing current and emerging opportunities for research to prevent chronic diseases of infectious etiology and discussing the potential impact of these benefits. (cdc.gov)
  • Over the past 35 years, Dante Cicchetti, McKnight Presidential Chair and William Harris Professor of Child Psychology and Psychiatry at the Institute of Child Development, University of Minnesota, has examined the effects of child maltreatment on multiple psychological and biological domains. (psychologicalscience.org)
  • Correlations were analyzed, and mixed-effect models were fitted to explore developmental and predictive effects. (kcl.ac.uk)
  • Serious' effects are those that evoke failure in a biological system and can lead to morbidity or mortality (e.g., acute respiratory distress or death). (cdc.gov)
  • The genetic interactions between the microbiome and human cells offer great promise in improving the understanding of disease and developing new medical therapies. (yale.edu)
  • The evolving concept of the gene, of genetic interactions and gene networks, as well as chromosome mechanics will be the focus of the course. (princeton.edu)
  • Usage of the term "having a gene" (e.g., "good genes," "hair color gene") typically refers to containing a different allele of the same, shared gene. (wikipedia.org)
  • Today's living environment has become drastically complex and demanding, with rapidly changing technologies asking for constant attention and quick adaptation. (frontiersin.org)
  • One explanation that is often cited is the mismatch between today's environment and "energy-thrifty genes" that multiplied in the distant past, when food sources were unpredictable. (cdc.gov)
  • These courses provide a broad base of biological knowledge as well as integrating fundamental computational, practical and analytical skills to help you prepare for your future. (ed.ac.uk)
  • NC development is tightly regulated by finely tuned gene regulatory network (GRN) and orchestrated hierarchically. (biomedcentral.com)
  • Developmental Therapeutics focuses on the discovery, development, and delivery of new anticancer therapies. (cancer.gov)
  • Biological: This part focuses on assessing the person's physical health, taking into account their medical background, current prescriptions, and any underlying health issues. (academizzed.com)
  • The researchers found that the mothers showing awkward or neutral behaviour toward their infant correlated with a small increase of methylation on the NR3C1 gene, the study said. (newindianexpress.com)
  • As the rodent approximation of our complex society, we housed animals post-weaning in an enriched laboratory housing, which is widely used as an experimental condition to provide a more complex environment to the animal compared to standard housing. (frontiersin.org)
  • In the present study, we examined the effect of a complex rearing environment during adolescence on attention and behavioral inhibition in adult male rats. (frontiersin.org)
  • This gene has been associated with regulating the body's response to stress, the study said. (newindianexpress.com)
  • The researchers first analyzed data from an observational study of the mothers sharing a picture book with their children at 12 months, in which their interactions were coded on warmth. (newindianexpress.com)
  • The developmental timing and duration of maltreatment also have been shown to play important roles in gene-environment interactions. (psychologicalscience.org)